breseq  version 0.35.4  revision f352f80f4bc9
mutation predictions | marginal predictions | summary statistics | genome diff | command line log

Predicted mutations
evidence position mutation freq annotation gene description
RA 2,577 C→A 52.9% G747G (GGC→GGA thrA → Bifunctional aspartokinase/homoserine dehydrogenase 1
RA 5,144 G→A 100% intergenic (+124/‑90) thrC → / → yaaX L‑threonine synthase/DUF2502 family putative periplasmic protein
RA 10,444 G→T 100% F17L (TTC→TTA satP ← succinate‑acetate transporter
RA 12,901 G→A 100% D247N (GAT→AAT)  dnaK → chaperone Hsp70, with co‑chaperone DnaJ
RA 25,013 G→T 5.3% D875Y (GAC→TAC)  ileS → isoleucyl‑tRNA synthetase
RA 25,546 G→T 100% D114Y (GAC→TAC)  lspA → prolipoprotein signal peptidase (signal peptidase II)
RA 29,139 G→T 100% G256C (GGT→TGT)  dapB → dihydrodipicolinate reductase
RA 31,450 G→T 8.5% G212C (GGC→TGC)  carB → carbamoyl‑phosphate synthase large subunit
RA 32,641 G→A 5.6% D609N (GAC→AAC)  carB → carbamoyl‑phosphate synthase large subunit
RA 41,442 G→T 41.4% R164S (CGC→AGC)  caiT ← putative transporter
RA 42,150 G→A 58.4% intergenic (‑219/‑253) caiT ← / → fixA putative transporter/anaerobic carnitine reduction putative electron transfer flavoprotein subunit
RA 46,091 G→T 5.8% V95V (GTG→GTT yaaU → putative transporter
RA 49,840 G→T 100% A6A (GCG→GCT folA → dihydrofolate reductase
RA 51,352 A→T 35.3% G85G (GGT→GGA apaG ← protein associated with Co2+ and Mg2+ efflux
RA 55,590 G→T 100% T507K (ACG→AAG)  lptD ← LPS assembly OM complex LptDE, beta‑barrel component
RA 56,677 G→T 100% R145S (CGC→AGC)  lptD ← LPS assembly OM complex LptDE, beta‑barrel component
RA 70,249 A→C 35.2% C254G (TGC→GGC)  thiP ← thiamine, thiamine pyrophosphate ABC transporter permease; ThiBPQ thiamine, thiamine pyrophosphate importer
RA 76,821 G→T 12.1% G177G (GGC→GGA leuC ← 3‑isopropylmalate dehydratase large subunit
RA 80,123 C→T 100% G25S (GGC→AGC)  leuL ← leu operon leader peptide
RA 81,562 C→A 100% I236I (ATC→ATA leuO → global transcription factor
RA 84,481 G→A 5.2% intergenic (+146/‑34) ilvH → / → cra acetolactate synthase 3, small subunit, valine‑sensitive/transcriptional repressor‑activator for carbon metabolism
RA 85,890 G→T 40.5% intergenic (+371/‑231) cra → / → mraZ transcriptional repressor‑activator for carbon metabolism/RsmH methytransferase inhibitor
RA 86,729 G→T 6.3% R50L (CGT→CTT)  rsmH → 16S rRNA m(4)C1402 methyltransferase, SAM‑dependent
RA 92,294 C→A 37.5% R386R (CGC→CGA murF → UDP‑N‑acetylmuramoyl‑tripeptide:D‑alanyl‑D‑ alanine ligase
RA 93,391 G→T 58.6% T301T (ACG→ACT mraY → phospho‑N‑acetylmuramoyl‑pentapeptide transferase
RA 95,873 G→T 45.6% S328S (TCG→TCT ftsW → lipid II flippase; integral membrane protein involved in stabilizing FstZ ring during cell division
RA 97,521 C→A 100% A90A (GCC→GCA murC → UDP‑N‑acetylmuramate:L‑alanine ligase
RA 97,893 T→A 39.6% F214L (TTT→TTA murC → UDP‑N‑acetylmuramate:L‑alanine ligase
RA 103,467 G→T 100% D142Y (GAT→TAT)  lpxC → UDP‑3‑O‑acyl N‑acetylglucosamine deacetylase
RA 103,902 T→A 5.1% F287I (TTC→ATC)  lpxC → UDP‑3‑O‑acyl N‑acetylglucosamine deacetylase
RA 104,561 G→T 100% A124S (GCG→TCG)  secM → regulator of secA translation
RA 104,582 A→T 36.7% T131S (ACG→TCG)  secM → regulator of secA translation
RA 110,883 A→T 8.7% Y318F (TAC→TTC)  guaC → GMP reductase
RA 116,052 G→T 5.8% L95L (CTG→CTT ampE → ampicillin resistance inner membrane protein; putative signaling protein in beta‑lactamase regulation
RA 118,873 G→T 100% D99Y (GAC→TAC)  pdhR → pyruvate dehydrogenase complex repressor; autorepressor
RA 119,467 G→T 52.4% intergenic (+124/‑37) pdhR → / → aceE pyruvate dehydrogenase complex repressor; autorepressor/pyruvate dehydrogenase, decarboxylase component E1, thiamine triphosphate‑binding
RA 124,371 C→A 43.0% intergenic (+297/‑28) aceF → / → lpd pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2/lipoamide dehydrogenase, E3 component is part of three enzyme complexes
RA 126,667 G→T 5.4% R361R (CGG→AGG)  yacH ← uncharacterized protein
RA 134,028 G→T 56.2% A153A (GCG→GCT cueO → multicopper oxidase (laccase)
RA 134,203 G→T 8.9% D212Y (GAT→TAT)  cueO → multicopper oxidase (laccase)
RA 134,652 G→T 35.2% M361I (ATG→ATT cueO → multicopper oxidase (laccase)
RA 142,460 T→A 100% F298Y (TTC→TAC)  yadE → putative polysaccharide deacetylase lipoprotein
RA 146,343 G→T 43.2% T366T (ACC→ACA yadC ← putative fimbrial‑like adhesin protein
RA 151,620 C→A 36.7% K98N (AAG→AAT htrE ← putative outer membrane usher protein
RA 153,472 G→T 100% intergenic (‑102/+268) yadN ← / ← folK putative fimbrial‑like adhesin protein/2‑amino‑4‑hydroxy‑6‑hydroxymethyldihyropteridine pyrophosphokinase
RA 158,287 C→A 100% D78Y (GAC→TAC)  ligT ← 2'‑5' RNA ligase
RA 161,068 A→C 11.8% intergenic (+47/‑149) hrpB → / → mrcB putative ATP‑dependent helicase/fused glycosyl transferase and transpeptidase
RA 172,107 G→T 35.7% E172* (GAA→TAA)  clcA → H(+)/Cl(‑) exchange transporter
RA 172,979 G→T 30.8% A462A (GCG→GCT clcA → H(+)/Cl(‑) exchange transporter
RA 175,636 T→G 11.2% K2T (AAA→ACA)  mtn ← 5'‑methylthioadenosine/S‑adenosylhomocysteine nucleosidase
RA 176,783 G→T 54.5% D354Y (GAT→TAT)  dgt → deoxyguanosine triphosphate triphosphohydrolase
RA 176,864 C→T 34.4% L381L (CTA→TTA)  dgt → deoxyguanosine triphosphate triphosphohydrolase
RA 183,669 C→A 5.2% R490L (CGC→CTC)  glnD ← uridylyltransferase
RA 186,279 A→T 36.2% noncoding (81/136 nt) tff → novel sRNA, function unknown
RA 189,654 G→T 5.4% R99L (CGT→CTT)  frr → ribosome recycling factor
RA 194,124 C→A 39.1% I364I (ATC→ATA rseP → inner membrane zinc RIP metalloprotease; RpoE activator, by degrading RseA; cleaved signal peptide endoprotease
RA 201,962 A→T 57.4% D117V (GAT→GTT)  dnaE → DNA polymerase III alpha subunit
RA 207,624 G→T 5.2% D487Y (GAT→TAT)  ldcC → lysine decarboxylase 2, constitutive
RA 215,833 G→T 28.3% N83K (AAC→AAA tsaA ← tRNA‑Thr(GGU) m(6)t(6)A37 methyltransferase, SAM‑dependent
RA 217,932 A→C 59.7% I59M (ATT→ATG metI ← DL‑methionine transporter subunit
RA 222,983 G→T 5.8% noncoding (738/2904 nt) rrlH → 23S ribosomal RNA of rrnH operon
RA 230,579 C→T 100% E231K (GAA→AAA)  gloB ← hydroxyacylglutathione hydrolase
RA 232,860 G→T 100% D103Y (GAT→TAT)  dnaQ → DNA polymerase III epsilon subunit
RA 233,931 G→A 28.9% S37N (AGT→AAT)  yafT → lipoprotein
RA 236,234 A→T 53.2% V148E (GTG→GAG)  yafV ← putative NAD(P)‑binding C‑N hydrolase family amidase
RA 238,195 G→T 100% V532V (GTC→GTA fadE ← acyl coenzyme A dehydrogenase
RA 247,002 G→T 36.1% pseudogene (444/756 nt) lafU → pseudogene, lateral flagellar motor protein fragment
RA 250,880 G→T 34.5% P442T (CCG→ACG)  pepD ← aminoacyl‑histidine dipeptidase (peptidase D)
RA 253,769 C→T 8.8% V252V (GTC→GTT frsA → fermentation‑respiration switch protein; PTS Enzyme IIA(Glc)‑binding protein; pNP‑butyrate esterase activity
RA 258,054 G→T 49.2% G281C (GGC→TGC)  proA → gamma‑glutamylphosphate reductase
RA 262,114 C→A 57.0% D51Y (GAT→TAT)  yafY ← lipoprotein, inner membrane; overproduction stimulates degP expression; CP4‑6 prophage
RA 266,127 C→A 36.5% pseudogene (139/258 nt) insN → pseudogene, IS911 transposase A;IS, phage, Tn; Transposon‑related functions; extrachromosomal; transposon related
RA 274,735 A→T 100% pseudogene (138/348 nt) afuB ← pseudogene, CP4‑6 prophage; ABC transporter permease family;Phage or Prophage Related
RA 278,052 G→T 17.4% G22C (GGC→TGC)  yagE → 2‑keto‑3‑deoxy gluconate (KDG) aldolase; CP4‑6 prophage
RA 291,453 A→T 8.1% L452* (TTA→TAA)  intF ← CP4‑6 prophage; putative phage integrase
RA 295,092 G→T 31.1% G518G (GGC→GGA paoC ← PaoABC aldehyde oxidoreductase, Moco‑containing subunit
RA 302,428 G→T 5.1% P34Q (CCG→CAG)  ecpD ← polymerized tip adhesin of ECP fibers
RA 312,532 G→A 100% pseudogene (349/684 nt) ykgA ← pseudogene, AraC family;putative regulator; Not classified; putative ARAC‑type regulatory protein
RA 314,408 A→G 40.3% D435D (GAT→GAC rclA ← reactive chlorine stress species (RCS) resistance protein; pyridine nucleotide‑dependent disulfide oxidoreductase family
RA 317,205 G→A 50.6% intergenic (+413/‑114) rclR → / → ykgE reactive chlorine species (RCS)‑specific activator of the rcl genes/cysteine‑rich LutA family protein; putative electron transport chain YkgEFG component
RA 320,920 G→A 100% S52S (AGC→AGT ykgH ← putative inner membrane protein
RA 321,223 C→A 100% intergenic (‑148/+65) ykgH ← / ← betA putative inner membrane protein/choline dehydrogenase, a flavoprotein
RA 326,385 G→T 40.7% P404P (CCG→CCT betT → choline transporter of high affinity
RA 344,800 G→T 100% E136D (GAG→GAT prpB → 2‑methylisocitrate lyase
RA 345,384 G→C 5.3% intergenic (+101/‑339) prpB → / → prpC 2‑methylisocitrate lyase/2‑methylcitrate synthase
RA 347,382 G→T 44.4% E153* (GAA→TAA)  prpD → 2‑methylcitrate dehydratase
RA 360,317 C→A 48.2% intergenic (‑251/+344) lacZ ← / ← lacI pseudogene, truncated/DNA‑binding transcriptional repressor
RA 360,752 A→G 100% V331A (GTG→GCG)  lacI ← DNA‑binding transcriptional repressor
RA 361,806 G→A 100% intergenic (‑63/+14) lacI ← / ← mhpR DNA‑binding transcriptional repressor/mhp operon transcriptional activator
RA 362,159 G→T 100% I165I (ATC→ATA mhpR ← mhp operon transcriptional activator
RA 376,412 G→A 9.0% pseudogene (304/416 nt) yaiX ← pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase
RA 385,815 G→T 59.9% pseudogene (109/1458 nt) yaiT → pseudogene, autotransporter family;putative structure; Not classified; interrupted by IS3; putative flagellin structural protein
RA 388,341 G→T 8.8% S6* (TCA→TAA)  insE1 ← IS3 transposase A
RA 395,951 G→T 40.7% V143V (GTC→GTA ddlA ← D‑alanine‑D‑alanine ligase A
RA 396,883 A→G 92.9% Q14Q (CAA→CAG iraP → anti‑RssB factor, RpoS stabilzer during Pi starvation; anti‑adapter protein
RA 397,959 G→A 54.8% A253T (GCG→ACG)  phoA → bacterial alkaline phosphatase
RA 399,531 G→T 9.0% A125S (GCG→TCG)  yaiC → diguanylate cyclase, cellulose regualtor
RA 402,340 G→T 100% V160V (GTG→GTT aroL → shikimate kinase II
RA 406,075 C→A 100% P159Q (CCG→CAG)  mak → manno(fructo)kinase
RA 411,027 G→T 100% L61L (CTC→CTA sbcC ← exonuclease, dsDNA, ATP‑dependent
RA 421,799 C→A 100% I69I (ATC→ATA tgt → tRNA‑guanine transglycosylase
RA 425,143 G→T 57.9% T61T (ACG→ACT secF → SecYEG protein translocase auxillary subunit
RA 427,603 C→T 30.8% intergenic (‑134/+165) tsx ← / ← yajI nucleoside channel, receptor of phage T6 and colicin K/putative lipoprotein
RA 433,551 G→T 100% S14Y (TCC→TAC)  yajO ← 2‑carboxybenzaldehyde reductase
RA 433,738 A→C 48.4% intergenic (‑147/+33) yajO ← / ← dxs 2‑carboxybenzaldehyde reductase/1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring
RA 434,663 A→C 100% I324S (ATC→AGC)  dxs ← 1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring
RA 435,336 G→T 100% Q100K (CAG→AAG)  dxs ← 1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring
RA 437,672 T→A 100% V223E (GTG→GAG)  thiI → tRNA s(4)U8 sulfurtransferase
RA 444,489 G→A 100% R537C (CGT→TGT)  cyoB ← cytochrome o ubiquinol oxidase subunit I
RA 446,369 T→G 54.5% Q233P (CAG→CCG)  cyoA ← cytochrome o ubiquinol oxidase subunit II
RA 450,290 G→A 100% intergenic (+45/‑299) bolA → / → tig stationary‑phase morphogene, transcriptional repressor for mreB; also regulator for dacA, dacC, and ampC/peptidyl‑prolyl cis/trans isomerase (trigger factor)
RA 451,853 C→A 32.8% T422N (ACC→AAC)  tig → peptidyl‑prolyl cis/trans isomerase (trigger factor)
RA 453,656 T→A 44.0% S259T (TCC→ACC)  clpX → ATPase and specificity subunit of ClpX‑ClpP ATP‑dependent serine protease
RA 456,298 T→A 100% L652Q (CTG→CAG)  lon → DNA‑binding ATP‑dependent protease La
RA 456,588 G→T 100% D749Y (GAC→TAC)  lon → DNA‑binding ATP‑dependent protease La
RA 462,982 A→T 24.8% T39S (ACT→TCT)  cof → thiamine pyrimidine pyrophosphate hydrolase; HMP‑PP phosphatase
RA 465,341 A→C 41.8% I339L (ATT→CTT)  mdlA → putative multidrug transporter subunit of ABC superfamily, ATP‑binding component
RA 474,138 G→T 100% intergenic (‑65/+99) ylaB ← / ← ylaC putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase/DUF1449 family inner membrane protein
RA 475,502 T→A 37.9% intergenic (‑128/+44) maa ← / ← hha maltose O‑acetyltransferase/modulator of gene expression, with H‑NS
RA 475,805 C→A 100% A120A (GCG→GCT tomB ← Hha toxicity attenuator; conjugation‑related protein
RA 479,244 C→A 100% A206S (GCC→TCC)  acrB ← multidrug efflux system protein
RA 480,820 C→T 100% D86N (GAC→AAC)  acrA ← multidrug efflux system
RA 481,667 G→A 100% A151T (GCG→ACG)  acrR → transcriptional repressor
RA 486,912 C→A 40.6% I15I (ATC→ATA apt → adenine phosphoribosyltransferase
RA 498,579 G→T 45.6% A39E (GCG→GAG)  ybaL ← inner membrane putative NAD(P)‑binding transporter
RA 500,613 G→T 7.7% G82C (GGT→TGT)  ushA → bifunctional UDP‑sugar hydrolase/5'‑nucleotidase
RA 507,163 G→T 6.7% G23C (GGC→TGC)  glsA → glutaminase 1
RA 509,737 G→A 57.4% E97K (GAG→AAG)  cueR → copper‑responsive regulon transcriptional regulator
RA 511,170 G→T 32.3% V20V (GTC→GTA qmcA ← PHB domain membrane‑anchored putative protease
RA 511,619 A→T 33.7% Q82L (CAA→CTA)  fetA → iron exporter, ATP‑binding subunit, ABC transporter FetAB subunit; peroxide resistance protein
RA 522,859 T→G 10.3% S1381R (AGT→AGG rhsD → Rhs family putative polymorphic toxin
RA 523,413 G→T 5.8% pseudogene (6/708 nt) rhsH → pseudogene, Rhs familly protein
RA 523,781 G→T 13.4% pseudogene (374/708 nt) rhsH → pseudogene, Rhs familly protein
RA 524,334:1 +T 100% pseudogene (239/491 nt) ybbD → pseudogene
RA 525,631 C→A 6.0% R351L (CGC→CTC)  mnmH ← tRNA 2‑selenouridine synthase, selenophosphate‑dependent
RA 530,466 C→A 100% F365L (TTC→TTA gcl → glyoxylate carboligase
RA 538,153 A→C 5.4% E270D (GAA→GAC glxK → glycerate kinase II
RA 538,400 G→T 5.2% E353* (GAA→TAA)  glxK → glycerate kinase II
RA 542,200 Δ1 bp 100% coding (65/1668 nt) fdrA → putative NAD(P)‑binding acyl‑CoA synthetase
RA 546,491 G→T 100% V199V (GTG→GTT ybcF → putative carbonate kinase
RA 546,782 G→T 6.7% S296S (TCG→TCT ybcF → putative carbonate kinase
RA 549,397 G→T 100% intergenic (‑1/+2) lpxH ← / ← ppiB UDP‑2,3‑diacylglucosamine pyrophosphohydrolase/peptidyl‑prolyl cis‑trans isomerase B (rotamase B)
RA 552,831 A→T 38.9% F123I (TTC→ATC)  folD ← bifunctional 5,10‑methylene‑tetrahydrofolate dehydrogenase/ 5,10‑methylene‑tetrahydrofolate cyclohydrolase
RA 557,303 A→T 37.0% E717D (GAA→GAT sfmD → putative outer membrane export usher protein
RA 557,592 G→T 57.2% D814Y (GAC→TAC)  sfmD → putative outer membrane export usher protein
RA 560,966 G→T 10.0% L157I (CTC→ATC)  intD ← DLP12 prophage; putative phage integrase
RA 564,074 A→C 14.0% N102H (AAT→CAT)  emrE → DLP12 prophage; multidrug resistance protein
RA 566,710 G→T 43.1% G121V (GGC→GTC)  ybcL → inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family
RA 571,745 G→T 44.1% pseudogene (537/1040 nt) nmpC ← DLP12 prophage; truncated outer membrane porin (pseudogene);IS, phage, Tn; Phage or Prophage Related; outer membrane porin protein; locus of qsr prophage
