Predicted mutations
position mutation output GATK_CNVnator annotation gene description
2,054 A→G 100%99.6% H573R (CAC→CGC)  thrA → aspartokinase I
34,120 (T)9→8 100%98.1% coding (146/180 nt) yaaV ← hypothetical protein
39,749 T→C 100%99.2% D213G (GAC→GGC)  caiA ← putative carnitine operon oxidoreductase
41,228 A→C 100%98.7% I235S (ATC→AGC)  caiT ← putative carnitine transporter
51,728 C→T 54.2% V235I (GTC→ATC)  ksgA ← S‑adenosylmethionine‑6‑N',N'‑adenosyl (rRNA) dimethyltransferase
66,528 T→C 100% Q8R (CAG→CGG)  araD ← L‑ribulose‑5‑phosphate 4‑epimerase
66,533 3540 bp→27 bp 100% [araD]araB [araD], araA, araB
70,289 G→T 100%100% intergenic (‑241/‑98) araB ← / → araC L‑ribulokinase/transcriptional regulator for ara operon
78,003 A→C 100%100% E128A (GAG→GCG)  yabM → putative transport protein
93,625 C→T 100%99.6% P154S (CCG→TCG)  murE → meso‑diaminopimelate‑adding enzyme
97,700 A→G 100%99.6% N205S (AAC→AGC)  murD → UDP‑N‑acetylmuramoylalanine‑D‑glutamate ligase
104,752 T→C 100%99.5% I257I (ATT→ATC ftsA → ATP‑binding cell division protein
120,509 A→G 100%98.4% V348A (GTA→GCA)  aroP ← aromatic amino acid transport protein
121,408 A→G 100%99.1% I48I (ATT→ATC aroP ← aromatic amino acid transport protein
125,440 C→T 100%99.1% F808F (TTC→TTT aceE → pyruvate dehydrogenase
126,053 T→C 100%99.1% V120A (GTG→GCG)  aceF → pyruvate dehydrogenase
129,639 A→G 100%99.2% V541A (GTG→GCG)  yacH ← putative membrane protein
130,705 C→T 100%97.5% G186S (GGC→AGC)  yacH ← putative membrane protein
140,097 A→G 100%100% W377R (TGG→CGG)  gcd ← glucose dehydrogenase
144,667 C→T 100%99.5% R31W (CGG→TGG)  yadI → putative PTS enzyme IIA component
159,448 A→G 100%98.1% V222A (GTG→GCG)  yadB ← putative tRNA synthetase
163,255 T→C 100%99.5% V399A (GTG→GCG)  hrpB → ATP‑dependent helicase
170,527 T→C 100%98.3% G250G (GGT→GGC fhuC → ATP‑binding component of hydroxymate‑dependent iron transport
172,865 C→T 50.3% A468A (GCC→GCT fhuB → FhuB
176,432 A→G 100%98.1% K442K (AAA→AAG yadQ → putative channel transporter
187,433 A→G 100%99.5% H406H (CAT→CAC glnD ← protein PII
188,442 T→C 100%98.0% Q70R (CAG→CGG)  glnD ← protein PII
200,335 A→G 100%98.7% Q803R (CAG→CGG)  yaeT → hypothetical protein
207,737 C→T 100%99.5% T871I (ACC→ATC)  dnaE → DNA polymerase III alpha subunit
258,944 A→G ?56.7% D127D (GAT→GAC phoE ← outer membrane pore protein E
260,837 A→G 100%99.5% A37A (GCA→GCG proA → gamma‑glutamylphosphate reductase
261,908 T→C 100%99.1% R394R (CGT→CGC proA → gamma‑glutamylphosphate reductase
282,839 G→A 100%99.3% A139T (GCG→ACG)  yagF → putative dehydratase
286,179 A→G 100%100% D56G (GAC→GGC)  yagH → putative beta‑xylosidase
300,714 A→G 100%98.1% L133P (CTG→CCG)  yagS ← hypothetical protein
306,757 A→G 67.0% R600R (CGT→CGC yagX ← hypothetical protein