RA 576,653 G→T 39.7% A122S (GCA→TCA)  nohD → DLP12 prophage; DNA packaging protein
RA 576,998 G→T 100% pseudogene (189/309 nt) aaaD → pseudogene; DLP12 prophage; tail fiber assembly protein family;Phage or Prophage Related
RA 580,102 G→T 41.7% intergenic (+216/+34) appY → / ← ompT global transcriptional activator; DLP12 prophage/DLP12 prophage; outer membrane protease VII (outer membrane protein 3b)
RA 581,203 A→T 100% intergenic (‑114/‑310) ompT ← / → pauD DLP12 prophage; outer membrane protease VII (outer membrane protein 3b)/tRNA‑OTHER
RA 583,341 T→G 100% S33R (AGT→CGT)  ybcH ← PRK09936 family protein
RA 607,931 G→A 100% S7F (TCC→TTC)  fepA ← iron‑enterobactin outer membrane transporter
RA 615,143 C→A 6.9% T171T (ACG→ACT fepC ← iron‑enterobactin transporter subunit
RA 619,048 C→A 61.2% A307S (GCC→TCC)  fepB ← iron‑enterobactin transporter subunit
RA 625,364 G→T 100% G5G (GGG→GGT cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 630,742 C→A 39.8% E31* (GAA→TAA)  ybdM ← Spo0J family protein, ParB‑like nuclease domain
RA 631,999 C→A 36.1% P9P (CCG→CCT ybdN ← PAPS reductase‑like domain protein
RA 632,286 C→A 50.5% E263D (GAG→GAT ybdO ← putative DNA‑binding transcriptional regulator
RA 639,231 G→A 100% L65F (CTT→TTT)  rnk ← regulator of nucleoside diphosphate kinase
RA 647,234 C→T 53.8% E27K (GAA→AAA)  citC ← [citrate [pro‑3S]‑lyase] ligase
RA 647,422 G→T 100% intergenic (‑110/‑269) citC ← / → citA [citrate [pro‑3S]‑lyase] ligase/sensory histidine kinase in two‑component regulatory system with CitB
RA 647,509 T→C 100% intergenic (‑197/‑182) citC ← / → citA [citrate [pro‑3S]‑lyase] ligase/sensory histidine kinase in two‑component regulatory system with CitB
RA 648,056 C→A 100% F122L (TTC→TTA citA → sensory histidine kinase in two‑component regulatory system with CitB
RA 648,368 G→T 5.9% A226A (GCG→GCT citA → sensory histidine kinase in two‑component regulatory system with CitB
RA 651,666 G→A 8.0% intergenic (‑242/‑347) dcuC ← / → pagP anaerobic C4‑dicarboxylate transport/phospholipid:lipid A palmitoyltransferase
RA 652,865 Δ1 bp 100% coding (118/210 nt) cspE → constitutive cold shock family transcription antitermination protein; negative regulator of cspA transcription; RNA melting protein; ssDNA‑binding protein
RA 662,108 A→T 100% V522V (GTT→GTA mrdA ← transpeptidase involved in peptidoglycan synthesis (penicillin‑binding protein 2)
RA 662,631 C→A 100% R348L (CGC→CTC)  mrdA ← transpeptidase involved in peptidoglycan synthesis (penicillin‑binding protein 2)
RA 664,243 C→A 40.4% D84Y (GAT→TAT)  rsfS ← ribosomal silencing factor
RA 666,998 G→T 35.2% L22I (CTT→ATT)  holA ← DNA polymerase III, delta subunit
RA 667,348 G→T 62.9% Q99K (CAG→AAG)  lptE ← LPS assembly OM complex LptDE, lipoprotein component
RA 668,230 C→A 5.0% L670L (CTG→CTT leuS ← leucyl‑tRNA synthetase
RA 672,142 T→A 55.5% intergenic (‑139/‑25) ybeQ ← / → ybeR Sel1 family TPR‑like repeat protein/uncharacterized protein
RA 679,765 G→T 41.7% S35Y (TCT→TAT)  rihA ← ribonucleoside hydrolase 1
RA 693,739 G→T 54.2% H299N (CAC→AAC)  asnB ← asparagine synthetase B
RA 705,588 C→A 100% intergenic (+16/+68) chiQ → / ← fur chitosugar‑induced verified lipoprotein/ferric iron uptake regulon transcriptional repressor; autorepressor
RA 706,097 A→C 62.2% T2T (ACT→ACG
*29G (TGA→GGA) 
fur ←
uof ←
ferric iron uptake regulon transcriptional repressor; autorepressor
ryhB‑regulated fur leader peptide
RA 709,827 G→T 41.9% D272Y (GAT→TAT)  pgm → phosphoglucomutase
RA 723,846 A→C 37.5% W115G (TGG→GGG)  kdpA ← potassium translocating ATPase, subunit A
RA 724,813 A→T 100% intergenic (+17/‑226) ybfA → / → rhsC DUF2517 family protein/Rhs family putative polymorphic toxin
RA 725,650 G→T 30.4% P204P (CCG→CCT rhsC → Rhs family putative polymorphic toxin
RA 729,456 G→A 54.7% R75R (AGG→AGA ybfB → putative membrane protein
RA 732,494 G→T 56.9% pseudogene (214/1137 nt) ybfL → pseudogene, DDE domain transposase family;putative factor; Not classified; putative receptor protein
RA 733,539 G→A 9.0% intergenic (+122/‑9) ybfL → / → ybfD pseudogene, DDE domain transposase family;putative factor; Not classified; putative receptor protein/H repeat‑associated putative transposase
RA 734,498 C→A 6.7% I14I (ATC→ATA ybgA → DUF1722 family protein
RA 735,817 G→T 37.6% L285L (CTG→CTT phr → deoxyribodipyrimidine photolyase, FAD‑binding
RA 738,124:1 +T 44.7% intergenic (‑112/‑159) dtpD ← / → ybgI dipeptide and tripeptide permease D/NIF3 family metal‑binding protein
RA 741,706 G→T 8.5% A106S (GCC→TCC)  nei → endonuclease VIII/ 5‑formyluracil/5‑hydroxymethyluracil DNA glycosylase
RA 742,840 G→T 26.8% A129E (GCG→GAG)  abrB ← regulator of aidB expression; inner membrane protein
RA 743,278 G→A 34.5% intergenic (‑53/+99) abrB ← / ← ybgO regulator of aidB expression; inner membrane protein/putative fimbrial protein
RA 747,597 G→A 6.3% S10F (TCC→TTC)  ybgQ ← putative outer membrane protein
RA 748,327 G→A 6.5% intergenic (‑76/+314) ybgD ← / ← gltA putative fimbrial‑like adhesin protein/citrate synthase
RA 750,112 A→T 37.6% intergenic (‑188/‑521) gltA ← / → sdhC citrate synthase/succinate dehydrogenase, membrane subunit, binds cytochrome b556
RA 750,558 C→A 5.2% intergenic (‑634/‑75) gltA ← / → sdhC citrate synthase/succinate dehydrogenase, membrane subunit, binds cytochrome b556
RA 754,572 G→T 100% E137D (GAG→GAT sucA → 2‑oxoglutarate decarboxylase, thiamine triphosphate‑binding
RA 757,353 A→T 41.2% N126Y (AAT→TAT)  sucB → dihydrolipoyltranssuccinase
RA 759,000 C→A 100% F177L (TTC→TTA sucC → succinyl‑CoA synthetase, beta subunit
RA 761,420 C→T 10.1% intergenic (‑89/‑20) mngR ← / → mngA Transcriptional repressor for the mannosyl‑D‑glycerate catabolic operon/fused 2‑O‑a‑mannosyl‑D‑glycerate specific PTS enzymes: IIA component/IIB component/IIC component
RA 767,694 G→A 46.5% E261K (GAA→AAA)  cydA → cytochrome d terminal oxidase, subunit I
RA 779,699 G→T 33.7% S194* (TCG→TAG)  zitB ← zinc efflux system
RA 788,902 G→T 100% R115S (CGT→AGT)  modF ← fused molybdate transporter subunits of ABC superfamily: ATP‑binding components
RA 789,044 G→T 39.1% I67I (ATC→ATA modF ← fused molybdate transporter subunits of ABC superfamily: ATP‑binding components
RA 792,351 G→T 36.8% A114A (GCG→GCT modC → molybdate transporter subunit
RA 792,957 C→A 5.0% V316V (GTC→GTA modC → molybdate transporter subunit
RA 796,821 G→T 13.4% A203S (GCT→TCT)  ybhH → putative PrpF family isomerase
RA 800,488 G→T 100% V510V (GTG→GTT ybhJ → putative hydratase
RA 800,779 G→T 100% E607D (GAG→GAT ybhJ → putative hydratase
RA 816,152 C→A 38.7% intergenic (+108/‑97) ybhL → / → ybhM UPF0005 family inner membrane protein/UPF0005 family inner membrane protein
RA 816,292 A→T 36.4% H15L (CAC→CTC)  ybhM → UPF0005 family inner membrane protein
RA 818,362 G→T 7.8% G278G (GGC→GGA clsB ← cardiolipin synthase 2
RA 825,641 G→T 40.5% A153A (GCC→GCA ybiH ← DUF1956 domain‑containing tetR family putative transcriptional regulator
RA 828,374 G→T 100% V11V (GTC→GTA ybiA ← DUF1768 family protein
RA 828,819 G→T 5.3% P98P (CCG→CCT dinG → ATP‑dependent DNA helicase
RA 832,445 G→T 100% P213P (CCG→CCT ybiC → putative dehydrogenase
RA 834,794 C→A 5.1% D732Y (GAT→TAT)  fiu ← catecholate siderophore receptor Fiu
RA 837,698 G→A 36.2% intergenic (‑186/‑90) mcbA ← / → rlmF colanic acid mucoidy stimulation protein/23S rRNA m(6)A1618 methyltransferase, SAM‑dependent
RA 843,299 C→A 100% W54C (TGG→TGT glnH ← glutamine transporter subunit
RA 851,782 A→T 42.5% K122* (AAA→TAA)  ybiT → putative transporter subunit of ABC superfamily: ATP‑binding component
RA 863,745 T→A 40.3% F257Y (TTT→TAT)  gsiA → glutathione transporter ATP‑binding protein, ABC superfamily
RA 868,897 G→T 37.4% D155Y (GAC→TAC)  yliE → putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 870,070 G→T 6.4% V546F (GTC→TTC)  yliE → putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 876,447 G→A 100% D89N (GAT→AAT)  dacC → D‑alanyl‑D‑alanine carboxypeptidase (penicillin‑binding protein 6a)
RA 877,482 C→A 39.6% D237Y (GAT→TAT)  deoR ← deoxyribose‑5‑phosphate‑inducible deoxyribose operon transcriptional repressor; repressor of nupG and tsx
RA 879,085 G→T 100% intergenic (‑241/‑44) ybjG ← / → mdfA undecaprenyl pyrophosphate phosphatase/multidrug efflux system protein
RA 879,590 G→T 7.4% P154P (CCG→CCT mdfA → multidrug efflux system protein
RA 884,152 G→T 33.0% S375* (TCG→TAG)  ybjL ← putative transporter
RA 889,044 G→T 32.5% intergenic (+155/‑196) ybjN → / → potF negative regulator of motility; multicopy suppressor of coaA(Ts)/putrescine transporter subunit: periplasmic‑binding component of ABC superfamily
RA 890,555 G→T 42.5% D37Y (GAT→TAT)  potG → putrescine transporter subunit: ATP‑binding component of ABC superfamily
RA 898,457 G→T 41.7% intergenic (‑13/+5) artI ← / ← artP arginine transporter subunit/arginine transporter subunit
RA 907,596 G→T 43.6% P4Q (CCA→CAA)  hcr ← HCP oxidoreductase, NADH‑dependent
RA 911,375 G→T 5.3% F43L (TTC→TTA aqpZ ← aquaporin Z
RA 912,119 C→A 10.1% P64Q (CCG→CAG)  ybjD → putative OLD family ATP‑dependent endonuclease; DUF2813 family protein
RA 919,422 G→T 6.5% D235Y (GAT→TAT)  clpA → ATPase and specificity subunit of ClpA‑ClpP ATP‑dependent serine protease, chaperone activity
RA 920,805 G→T 5.0% D696Y (GAC→TAC)  clpA → ATPase and specificity subunit of ClpA‑ClpP ATP‑dependent serine protease, chaperone activity
RA 925,160 G→T 100% S420* (TCA→TAA)  cydD ← fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component
RA 925,355 A→T 37.5% L355Q (CTG→CAG)  cydD ← fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component
RA 925,957 A→T 37.5% I154I (ATT→ATA cydD ← fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component
RA 932,814 T→A 7.8% intergenic (+145/‑14) ftsK → / → lolA DNA translocase at septal ring sorting daughter chromsomes/lipoprotein chaperone
RA 943,573 G→T 100% A297S (GCC→TCC)  ycaM → putative transporter
RA 954,765 C→A 45.5% G166G (GGC→GGA aroA → 5‑enolpyruvylshikimate‑3‑phosphate synthetase
RA 955,568 A→T 59.6% intergenic (+17/‑152) aroA → / → ycaL 5‑enolpyruvylshikimate‑3‑phosphate synthetase/putative peptidase‑related chaperone
RA 963,256 G→A 37.0% D394N (GAT→AAT)  msbA → fused lipid transporter subunits of ABC superfamily: membrane component/ATP‑binding component
RA 968,415 G→T 100% S148* (TCG→TAG)  ycbC ← DUF218 superfamily protein
RA 976,873 C→A 36.5% A124E (GCG→GAG)  ldtD → murein L,D‑transpeptidase
RA 991,613 G→C 6.8% A263G (GCC→GGC)  ssuA ← aliphatic sulfonate binding protein, SsuABC ABC transporter
RA 997,965 G→T 62.6% D235Y (GAT→TAT)  elfG → putative fimbrial‑like adhesin protein
RA 1,011,409 C→A 6.3% *173L (TGA→TTA)  fabA ← beta‑hydroxydecanoyl thioester dehydrase
RA 1,016,392 G→A 6.2% intergenic (‑17/‑202) sulA ← / → sxy SOS cell division inhibitor/CRP‑S‑dependent promoter expression factor
RA 1,024,703 G→T 61.1% G241G (GGC→GGA rlmI ← 23S rRNA m(5)C1962 methyltransferase, SAM‑dependent
RA 1,040,472 A→T 6.1% V263E (GTG→GAG)  gfcE ← putative O‑antigen capsule outer membrane auxillary protein export channel
RA 1,048,928 C→A 100% E903* (GAA→TAA)  torS ← hybrid sensory histidine kinase in two‑component regulatory system with TorR
RA 1,049,407 G→T 100% T743K (ACG→AAG)  torS ← hybrid sensory histidine kinase in two‑component regulatory system with TorR
RA 1,073,243 C→A 37.3% G366C (GGT→TGT)  putA ← fused DNA‑binding transcriptional regulator/proline dehydrogenase/pyrroline‑5‑carboxylate dehydrogenase
RA 1,073,863 G→T 7.2% S159* (TCG→TAG)  putA ← fused DNA‑binding transcriptional regulator/proline dehydrogenase/pyrroline‑5‑carboxylate dehydrogenase
RA 1,077,911 A→C 100% K71N (AAA→AAC efeO → inactive ferrous ion transporter EfeUOB
RA 1,083,443 G→T 56.8% S624* (TCG→TAG)  pgaB ← poly‑beta‑1,6‑N‑acetyl‑D‑glucosamine (PGA) N‑deacetylase outer membrane export lipoprotein
RA 1,084,103 A→T 94.5% L404* (TTA→TAA)  pgaB ← poly‑beta‑1,6‑N‑acetyl‑D‑glucosamine (PGA) N‑deacetylase outer membrane export lipoprotein
RA 1,087,360 G→T 49.1% P129Q (CCG→CAG)  pgaA ← biofilm adhesin polysaccharide PGA secretin; OM porin; poly‑beta‑1,6‑N‑acetyl‑D‑glucosamine export protein
RA 1,095,709 C→A 14.2% intergenic (+59/‑43) ycdY → / → ycdZ redox enzyme maturation protein (REMP) chaperone for YcdX/DUF1097 family inner membrane protein
RA 1,098,939 A→T 17.1% intergenic (‑287/‑468) csgD ← / → csgB csgBAC operon transcriptional regulator/curlin nucleator protein, minor subunit in curli complex
RA 1,105,607 G→T 5.3% D273Y (GAC→TAC)  opgG → osmoregulated periplasmic glucan (OPG) biosynthesis periplasmic protein
RA 1,116,601 T→A 35.5% intergenic (‑190/+97) bssS ← / ← dinI biofilm regulator/DNA damage‑inducible protein I
RA 1,116,964 A→G 100% intergenic (‑21/+53) dinI ← / ← pyrC DNA damage‑inducible protein I/dihydro‑orotase
RA 1,132,098 G→T 43.5% M123I (ATG→ATT flgI → putative flagellar basal body protein
RA 1,132,494 T→A 40.3% I255I (ATT→ATA flgI → putative flagellar basal body protein
RA 1,151,485 G→T 8.4% V90F (GTT→TTT)  holB → DNA polymerase III, delta prime subunit
RA 1,151,750 G→T 100% R178L (CGC→CTC)  holB → DNA polymerase III, delta prime subunit
RA 1,152,278 G→T 100% E16* (GAA→TAA)  ycfH → putative DNase
RA 1,161,438 C→A 33.8% intergenic (+297/‑103) ycfP → / → ndh putative UPF0227 family esterase/respiratory NADH dehydrogenase 2/cupric reductase
RA 1,164,454 G→A 36.1% intergenic (‑166/‑75) ycfQ ← / → bhsA repressor for bhsA(ycfR)/biofilm, cell surface and signaling protein
RA 1,173,073 T→A 8.7% F100I (TTC→ATC)  lolE → lipoprotein‑releasing system transmembrane protein
RA 1,175,193 A→T 37.9% E36V (GAA→GTA)  cobB → deacetylase of acs and cheY, chemotaxis regulator
RA 1,176,357 G→T 9.8% L123I (CTC→ATC)  ycfZ ← inner membrane protein
RA 1,191,676 C→T 49.0% H366H (CAC→CAT icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,688 C→T 47.3% T370T (ACC→ACT icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,701 T→C 42.3% L375L (TTA→CTA) ‡ icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,703 A→G 41.8% L375L (TTA→TTG) ‡ icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,733 C→T 25.0% N385N (AAC→AAT icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,736 G→C 25.0% A386A (GCG→GCC icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,739 A→G 23.5% K387K (AAA→AAG icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,748 C→T 20.9% T390T (ACC→ACT icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,760 G→A 13.5% E394E (GAG→GAA icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,192,153 G→T 5.1% intergenic (+324/+170) icd → / ← ymfD e14 prophage; isocitrate dehydrogenase, specific for NADP+/e14 prophage; putative SAM‑dependent methyltransferase
RA 1,193,041 T→C 7.0% K218R (AAA→AGA)  ymfE ← e14 prophage; putative inner membrane protein
RA 1,193,873 G→T 100% intergenic (‑180/‑278) ymfE ← / → lit e14 prophage; putative inner membrane protein/e14 prophage; cell death peptidase, inhibitor of T4 late gene expression