308,315 A→G 100%100% L81P (CTG→CCG)  yagX ← hypothetical protein
312,219 T→C 59.3% intergenic (‑218/‑1362) ykgM ← / → eaeH putative ribosomal protein/attaching and effacing protein
323,547 C→T 100%99.6% A189V (GCC→GTC)  ykgG → putative transporter
337,988 C→T 100%100% P147L (CCG→CTG)  yahG → hypothetical protein
342,435 A→G 100%99.4% M110V (ATG→GTG)  yahK → putative oxidoreductase
373,904 A→G 100%98.1% R271R (CGA→CGG mhpE → 4‑hydroxy‑2‑ketovalerate aldolase
375,923 A→G 100%98.9% intergenic (+29/‑73) mhpT → / → yaiL putative transport protein/nucleoprotein/polynucleotide‑associated enzyme
405,386 C→T 100%99.5% R173R (CGC→CGT yaiI → hypothetical protein
406,582 T→C 50.5% intergenic (+188/‑70) yaiA → / → aroM hypothetical protein/aroM
418,134 T→C 100%98.3% V341A (GTA→GCA)  phoR → positive and negative sensor protein for pho regulon
419,777 C→T 100%98.4% L321L (CTC→CTT brnQ → branched chain amino acid transport system II carrier protein
421,409 T→C 54.3% G400G (GGT→GGC proY → proline permease transport protein
431,523 T→C 100%99.6% intergenic (‑286/+13) tsx ← / ← yajI Tsx/hypothetical protein
439,636 T→C 59.4% G230G (GGA→GGG ispA ← geranyltranstransferase
476,113 A→G 63.4% Y73C (TAC→TGC)  ybaA → hypothetical protein
484,670 A→G 56.3% G58G (GGT→GGC acrA ← acridine efflux pump
484,839 T→G 100%99.5% N2T (AAC→ACC)  acrA ← acridine efflux pump
502,653 C→T 100%100% intergenic (‑191/+47) ybaL ← / ← fsr putative transport protein/fosmidomycin resistance protein
513,506 A→G 100%98.9% E97G (GAG→GGG)  ybbI → putative transcriptional regulator
519,169 A→G 50.6% G71G (GGA→GGG ybbA → putative ATP‑binding component of a transport system
535,281 A→G 100%99.5% E116E (GAA→GAG gip → glyoxylate‑induced protein
540,420 A→G 100%98.2% Y211C (TAC→TGC)  ybbY → putative transport
547,694 A→G 100%100% E38E (GAA→GAG b4507 → hypothetical protein
547,835 +G 100%100% coding (255/261 nt) b4507 → hypothetical protein
559,119 T→C ?52.4% V67A (GTG→GCG)  sfmD → putative outer membrane protein
561,757 G→A 55.6% V65M (GTG→ATG)  sfmH → involved in fimbrial asembly
575,662 A→G 100%94.6% T149T (ACT→ACC nmpC ← outer membrane porin protein
588,625 A→G 100%98.5% V518A (GTA→GCA)  nfrA ← NfrA
601,951 A→G ?51.4% Y257C (TAC→TGC)  pheP → phenylalanine‑specific transport system
625,013 (C)5→4 100%97.6% coding (906/1176 nt) entC → isochorismate hydroxymutase 2
643,426 A→G 100%99.0% G267G (GGT→GGC rna ← RNase I
654,248 A→G 100%98.9% M315T (ATG→ACG)  dcuC ← DcuC
660,762 A→G 100%100% intergenic (‑161/+98) ybeF ← / ← lipB putative transcriptional regulator LYSR‑type/LipB
698,096 A→G 100%99.5% V102A (GTG→GCG)  asnB ← asparagine synthetase B
704,236 T→C 100%100% L357S (TTG→TCG)  nagE → PTS system, N‑acetylglucosamine‑specific enzyme IIABC
727,030 A→G 100%98.8% L309P (CTG→CCG)  kdpA ← KdpA