RA 1,195,030 C→A 6.9% L294I (CTT→ATT)  lit → e14 prophage; cell death peptidase, inhibitor of T4 late gene expression
RA 1,196,362 G→A 10.9% R43W (CGG→TGG)  xisE ← e14 prophage; putative excisionase
RA 1,201,506 T→G 7.3% pseudogene (320/412 nt) beeE → pseudogene, portal protein family, e14 prophage;Phage or Prophage Related
RA 1,204,284 C→A 89.9% D98Y (GAT→TAT)  tfaE ← e14 prophage; putative tail fiber assembly protein
RA 1,204,620 C→A 8.1% pseudogene (456/501 nt) stfE ← pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
RA 1,206,494 T→A 5.4% I231I (ATT→ATA mcrA → putative 5‑methylcytosine/5‑hydroxymethylcytosine‑specific restriction nuclease; 5‑methylcytosine DNA binding protein; e14 prophage gene
RA 1,211,169 C→A 93.1% intergenic (‑238/‑76) bluF ← / → ycgZ anti‑repressor for YcgE, blue light‑responsive; FAD‑binding; has c‑di‑GMP phosphodiesterase‑like EAL domain, but does not degrade c‑di‑GMP/RcsB connector protein for regulation of biofilm and acid‑resistance
RA 1,214,456 T→C 35.2% N6N (AAT→AAC ymgF → inner membrane division septum protein
RA 1,219,533 A→G 100% intergenic (+170/+202) ycgI → / ← minE pseudogene/cell division topological specificity factor
RA 1,220,996 G→T 100% R181R (CGG→AGG)  minC ← cell division inhibitor
RA 1,224,292 G→A 100% D8N (GAT→AAT)  ycgN → UPF0153 family cysteine cluster protein
RA 1,224,528 G→T 8.2% L86L (CTG→CTT ycgN → UPF0153 family cysteine cluster protein
RA 1,226,292 T→A 100% C24S (TGT→AGT)  umuD → DNA polymerase V, subunit D
RA 1,227,613 C→A 38.6% N324K (AAC→AAA umuC → DNA polymerase V, subunit C
RA 1,228,591 G→T 100% intergenic (‑105/+41) dsbB ← / ← nhaB oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I/sodium:proton antiporter
RA 1,238,721 C→A 30.5% A29E (GCG→GAG)  emtA → lytic murein endotransglycosylase E
RA 1,251,120 T→A 44.0% T97S (ACC→TCC)  ycgV ← putative adhesin
RA 1,266,853 C→A 5.0% A151A (GCG→GCT chaA ← calcium/sodium:proton antiporter
RA 1,277,786 G→A 100% D823N (GAC→AAC)  narG → nitrate reductase 1, alpha subunit
RA 1,282,249 A→G 6.2% intergenic (+267/+273) narI → / ← rttR nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript
RA 1,282,421 A→G 11.0% intergenic (+439/+101) narI → / ← rttR nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript
RA 1,282,439 A→G 6.0% intergenic (+457/+83) narI → / ← rttR nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript
RA 1,288,669 A→T 58.4% intergenic (‑291/‑314) hns ← / → tdk global DNA‑binding transcriptional dual regulator H‑NS/thymidine kinase/deoxyuridine kinase
RA 1,310,130 T→A 5.6% K55* (AAA→TAA)  yciG ← KGG family protein
RA 1,322,140 T→A 100% T159S (ACG→TCG)  btuR ← cob(I)yrinic acid a,c‑diamide adenosyltransferase
RA 1,330,955 G→T 54.2% D290Y (GAT→TAT)  acnA → aconitate hydratase 1
RA 1,332,486 G→T 41.1% R800L (CGA→CTA)  acnA → aconitate hydratase 1
RA 1,334,048 G→T 36.5% E154D (GAG→GAT pgpB → phosphatidylglycerophosphatase B
RA 1,337,498 G→T 7.2% R30R (CGG→AGG)  osmB ← lipoprotein
RA 1,337,533 G→T 93.9% A18E (GCA→GAA)  osmB ← lipoprotein
RA 1,340,820 G→T 39.8% I60I (ATC→ATA gmr ← cyclic‑di‑GMP phosphodiesterase; csgD regulator; modulator of Rnase II stability
RA 1,340,901 A→T 38.1% S33S (TCT→TCA gmr ← cyclic‑di‑GMP phosphodiesterase; csgD regulator; modulator of Rnase II stability
RA 1,365,283 G→T 100% E271* (GAG→TAG)  ycjM → alpha amylase catalytic domain family protein
RA 1,372,069 G→T 45.2% E327D (GAG→GAT ycjS → putative NADH‑binding oxidoreductase
JC JC 1,376,043 IS5 (–) +4 bp 100% pseudogene (10‑13/126 nt) ycjV → pseudogene; putative ATP‑binding component of a transport system
RA 1,377,394 C→T 100% A275A (GCG→GCA ycjW ← LacI family putative transcriptional repressor
RA 1,386,008 G→T 100% Q35K (CAG→AAG)  ycjY ← S9 homolog non‑peptidase family protein
RA 1,388,406 G→T 100% R308L (CGC→CTC)  mppA → murein tripeptide (L‑ala‑gamma‑D‑glutamyl‑meso‑DAP) transporter subunit
RA 1,392,834 C→A 5.0% D16Y (GAC→TAC)  uspE ← stress‑induced protein
RA 1,406,275 C→A 12.9% L406F (TTG→TTT intR ← Rac prophage; integrase
RA 1,417,454 C→A 41.6% pseudogene (497/500 nt) ydaW → Rac prophage; pseudogene, DNA‑binding protein family;Phage or Prophage Related
RA 1,424,234 C→A 93.0% S310* (TCA→TAA)  stfR → Rac prophage; putative tail fiber protein
RA 1,424,558 C→A 42.1% A418E (GCG→GAG)  stfR → Rac prophage; putative tail fiber protein
JC JC 1,428,894 IS2 (–) +5 bp 100% intergenic (‑413/+317) ynaE ← / ← ttcC cold shock protein, Rac prophage/pseudogene, prophage Rac integration site ttcA duplication;Phage or Prophage Related
RA 1,429,517 G→T 6.6% I120I (ATC→ATA uspF ← stress‑induced protein, ATP‑binding protein
RA 1,439,518 C→A 100% S737S (TCC→TCA ydbH → putative membrane‑anchored protein, function unknown
RA 1,443,093 C→A 32.9% L440I (CTC→ATC)  feaB → phenylacetaldehyde dehydrogenase
RA 1,443,196 A→T 47.0% Q474L (CAG→CTG)  feaB → phenylacetaldehyde dehydrogenase
RA 1,444,739 G→A 30.6% P290S (CCC→TCC)  tynA ← tyramine oxidase, copper‑requiring
RA 1,448,466 C→A 8.3% Q95K (CAA→AAA)  paaA → ring 1,2‑phenylacetyl‑CoA epoxidase subunit
RA 1,451,422 A→T 59.1% T246S (ACG→TCG)  paaE → ring 1,2‑phenylacetyl‑CoA epoxidase, NAD(P)H oxidoreductase component
RA 1,454,724 G→T 100% G472C (GGT→TGT)  paaH → 3‑hydroxyadipyl‑CoA dehydrogenase, NAD+‑dependent
RA 1,457,811 A→T 43.5% T6S (ACT→TCT)  paaX → transcriptional repressor of phenylacetic acid degradation paa operon, phenylacetyl‑CoA inducer
RA 1,460,458 T→C 7.0% pseudogene (810/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,467 G→A 5.0% pseudogene (819/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,593 C→G 9.8% pseudogene (945/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,602 T→C 8.2% pseudogene (954/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,689 A→G 6.0% pseudogene (1041/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,695 T→G 7.8% pseudogene (1047/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,752 C→T 5.3% pseudogene (1104/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,861 G→A 7.7% pseudogene (1213/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,887 G→C 7.2% pseudogene (1239/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,481,236 G→T 49.3% intergenic (+16/‑256) hrpA → / → ydcF putative ATP‑dependent helicase/DUF218 superfamily protein, SAM‑binding
RA 1,488,630 C→A 35.2% T233T (ACG→ACT ydcI ← putative DNA‑binding transcriptional regulator
RA 1,493,345 A→T 13.3% T51S (ACG→TCG)  rimL → ribosomal‑protein‑L7/L12‑serine acetyltransferase
RA 1,499,199 A→T 41.6% V380E (GTG→GAG)  ydcO ← BenE family inner membrane putative transporter
RA 1,503,867 G→A 9.5% A35T (GCG→ACG)  hicB → antitoxin for the HicAB toxin‑antitoxin system
RA 1,519,349 T→A 100% K297* (AAA→TAA)  ansP ← L‑asparagine transporter
RA 1,520,062 G→T 11.3% A59E (GCG→GAG)  ansP ← L‑asparagine transporter
RA 1,521,126 G→A 9.7% intergenic (+5/‑71) yncG → / → yncH glutathione S‑transferase homolog/IPR020099 family protein
RA 1,529,506 C→T 10.4% G204S (GGC→AGC)  yddE ← PhzC‑PhzF family protein
RA 1,533,556 G→T 12.3% H1098N (CAC→AAC)  narZ ← nitrate reductase 2 (NRZ), alpha subunit
RA 1,540,526 C→A 43.4% intergenic (‑241/+19) yddL ← / ← yddG putative lipoprotein;putative membrane; Not classified; putative outer membrane porin protein/aromatic amino acid exporter
RA 1,542,441 T→A 31.7% F262I (TTT→ATT)  fdnG → formate dehydrogenase‑N, alpha subunit, nitrate‑inducible
RA 1,545,413 T→A 5.9% D232E (GAT→GAA fdnH → formate dehydrogenase‑N, Fe‑S (beta) subunit, nitrate‑inducible
RA 1,548,144 G→T 100% intergenic (‑49/+85) adhP ← / ← maeA ethanol‑active dehydrogenase/acetaldehyde‑active reductase/malate dehydrogenase, (decarboxylating, NAD‑requiring) (malic enzyme)
RA 1,552,629 C→A 53.8% D216Y (GAT→TAT)  ddpD ← D,D‑dipeptide permease system, ATP‑binding component
RA 1,554,588 G→T 38.3% A200E (GCG→GAG)  ddpB ← D‑ala‑D‑ala transporter subunit
RA 1,563,276 G→T 100% H491N (CAC→AAC)  gadC ← glutamate:gamma‑aminobutyric acid antiporter
RA 1,564,175 G→T 32.5% S191* (TCG→TAG)  gadC ← glutamate:gamma‑aminobutyric acid antiporter
RA 1,565,497 G→A 100% S269L (TCG→TTG)  gadB ← glutamate decarboxylase B, PLP‑dependent
RA 1,566,392 A→T 36.6% intergenic (‑90/+272) gadB ← / ← pqqL glutamate decarboxylase B, PLP‑dependent/putative periplasmic M16 family zinc metalloendopeptidase
RA 1,572,192 G→T 37.7% L470I (CTT→ATT)  yddA ← putative multidrug transporter subunit of ABC superfamily, membrane component/ATP‑binding component
RA 1,575,339 G→T 100% F481L (TTC→TTA ydeN ← putative Ser‑type periplasmic non‑aryl sulfatase
RA 1,586,871 G→T 6.0% intergenic (‑172/+51) hipB ← / ← yneO antitoxin of HipAB toxin‑antitoxin system/pseudogene, AidA homolog
RA 1,588,516 G→T 9.2% pseudogene (3729/5323 nt) yneO ← pseudogene, AidA homolog
RA 1,591,853 C→A 39.9% pseudogene (392/5323 nt) yneO ← pseudogene, AidA homolog
RA 1,591,894 C→A 36.2% pseudogene (351/5323 nt) yneO ← pseudogene, AidA homolog
RA 1,593,900 G→T 27.0% N189K (AAC→AAA lsrK ← autoinducer‑2 (AI‑2) kinase
RA 1,602,131 G→T 44.0% D177Y (GAT→TAT)  tam → trans‑aconitate methyltransferase
RA 1,603,440 G→A 94.5% intergenic (‑161/+46) yneE ← / ← uxaB bestrophin family putative inner membrane protein/altronate oxidoreductase, NAD‑dependent
RA 1,604,655 C→A 6.0% E95* (GAA→TAA)  uxaB ← altronate oxidoreductase, NAD‑dependent
RA 1,605,105 C→T 43.0% intergenic (‑168/+59) uxaB ← / ← yneF altronate oxidoreductase, NAD‑dependent/putative membrane‑bound diguanylate cyclase
RA 1,620,961 T→G 100% Q226P (CAA→CCA)  dcp ← dipeptidyl carboxypeptidase II
RA 1,628,207 G→A 100% G110E (GGA→GAA)  pinQ → Qin prophage; putative site‑specific recombinase
RA 1,646,993 C→T 46.8% intergenic (+28/+19) intQ → / ← ydfJ pseudogene, Qin prophage; phage integrase family;Phage or Prophage Related/pseudogene, MFS transporter family; interrupted by Qin prophage;Phage or Prophage Related; putative transport protein
RA 1,660,918 C→A 13.0% V187L (GTG→TTG)  ynfK ← putative dethiobiotin synthetase
RA 1,661,110 C→A 5.5% D123Y (GAT→TAT)  ynfK ← putative dethiobiotin synthetase
RA 1,661,763 C→A 100% P353P (CCG→CCT mlc ← glucosamine anaerobic growth regulon transcriptional repressor; autorepressor
RA 1,663,639 G→T 30.8% R71R (CGG→AGG)  ynfL ← LysR family putative transcriptional regulator
RA 1,670,193 G→T 6.8% A142E (GCG→GAG)  pntB ← pyridine nucleotide transhydrogenase, beta subunit
RA 1,680,642 C→A 9.6% E68D (GAG→GAT fumC ← fumarate hydratase (fumarase C),aerobic Class II
RA 1,689,180 T→G 56.4% E383D (GAA→GAC uidA ← beta‑D‑glucuronidase
RA 1,690,981 G→T 6.2% A110E (GCG→GAG)  uidR ← transcriptional repressor
RA 1,692,573 C→A 56.1% D289Y (GAT→TAT)  malI ← transcriptional repressor of Mal regulon
RA 1,696,612 A→T 100% E41D (GAA→GAT add → adenosine deaminase
RA 1,698,343 C→A 41.2% D75Y (GAT→TAT)  ydgJ ← putative oxidoreductase
RA 1,699,862 T→A 63.5% L119* (TTG→TAG)  ydgK → DUF2569 family inner membrane protein
RA 1,699,884 C→A 6.2% T126T (ACC→ACA ydgK → DUF2569 family inner membrane protein
RA 1,702,966 T→A 7.3% R597R (CGT→CGA rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,703,008 A→G 5.1% E611E (GAA→GAG rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,703,015 G→C 5.2% E614Q (GAA→CAA)  rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,711,397 C→T 100% R28Q (CGA→CAA)  tyrS ← tyrosyl‑tRNA synthetase
RA 1,718,636 G→T 46.7% L93I (CTT→ATT)  sodC ← superoxide dismutase, Cu, Zn, periplasmic
RA 1,723,809 G→T 63.5% E156* (GAA→TAA)  lhr → putative ATP‑dependent helicase
RA 1,725,272 G→T 5.2% A643A (GCG→GCT lhr → putative ATP‑dependent helicase
RA 1,727,497 G→T 9.2% R1385L (CGA→CTA)  lhr → putative ATP‑dependent helicase
RA 1,732,758 G→T 45.4% D220Y (GAC→TAC)  purR → transcriptional repressor, hypoxanthine‑binding
RA 1,747,774 A→T 6.4% F105Y (TTC→TAC)  ydhV ← putative oxidoreductase subunit
RA 1,751,673 T→G 39.2% intergenic (+306/‑5) pykF → / → lpp pyruvate kinase I/murein lipoprotein
RA 1,752,893 T→A 38.7% P30P (CCA→CCT ldtE ← murein L,D‑transpeptidase
RA 1,753,293 G→T 40.5% V85V (GTC→GTA sufE ← sulfur acceptor protein
RA 1,754,950 T→A 100% I367F (ATT→TTT)  sufD ← component of SufBCD Fe‑S cluster assembly scaffold
RA 1,764,150 G→T 54.8% D274Y (GAT→TAT)  ydiK → UPF0118 family inner membrane protein
RA 1,769,440 C→A 38.2% A166A (GCC→GCA aroD → 3‑dehydroquinate dehydratase
RA 1,770,281 T→A 100% D146E (GAT→GAA ydiF → putative acetyl‑CoA:acetoacetyl‑CoA transferase: alpha subunit/beta subunit
RA 1,777,451 C→A 59.0% A55E (GCG→GAG)  fadK → short chain acyl‑CoA synthetase, anaerobic
RA 1,778,497 G→T 13.0% A404S (GCC→TCC)  fadK → short chain acyl‑CoA synthetase, anaerobic
RA 1,788,981 A→T 41.6% S143R (AGT→AGA btuC ← vitamin B12 transporter subunit: membrane component of ABC superfamily
RA 1,791,509 C→A 33.4% P231P (CCG→CCT pheT ← phenylalanine tRNA synthetase, beta subunit
RA 1,795,267 A→T 33.6% F521I (TTC→ATC)  thrS ← threonyl‑tRNA synthetase
RA 1,795,354 G→T 5.4% R492S (CGT→AGT)  thrS ← threonyl‑tRNA synthetase
RA 1,798,234 G→T 47.5% pseudogene (460/1476 nt) arpB → pseudogene, ankyrin repeats
RA 1,798,834 G→A 37.5% pseudogene (1060/1476 nt) arpB → pseudogene, ankyrin repeats
RA 1,802,047 G→A 100% intergenic (+100/‑6) ydiZ → / → yniA uncharacterized protein/fructosamine kinase family protein
RA 1,803,109 C→T 54.2% A128T (GCC→ACC)  yniB ← putative inner membrane protein
RA 1,805,246 T→A 6.1% L19Q (CTG→CAG)  ydjN → putative transporter
RA 1,813,263 C→A 40.6% E148* (GAG→TAG)  chbR ← repressor of chb operon for N,N'‑diacetylchitobiose utilization
RA 1,813,497 C→A 11.2% D70Y (GAT→TAT)  chbR ← repressor of chb operon for N,N'‑diacetylchitobiose utilization
RA 1,816,882 C→A 10.8% A56A (GCC→GCA nadE → NAD synthetase, NH3/glutamine‑dependent
RA 1,821,696 A→T 55.7% L274Q (CTG→CAG)  astB ← succinylarginine dihydrolase
RA 1,822,975 C→A 47.4% A339A (GCG→GCT astD ← succinylglutamic semialdehyde dehydrogenase
RA 1,825,763 C→A 100% A159A (GCG→GCT astC ← succinylornithine transaminase, PLP‑dependent
RA 1,832,413 C→A 100% L315L (CTC→CTA ynjC → inner membrane putative ABC superfamily transporter permease
RA 1,833,730 C→A 100% R3S (CGT→AGT)  ynjE → molybdopterin synthase sulfurtransferase
RA 1,836,072 C→A 31.7% A109E (GCG→GAG)  nudG → CTP pyrophosphohydrolase; also hydrolyzes 2‑hydroxy‑dATP, 8‑hydroxy‑dGTP, 5‑hydroxy‑CTP, dCTP and 5‑methyl‑dCTP
RA 1,838,201 C→A 6.9% E310* (GAA→TAA)  ynjI ← inner membrane protein
RA 1,838,387 T→A 6.3% I248F (ATC→TTC)  ynjI ← inner membrane protein
RA 1,842,604 A→T 5.8% S110S (TCT→TCA ydjA ← putative oxidoreductase
RA 1,850,880 C→A 38.4% V102V (GTG→GTT ydjH ← putative kinase
RA 1,855,538 C→A 6.3% D18Y (GAT→TAT)  ydjL ← putative Zn‑dependent NAD(P)‑binding oxidoreductase
RA 1,862,404 G→T 37.5% E414* (GAA→TAA)  yeaG → protein kinase, endogenous substrate unidentified; autokinase
RA 1,864,752 C→A 23.2% S37R (AGC→AGA yeaI → putative membrane‑anchored diguanylate cyclase
RA 1,865,422 C→A 100% R261R (CGA→AGA)  yeaI → putative membrane‑anchored diguanylate cyclase
RA 1,868,749 A→C 7.1% E47D (GAA→GAC yeaL → UPF0756 family putative inner membrane protein
RA 1,872,520 G→T 100% P183P (CCG→CCT yeaP → diguanylate cyclase
RA 1,872,542 A→T 5.4% N191Y (AAT→TAT)  yeaP → diguanylate cyclase
RA 1,873,569 C→A 7.0% intergenic (‑57/+91) yeaQ ← / ← yoaG UPF0410 family protein/uncharacterized protein
RA 1,904,572 C→A 6.2% R14R (CGA→AGA)  yebQ → putative transporter
RA 1,909,063 A→C 5.4% F4C (TTT→TGT)  prc ← carboxy‑terminal protease for penicillin‑binding protein 3
RA 1,909,342 T→A 100% E150D (GAA→GAT proQ ← RNA chaperone, putative ProP translation regulator
RA 1,929,069 A→G 32.0% intergenic (‑208/+27) edd ← / ← zwf 6‑phosphogluconate dehydratase/glucose‑6‑phosphate 1‑dehydrogenase
RA 1,932,672 A→T 6.8% E256V (GAA→GTA)  pykA → pyruvate kinase II
RA 1,934,464 C→A 36.7% intergenic (‑14/+106) lpxM ← / ← mepM myristoyl‑acyl carrier protein (ACP)‑dependent acyltransferase/murein DD‑endopeptidase, space‑maker hydrolase, septation protein
RA 1,937,083 A→T 15.8% T55T (ACA→ACT znuC → zinc transporter subunit: ATP‑binding component of ABC superfamily
RA 1,942,066 G→T 31.5% H115N (CAT→AAT)  yebC ← UPF0082 family protein
RA 1,943,414 C→A 5.2% D456Y (GAT→TAT)  aspS ← aspartyl‑tRNA synthetase
RA 1,944,177 C→A 100% L201L (CTG→CTT aspS ← aspartyl‑tRNA synthetase
RA 1,946,006 G→T 49.2% D119Y (GAT→TAT)  yecE → UPF0759 family protein
RA 1,948,050 C→A 30.8% L118I (CTT→ATT)  cmoB → tRNA (cmo5U34)‑carboxymethyltransferase, carboxy‑SAM‑dependent
RA 1,959,915 C→A 57.4% P178P (CCG→CCT flhB ← flagellin export apparatus, substrate specificity protein
RA 1,963,108 C→A 6.6% E172* (GAG→TAG)  cheR ← chemotaxis regulator, protein‑glutamate methyltransferase
RA 1,967,264 C→A 5.9% L111F (TTG→TTT cheW ← purine‑binding chemotaxis protein
RA 1,969,291 G→T 100% I97I (ATC→ATA cheA ← fused chemotactic sensory histidine kinase in two‑component regulatory system with CheB and CheY: sensory histidine kinase/signal sensing protein
RA 1,973,690 A→G 5.0% A468A (GCT→GCC otsA ← trehalose‑6‑phosphate synthase
RA 1,978,094 C→T 10.5% E153K (GAA→AAA)  araG ← fused L‑arabinose transporter subunits of ABC superfamily: ATP‑binding components
RA 1,984,478 G→T 47.8% P208Q (CCG→CAG)  yecA ← UPF0149 family protein
RA 1,984,987 C→A 55.1% T38T (ACG→ACT yecA ← UPF0149 family protein
RA 1,986,289 T→A 100% N4Y (AAT→TAT)  pgsA ← phosphatidylglycerophosphate synthetase
RA 1,991,843 G→A 9.2% L40F (CTC→TTC)  yecS ← ABC family putative inner membrane permease
RA 1,997,314 G→T 100% intergenic (‑227/‑39) fliC ← / → fliD flagellar filament structural protein (flagellin)/flagellar filament capping protein
RA 1,999,632 G→T 100% intergenic (+73/‑5) fliT → / → amyA putative flagellar synthesis and assembly chaperone/cytoplasmic alpha‑amylase
RA 2,007,547 C→A 41.5% R280S (CGC→AGC)  fliF → flagellar basal‑body MS‑ring and collar protein
RA 2,015,451 T→A 43.7% G34G (GGT→GGA fliP → flagellar biosynthesis protein
RA 2,018,405 G→T 11.0% intergenic (‑101/‑62) dsrB ← / → yodD uncharacterized protein/uncharacterized protein
RA 2,018,422 T→A 39.7% intergenic (‑118/‑45) dsrB ← / → yodD uncharacterized protein/uncharacterized protein
RA 2,020,166 C→A 100% D445Y (GAC→TAC)  yedQ ← putative membrane‑anchored diguanylate cyclase
RA 2,034,060 G→T 37.7% G33C (GGT→TGT)  yedZ → inner membrane heme subunit for periplasmic YedYZ reductase
RA 2,035,090 C→A 92.2% Q79K (CAG→AAG)  zinT → zinc and cadmium binding protein, periplasmic
RA 2,040,800 C→A 37.1% T794T (ACC→ACA yeeJ → putative adhesin
RA 2,043,389 G→T 7.5% L1657F (TTG→TTT yeeJ → putative adhesin
RA 2,046,371 A→T 10.6% pseudogene (439/1053 nt) yeeL ← pseudogene, glycosyltransferase homology
RA 2,050,363 G→A 9.6% V9I (GTT→ATT)  yeeN → UPF0082 family protein
RA 2,050,864 G→T 5.0% D176Y (GAC→TAC)  yeeN → UPF0082 family protein
RA 2,060,661 T→A 38.0% N48Y (AAC→TAC)  insH1 ← IS5 transposase and trans‑activator
RA 2,061,545 C→A 41.5% intergenic (‑172/+197) yoeG ← / ← yoeH pseudogene, CP4‑44 putative prophage remnant;Phage or Prophage Related/pseudogene, CP4‑44 putative prophage remnant;Phage or Prophage Related
RA 2,068,098 G→T 35.1% E1027* (GAA→TAA)  flu → CP4‑44 prophage; antigen 43 (Ag43) phase‑variable biofilm formation autotransporter
RA 2,074,680 A→T 100% W22R (TGG→AGG)  sbmC ← DNA gyrase inhibitor
RA 2,075,255 T→A 5.7% V258V (GTA→GTT dacD ← D‑alanyl‑D‑alanine carboxypeptidase (penicillin‑binding protein 6b)
RA 2,077,212 A→T 51.9% N326Y (AAT→TAT)  sbcB → exodeoxyribonuclease I; exonuclease I
RA 2,078,671 C→A 9.7% A112A (GCG→GCT yeeE ← UPF0394 family inner membrane protein
RA 2,082,619 C→T 42.2% intergenic (‑10/+73) yeeZ ← / ← yoeB putative epimerase/toxin of the YoeB‑YefM toxin‑antitoxin system
RA 2,096,834 C→A 6.0% pseudogene (37/446 nt) wbbL ← lipopolysaccharide biosynthesis protein, N‑ter fragment (pseudogene)
RA 2,098,995 C→A 100% G182* (GGA→TGA)  wbbI ← d‑Galf:alpha‑d‑Glc beta‑1,6‑galactofuranosyltransferase
RA 2,102,786 C→T 44.0% V94I (GTT→ATT)  wzxB ← putative polisoprenol‑linked O‑antigen transporter
RA 2,102,969 G→A 7.0% L33F (CTT→TTT)  wzxB ← putative polisoprenol‑linked O‑antigen transporter
RA 2,108,219:1 +A 100% coding (1159/1395 nt) wcaM ← colanic acid biosynthesis protein
RA 2,110,346 G→A 55.8% T88I (ACC→ATC)  wcaL ← putative glycosyl transferase
RA 2,111,376 C→A 7.1% A170A (GCG→GCT wcaK ← colanic acid biosynthesis protein
RA 2,114,414 C→A 5.3% V208F (GTC→TTC)  wcaJ ← colanic biosynthesis UDP‑glucose lipid carrier transferase
RA 2,114,911 A→T 100% L42Q (CTG→CAG)  wcaJ ← colanic biosynthesis UDP‑glucose lipid carrier transferase
RA 2,115,361 C→A 42.7% R367L (CGC→CTC)  cpsG ← phosphomannomutase
RA 2,121,234 C→A 36.1% E188* (GAA→TAA)  gmd ← GDP‑D‑mannose dehydratase, NAD(P)‑binding
RA 2,122,216 C→A 7.6% A52S (GCA→TCA)  wcaF ← putative acyl transferase
RA 2,130,684 G→T 6.4% S14* (TCA→TAA)  wza ← colanic acid export protein; outer membrane auxillary lipoprotein
RA 2,135,016 C→A 6.9% V26V (GTG→GTT asmA ← suppressor of OmpF assembly mutants; putative outer membrane protein assembly factor; inner membrane‑anchored periplasmic protein
RA 2,135,194 A→T 12.8% V168E (GTG→GAG)  dcd ← 2'‑deoxycytidine 5'‑triphosphate deaminase
RA 2,135,719 C→A 9.2% intergenic (‑23/+69) dcd ← / ← udk 2'‑deoxycytidine 5'‑triphosphate deaminase/uridine/cytidine kinase
RA 2,139,450 G→T 17.8% E902* (GAG→TAG)  yegE → putative diguanylate cyclase
RA 2,139,910 G→T 100% R1055L (CGA→CTA)  yegE → putative diguanylate cyclase
RA 2,144,474 C→A 100% intergenic (‑8/‑192) yegI ← / → yegJ protein kinase‑related putative non‑specific DNA‑binding protein/uncharacterized protein
RA 2,148,615 C→A 39.9% R373R (CGC→CGA mdtA → multidrug efflux system, subunit A
RA 2,149,603 A→T 100% E287V (GAA→GTA)  mdtB → multidrug efflux system, subunit B
RA 2,155,768 T→C 44.9% I275T (ATT→ACT)  mdtD → putative arabinose efflux transporter
RA 2,162,105 T→A 11.3% intergenic (‑318/‑88) yegR ← / → yegS uncharacterized protein/phosphatidylglycerol kinase, metal‑dependent
RA 2,163,087 C→A 33.0% R299S (CGT→AGT)  yegS → phosphatidylglycerol kinase, metal‑dependent
RA 2,168,487 A→T 38.5% D14E (GAT→GAA gatA ← galactitol‑specific enzyme IIA component of PTS
RA 2,168,795 C→A 100% D336Y (GAT→TAT)  gatZ ← D‑tagatose 1,6‑bisphosphate aldolase 2, subunit
RA 2,179,205 G→T 100% A24E (GCG→GAG)  rcnR ← transcriptional repressor of rcnA
RA 2,181,645 A→G 93.1% N83N (AAT→AAC yehA ← putative fimbrial‑like adhesin protein
RA 2,191,496 C→A 37.0% pseudogene (1544/2847 nt) yehH → DUF4132 family pseudogene; defective yehI paralog; molybdate metabolism regulator, first fragment; molybdate metabolism regulator, second fragment 2; yehI' molR mutations have phenotypes and the N‑terminal molR fragment of yehI' may be expressed and may have retained or evolved MolR function
RA 2,194,695 T→A 100% L313Q (CTA→CAA)  yehI → DUF4132 domain‑containing protein
RA 2,195,449 A→T 100% E564D (GAA→GAT yehI → DUF4132 domain‑containing protein
RA 2,197,797 A→T 31.9% intergenic (+29/‑278) yehK → / → yehL uncharacterized protein/putative ABC superfamily transporter ATP‑binding subunit
RA 2,208,664 G→T 9.5% R107L (CGC→CTC)  mlrA → transcriptional activator of csgD and csgBA
RA 2,209,162 C→A 60.1% I9I (ATC→ATA yohO → putative membrane protein
RA 2,216,296 C→A 100% I211I (ATC→ATA dld → D‑lactate dehydrogenase, FAD‑binding, NADH independent
RA 2,220,503 C→T 34.9% V83M (GTG→ATG)  yohF ← putative oxidoreductase
RA 2,223,247 C→T 58.9% W206* (TGG→TGA dusC ← tRNA‑dihydrouridine synthase C
RA 2,224,396 T→A 29.7% V98V (GTT→GTA yohJ → UPF0299 family inner membrane protein
RA 2,225,190 C→T 100% G231G (GGC→GGT yohK → LrgB family inner membrane protein
RA 2,235,258 G→A 11.5% intergenic (‑111/+31) galS ← / ← yeiB galactose‑ and fucose‑inducible galactose regulon transcriptional isorepressor; mgl operon transcriptional repressor; autorepressor/DUF418 family putative inner membrane protein
RA 2,237,098 G→T 100% H12N (CAT→AAT)  folE ← GTP cyclohydrolase I
RA 2,240,361 C→A 5.4% intergenic (‑113/+181) cirA ← / ← lysP colicin IA outer membrane receptor and translocator; ferric iron‑catecholate transporter/lysine transporter
RA 2,240,937 A→T 6.0% C359S (TGC→AGC)  lysP ← lysine transporter
RA 2,253,140 C→A 12.9% intergenic (‑365/+58) psuK ← / ← fruA pseudouridine kinase/fused fructose‑specific PTS enzymes: IIBcomponent/IIC components
RA 2,263,137 C→A 54.9% intergenic (+91/‑321) lpxT → / → mepS lipid A 1‑diphosphate synthase; undecaprenyl pyrophosphate:lipid A 1‑phosphate phosphotransferase/murein DD‑endopeptidase, space‑maker hydrolase, mutational suppressor of prc thermosensitivity, outer membrane lipoprotein
RA 2,264,143 G→A 100% intergenic (+119/‑62) mepS → / → rtn murein DD‑endopeptidase, space‑maker hydrolase, mutational suppressor of prc thermosensitivity, outer membrane lipoprotein/resistance protein for phages lambda and N4, putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 2,270,338 T→A 39.1% L187Q (CTG→CAG)  yejF → microcin C transporter, ATP‑binding subunit; ABC family
RA 2,281,503 C→A 5.8% pseudogene (891/2525 nt) yejO ← pseudogene, autotransporter outer membrane homology;putative transport; Not classified; putative ATP‑binding component of a transport system
RA 2,287,829 C→A 52.6% S185S (TCG→TCT ccmF ← heme lyase, CcmF subunit
RA 2,289,043 C→A 55.6% W8L (TGG→TTG)  ccmD ← cytochrome c biogenesis protein
RA 2,289,374 C→A 100% V142V (GTG→GTT ccmC ← heme exporter subunit
RA 2,303,070 T→G 100% Q272P (CAG→CCG)  ada ← fused DNA‑binding transcriptional dual regulator/O6‑methylguanine‑DNA methyltransferase
RA 2,303,607 A→C 48.1% L93R (CTG→CGG)  ada ← fused DNA‑binding transcriptional dual regulator/O6‑methylguanine‑DNA methyltransferase
RA 2,305,116 C→A 100% intergenic (‑103/+9) apbE ← / ← ompC putative thiamine‑synthetic flavin transferase lipoprotein/outer membrane porin protein C
RA 2,305,135 T→C 100% Y365C (TAC→TGC)  ompC ← outer membrane porin protein C
RA 2,306,671 C→T 6.5% intergenic (+16/‑296) micF → / → rcsD sRNA antisense regulator affecting ompF expression, Hfq‑dependent/phosphotransfer intermediate protein in two‑component regulatory system with RcsBC
RA 2,310,213 G→T 56.5% K186N (AAG→AAT rcsB → response regulator in two‑component regulatory system with RcsC and YojN
RA 2,311,008 T→A 9.2% H783L (CAC→CTC)  rcsC ← hybrid sensory kinase in two‑component regulatory system with RcsB and YojN
RA 2,312,708 C→A 6.6% A216A (GCG→GCT rcsC ← hybrid sensory kinase in two‑component regulatory system with RcsB and YojN
RA 2,313,924 C→A 34.0% R135S (CGC→AGC)  atoS → sensory histidine kinase in two‑component regulatory system with AtoC
RA 2,319,204 G→T 7.8% G324C (GGT→TGT)  atoE → short chain fatty acid transporter
RA 2,330,502 C→A 100% D800Y (GAT→TAT)  gyrA ← DNA gyrase (type II topoisomerase), subunit A
RA 2,331,288 C→T 25.2% D538N (GAT→AAT)  gyrA ← DNA gyrase (type II topoisomerase), subunit A
RA 2,341,217 C→A 35.2% H119N (CAT→AAT)  nrdB → ribonucleoside‑diphosphate reductase 1, beta subunit, ferritin‑like protein
RA 2,344,807 G→T 5.4% V349V (GTC→GTA glpT ← sn‑glycerol‑3‑phosphate transporter
RA 2,346,906 G→T 13.7% D261Y (GAT→TAT)  glpA → sn‑glycerol‑3‑phosphate dehydrogenase (anaerobic), large subunit, FAD/NAD(P)‑binding
RA 2,348,894 T→A 54.7% V384E (GTG→GAG)  glpB → sn‑glycerol‑3‑phosphate dehydrogenase (anaerobic), membrane anchor subunit
RA 2,352,573 C→A 100% P353P (CCG→CCT rhmT ← putative L‑rhamnonate transporter
RA 2,353,889 C→A 34.0% V335V (GTG→GTT rhmD ← L‑rhamnonate dehydratase
RA 2,359,673 G→T 100% M89I (ATG→ATT arnB → uridine 5'‑(beta‑1‑threo‑pentapyranosyl‑4‑ulose diphosphate) aminotransferase, PLP‑dependent
RA 2,362,338 T→A 100% L274Q (CTG→CAG)  arnA → fused UDP‑L‑Ara4N formyltransferase/UDP‑GlcA C‑4'‑decarboxylase
RA 2,366,555 T→G 6.3% F62C (TTT→TGT)  arnF → undecaprenyl phosphate‑alpha‑L‑ara4N exporter; flippase ArnEF subunit
RA 2,370,361:1 +G 100% coding (711/759 nt) menH ← 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase
RA 2,370,837 Δ1 bp 40.8% coding (235/759 nt) menH ← 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase
RA 2,370,987 C→A 100% E29* (GAA→TAA)  menH ← 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase
RA 2,373,129 C→A 7.2% D332Y (GAT→TAT)  menF ← isochorismate synthase 2
RA 2,380,078 C→T 54.2% S247F (TCT→TTT)  yfbL → putative peptidase
RA 2,383,897 C→A 59.0% R363L (CGC→CTC)  nuoN ← NADH:ubiquinone oxidoreductase, membrane subunit N
RA 2,399,210 G→T 100% S304* (TCA→TAA)  lrhA ← transcriptional repressor of flagellar, motility and chemotaxis genes
RA 2,400,861 G→A 8.0% intergenic (‑741/‑179) lrhA ← / → alaA transcriptional repressor of flagellar, motility and chemotaxis genes/valine‑pyruvate aminotransferase 2
RA 2,405,946 T→G 100% Q43P (CAG→CCG)  yfbU ← UPF0304 family protein
RA 2,407,678 T→A 38.1% S244T (TCT→ACT)  ackA → acetate kinase A and propionate kinase 2
RA 2,412,205 C→A 56.4% D151Y (GAT→TAT)  yfcD ← putative NUDIX hydrolase
RA 2,415,498 G→T 37.4% T104T (ACG→ACT yfcH → putative NAD‑dependent nucleotide‑sugar epimerase
RA 2,416,101 C→A 100% intergenic (+21/+27) yfcH → / ← yfcI putative NAD‑dependent nucleotide‑sugar epimerase/transposase_31 family protein
RA 2,422,841 C→A 100% D293Y (GAT→TAT)  purF ← amidophosphoribosyltransferase
RA 2,423,034 G→T 46.7% G228G (GGC→GGA purF ← amidophosphoribosyltransferase
RA 2,424,074 C→T 100% D57N (GAC→AAC)  cvpA ← colicin V production membrane protein
RA 2,425,016 G→T 5.1% R50S (CGT→AGT)  dedD ← membrane‑anchored periplasmic protein involved in septation
RA 2,425,587 C→A 14.5% D279Y (GAC→TAC)  folC ← bifunctional folylpolyglutamate synthase/ dihydrofolate synthase
RA 2,426,731 G→T 33.7% I225I (ATC→ATA accD ← acetyl‑CoA carboxylase, beta (carboxyltransferase) subunit
RA 2,434,701 C→A 5.4% A128A (GCG→GCT fabB ← 3‑oxoacyl‑[acyl‑carrier‑protein] synthase I