742,023 A→G 100%100% intergenic (‑244/‑27) ybgH ← / → ybgI putative transport protein/hypothetical protein
747,172 A→G 100%99.4% V345A (GTG→GCG)  ybgO ← hypothetical protein
767,322 T→C 100%98.8% L41P (CTG→CCG)  ybgG → putative sugar hydrolase
768,447 A→G 100%100% D416G (GAC→GGC)  ybgG → putative sugar hydrolase
782,054 T→C 100%98.6% A249A (GCT→GCC nadA → quinolinate synthetase A protein
783,271 A→G 63.7% V259A (GTG→GCG)  ybgR ← putative transport system permease protein
789,507 T→C 100%100% D249G (GAC→GGC)  galT ← galactose‑1‑phosphate uridylyltransferase
800,245 T→C ?52.2% D88D (GAT→GAC ybhH → hypothetical protein
842,873 A→G 52.9% W611R (TGG→CGG)  ybiO ← putative transport protein
854,026 T→C 100%100% intergenic (+38/+21) ybiR → / ← ybiS hypothetical protein/hypothetical protein
860,895 G→A 100%100% A312V (GCC→GTC)  ybiW ← putative formate acetyltransferase
865,458 C→T 54.1% V44I (GTC→ATC)  moeA ← MoeA
907,912 T→C 100%97.8% P202P (CCA→CCG ybjU ← putative arylsulfatase
908,998 A→G 100%99.4% R425R (CGT→CGC poxB ← pyruvate oxidase
926,255 A→G 100%98.5% V134A (GTC→GCC)  aat ← leucyl, phenylalanyl‑tRNA‑protein transferase
964,158 T→C 100%97.6% L206L (TTA→CTA)  ycaI → hypothetical protein
966,971 A→G 100%100% G376G (GGA→GGG msbA → ATP‑binding transport protein
967,279 T→C 100%100% V479A (GTG→GCG)  msbA → ATP‑binding transport protein
971,671 T→C 100%97.8% F233L (TTC→CTC)  b0919 → hypothetical protein
976,048 A→G 100%100% Q167R (CAG→CGG)  mukB → MukB
981,275 (G)5→6 100%99.1% coding (1006/1848 nt) ycbB → putative amidase
997,353 T→C 100%99.3% V91A (GTA→GCA)  ycbQ → putative fimbrial‑like protein
998,008 A→G 100%99.4% Y99C (TAC→TGC)  ycbR → putative chaperone
998,257 A→G 100%98.6% D182G (GAC→GGC)  ycbR → putative chaperone
1,015,360 C→T 100%97.0% V112M (GTG→ATG)  fabA ← beta‑hydroxydecanoyl thioester dehydrase
1,018,581 C→T 100%99.1% P232P (CCG→CCA ompA ← outer membrane protein 3a
1,027,127 T→C 100%99.3% intergenic (‑131/‑42) b0964 ← / → b0965 hypothetical protein/hypothetical protein
1,052,306 G→A 100%99.2% P94S (CCG→TCG)  yccM ← hypothetical protein
1,056,041 A→G 100%100% E186E (GAA→GAG torT → TorT
1,057,591 A→G 100%99.3% E95E (GAA→GAG torC → trimethylamine N‑oxide reductase, cytochrome c‑type subunit
1,063,438 T→C 100%97.8% D60D (GAT→GAC yccE → hypothetical protein
1,067,720 +C 100%98.2% intergenic (+243/+14) b4516 → / ← ycdG hypothetical protein/putative transport protein
1,070,080 T→C 100%99.0% L33L (TTA→TTG b1008 ← hypothetical protein
1,078,438 T→C 100%100% intergenic (‑333/‑90) putA ← / → putP proline dehydrogenase/major sodium/proline symporter
1,097,622 T→C 100%98.5% W185R (TGG→CGG)  ycdW → putative dehydrogenase
1,097,684 G→A 100%98.8% R205R (CGG→CGA ycdW → putative dehydrogenase
1,115,717 A→G 100%97.8% V30A (GTG→GCG)  htrB ← heat shock protein