RA 2,442,770 A→C 40.5% D253E (GAT→GAG yfcO ← DUF2544 family putative outer membrane protein
RA 2,442,790 C→A 37.6% D247Y (GAT→TAT)  yfcO ← DUF2544 family putative outer membrane protein
RA 2,444,107 T→G 50.2% N150H (AAT→CAT)  yfcQ ← putative fimbrial‑like adhesin protein
RA 2,450,335 C→T 100% intergenic (‑44/+159) sixA ← / ← fadJ phosphohistidine phosphatase/fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase
RA 2,450,346 G→T 100% intergenic (‑55/+148) sixA ← / ← fadJ phosphohistidine phosphatase/fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase
RA 2,452,454 G→T 100% P62Q (CCG→CAG)  fadJ ← fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase
RA 2,453,358 G→T 7.4% I197I (ATC→ATA fadI ← beta‑ketoacyl‑CoA thiolase, anaerobic, subunit
RA 2,454,297 T→G 100% E39D (GAA→GAC yfcZ ← UPF0381 family protein
RA 2,456,282 C→A 45.9% intergenic (+157/‑209) fadL → / → yfdF long‑chain fatty acid outer membrane transporter/uncharacterized protein
RA 2,463,910 G→T 10.2% R434I (AGA→ATA)  gtrS → serotype‑specific glucosyl transferase, CPS‑53 (KpLE1) prophage
RA 2,463,920 C→A 5.4% D437E (GAC→GAA gtrS → serotype‑specific glucosyl transferase, CPS‑53 (KpLE1) prophage
RA 2,466,183 G→T 12.9% H60N (CAT→AAT)  yfdN ← CPS‑53 (KpLE1) prophage; uncharacterized protein
RA 2,472,897 A→T 47.9% T73S (ACT→TCT)  dsdA → D‑serine dehydratase
RA 2,474,418 G→T 100% S413* (TCA→TAA)  emrY ← putative multidrug efflux system
RA 2,475,340 G→T 7.1% L106I (CTT→ATT)  emrY ← putative multidrug efflux system
RA 2,494,310 C→A 5.9% T150K (ACG→AAG)  ypdB → response regulator activating yhjX; pyruvate‑responsive YpdAB two‑component system
RA 2,495,918 C→A 38.4% V683F (GTT→TTT)  fryA ← putative PTS enzyme, Hpr component/enzyme I component/enzyme IIA component
RA 2,503,015 C→A 39.9% intergenic (‑110/‑94) glk ← / → yfeO glucokinase/putative ion channel protein
RA 2,503,813 A→C 5.0% A235A (GCA→GCC yfeO → putative ion channel protein
RA 2,504,065 C→T 38.7% G319G (GGC→GGT yfeO → putative ion channel protein
RA 2,505,337 T→A 29.0% L283F (TTA→TTT mntH ← manganese/divalent cation transporter
RA 2,514,152 G→T 5.4% intergenic (‑1/‑258) gltX ← / → valU glutamyl‑tRNA synthetase/tRNA‑Val
RA 2,520,652 C→A 100% I116I (ATC→ATA yfeH → putative inorganic ion transporter
RA 2,522,624 C→A 38.1% A304A (GCG→GCT ligA ← DNA ligase, NAD(+)‑dependent
RA 2,526,583 C→A 9.9% I272I (ATC→ATA cysK → cysteine synthase A, O‑acetylserine sulfhydrolase A subunit
RA 2,541,934 C→A 9.5% S158R (AGC→AGA yfeW → penicillin binding protein PBP4B; weak DD‑carboxypeptidase activity
RA 2,542,627 T→G 58.3% I389M (ATT→ATG yfeW → penicillin binding protein PBP4B; weak DD‑carboxypeptidase activity
RA 2,545,086 C→A 42.6% D138Y (GAT→TAT)  ypeA ← putative acyl‑CoA transferase
RA 2,549,676 C→A 100% L28L (CTG→CTT eutL ← putative ethanol utilization carboxysome structural protein
RA 2,561,221 C→A 52.0% P82P (CCG→CCT eutH ← ethanolamine transporter
RA 2,563,208 C→A 5.6% A163A (GCG→GCT eutJ ← ethanolamine utilization protein, HSP70/actin superfamily protein
RA 2,568,720 C→T 100% A33T (GCC→ACC)  eutP ← putative P‑loop NTPase ethanolamine utilization protein
RA 2,576,325 C→A 100% E171D (GAG→GAT nudK ← GDP‑mannose pyrophosphatase
RA 2,586,791 G→T 39.7% G113G (GGC→GGA ypfH ← palmitoyl‑CoA esterase activity, uncertain physiological substrate
RA 2,587,029:1 +G 100% coding (101/699 nt) ypfH ← palmitoyl‑CoA esterase activity, uncertain physiological substrate
RA 2,589,933 G→A 100% T55I (ACC→ATC)  ypfJ ← putative neutral zinc metallopeptidase
RA 2,596,912 C→A 10.4% S579* (TCA→TAA)  hyfB → hydrogenase 4, membrane subunit
RA 2,597,173 T→G 58.2% L666R (CTG→CGG)  hyfB → hydrogenase 4, membrane subunit
RA 2,603,728 A→C 46.3% Q69P (CAG→CCG)  hyfH → hydrogenase 4, Fe‑S subunit
RA 2,606,516 G→T 100% D420Y (GAC→TAC)  hyfR → hydrogenase‑4 transcriptional activator
RA 2,610,919 C→A 100% intergenic (+3/‑18) bepA → / → yfgD periplasmic metalloprotease and chaperone for OM protein maintenance and assembly/putative oxidoreductase
RA 2,611,391 T→A 33.6% intergenic (+95/+43) yfgD → / ← hda putative oxidoreductase/ATPase regulatory factor involved in DnaA inactivation
RA 2,612,335 C→A 14.5% A395A (GCG→GCT uraA ← uracil permease
RA 2,614,168 C→A 100% D22Y (GAT→TAT)  upp ← uracil phosphoribosyltransferase
RA 2,615,370 C→A 41.7% S272Y (TCT→TAT)  purM → phosphoribosylaminoimidazole synthetase
RA 2,617,515 T→G 25.0% I371M (ATT→ATG ppk → polyphosphate kinase, component of RNA degradosome
RA 2,618,693 G→T 54.3% E74* (GAA→TAA)  ppx → exopolyphosphatase
RA 2,619,125 G→T 40.9% G218C (GGT→TGT)  ppx → exopolyphosphatase
RA 2,632,012 C→A 54.8% intergenic (‑1/+10) bamB ← / ← yfgM BamABCDE complex OM biogenesis lipoprotein/putative anti‑RcsB factor
RA 2,651,665 G→T 100% G210G (GGC→GGA hscA ← DnaK‑like molecular chaperone specific for IscU
RA 2,653,259 C→A 8.4% intergenic (‑14/+3) iscA ← / ← iscU FeS cluster assembly protein/iron‑sulfur cluster assembly scaffold protein
RA 2,654,383 A→T 9.4% C170S (TGC→AGC)  iscS ← cysteine desulfurase (tRNA sulfurtransferase), PLP‑dependent
RA 2,658,679 G→T 47.8% intergenic (+76/‑115) yfhR → / → csiE putative S9 family prolyl oligopeptidase/stationary phase inducible protein
RA 2,664,115 C→A 26.4% R123R (CGG→AGG)  hcaF → 3‑phenylpropionate dioxygenase, small (beta) subunit
RA 2,668,994 C→A 35.0% D43Y (GAT→TAT)  yphC ← putative Zn‑dependent NAD(P)‑binding oxidoreductase
RA 2,669,191 G→T 10.2% R332S (CGC→AGC)  yphD ← inner membrane putative ABC superfamily sugar transporter permease
RA 2,669,978 C→A 48.3% A69A (GCG→GCT yphD ← inner membrane putative ABC superfamily sugar transporter permease
RA 2,671,274 C→A 100% T149T (ACG→ACT yphE ← putative sugar transporter subunit of ABC superfamily, ATP‑binding component
RA 2,678,030 C→A 29.9% A279A (GCG→GCT glyA ← serine hydroxymethyltransferase
RA 2,679,151 C→T 6.8% intergenic (‑285/‑43) glyA ← / → hmp serine hydroxymethyltransferase/fused nitric oxide dioxygenase/dihydropteridine reductase 2
RA 2,681,873 T→A 100% Q97L (CAG→CTG)  glrR ← response regulator regulating glmY sRNA in two‑component system with sensor protein GlrK
RA 2,683,829 C→A 100% R210L (CGT→CTT)  glrK ← sensor protein kinase regulating glmY sRNA in two‑component system with response regulator GlrR
RA 2,688,062 C→A 9.3% D281Y (GAT→TAT)  purL ← phosphoribosylformyl‑glycineamide synthetase
RA 2,692,793 C→A 58.1% H226N (CAT→AAT)  yfhH → putative DNA‑binding transcriptional regulator
RA 2,694,564 G→T 11.2% I175I (ATC→ATA pdxJ ← pyridoxine 5'‑phosphate synthase
RA 2,694,843 G→T 59.6% I82I (ATC→ATA pdxJ ← pyridoxine 5'‑phosphate synthase
RA 2,699,380 C→A 52.0% P368P (CCG→CCT lepA ← back‑translocating elongation factor EF4, GTPase
RA 2,706,575 C→A 7.9% I107I (ATC→ATA srmB → ATP‑dependent RNA helicase
RA 2,711,249 G→T 8.0% G213G (GGC→GGA yfiF ← putative methyltransferase
RA 2,715,643 G→T 100% E778* (GAA→TAA)  pka → protein lysine acetyltransferase
RA 2,719,426 T→C 100% intergenic (‑321/+2) kgtP ← / ← rrfG alpha‑ketoglutarate transporter/5S ribosomal RNA of rrnG operon
RA 2,726,786 C→A 100% A249A (GCG→GCT clpB ← protein disaggregation chaperone
RA 2,730,789 G→T 35.8% E93* (GAA→TAA)  raiA → cold shock protein associated with 30S ribosomal subunit
RA 2,733,108 G→T 5.2% G107G (GGC→GGA tyrA ← fused chorismate mutase T/prephenate dehydrogenase
RA 2,733,627 G→T 5.2% R295S (CGC→AGC)  aroF ← 3‑deoxy‑D‑arabino‑heptulosonate‑7‑phosphate synthase, tyrosine‑repressible
RA 2,733,753 C→T 100% E253K (GAG→AAG)  aroF ← 3‑deoxy‑D‑arabino‑heptulosonate‑7‑phosphate synthase, tyrosine‑repressible
RA 2,735,293 A→T 38.0% I20I (ATA→ATT yfiR → putative periplasmic inhibitor of YfiN activity
RA 2,740,948 C→A 39.7% T69T (ACG→ACT ffh ← Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)
RA 2,740,971 G→T 7.1% H62N (CAT→AAT)  ffh ← Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)
RA 2,761,733 T→A 36.3% V222E (GTA→GAA)  yfjP → CP4‑57 prophage; 50S ribosome‑binding GTPase family protein
RA 2,762,153 C→A 18.2% R44S (CGC→AGC)  yfjQ → CP4‑57 prophage; uncharacterized protein
RA 2,765,545 C→A 6.9% pseudogene (881/900 nt) yfjV ← pseudogene, CP4‑57 prophage;Phage or Prophage Related; putative pump protein
RA 2,771,358 G→A 100% intergenic (+217/+147) ypjF → / ← ypjA CP4‑57 prophage; toxin of the YpjF‑YfjZ toxin‑antitoxin system/adhesin‑like autotransporter
RA 2,778,281 C→T 7.8% pseudogene (90/1374 nt) ypjC ← pseudogene
RA 2,779,067 C→A 100% intergenic (‑697/+54) ypjC ← / ← ileY pseudogene/tRNA‑Ile
RA 2,786,234 G→T 5.8% A47A (GCG→GCT gabT → 4‑aminobutyrate aminotransferase, PLP‑dependent
RA 2,799,737 C→A 39.3% V123V (GTC→GTA proW → glycine betaine transporter subunit
RA 2,799,851 C→A 5.8% V161V (GTC→GTA proW → glycine betaine transporter subunit
RA 2,805,849 T→C 7.8% L355P (CTG→CCG)  emrA → multidrug efflux system
RA 2,808,987 G→T 52.7% S271* (TCG→TAG)  gshA ← glutamate‑cysteine ligase
RA 2,811,405 A→G 5.4% intergenic (‑186/+13) argQ ← / ← argZ tRNA‑Arg/tRNA‑Arg
RA 2,811,408 T→A 8.1% intergenic (‑189/+10) argQ ← / ← argZ tRNA‑Arg/tRNA‑Arg
RA 2,819,102 G→T 44.6% intergenic (‑167/‑89) mltB ← / → srlA membrane‑bound lytic murein transglycosylase B/glucitol/sorbitol‑specific enzyme IIC component of PTS
RA 2,825,783 C→T 100% intergenic (‑135/‑52) norR ← / → norV anaerobic nitric oxide reductase DNA‑binding transcriptional activator/anaerobic nitric oxide reductase flavorubredoxin
RA 2,828,952 C→A 100% T611T (ACG→ACT hypF ← carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases
RA 2,831,086 C→A 51.1% E127* (GAA→TAA)  hydN ← formate dehydrogenase‑H, [4Fe‑4S] ferredoxin subunit
RA 2,831,465 C→A 6.8% intergenic (‑1/+148) hydN ← / ← ascG formate dehydrogenase‑H, [4Fe‑4S] ferredoxin subunit/asc operon transcriptional repressor; prpBC operon repressor
RA 2,835,094 C→A 57.3% P249Q (CCG→CAG)  ascB → cryptic 6‑phospho‑beta‑glucosidase
RA 2,835,894 C→A 5.7% intergenic (+121/+38) ascB → / ← hycI cryptic 6‑phospho‑beta‑glucosidase/protease involved in processing C‑terminal end of HycE
RA 2,837,370 C→A 8.4% R67L (CGA→CTA)  hycG ← hydrogenase 3 and formate hydrogenase complex, HycG subunit
RA 2,837,725 C→A 10.8% E129D (GAG→GAT hycF ← formate hydrogenlyase complex iron‑sulfur protein
RA 2,841,044 C→A 93.8% A519A (GCG→GCT hycC ← hydrogenase 3, membrane subunit
RA 2,842,289 C→T 9.4% V104V (GTG→GTA hycC ← hydrogenase 3, membrane subunit
RA 2,846,112 C→A 54.6% I206I (ATC→ATA hypD → hydrogenase maturation protein
RA 2,847,161 C→A 7.3% I183I (ATC→ATA hypE → carbamoyl dehydratase, hydrogenases 1,2,3 maturation protein
RA 2,848,487 G→T 5.6% R264L (CGC→CTC)  fhlA → formate hydrogenlyase transcriptional activator
RA 2,850,790 C→A 100% I113I (ATC→ATA mutS → methyl‑directed mismatch repair protein
RA 2,854,711 G→A 9.5% intergenic (‑118/‑78) ygbI ← / → ygbJ DeoR family putative transcriptional regulator/putative dehydrogenase
RA 2,854,737:1 +T 6.9% intergenic (‑144/‑52) ygbI ← / → ygbJ DeoR family putative transcriptional regulator/putative dehydrogenase
RA 2,860,460 G→T 7.3% R151S (CGC→AGC)  rpoS ← RNA polymerase, sigma S (sigma 38) factor
RA 2,871,140 C→A 7.7% intergenic (+163/+788) iap → / ← ygbF aminopeptidase in alkaline phosphatase isozyme conversion/CRISPR adaptation ssRNA endonuclease
RA 2,873,087 G→T 100% V15V (GTC→GTA ygbT ← multifunctional endonuclease Cas1, CRISPR adaptation protein; DNA repair enzyme
RA 2,876,760 C→T 100% G246G (GGG→GGA casA ← CRISP RNA (crRNA) containing Cascade antiviral complex protein
RA 2,878,668 G→T 100% V637V (GTC→GTA ygcB ← R‑loop helicase‑annealase Cas3 needed for Cascade anti‑viral activity
RA 2,879,449 G→T 100% S377* (TCA→TAA)  ygcB ← R‑loop helicase‑annealase Cas3 needed for Cascade anti‑viral activity
RA 2,888,584 G→T 100% I185I (ATC→ATA ygcQ ← putative flavoprotein
RA 2,890,009 C→A 5.9% A407A (GCG→GCT ygcS ← putative transporter
RA 2,893,446 T→A 52.8% K63* (AAA→TAA)  ygcW ← putative dehydrogenase
RA 2,895,997 C→A 32.0% A248E (GCG→GAG)  ygcE → putative kinase
RA 2,896,310 C→A 34.3% S352R (AGC→AGA ygcE → putative kinase
RA 2,920,080 C→A 5.7% N138K (AAC→AAA ygdH → UPF0717 family protein
RA 2,927,355 A→C 6.1% intergenic (‑308/‑239) fucA ← / → fucP L‑fuculose‑1‑phosphate aldolase/L‑fucose transporter
RA 2,931,717 C→A 100% N307K (AAC→AAA fucK → L‑fuculokinase
RA 2,932,832 C→A 37.9% R36S (CGT→AGT)  fucR → l‑fucose operon activator
RA 2,932,835 C→T 59.7% R37C (CGC→TGC)  fucR → l‑fucose operon activator
RA 2,934,843 G→T 100% H50N (CAT→AAT)  ygdD ← UPF0382 family inner membrane protein
RA 2,936,686 G→T 36.9% intergenic (‑182/‑10) ygdI ← / → csdA DUF903 family verified lipoprotein/cysteine sulfinate desulfinase
RA 2,938,640 C→A 37.8% D188Y (GAT→TAT)  tcdA ← tRNA threonylcarbamoyladenosine dehydratase; sulfur acceptor for CsdA
RA 2,957,480 C→A 36.9% L19F (TTG→TTT ppdA ← putative prepilin peptidase‑dependent protein
RA 2,959,004 G→A 100% I131I (ATC→ATT lgt ← phosphatidylglycerol‑prolipoprotein diacylglyceryl transferase
RA 2,960,713 Δ1 bp 35.8% coding (1081/2247 nt) ptsP ← fused PTS enzyme: PEP‑protein phosphotransferase (enzyme I)/GAF domain containing protein
RA 2,962,962 T→A 57.7% intergenic (‑626/‑59) rppH ← / → mutH RNA pyrophosphohydrolase/methyl‑directed mismatch repair protein
RA 2,967,572 A→G 36.8% F601S (TTT→TCT)  aas ← fused 2‑acylglycerophospho‑ethanolamine acyl transferase/acyl‑acyl carrier protein synthetase
RA 2,969,887 C→A 8.7% intergenic (‑143/‑71) omrB ← / → galR sRNA antisense regulator downregulates OM proteins and curli; positively regulated by OmpR/EnvZ, Hfq‑dependent/galactose‑inducible d‑galactose regulon transcriptional repressor; autorepressor
RA 2,978,850 C→A 42.1% V34V (GTG→GTT yqeF ← short chain acyltransferase
RA 2,979,127 C→T 14.3% intergenic (‑176/‑79) yqeF ← / → yqeG short chain acyltransferase/putative transporter
RA 2,983,700 T→G 7.8% Q7P (CAG→CCG)  yqeK ← uncharacterized protein
RA 2,985,884 C→T 55.6% I144I (ATC→ATT ygeH → putative transcriptional regulator
RA 2,987,787 C→A 6.8% pseudogene (47/60 nt) pbl → pseudogene, peptidoglycan‑binding enzyme family
RA 2,987,928 C→A 5.8% pseudogene (524/633 nt) ygeK ← pseudogene; putative 2‑component transcriptional regulator
RA 2,988,554 G→A 52.9% intergenic (‑103/+119) ygeK ← / ← ygeN pseudogene; putative 2‑component transcriptional regulator/pseudogene
RA 2,988,737 T→G 37.2% pseudogene (383/447 nt) ygeN ← pseudogene
RA 2,989,295 C→A 100% pseudogene (85/261 nt) ygeN ← pseudogene
RA 2,993,211 C→A 100% V14L (GTG→TTG)  ygeR ← LysM domain‑containing M23 family putative peptidase; septation lipoprotein
RA 2,993,699 C→A 100% intergenic (‑449/‑5) ygeR ← / → xdhA LysM domain‑containing M23 family putative peptidase; septation lipoprotein/xanthine dehydrogenase, molybdenum binding subunit
RA 2,995,335 C→A 34.4% V544V (GTC→GTA xdhA → xanthine dehydrogenase, molybdenum binding subunit
RA 3,009,187 G→T 52.3% intergenic (+90/‑232) mocA → / → ygfK CTP:molybdopterin cytidylyltransferase/putative Fe‑S subunit oxidoreductase subunit
RA 3,012,429 A→G 5.4% N1004S (AAC→AGC)  ygfK → putative Fe‑S subunit oxidoreductase subunit
RA 3,016,192 G→T 35.5% M506I (ATG→ATT xdhD → putative hypoxanthine oxidase, molybdopterin‑binding/Fe‑S binding
RA 3,017,285 G→T 100% D871Y (GAC→TAC)  xdhD → putative hypoxanthine oxidase, molybdopterin‑binding/Fe‑S binding
RA 3,017,379 C→A 7.0% P902Q (CCG→CAG)  xdhD → putative hypoxanthine oxidase, molybdopterin‑binding/Fe‑S binding
RA 3,019,203 G→T 41.6% E27* (GAG→TAG)  guaD → guanine deaminase
RA 3,019,343 G→T 36.6% L73L (CTG→CTT guaD → guanine deaminase
RA 3,024,081 A→C 53.3% V70V (GTT→GTG ygfT ← putative oxidoreductase, Fe‑S subunit/nucleotide‑binding subunit
RA 3,024,983 C→G 100% G86G (GGC→GGG uacT → uric acid permease
RA 3,025,678 A→T 41.7% Q318L (CAA→CTA)  uacT → uric acid permease
RA 3,028,224 G→T 5.4% L104I (CTC→ATC)  lysS ← lysine tRNA synthetase, constitutive
RA 3,030,181 G→T 58.8% H429N (CAT→AAT)  recJ ← ssDNA exonuclease, 5' ‑‑> 3'‑specific
RA 3,035,271 G→T 41.7% V200V (GTG→GTT ygfZ → iron‑sulfur cluster repair protein, plumbagin resistance
RA 3,036,052 C→A 47.0% S152S (TCG→TCT yqfA ← hemolysin III family HylIII inner membrane protein
RA 3,041,026 C→A 6.8% D459Y (GAC→TAC)  gcvP ← glycine decarboxylase, PLP‑dependent, subunit (protein P) of glycine cleavage complex
RA 3,043,625 G→A 5.7% I134I (ATC→ATT gcvT ← aminomethyltransferase, tetrahydrofolate‑dependent, subunit (T protein) of glycine cleavage complex
RA 3,044,281 G→A 34.6% intergenic (‑255/+193) gcvT ← / ← ubiI aminomethyltransferase, tetrahydrofolate‑dependent, subunit (T protein) of glycine cleavage complex/2‑octaprenylphenol hydroxylase, FAD‑dependent
RA 3,044,437 T→A 41.7% intergenic (‑411/+37) gcvT ← / ← ubiI aminomethyltransferase, tetrahydrofolate‑dependent, subunit (T protein) of glycine cleavage complex/2‑octaprenylphenol hydroxylase, FAD‑dependent
RA 3,044,464 G→A 100% intergenic (‑438/+10) gcvT ← / ← ubiI aminomethyltransferase, tetrahydrofolate‑dependent, subunit (T protein) of glycine cleavage complex/2‑octaprenylphenol hydroxylase, FAD‑dependent
RA 3,046,473 G→T 30.7% N135K (AAC→AAA ubiH ← 2‑octaprenyl‑6‑methoxyphenol hydroxylase, FAD/NAD(P)‑binding
RA 3,047,237 G→T 6.8% I321I (ATC→ATA pepP ← proline aminopeptidase P II
RA 3,049,645 G→A 33.6% E16K (GAA→AAA)  fau → 5‑formyltetrahydrofolate cyclo‑ligase family protein
RA 3,051,943 A→G 5.7% intergenic (‑174/+82) serA ← / ← rpiA D‑3‑phosphoglycerate dehydrogenase/ribose 5‑phosphate isomerase, constitutive
RA 3,051,973 C→T 5.8% intergenic (‑204/+52) serA ← / ← rpiA D‑3‑phosphoglycerate dehydrogenase/ribose 5‑phosphate isomerase, constitutive
RA 3,055,069 C→A 35.5% V287V (GTC→GTA scpA → methylmalonyl‑CoA mutase
RA 3,055,407 C→T 10.6% S400L (TCG→TTG)  scpA → methylmalonyl‑CoA mutase
RA 3,056,567 T→A 9.3% F74L (TTT→TTA argK → membrane ATPase/protein kinase
RA 3,058,692 C→T 41.1% P178S (CCT→TCT)  scpC → propionyl‑CoA:succinate CoA transferase
RA 3,058,769 C→T 55.7% I203I (ATC→ATT scpC → propionyl‑CoA:succinate CoA transferase
RA 3,064,914 G→T 92.5% I356I (ATC→ATA pgk ← phosphoglycerate kinase
RA 3,068,135 G→T 42.2% F140L (TTC→TTA yggD ← MtlR family putative transcriptional repressor
RA 3,068,854 C→A 42.5% E230* (GAG→TAG)  yggF ← fructose 1,6 bisphosphatase isozyme
RA 3,074,352 C→T 36.6% D215N (GAC→AAC)  tktA ← transketolase 1, thiamine triphosphate‑binding
RA 3,074,868 C→A 5.6% D43Y (GAT→TAT)  tktA ← transketolase 1, thiamine triphosphate‑binding
RA 3,075,114 C→A 100% intergenic (‑120/‑158) tktA ← / → loiP transketolase 1, thiamine triphosphate‑binding/Phe‑Phe periplasmic metalloprotease, OM lipoprotein; low salt‑inducible; heat shock protein that binds Era
RA 3,076,526 C→A 100% D211Y (GAC→TAC)  speB ← agmatinase
RA 3,080,098 T→G 38.3% S12A (TCT→GCT)  metK → S‑adenosylmethionine synthetase
RA 3,080,618 T→A 100% V185E (GTG→GAG)  metK → S‑adenosylmethionine synthetase
RA 3,080,922 C→A 7.6% I286I (ATC→ATA metK → S‑adenosylmethionine synthetase
RA 3,081,697 T→A 10.1% C19S (TGC→AGC)  galP → D‑galactose transporter
RA 3,088,065 C→A 53.3% V125V (GTG→GTT yggR ← putative PilT family AAA+ ATPase
RA 3,088,235 C→A 43.1% A69S (GCC→TCC)  yggR ← putative PilT family AAA+ ATPase
RA 3,093,737 A→C 31.1% T117T (ACT→ACG ansB ← periplasmic L‑asparaginase 2
RA 3,097,262 C→T 55.9% F297F (TTC→TTT mutY → adenine DNA glycosylase
RA 3,110,751 C→A 100% R574L (CGT→CTT)  yghJ ← DUF4092 family putative lipoprotein peptidase
RA 3,111,434 C→A 100% A346A (GCG→GCT yghJ ← DUF4092 family putative lipoprotein peptidase
RA 3,120,216 C→A 100% D389Y (GAT→TAT)  glcD ← glycolate oxidase subunit, FAD‑linked
RA 3,121,999 G→T 5.5% V123V (GTG→GTT glcC → glycolate‑inducible glc operon transcriptional repressor; autorepressor
RA 3,132,601 T→G 38.3% I172M (ATT→ATG yghU → putative S‑transferase
RA 3,133,918 C→A 5.9% E81* (GAA→TAA)  hybE ← hydrogenase 2‑specific chaperone
RA 3,142,668 G→T 54.0% L55I (CTC→ATC)  yqhA ← UPF0114 family putative inner membrane protein
RA 3,144,158 C→A 100% intergenic (+253/+19) yghA → / ← exbD putative oxidoreductase/membrane spanning protein in TonB‑ExbB‑ExbD complex
RA 3,152,523 C→A 6.3% A661A (GCG→GCT ygiQ ← Radical SAM superfamily protein
RA 3,154,570 A→C 7.1% intergenic (‑65/+46) ygiQ ← / ← ftsP Radical SAM superfamily protein/septal ring component that protects the divisome from stress; multicopy suppressor of ftsI(Ts)
RA 3,164,049 G→T 36.4% M69I (ATG→ATT qseC → quorum sensing sensory histidine kinase in two‑component regulatory system with QseB
RA 3,164,230 C→A 56.3% R130S (CGT→AGT)  qseC → quorum sensing sensory histidine kinase in two‑component regulatory system with QseB
RA 3,173,669 G→T 100% A189A (GCG→GCT ygiB → DUF1190 family protein
RA 3,176,733 G→T 55.7% intergenic (+51/+439) zupT → / ← ribB zinc transporter/3,4‑dihydroxy‑2‑butanone‑4‑phosphate synthase
RA 3,184,654 A→T 10.2% N222Y (AAT→TAT)  yqiI → fimbrial protein
RA 3,190,985 C→A 13.2% P672P (CCG→CCT glnE ← fused deadenylyltransferase/adenylyltransferase for glutamine synthetase
RA 3,208,581 C→A 39.8% E84D (GAG→GAT mug ← G/U mismatch‑specific DNA glycosylase; xanthine DNA glycosylase
RA 3,211,421 T→A 8.3% K339* (AAG→TAG)  aer ← fused signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component
RA 3,214,709 C→A 7.5% intergenic (‑103/‑116) ygjH ← / → ebgR putative tRNA binding protein; putative tRNA corner chaperone/transcriptional repressor
RA 3,217,289 A→T 54.7% H433L (CAC→CTC)  ebgA → evolved beta‑D‑galactosidase, alpha subunit
RA 3,221,666 G→T 11.2% M169I (ATG→ATT ygjJ → putative periplasmic protein
RA 3,224,927 C→A 100% intergenic (+329/‑97) ygjK → / → fadH alpha‑glucosidase/2,4‑dienoyl‑CoA reductase, NADH and FMN‑linked
RA 3,225,300 C→A 13.7% Q93K (CAG→AAG)  fadH → 2,4‑dienoyl‑CoA reductase, NADH and FMN‑linked
RA 3,226,008 G→T 6.8% A329S (GCC→TCC)  fadH → 2,4‑dienoyl‑CoA reductase, NADH and FMN‑linked
RA 3,229,926 C→A 45.5% L10I (CTC→ATC)  ygjQ → DUF218 superfamily protein
RA 3,230,012 C→A 5.0% R38R (CGC→CGA ygjQ → DUF218 superfamily protein
RA 3,230,492 C→A 6.5% A198A (GCC→GCA ygjQ → DUF218 superfamily protein
RA 3,230,857 C→G 57.0% A63G (GCC→GGC)  ygjR → putative NAD(P)‑dependent dehydrogenase
RA 3,231,349 A→C 47.7% Q227P (CAG→CCG)  ygjR → putative NAD(P)‑dependent dehydrogenase
RA 3,237,654 C→A 5.7% M149I (ATG→ATT uxaC ← uronate isomerase
RA 3,237,920 T→A 10.1% K61* (AAA→TAA)  uxaC ← uronate isomerase
RA 3,245,224 C→A 7.0% P281Q (CCG→CAG)  yqjG → putative S‑transferase
RA 3,245,848 G→T 100% L62L (CTG→CTT yhaH → DUF805 family inner membrane protein
RA 3,246,634 A→T 35.1% intergenic (+8/+43) yhaI → / ← yhaJ DUF805 family inner membrane protein/LysR family putative transcriptional regulator
RA 3,249,389 C→A 10.3% A208S (GCG→TCG)  yhaM ← putative L‑serine dehydratase alpha chain
RA 3,252,258 C→A 100% D251Y (GAT→TAT)  tdcG ← L‑serine dehydratase 3, anaerobic
RA 3,254,793 C→A 17.9% D329Y (GAT→TAT)  tdcE ← pyruvate formate‑lyase 4/2‑ketobutyrate formate‑lyase
RA 3,261,002 A→G 5.6% intergenic (+45/‑211) tdcR → / → yhaB L‑threonine dehydratase operon activator protein/uncharacterized protein
RA 3,263,315 T→C 5.4% intergenic (+354/+260) yhaC → / ← rnpB pentapetide repeats‑related protein/RNase P, M1 RNA component
RA 3,263,466 G→T 43.1% intergenic (+505/+109) yhaC → / ← rnpB pentapetide repeats‑related protein/RNase P, M1 RNA component
RA 3,263,502 C→T 8.6% intergenic (+541/+73) yhaC → / ← rnpB pentapetide repeats‑related protein/RNase P, M1 RNA component
RA 3,266,646 C→A 100% G91C (GGT→TGT)  garL ← alpha‑dehydro‑beta‑deoxy‑D‑glucarate aldolase
RA 3,285,476 C→A 10.5% I259I (ATC→ATA yraK → putative fimbrial‑like adhesin protein
RA 3,296,612 G→T 61.3% A255A (GCG→GCT yhbV → U32 peptidase family protein
RA 3,299,314 C→A 5.6% intergenic (‑138/+16) mtr ← / ← deaD tryptophan transporter of high affinity/ATP‑dependent RNA helicase
RA 3,302,027 G→T 100% S86* (TCG→TAG)  nlpI ← lipoprotein involved in osmotic sensitivity and filamentation
RA 3,312,862 T→A 38.1% R289R (CGT→CGA argG → argininosuccinate synthetase
RA 3,314,870 C→A 100% A35S (GCG→TCG)  yhbX ← putative EptAB family phosphoethanolamine transferase, inner membrane protein
RA 3,324,066 C→A 39.8% E350* (GAA→TAA)  obgE ← GTPase involved in cell partioning and DNA repair
RA 3,329,704 G→T 11.6% V50V (GTC→GTA murA ← UDP‑N‑acetylglucosamine 1‑carboxyvinyltransferase
RA 3,332,963 C→A 38.9% A154A (GCG→GCT mlaF ← ABC transporter maintaining OM lipid asymmetry, ATP‑binding protein
RA 3,334,892 G→T 25.2% D90Y (GAT→TAT)  kdsD → D‑arabinose 5‑phosphate isomerase
RA 3,347,778 G→A 100% intergenic (‑369/‑306) yhcC ← / → gltB putative Fe‑S oxidoreductase, Radical SAM superfamily protein/glutamate synthase, large subunit
RA 3,351,650 G→T 57.1% E1189D (GAG→GAT gltB → glutamate synthase, large subunit
RA 3,354,405 C→T 100% intergenic (+430/‑130) gltD → / → gltF glutamate synthase, 4Fe‑4S protein, small subunit/periplasmic protein
RA 3,357,229 C→A 29.4% S355* (TCG→TAG)  yhcD → putative outer membrane fimbrial subunit usher protein
RA 3,360,045 G→T 20.6% F11L (TTC→TTA insH1 ← IS5 transposase and trans‑activator
RA 3,360,830 A→T 22.0% A182A (GCA→GCT yhcF → putative transcriptional regulator
RA 3,365,607 G→T 100% I109I (ATC→ATA nanT ← sialic acid transporter
RA 3,372,318 G→T 42.9% R347R (CGG→AGG)  yhcM ← putative AFG1‑like family P‑loop ATPase
RA 3,373,985 C→A 100% intergenic (+37/‑117) yhcB → / → degQ DUF1043 family inner membrane‑anchored protein/serine endoprotease, periplasmic
RA 3,374,563 C→A 6.7% I154I (ATC→ATA degQ → serine endoprotease, periplasmic
RA 3,375,260 G→T 100% D387Y (GAT→TAT)  degQ → serine endoprotease, periplasmic
RA 3,380,174 C→A 36.6% S458S (TCG→TCT aaeB ← p‑hydroxybenzoic acid efflux system component
RA 3,384,533 G→T 8.0% V285V (GTC→GTA tldD ← putative peptidase
RA 3,386,672 C→A 39.4% P982P (CCG→CCT yhdP ← DUF3971‑AsmA2 domains protein
RA 3,389,508 C→A 5.9% R37L (CGT→CTT)  yhdP ← DUF3971‑AsmA2 domains protein
RA 3,395,059 C→A 47.0% V545F (GTC→TTC)  csrD ← targeting factor for csrBC sRNA degradation
RA 3,396,082 G→T 100% R204S (CGT→AGT)  csrD ← targeting factor for csrBC sRNA degradation
RA 3,397,316 C→A 7.6% G158G (GGC→GGA acuI → putative acryloyl‑CoA reductase
RA 3,399,100 C→A 43.9% F102L (TTC→TTA accB → acetyl CoA carboxylase, BCCP subunit
RA 3,407,007 G→A 55.8% intergenic (‑183/‑216) acrS ← / → acrE acrAB operon transcriptional repressor/cytoplasmic membrane lipoprotein
RA 3,412,733 G→T 40.8% pseudogene (268/960 nt) yhdW → pseudogene, amino‑acid transporter homology;putative transport; Not classified; putative periplasmic binding transport protein; periplasmic‑binding component of ABC superfamily
RA 3,416,890 T→G 6.7% noncoding (12/120 nt) rrfF ← 5S ribosomal RNA of rrnD operon
RA 3,416,899 A→G 6.1% noncoding (3/120 nt) rrfF ← 5S ribosomal RNA of rrnD operon
RA 3,425,514 C→A 6.3% E104* (GAA→TAA)  smg ← DUF494 family putative periplasmic protein
RA 3,440,151 G→T 100% I31I (ATC→ATA rpsN ← 30S ribosomal subunit protein S14
RA 3,440,444 G→T 100% S118S (TCC→TCA rplE ← 50S ribosomal subunit protein L5
RA 3,440,832 T→C 100% N99D (AAC→GAC)  rplX ← 50S ribosomal subunit protein L24
RA 3,451,616 T→G 33.9% V627V (GTT→GTG gspD → general secretory pathway component, cryptic
RA 3,452,566 C→A 9.5% T290K (ACG→AAG)  gspE → general secretory pathway component, cryptic
RA 3,455,867 C→A 100% I55I (ATC→ATA gspJ → putative general secretory pathway component, cryptic
RA 3,460,771 T→A 13.0% E814D (GAA→GAT chiA ← periplasmic endochitinase
RA 3,473,139 G→T 100% I276I (ATC→ATA kefB ← potassium:proton antiporter
RA 3,479,769 A→T 100% E97D (GAA→GAT crp → cAMP‑activated global transcription factor, mediator of catabolite repression
RA 3,481,214 G→T 10.0% P355P (CCG→CCT yhfK → putative transporter, FUSC superfamily inner membrane protein, tandem domains
RA 3,483,095 C→A 38.7% V149F (GTT→TTT)  argD ← bifunctional acetylornithine aminotransferase/ succinyldiaminopimelate aminotransferase
RA 3,488,966 G→C 100% A533P (GCC→CCC)  nirB → nitrite reductase, large subunit, NAD(P)H‑binding
RA 3,489,397 C→A 100% F676L (TTC→TTA nirB → nitrite reductase, large subunit, NAD(P)H‑binding
RA 3,501,571 C→A 100% G127C (GGC→TGC)  php ← phosphotriesterase homology protein
RA 3,504,143 G→T 59.0% R65S (CGT→AGT)  yhfX ← putative pyridoxal 5'‑phosphate binding protein
RA 3,507,749 G→T 92.3% H224N (CAT→AAT)  rpe ← D‑ribulose‑5‑phosphate 3‑epimerase
RA 3,508,852 G→T 8.6% P141T (CCC→ACC)  dam ← DNA adenine methyltransferase
RA 3,510,311 C→A 37.7% G119C (GGT→TGT)  damX ← cell division protein that binds to the septal ring
RA 3,513,424 A→T 59.5% V213V (GTT→GTA hofQ ← DNA catabolic putative fimbrial transporter
RA 3,519,657 G→T 100% intergenic (‑149/‑171) nudE ← / → yrfF adenosine nucleotide hydrolase; substrates include Ap3A, Ap2A, ADP‑ribose, NADH/inner membrane protein
RA 3,525,950 C→T 33.1% intergenic (‑152/‑227) yhgE ← / → pck DUF4153 family putative inner membrane protein/phosphoenolpyruvate carboxykinase
RA 3,543,775 T→G 9.1% A686A (GCA→GCC malP ← maltodextrin phosphorylase
RA 3,543,959 G→T 100% A625E (GCG→GAG)  malP ← maltodextrin phosphorylase
RA 3,544,521 G→T 24.8% H438N (CAC→AAC)  malP ← maltodextrin phosphorylase
RA 3,545,107 G→T 12.4% A242A (GCC→GCA malP ← maltodextrin phosphorylase
RA 3,561,574 C→A 100% W372L (TGG→TTG)  glgC ← glucose‑1‑phosphate adenylyltransferase
RA 3,566,544 C→A 5.1% E107* (GAA→TAA)  glgB ← 1,4‑alpha‑glucan branching enzyme
RA 3,571,618 C→A 43.7% D157Y (GAT→TAT)  gntR ← d‑gluconate inducible gluconate regulon transcriptional repressor
RA 3,577,507 C→A 43.7% I157I (ATC→ATA insB1 → IS1 transposase B
RA 3,577,849 G→A 11.3% intergenic (+180/‑270) yrhA → / → yrhB pseudogene, interrupted by IS1E/stable heat shock chaperone
RA 3,580,673 G→T 36.6% R124I (AGA→ATA)  yhhA → DUF2756 family protein
RA 3,585,079 C→A 33.6% A203S (GCC→TCC)  ugpB ← glycerol‑3‑phosphate transporter subunit
RA 3,588,904 A→T 37.0% L287Q (CTG→CAG)  livH ← leucine/isoleucine/valine transporter subunit