1,125,943 A→G 64.3% L188L (TTA→TTG yceH → hypothetical protein
1,132,866 A→G 100%98.5% N357S (AAC→AGC)  flgE → hook protein
1,135,559 T→C 100%100% R22R (CGT→CGC flgI → FlgI
1,142,316 A→G 100%100% R425R (CGT→CGC rne ← RNase E
1,151,521 A→G 100%99.1% T120T (ACA→ACG fabF → 3‑oxoacyl‑[acyl‑carrier‑protein] synthase II
1,158,530 T→C 100%100% intergenic (+5/+55) ptsG → / ← fhuE PTS system, glucose‑specific IIBC component/outer membrane receptor for ferric iron uptake
1,161,046 A→G 100%99.3% intergenic (‑272/‑44) fhuE ← / → ycfF outer membrane receptor for ferric iron uptake/hypothetical protein
1,198,459 A→G 64.7% E181G (GAG→GGG)  lit → Lit
1,230,757 A→G 100%97.2% T117A (ACT→GCT)  umuC → UmuC
1,233,954 A→G 100%97.7% intergenic (‑14/‑207) nhaB ← / → fadR Na+/H+ antiporter, pH independent/FadR
1,235,811 A→G 51.5% R218R (CGT→CGC ycgB ← putative sporulation protein
1,254,408 A→G 100%99.2% S256S (AGT→AGC b1202 ← putative adhesion and penetration protein
1,256,863 A→G 100%99.1% V58A (GTA→GCA)  ychF ← putative GTP‑binding protein
1,302,782 A→G 100%100% N2S (AAC→AGC)  oppD → OppD
1,335,418 A→G 100%100% S522G (AGC→GGC)  acnA → aconitate hydrase 1
1,346,591 G→A 100%100% R116C (CGT→TGT)  rnb ← RNase II
1,368,442 C→T 100%97.8% T68I (ACA→ATA)  ycjM → putative polysaccharide hydrolase
1,373,005 A→G 100%98.9% T7A (ACA→GCA)  ycjQ → putative oxidoreductase
1,418,817 (G)6→7 100%100% coding (110/423 nt) ydaT → hypothetical protein
1,438,660 T→C 58.9% D50G (GAC→GGC)  ydbK ← putative oxidoreductase Fe‑S subunit
1,440,689 A→G 100%99.0% V60A (GTG→GCG)  ldhA ← fermentative D‑lactate dehydrogenase, NAD‑dependent
1,442,877 A→G 100%96.7% A601A (GCA→GCG ydbH → hypothetical protein
1,444,274 T→C 100%99.2% intergenic (+44/+128) ydbL → / ← feaR hypothetical protein/FeaR
1,483,110 A→G 100%97.5% T676A (ACC→GCC)  hrpA → helicase, ATP‑dependent
1,499,704 G→A 100%99.1% G40D (GGC→GAC)  tehB → TehB
1,499,997 A→G 49.5% T138A (ACC→GCC)  tehB → TehB
1,520,862 T→C ?54.3% V76V (GTA→GTG b1451 ← putative outer membrane receptor for iron transport
1,523,361 A→G 60.0% F215S (TTC→TCC)  ansP ← L‑asparagine permease
1,537,704 A→G 100%100% W971R (TGG→CGG)  narZ ← cryptic nitrate reductase 2 alpha subunit
1,542,294 A→G 100%98.4% intergenic (‑210/+114) narU ← / ← b1470 nitrite extrusion protein 2/hypothetical protein
1,548,806 T→C 100%99.0% C108R (TGC→CGC)  fdnH → formate dehydrogenase‑N, nitrate‑inducible, iron‑sulfur beta subunit
1,572,242 T→C 100%97.7% I329V (ATT→GTT)  pqqL ← putative peptidase
1,598,660 T→C 58.4% A202A (GCA→GCG ydeW ← putative transcriptional regulator, sorC family
1,599,629 T→C 100%95.7% V39A (GTC→GCC)  b1513 → putative ATP‑binding component of a transport system
1,601,638 T→C 100%97.6% L199P (CTG→CCG)  ydeY → putative transport system permease protein
1,607,710 A→G 100%100% L332P (CTT→CCT)  uxaB ← altronate oxidoreductase
1,625,295 T→C 100%99.0% Q37R (CAG→CGG)  dcp ← dipeptidyl carboxypeptidase II
1,638,567 T→C 100%100% T15A (ACA→GCA)  b1556 ← hypothetical protein
1,641,525 T→C 100%96.1% T281T (ACA→ACG b1560 ← hypothetical protein
1,650,355 T→C 100%100% F274L (TTC→CTC)  b1579 → putative transposase
1,652,626 T→C 100%100% E180E (GAA→GAG rspA ← starvation sensing protein
1,664,234 C→T 100%98.9% A319V (GCC→GTC)  b1592 → putative chloride channel
1,691,459 T→C 100%99.2% T277A (ACT→GCT)  uidB ← glucuronide permease
1,712,001 T→C 100%98.9% G403G (GGT→GGC ydgR → putative transport protein
1,717,544 T→C 100%98.9% H28R (CAC→CGC)  b1640 ← hypothetical protein
1,718,191 A→G 100%100% T98A (ACT→GCT)  slyB → putative outer membrane protein
1,722,918 T→A 100%100% N247Y (AAC→TAC)  b1647 ← hypothetical protein
1,733,771 A→G 49.4% T124A (ACC→GCC)  sodB → superoxide dismutase, iron
1,739,051 A→G 100%100% M373V (ATG→GTG)  ydhC → putative transport protein
1,741,574 2 bp→GA 100%100% coding (94‑95/1374 nt) ydhE → putative transport protein
1,786,907 A→G ?58.1% Q150R (CAG→CGG)  aroH → 3‑deoxy‑D‑arabinoheptulosonate‑7‑phosphate synthase
1,795,093 A→G 59.8% G292G (GGT→GGC pheT ← phenylalanine tRNA synthetase beta‑subunit
1,802,307 A→G 100%98.4% S397G (AGC→GGC)  b1721m → ankyrin repeat protein
1,804,677 T→C 100%99.1% V96A (GTA→GCA)  pfkB → 6‑phosphofructokinase II
1,812,482 T→C 100%100% F198L (TTC→CTC)  katE → catalase
1,843,109 C→T 57.8% A626T (GCT→ACT)  topB ← DNA topoisomerase III
1,860,370 T→C 100%100% E28E (GAA→GAG yeaA ← hypothetical protein
1,866,277 T→C 100%99.2% V449A (GTC→GCC)  yeaG → hypothetical protein
1,879,281 T→C 100%96.0% T185A (ACC→GCC)  yeaT ← putative transcriptional regulator LYSR‑type
1,881,204 T→C 100%100% intergenic (+183/‑8) yeaU → / → yeaV putative tartrate dehydrogenase/putative transport protein
1,884,815 G→A 100%100% R316H (CGC→CAC)  yeaX → putative diogenase beta subunit
1,889,990 T→A 100%95.7% S424C (AGC→TGC)  b1808 ← hypothetical protein
1,893,654 A→G 58.6% T276A (ACG→GCG)  pabB → p‑aminobenzoate synthetase component I
1,893,920 T→C 100%97.2% G364G (GGT→GGC pabB → p‑aminobenzoate synthetase component I
1,900,472 T→C 100%96.6% V134A (GTT→GCT)  manX → PTS enzyme IIAB, mannose‑specific
1,914,464 Δ1 bp 100%98.4% coding (183/1284 nt) b1833 → hypothetical protein
1,920,554 T→C 100%97.8% D147G (GAT→GGT)  b1838 ← protein phosphatase 1
1,924,467 T→C 100%96.8% P108P (CCT→CCC b1844 → hypothetical protein
1,929,521 T→C 100%100% L206P (CTG→CCG)  purT → phosphoribosylglycinamide formyltransferase 2
1,949,344 G→A 51.6% Q174Q (CAG→CAA yecD → hypothetical protein
1,953,793 T→C 100%97.7% G413G (GGA→GGG b1872 ← biotin sulfoxide reductase 2