RA 3,593,024 G→A 5.0% intergenic (‑6/+265) livJ ← / ← rpoH leucine/isoleucine/valine transporter subunit/RNA polymerase, sigma 32 (sigma H) factor
RA 3,595,859 C→A 5.6% M83I (ATG→ATT ftsE ← putative ABC superfamily transporter ATP‑binding subunit
RA 3,609,958 C→A 45.1% I139I (ATC→ATA nikC → nickel transporter subunit
RA 3,612,551 G→T 8.3% intergenic (+202/‑1) nikR → / → rhsB transcriptional repressor, Ni‑binding/Rhs family putative polymorphic toxin, putative neighboring cell growth inhibitor
RA 3,612,708 C→A 48.1% L53I (CTC→ATC)  rhsB → Rhs family putative polymorphic toxin, putative neighboring cell growth inhibitor
RA 3,620,035 C→A 10.6% T43T (ACG→ACT yhhJ ← inner membrane putative ABC transporter permease
RA 3,622,863 G→T 30.2% V12V (GTC→GTA rbbA ← ribosome‑associated ATPase: ATP‑binding protein/ATP‑binding membrane protein
RA 3,629,439 C→A 40.6% intergenic (+186/+129) yhiM → / ← yhiN acid resistance protein, inner membrane/putative oxidoreductase
RA 3,632,600 T→G 40.5% intergenic (+99/+145) pitA → / ← uspB phosphate transporter, low‑affinity; tellurite importer/universal stress (ethanol tolerance) protein B
RA 3,633,738 G→T 7.7% D90Y (GAC→TAC)  uspA → universal stress global response regulator
RA 3,639,551 C→A 35.9% T269T (ACC→ACA rlmJ → 23S rRNA m(6)A2030 methyltransferase, SAM‑dependent
RA 3,642,200 C→A 11.3% R105R (CGA→AGA)  arsR → arsenical resistance operon transcriptional repressor; autorepressor
RA 3,646,763 C→A 7.9% pseudogene (173/483 nt) yhiS → pseudogene
RA 3,652,706 G→T 10.8% V39F (GTC→TTC)  mdtE → anaerobic multidrug efflux transporter, ArcA‑regulated
RA 3,662,660 T→C 100% intergenic (‑112/‑292) yhjA ← / → treF putative cytochrome C peroxidase/cytoplasmic trehalase
RA 3,667,977 C→T 6.0% intergenic (+242/‑169) yhjD → / → yhjE inner membrane putative BrbK family alternate lipid exporter/MFS superfamily sugar transport 1 family protein
RA 3,673,169 C→A 39.5% L131I (CTC→ATC)  kdgK → 2‑dehydro‑3‑deoxygluconokinase
RA 3,679,301 T→G 100% Q1078P (CAG→CCG)  bcsC ← cellulose synthase subunit
RA 3,679,324 C→A 100% M1070I (ATG→ATT bcsC ← cellulose synthase subunit
RA 3,680,910 G→T 100% H542N (CAT→AAT)  bcsC ← cellulose synthase subunit
RA 3,689,369 C→A 9.9% A59A (GCG→GCT yhjR ← DUF2629 family protein
RA 3,698,875 G→T 54.6% F92L (TTC→TTA dppB ← dipeptide/heme transporter
RA 3,701,561 G→A 34.7% intergenic (‑496/+415) dppA ← / ← proK dipeptide transporter/tRNA‑Pro
RA 3,703,272 C→A 35.1% A188A (GCG→GCT eptB ← KDO phosphoethanolamine transferase, Ca(2+)‑inducible
RA 3,708,861 C→A 37.0% E298D (GAG→GAT bisC ← biotin sulfoxide reductase
RA 3,710,595 C→A 6.2% intergenic (+29/‑75) yiaD → / → ghrB multicopy suppressor of bamB; outer membrane lipoprotein/glyoxylate/hydroxypyruvate reductase B
RA 3,717,788 C→A 100% P297P (CCG→CCT glyQ ← glycine tRNA synthetase, alpha subunit
RA 3,718,959 C→A 37.9% L38F (TTG→TTT ysaB ← uncharacterized protein
RA 3,730,615 C→A 32.4% intergenic (‑78/‑242) bax ← / → malS putative glucosaminidase/alpha‑amylase
RA 3,738,431 C→A 100% P90T (CCA→ACA)  yiaN → 2,3‑diketo‑L‑gulonate TRAP transporter large permease protein
RA 3,759,388 C→A 32.9% N1282K (AAC→AAA rhsA → Rhs family protein, putative polymorphic toxin; putative polysaccharide synthesis/export protein; putative neighboring cell growth inhibitor
RA 3,767,000 G→T 51.6% D454Y (GAC→TAC)  mtlA → fused mannitol‑specific PTS enzymes: IIA components/IIB components/IIC components
RA 3,767,143 C→A 5.9% I501I (ATC→ATA mtlA → fused mannitol‑specific PTS enzymes: IIA components/IIB components/IIC components
RA 3,777,313 A→T 5.3% V59E (GTA→GAA)  secB ← protein export chaperone
RA 3,779,324 C→A 42.9% F235L (TTC→TTA gpmM → phosphoglycero mutase III, cofactor‑independent
RA 3,779,927 T→A 6.1% G436G (GGT→GGA gpmM → phosphoglycero mutase III, cofactor‑independent
RA 3,785,915 G→T 100% intergenic (‑4/+271) kbl ← / ← yibB glycine C‑acetyltransferase/YibB family protein, function unknown
RA 3,791,588 T→A 36.5% intergenic (+21/+11) waaL → / ← waaU O‑antigen ligase/lipopolysaccharide core biosynthesis
RA 3,793,653 G→T 44.3% R225S (CGT→AGT)  waaY ← lipopolysaccharide core biosynthesis protein
RA 3,793,839 G→T 8.5% R163S (CGT→AGT)  waaY ← lipopolysaccharide core biosynthesis protein
RA 3,799,108 C→A 40.8% R68L (CGG→CTG)  waaP ← kinase that phosphorylates core heptose of lipopolysaccharide
RA 3,801,096 C→A 6.5% A121A (GCG→GCT waaQ ← lipopolysaccharide core biosynthesis protein
RA 3,810,195 C→A 100% R54S (CGT→AGT)  yicC → UPF0701 family protein
RA 3,813,429 T→A 5.7% S368C (AGC→TGC)  ligB ← DNA ligase, NAD(+)‑dependent
RA 3,814,302 T→A 38.3% S77C (AGC→TGC)  ligB ← DNA ligase, NAD(+)‑dependent
RA 3,816,601 A→T 100% H281L (CAC→CTC)  spoT → bifunctional (p)ppGpp synthetase II/ guanosine‑3',5'‑bis pyrophosphate 3'‑pyrophosphohydrolase
RA 3,817,272 C→A 5.0% Q505K (CAG→AAG)  spoT → bifunctional (p)ppGpp synthetase II/ guanosine‑3',5'‑bis pyrophosphate 3'‑pyrophosphohydrolase
RA 3,818,010 C→A 100% H46N (CAT→AAT)  trmH → tRNA mG18‑2'‑O‑methyltransferase, SAM‑dependent
RA 3,819,936 C→A 44.3% T456K (ACG→AAG)  recG → ATP‑dependent DNA helicase
RA 3,822,340 A→C 7.6% Q12H (CAA→CAC xanP → xanthine permease
RA 3,825,702 C→A 100% K732N (AAG→AAT yicI ← putative alpha‑glucosidase
RA 3,828,206 T→A 5.2% S362C (AGT→TGT)  yicJ ← putative transporter
RA 3,830,197 C→A 100% intergenic (+281/‑116) yicT → / → setC pseudogene/putative arabinose efflux transporter
RA 3,830,311 G→T 100% intergenic (+395/‑2) yicT → / → setC pseudogene/putative arabinose efflux transporter
RA 3,835,154 G→A 44.2% intergenic (‑55/+156) nepI ← / ← yicN putative transporter/DUF1198 family protein
RA 3,840,727 C→A 5.5% A420S (GCC→TCC)  uhpC ← membrane protein regulates uhpT expression
RA 3,844,347 C→A 11.2% V36F (GTT→TTT)  ilvN ← acetolactate synthase 1 small subunit
RA 3,846,307 C→A 8.0% A14A (GCG→GCT ivbL ← ilvB operon leader peptide
RA 3,847,167 C→A 5.0% intergenic (+165/‑115) tisB → / → emrD toxic membrane persister formation peptide, LexA‑regulated/multidrug efflux system protein
RA 3,851,275 G→T 9.7% H164N (CAT→AAT)  yidJ ← sulfatase/phosphatase superfamily protein
RA 3,858,274 A→C 35.6% F454V (TTT→GTT)  yidE ← putative transporter
RA 3,860,159 C→A 100% P33P (CCG→CCT ibpB ← heat shock chaperone
RA 3,860,327 C→A 58.4% intergenic (‑70/+42) ibpB ← / ← ibpA heat shock chaperone/heat shock chaperone
RA 3,860,653 C→A 63.0% E44* (GAA→TAA)  ibpA ← heat shock chaperone
RA 3,865,120 C→A 57.2% intergenic (‑30/+90) dgoT ← / ← dgoD D‑galactonate transporter/galactonate dehydratase
RA 3,867,062 C→A 35.3% R258L (CGC→CTC)  dgoK ← 2‑oxo‑3‑deoxygalactonate kinase
RA 3,877,248 C→A 5.6% intergenic (‑159/‑448) dnaA ← / → rpmH chromosomal replication initiator protein DnaA, DNA‑binding transcriptional dual regulator/50S ribosomal subunit protein L34
RA 3,879,501 T→A 45.2% F356I (TTC→ATC)  yidC → membrane protein insertase
RA 3,889,578 C→A 43.9% R131L (CGC→CTC)  purP ← adenine permease, high affinity; adenine:H+ symporter
RA 3,890,865 T→A 8.7% intergenic (+66/‑1) yieH → / → cbrB phosphoenolpyruvate and 6‑phosphogluconate phosphatase/PRK09823 family inner membrane protein, creBC regulon
RA 3,894,632 C→A 29.4% V317F (GTC→TTC)  bglH ← carbohydrate‑specific outer membrane porin, cryptic
RA 3,900,078 G→A 5.9% intergenic (‑151/+135) bglG ← / ← phoU transcriptional antiterminator of the bgl operon/negative regulator of PhoR/PhoB two‑component regulator
RA 3,901,867 T→G 5.3% intergenic (‑141/+42) pstB ← / ← pstA phosphate transporter subunit/phosphate transporter subunit
RA 3,903,417 G→T 6.7% I114I (ATC→ATA pstC ← phosphate transporter subunit
RA 3,910,894 C→A 100% M244I (ATG→ATT atpG ← F1 sector of membrane‑bound ATP synthase, gamma subunit
RA 3,916,052 C→A 39.1% intergenic (‑252/+365) atpI ← / ← rsmG ATP synthase, membrane‑bound accessory factor/16S rRNA m(7)G527 methyltransferase, SAM‑dependent; glucose‑inhibited cell‑division protein
RA 3,916,830 C→A 100% D71Y (GAT→TAT)  rsmG ← 16S rRNA m(7)G527 methyltransferase, SAM‑dependent; glucose‑inhibited cell‑division protein
RA 3,921,331 C→A 6.6% R273S (CGC→AGC)  asnA → asparagine synthetase A
RA 3,923,028 C→A 50.6% D476Y (GAC→TAC)  ravA ← hexameric AAA+ MoxR family ATPase, putative molecular chaperone
RA 3,926,536 G→T 8.7% E621* (GAA→TAA)  kup → potassium transporter
RA 3,926,831 G→T 94.1% D41Y (GAT→TAT)  rbsD → putative cytoplasmic sugar‑binding protein
RA 3,927,972 G→T 56.6% E279* (GAA→TAA)  rbsA → fused D‑ribose transporter subunits of ABC superfamily: ATP‑binding components
RA 3,930,795 G→T 6.6% A48S (GCT→TCT)  rbsK → ribokinase
RA 3,933,680 G→T 7.2% S98* (TCG→TAG)  hsrA ← putative multidrug or homocysteine efflux system
RA 3,933,862 G→T 41.5% I37I (ATC→ATA hsrA ← putative multidrug or homocysteine efflux system
RA 3,933,926 G→T 6.4% A16E (GCG→GAG)  hsrA ← putative multidrug or homocysteine efflux system
RA 3,935,100 G→T 58.2% intergenic (‑413/‑68) yieP ← / → rrsC putative transcriptional regulator/16S ribosomal RNA of rrnC operon
RA 3,945,503 A→T 45.6% pseudogene (602/663 nt) ilvG → pseudogene, acetolactate synthase 2 large subunit, valine‑insensitive; acetolactate synthase II, large subunit, cryptic, interrupted
RA 3,950,395 C→A 33.9% E262D (GAG→GAT ilvY ← transcriptional activator of ilvC; autorepressor
RA 3,952,658 C→T 38.2% D443D (GAC→GAT ilvC → ketol‑acid reductoisomerase, NAD(P)‑binding
RA 3,952,842 A→C 10.6% intergenic (+37/+50) ilvC → / ← ppiC ketol‑acid reductoisomerase, NAD(P)‑binding/peptidyl‑prolyl cis‑trans isomerase C (rotamase C)
RA 3,956,165 C→A 45.1% E475D (GAG→GAT gpp ← guanosine pentaphosphatase/exopolyphosphatase
RA 3,960,036 G→A 100% R87H (CGC→CAC)  rho → transcription termination factor
RA 3,966,854 C→A 100% R325S (CGT→AGT)  rffG → dTDP‑glucose 4,6‑dehydratase
RA 3,967,474 G→T 57.6% A169A (GCG→GCT rffH → glucose‑1‑phosphate thymidylyltransferase
RA 3,969,710 G→T 100% G25C (GGT→TGT)  wzxE → O‑antigen translocase
RA 3,970,026 C→A 38.0% A130D (GCC→GAC)  wzxE → O‑antigen translocase
RA 3,977,650 A→T 45.1% intergenic (+97/+62) aslB → / ← aslA putative AslA‑specific sulfatase‑maturating enzyme/putative Ser‑type periplasmic non‑aryl sulfatase
RA 3,978,810 G→T 15.6% I186I (ATC→ATA aslA ← putative Ser‑type periplasmic non‑aryl sulfatase
RA 3,988,075 T→A 100% V65E (GTG→GAG)  yifL → putative lipoprotein
RA 3,990,572 C→A 45.4% I10I (ATC→ATA yigB → 5‑amino‑6‑(5‑phospho‑D‑ribitylamino)uracil phosphatase; pyrimidine phosphatase; riboflavin synthesis
RA 3,992,341 G→T 7.6% V333V (GTG→GTT uvrD → DNA‑dependent ATPase I and helicase II
RA 3,994,076 A→T 100% L114* (TTA→TAA)  yigE ← DUF2233 family protein
RA 3,994,247 A→T 100% V57E (GTG→GAG)  yigE ← DUF2233 family protein
RA 4,000,333 G→T 6.9% A370A (GCG→GCT recQ → ATP‑dependent DNA helicase
RA 4,009,705 G→A 100% intergenic (‑176/‑86) ysgA ← / → udp putative carboxymethylenebutenolidase/uridine phosphorylase
RA 4,019,131 G→T 9.4% D262Y (GAT→TAT)  ubiD → 3‑octaprenyl‑4‑hydroxybenzoate decarboxylase
RA 4,024,827 G→T 60.7% D103Y (GAT→TAT)  pepQ → proline dipeptidase
RA 4,035,421 G→T 54.8% intergenic (‑62/‑8) mobA ← / → yihD molybdopterin‑guanine dinucleotide synthase/DUF1040 protein YihD
RA 4,046,172 A→T 46.5% K256N (AAA→AAT hemN → coproporphyrinogen III oxidase, SAM and NAD(P)H dependent, oxygen‑independent
RA 4,052,201 C→A 37.3% F145L (TTC→TTA typA → GTP‑binding protein
RA 4,055,246 T→A 8.4% L241Q (CTG→CAG)  yihM → putative sugar phosphate isomerase
RA 4,056,018 T→A 100% F138I (TTC→ATC)  yihN → MFS transporter family protein
RA 4,062,424 G→T 100% I71I (ATC→ATA yihQ ← alpha‑glucosidase
RA 4,066,133 T→G 100% S267R (AGC→CGC)  yihU ← gamma‑hydroxybutyrate dehydrogenase, NADH‑dependent
RA 4,068,208 C→A 100% G60G (GGC→GGA yihW → DeoR family putative transcriptional regulator
RA 4,069,390 G→T 10.9% D160Y (GAT→TAT)  yihX → alpha‑D‑Glucose‑1‑P phosphatase, anomer‑specific
RA 4,077,665 G→T 45.5% V506V (GTC→GTA fdoG ← formate dehydrogenase‑O, large subunit
RA 4,087,476 A→T 36.4% intergenic (‑126/‑188) rhaD ← / → rhaS pseudogene, truncated, rhamnulose‑phosphate aldolase/transcriptional activator of rhaBAD and rhaT
RA 4,087,754 C→A 44.4% H31N (CAT→AAT)  rhaS → transcriptional activator of rhaBAD and rhaT
RA 4,094,362 C→A 100% W181L (TGG→TTG)  cpxA ← sensory histidine kinase in two‑component regulatory system with CpxR
RA 4,095,124 C→T 46.1% G159S (GGT→AGT)  cpxR ← response regulator in two‑component regulatory system with CpxA
RA 4,096,555 G→T 7.2% S53S (TCG→TCT fieF → ferrous iron and zinc transporter
RA 4,097,282 C→A 38.0% R296R (CGG→AGG)  fieF → ferrous iron and zinc transporter
RA 4,097,822 G→T 100% E115* (GAA→TAA)  pfkA → 6‑phosphofructokinase I
RA 4,105,186 C→A 33.6% D108Y (GAT→TAT)  glpX ← fructose 1,6‑bisphosphatase II
RA 4,105,662 A→T 37.8% W497R (TGG→AGG)  glpK ← glycerol kinase
RA 4,122,248 A→T 56.0% intergenic (+53/‑296) metL → / → metF Bifunctional aspartokinase/homoserine dehydrogenase 2/5,10‑methylenetetrahydrofolate reductase
RA 4,127,022 T→G 100% E188D (GAA→GAC yijF ← DUF1287 family protein
RA 4,134,111 G→T 41.4% L63L (CTG→CTT pflD → putative glycine radical domain‑containing pyruvate formate‑lyase
RA 4,143,375 A→G 8.2% intergenic (‑349/+249) ppc ← / ← argE phosphoenolpyruvate carboxylase/acetylornithine deacetylase
RA 4,143,605 G→T 35.9% intergenic (‑579/+19) ppc ← / ← argE phosphoenolpyruvate carboxylase/acetylornithine deacetylase
RA 4,144,787 C→A 39.4% intergenic (‑12/‑142) argE ← / → argC acetylornithine deacetylase/N‑acetyl‑gamma‑glutamylphosphate reductase, NAD(P)‑binding
RA 4,145,195 G→T 37.9% A89A (GCG→GCT argC → N‑acetyl‑gamma‑glutamylphosphate reductase, NAD(P)‑binding
RA 4,150,043 G→T 38.4% H226N (CAC→AAC)  sthA ← pyridine nucleotide transhydrogenase, soluble
RA 4,150,197 G→T 8.6% H174Q (CAC→CAA sthA ← pyridine nucleotide transhydrogenase, soluble
RA 4,154,083 G→T 10.2% D173Y (GAT→TAT)  btuB → vitamin B12/cobalamin outer membrane transporter
RA 4,163,570 T→A 44.3% I187I (ATT→ATA birA → bifunctional biotin‑[acetylCoA carboxylase] holoenzyme synthetase/ DNA‑binding transcriptional repressor, bio‑5'‑AMP‑binding
RA 4,168,773 A→T 36.8% A133A (GCA→GCT rplK → 50S ribosomal subunit protein L11
RA 4,173,145 A→T 60.9% Q658L (CAG→CTG)  rpoB → RNA polymerase, beta subunit
RA 4,173,546 G→T 8.1% G792C (GGT→TGT)  rpoB → RNA polymerase, beta subunit
RA 4,176,823 G→T 100% D516Y (GAC→TAC)  rpoC → RNA polymerase, beta prime subunit
RA 4,178,758 G→T 32.4% G1161C (GGT→TGT)  rpoC → RNA polymerase, beta prime subunit
RA 4,198,010 T→A 25.7% intergenic (‑550/‑65) purH ← / → rrsE fused IMP cyclohydrolase/phosphoribosylaminoimidazolecarboxamide formyltransferase/16S ribosomal RNA of rrnE operon
RA 4,207,552 G→T 53.0% M172I (ATG→ATT aceA → isocitrate lyase
RA 4,207,558 G→T 37.6% A174A (GCG→GCT aceA → isocitrate lyase
RA 4,208,354 G→T 9.6% intergenic (+13/‑170) aceA → / → aceK isocitrate lyase/isocitrate dehydrogenase kinase/phosphatase
RA 4,211,576 G→T 100% S280R (AGC→AGA arpA ← ankyrin repeat protein
RA 4,211,803 G→A 100% P205S (CCT→TCT)  arpA ← ankyrin repeat protein
RA 4,214,563 A→T 52.8% T270S (ACC→TCC)  metH → homocysteine‑N5‑methyltetrahydrofolate transmethylase, B12‑dependent
RA 4,218,928 G→A 40.9% E424K (GAA→AAA)  yjbB → putative Na+/Pi‑cotransporter
RA 4,220,948 G→T 42.3% D223Y (GAT→TAT)  rluF → 23S rRNA pseudouridine(2604) synthase
RA 4,222,642 G→T 7.8% L174I (CTC→ATC)  lysC ← lysine‑sensitive aspartokinase 3
RA 4,230,913 A→T 100% W424R (TGG→AGG)  xylE ← D‑xylose transporter
RA 4,235,869 G→T 50.1% A160E (GCG→GAG)  malE ← maltose transporter subunit
RA 4,241,633 C→T 36.3% pseudogene (745/1323 nt) yjbI → pseudogene, SopA‑related, pentapeptide repeats‑containing
RA 4,242,509 C→T 54.7% L26F (CTC→TTC)  ubiC → chorismate‑‑pyruvate lyase
RA 4,247,553 A→T 6.0% N171Y (AAT→TAT)  lexA → transcriptional repressor of SOS regulon
RA 4,257,593 C→T 7.0% N184N (AAC→AAT tyrB → tyrosine aminotransferase, tyrosine‑repressible, PLP‑dependent
RA 4,265,064 C→A 94.7% intergenic (‑95/‑335) yjcB ← / → yjcC putative inner membrane protein/putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 4,271,906 C→T 38.0% E366E (GAG→GAA yjcF ← pentapeptide repeats protein
RA 4,273,297 A→T 36.7% W512R (TGG→AGG)  actP ← acetate transporter
RA 4,274,926 A→C 100% I72M (ATT→ATG yjcH ← DUF485 family inner membrane protein
RA 4,275,142 C→A 100% intergenic (‑1/+199) yjcH ← / ← acs DUF485 family inner membrane protein/acetyl‑CoA synthetase
RA 4,278,325 T→A 38.8% C212S (TGC→AGC)  nrfA → nitrite reductase, formate‑dependent, cytochrome
RA 4,284,205 T→C 7.8% intergenic (+138/‑204) nrfG → / → gltP heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfG/glutamate/aspartate:proton symporter
RA 4,285,213 G→T 41.6% D269Y (GAT→TAT)  gltP → glutamate/aspartate:proton symporter
RA 4,286,311 C→A 38.5% S211I (AGC→ATC)  yjcO ← Sel1 family TPR‑like repeat protein
RA 4,290,080 G→T 100% I256I (ATC→ATA mdtP ← outer membrane factor of efflux pump
RA 4,297,485 G→C 57.4% G44G (GGC→GGG alsK ← D‑allose kinase
RA 4,297,846 C→A 100% M150I (ATG→ATT alsE ← allulose‑6‑phosphate 3‑epimerase
RA 4,300,333 T→A 37.8% E155D (GAA→GAT alsA ← fused D‑allose transporter subunits of ABC superfamily: ATP‑binding components
RA 4,303,614 T→A 100% *150R (TGA→AGA)  rpiB → ribose 5‑phosphate isomerase B/allose 6‑phosphate isomerase
RA 4,304,151 T→G 5.6% intergenic (+137/+10) yjdP → / ← phnP putative periplasmic protein/5‑phospho‑alpha‑D‑ribosyl 1,2‑cyclic phosphate phosphodiesterase
RA 4,308,395 G→T 32.6% H63N (CAC→AAC)  phnK ← carbon‑phosphorus lyase complex subunit, putative ATP transporter ATP‑binding protein
RA 4,315,765 A→G 5.9% intergenic (‑207/+451) yjdN ← / ← yjdM metalloprotein superfamily protein/zinc‑ribbon family protein
RA 4,316,794 G→A 5.7% intergenic (‑243/‑158) yjdM ← / → crfC zinc‑ribbon family protein/clamp‑binding sister replication fork colocalization protein, dynamin‑related
RA 4,317,974 G→T 37.8% A341A (GCG→GCT crfC → clamp‑binding sister replication fork colocalization protein, dynamin‑related
RA 4,330,426 Δ1 bp 100% intergenic (‑88/+111) adiA ← / ← melR arginine decarboxylase/melibiose operon transcriptional regulator; autoregulator
RA 4,331,530 T→A 8.2% intergenic (‑85/‑198) melR ← / → melA melibiose operon transcriptional regulator; autoregulator/alpha‑galactosidase, NAD(P)‑binding
RA 4,335,003 A→T 11.8% Y125N (TAC→AAC)  yjdF ← DUF2238 family inner membrane protein
RA 4,335,195 G→T 31.9% L61I (CTC→ATC)  yjdF ← DUF2238 family inner membrane protein
RA 4,335,352 T→A 5.1% L8F (TTA→TTT yjdF ← DUF2238 family inner membrane protein
RA 4,336,681 A→T 40.3% Y155N (TAC→AAC)  fumB ← anaerobic class I fumarate hydratase (fumarase B)
RA 4,337,717 G→T 43.1% A282E (GCG→GAG)  dcuB ← C4‑dicarboxylate transporter, anaerobic; DcuS co‑sensor
RA 4,341,023 A→T 94.1% Y153N (TAC→AAC)  dcuS ← sensory histidine kinase in two‑component regulatory system with DcuR, regulator of anaerobic fumarate respiration
RA 4,345,995 C→A 44.0% V78V (GTG→GTT dtpC ← dipeptide and tripeptide permease
RA 4,346,015 G→T 41.9% L72I (CTC→ATC)  dtpC ← dipeptide and tripeptide permease
RA 4,348,443 C→A 13.1% intergenic (‑9/+71) cadA ← / ← cadB lysine decarboxylase, acid‑inducible/putative lysine/cadaverine transporter
RA 4,354,610 A→T 44.5% W84R (TGG→AGG)  dsbD ← fused thiol:disulfide interchange protein: activator of DsbC/conserved protein
RA 4,356,312 G→T 8.5% I93I (ATC→ATA dcuA ← C4‑dicarboxylate antiporter
RA 4,357,095 A→C 49.5% V350V (GTT→GTG aspA ← aspartate ammonia‑lyase
RA 4,358,920 G→T 58.9% R147L (CGC→CTC)  fxsA → suppressor of F exclusion of phage T7
RA 4,372,891 A→T 42.9% A144A (GCA→GCT epmA → Elongation Factor P Lys34 lysyltransferase
RA 4,376,178 C→A 59.7% E1004* (GAA→TAA)  mscM ← mechanosensitive channel protein, miniconductance
RA 4,378,778 G→T 59.0% S137* (TCG→TAG)  mscM ← mechanosensitive channel protein, miniconductance
RA 4,382,399 A→C 8.0% intergenic (+35/‑1) glyX → / → glyY tRNA‑Gly/tRNA‑Gly
RA 4,388,902 G→T 100% A558A (GCG→GCT mutL → methyl‑directed mismatch repair protein
RA 4,394,391 G→T 6.3% T63T (ACG→ACT yjeT → DUF2065 family protein
RA 4,394,875 G→T 57.7% A124A (GCG→GCT purA → adenylosuccinate synthetase
RA 4,396,598 A→T 100% E43V (GAA→GTA)  rnr → exoribonuclease R, RNase R
RA 4,402,850 G→T 53.8% L2L (CTG→CTT yjfC → ATP‑Grasp family ATPase
RA 4,405,735 G→T 40.3% intergenic (+18/+99) aidB → / ← yjfN DNA alkylation damage repair protein; flavin‑containing DNA binding protein, weak isovaleryl CoA dehydrogenase/DUF1471 family periplasmic protein
RA 4,417,551 A→C 100% pseudogene (41/402 nt) ytfA → pseudogene, related to transcriptional regulators
RA 4,421,791 G→T 7.1% R4S (CGC→AGC)  ytfE ← iron‑sulfur cluster repair protein RIC
RA 4,428,092 G→T 61.9% G190V (GGA→GTA)  ytfI → uncharacterized protein
RA 4,440,321 C→A 34.8% I181I (ATC→ATA ytfQ → galactofuranose binding proteint: periplasmic‑binding component of ABC superfamily
RA 4,458,254 T→A 100% V271V (GTT→GTA mgtA → magnesium transporter
RA 4,458,609 G→T 100% D390Y (GAT→TAT)  mgtA → magnesium transporter
RA 4,463,091 G→T 5.3% intergenic (‑65/+66) yjgH ← / ← bdcA UPF0131 family protein/c‑di‑GMP‑binding biofilm dispersal mediator protein
RA 4,465,624 C→T 35.3% S124F (TCC→TTC)  yjgL → uncharacterized protein
RA 4,468,165 A→G 100% intergenic (‑37/‑125) argI ← / → rraB ornithine carbamoyltransferase 1/protein inhibitor of RNase E
RA 4,469,550 G→A 100% A2T (GCT→ACT)  yjgN → DUF898 family inner membrane protein
RA 4,470,017 G→A 100% M157I (ATG→ATA yjgN → DUF898 family inner membrane protein
RA 4,470,873 G→T 58.5% R928S (CGT→AGT)  valS ← valyl‑tRNA synthetase
RA 4,474,993 G→T 44.5% S259* (TCG→TAG)  pepA ← multifunctional aminopeptidase A: a cyteinylglycinase, transcription regulator and site‑specific recombination factor
RA 4,480,249 G→T 8.8% S236R (AGC→AGA idnR ← transcriptional repressor, 5‑gluconate‑binding
RA 4,481,249 A→T 33.4% V365E (GTG→GAG)  idnT ← L‑idonate and D‑gluconate transporter
RA 4,487,680 G→T 7.9% pseudogene (1189/1266 nt) intB → pseudogene, integrase homology;IS, phage, Tn; Phage‑related functions and prophages; KpLE2 phage‑like element; P4‑like integrase
RA 4,494,721 G→A 51.6% A283T (GCC→ACC)  yjhB → putative transporter
RA 4,495,349 G→T 48.0% K82N (AAG→AAT yjhC → putative oxidoreductase
RA 4,495,560 A→T 35.4% N153Y (AAC→TAC)  yjhC → putative oxidoreductase
RA 4,512,693 T→A 100% K407* (AAG→TAG)  yjhG ← putative dehydratase
RA 4,516,177 C→A 23.3% D177Y (GAT→TAT)  sgcR ← putative DNA‑binding transcriptional regulator
RA 4,523,001 T→A 57.2% intergenic (‑1/+55) yjhP ← / ← yjhQ putative methyltransferase/putative acetyltransferase
RA 4,524,073 G→T 8.8% intergenic (‑203/+174) yjhX ← / ← yjhZ UPF0386 family protein/pseudogene, rimK paralog, C‑terminal fragment
RA 4,525,234 G→A 100% pseudogene (415/1029 nt) yjhR → pseudogene, helicase family; putative frameshift suppressor
RA 4,531,143 A→T 100% I124F (ATT→TTT)  fimB → tyrosine recombinase/inversion of on/off regulator of fimA
RA 4,531,461 G→A 24.5% intergenic (+85/‑393) fimB → / → fimE tyrosine recombinase/inversion of on/off regulator of fimA/tyrosine recombinase/inversion of on/off regulator of fimA
RA 4,534,644 C→T 8.6% S175F (TCT→TTT)  fimC → periplasmic chaperone
RA 4,535,507 C→A 38.9% R199R (CGG→AGG)  fimD → fimbrial usher outer membrane porin protein; FimCD chaperone‑usher
RA 4,541,445 G→A 11.1% intergenic (‑332/‑8) gntP ← / → uxuA fructuronate transporter/mannonate hydrolase
RA 4,541,449 A→T 54.7% intergenic (‑336/‑4) gntP ← / → uxuA fructuronate transporter/mannonate hydrolase
RA 4,545,657 C→A 8.5% G161* (GGA→TGA)  yjiC ← uncharacterized protein
RA 4,552,902 A→T 33.2% N173K (AAT→AAA yjiK ← SdiA‑regulated family putative membrane‑anchored protein; putative phytase‑like esterase
RA 4,555,156 G→T 100% A171E (GCG→GAG)  yjiM ← putative 2‑hydroxyglutaryl‑CoA dehydratase
RA 4,555,620 T→G 7.9% E16D (GAA→GAC yjiM ← putative 2‑hydroxyglutaryl‑CoA dehydratase
RA 4,562,043 C→A 100% intergenic (+311/‑188) yjiS → / → yjiT DUF1127 family protein/pseudogene
RA 4,565,742 C→A 42.0% pseudogene (2007/2937 nt) yjiV → pseudogene; conserved hypothetical protein
RA 4,571,233 G→A 49.3% S16F (TCT→TTT)  hsdS ← specificity determinant for hsdM and hsdR
RA 4,572,581 G→T 37.3% T95T (ACC→ACA hsdM ← DNA methyltransferase M
RA 4,572,800 A→T 42.1% V22V (GTT→GTA hsdM ← DNA methyltransferase M
RA 4,583,316 C→A 6.5% P408P (CCG→CCT yjjL ← L‑galactonate transporter
RA 4,584,381 G→T 100% I53I (ATC→ATA yjjL ← L‑galactonate transporter
RA 4,584,756 A→T 56.2% *305K (TAA→AAA)  yjjM ← yjjMN operon transcriptional activator
RA 4,585,338 A→T 100% S111T (TCT→ACT)  yjjM ← yjjMN operon transcriptional activator
RA 4,590,074 A→C 31.8% V240G (GTA→GGA)  dnaC ← DNA biosynthesis protein
RA 4,591,139 C→A 54.2% D66Y (GAT→TAT)  dnaT ← DNA biosynthesis protein (primosomal protein I)
RA 4,593,035 G→T 6.3% intergenic (‑360/‑259) yjjP ← / → yjjQ pseudogene, premature stop codon, putative structural protein/putative transcriptional regulator
RA 4,593,513 T→G 48.8% Y74D (TAT→GAT)  yjjQ → putative transcriptional regulator
RA 4,596,243 T→A 57.2% intergenic (‑25/+243) leuQ ← / ← rsmC tRNA‑Leu/16S rRNA m(2)G1207 methyltransferase, SAM‑dependent
RA 4,602,307 T→A 44.8% L27Q (CTG→CAG)  yjjU → putative patatin‑like family phospholipase
RA 4,603,666 G→T 5.7% A123A (GCG→GCT yjjV → putative DNase
RA 4,604,195 A→G 5.2% intergenic (+118/+302) yjjV → / ← yjjW putative DNase/putative pyruvate formate lyase activating enzyme
RA 4,604,240 T→A 5.2% intergenic (+163/+257) yjjV → / ← yjjW putative DNase/putative pyruvate formate lyase activating enzyme
RA 4,612,781 C→A 7.5% A399E (GCG→GAG)  yjjJ → putative protein kinase
RA 4,617,009 G→T 9.2% A427A (GCG→GCT radA → DNA repair protein
RA 4,618,602 T→C 12.2% intergenic (+238/+70) nadR → / ← yjjK trifunctional protein: nicotinamide mononucleotide adenylyltransferase, ribosylnicotinamide kinase, transcriptional repressor/putative transporter subunit of ABC superfamily: ATP‑binding component
RA 4,625,288 T→C 100% intergenic (‑161/‑50) rob ← / → creA right oriC‑binding transcriptional activator, AraC family/putative periplasmic protein
RA 4,628,799 G→T 5.1% D269Y (GAT→TAT)  creD → inner membrane protein
RA 4,629,649 A→T 46.6% Y159N (TAC→AAC)  arcA ← response regulator in two‑component regulatory system with ArcB or CpxA

Unassigned missing coverage evidence
   seq id start end size ←reads reads→ gene description
* * ÷ CP009273 373853 375146 1294 165 [162] [161] 168 frmA–[frmR] frmA,[frmR]
* * ÷ CP009273 4100601 4101530 930 163 [162] [160] 163 [cdh]–tpiA [cdh],tpiA

Unassigned new junction evidence
  seq id position reads (cov) reads (cov) score skew freq annotation gene product
* ? CP009273 360104 =200 (0.840)201 (0.840) 115/278 NT 50.1% intergenic (‑38/+557) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 360286 NA (NA)intergenic (‑220/+375) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
* ? CP009273 = 360278NA (NA)6140 (27.240)
+TTAATTAA
195/262 NT 96.0% intergenic (‑212/+383) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 361823 271 (1.130)coding (831/834 nt) mhpR mhp operon transcriptional activator
* ? CP009273 360652 =234 (0.980)5897 (36.970)
+46 bp
185/186 NT 97.5% intergenic (‑586/+9) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 1317577 211 (0.880)coding (101/882 nt) yciV PHP domain protein
* ? CP009273 376716 =NA (NA)227 (0.950) 125/278 NT 99.6% intergenic (‑1/‑91) yaiX/insC1 pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase/IS2 repressor TnpA
?CP009273 566411 = 1 (0.000)coding (63/552 nt) ybcL inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family
* ? CP009273 = 378046NA (NA)249 (1.040) 124/278 NT 100% intergenic (+11/+1) insD1/yaiX IS2 transposase TnpB/pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase
?CP009273 = 566415 0 (0.000)coding (67/552 nt) ybcL inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family
* ? CP009273 1203246 =9 (0.040)69 (0.330) 50/246 NT 85.2% coding (290/630 nt) stfP e14 prophage; uncharacterized protein
?CP009273 1205075 = 16 (0.080)pseudogene (1/501 nt) stfE pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
* ? CP009273 = 120326110 (0.040)83 (0.390) 53/246 NT 87.0% coding (305/630 nt) stfP e14 prophage; uncharacterized protein
?CP009273 = 1205058 16 (0.080)pseudogene (18/501 nt) stfE pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
* ? CP009273 = 1282540137 (0.570)8 (0.040) 6/238 NT 5.4% noncoding (153/171 nt) rttR rtT sRNA, processed from tyrT transcript
?CP009273 1283013 = 162 (0.790)noncoding (66/85 nt) tyrT tRNA‑Tyr
* ? CP009273 1635219 =0 (0.000)222 (0.940) 139/274 NT 100% intergenic (‑377/+377) essQ/cspB Qin prophage; putative S lysis protein/Qin prophage; cold shock protein
?CP009273 = 2063752 NA (NA)noncoding (1/1331 nt) IS2 repeat region
* ? CP009273 = 16352230 (0.000)202 (0.840) 124/278 NT 100% intergenic (‑381/+373) essQ/cspB Qin prophage; putative S lysis protein/Qin prophage; cold shock protein
?CP009273 = 1645805 NA (NA)intergenic (+11/‑3) insD1/intQ IS2 transposase TnpB;IS, phage, Tn; Transposon‑related functions; extrachromosomal; transposon related/pseudogene, Qin prophage; phage integrase family;Phage or Prophage Related
* ? CP009273 = 3180783NA (NA)131 (0.560) 91/274 NT 54.3% pseudogene (4/2445 nt) yqiG pseudogene; fimbrial export usher family;putative membrane; Not classified; putative membrane protein
?CP009273 = 3833569 112 (0.470)intergenic (‑216/‑6) nlpA/yicS cytoplasmic membrane lipoprotein‑28/putative periplasmic protein
* ? CP009273 3833562 =113 (0.470)129 (0.540) 79/276 NT 53.5% intergenic (‑209/‑13) nlpA/yicS cytoplasmic membrane lipoprotein‑28/putative periplasmic protein
?CP009273 4487999 = NA (NA)intergenic (+242/‑90) intB/insC1 pseudogene, integrase homology;IS, phage, Tn; Phage‑related functions and prophages; KpLE2 phage‑like element; P4‑like integrase/IS2 repressor TnpA