1,963,151 A→G 100%100% A355A (GCT→GCC flhB ← FlhB
1,976,527 Δ776 bp 100% insB5insA5 insB5, insA5
1,980,940 +C 100%100% coding (1/363 nt)
coding (627/627 nt)
araH ←
araH ←
ABC‑type arabinose transport system permease component
ABC‑type arabinose transport system permease component
1,985,245 A→G 64.1% T100A (ACG→GCG)  yecI → ferritin‑like protein
1,996,614 T→C 100%99.0% D297G (GAC→GGC)  b1919 ← putative 1‑aminocyclopropane‑1‑carboxylate deaminase
2,008,480 +A 100%99.0% coding (637/654 nt) yedK → hypothetical protein
2,011,668 A→G 100%98.8% T140A (ACC→GCC)  fliF → FliF
2,012,544 A→G 100%98.2% S432G (AGT→GGT)  fliF → FliF
2,012,638 T→C 100%100% V463A (GTG→GCG)  fliF → FliF
2,043,272 A→G 100%100% S130G (AGT→GGT)  b1978 → hypothetical protein
2,070,275 G→A 56.9% G239S (GGC→AGC)  b2000 → outer membrane fluffing protein
2,072,030 T→A 100%100% C824S (TGC→AGC)  b2000 → outer membrane fluffing protein
2,072,182 T→C 63.2% G874G (GGT→GGC b2000 → outer membrane fluffing protein
2,072,384 (C)6→7 100%97.8% coding (2824/3120 nt) b2000 → outer membrane fluffing protein
2,072,439 A→G 100%100% Q960R (CAG→CGG)  b2000 → outer membrane fluffing protein
2,082,410 T→C 100%98.4% A22A (GCA→GCG yeeD ← hypothetical protein
2,084,512 A→G 100%99.0% R193R (CGT→CGC yeeF ← putative amino acid/amine transport protein
2,102,336 A→G 100%99.0% W66R (TGG→CGG)  wbbK ← putative glucose transferase
2,153,206 T→C 100%100% V439A (GTG→GCG)  b2074 → putative membrane protein
2,155,098 T→C 100%100% L605P (CTG→CCG)  yegN → hypothetical protein
2,183,895 (G)7→8 100%98.1% intergenic (‑79/‑42) yohL ← / → yohM hypothetical protein/hypothetical protein
2,197,577 T→C 100%98.9% intergenic (+3224/‑722) metG → / → yehI methionine tRNA synthetase/putative regulator
2,216,746 G→C 100%100% S252S (TCC→TCG yehZ ← putative transport system permease protein
2,225,969 A→G 57.0% S191P (TCA→CCA)  yohG ← putative channel/filament proteins
2,235,796 T→C 100%99.2% H505R (CAC→CGC)  mglA ← MglA
2,260,454 A→G 100%98.5% G354G (GGT→GGC fruB ← PTS system, fructose‑specific IIA/fpr component
2,318,226 T→C 50.3% V55A (GTC→GCC)  atoS → AtoS
2,332,579 A→G 100%98.5% L134P (CTG→CCG)  b2229 ← hypothetical protein
2,403,601 T→C 100%99.1% intergenic (‑515/+122) b2288 ← / ← lrhA NADH dehydrogenase I chain A/NADH dehydrogenase transcriptional regulator, LysR family
2,404,897 A→G 100%99.4% intergenic (‑236/‑684) lrhA ← / → b2290 NADH dehydrogenase transcriptional regulator, LysR family/putative aminotransferase
2,416,514 A→G 100%98.3% R479G (AGG→GGG)  yfcC → putative S‑transferase
2,419,101 T→C 100%97.9% L154P (CTG→CCG)  yfcG → putative S‑transferase
2,424,788 C→T 100%99.4% S7S (TCG→TCA hisJ ← histidine‑binding periplasmic protein of high‑affinity histidine transport system
2,429,483 T→C 100%100% E65E (GAA→GAG dedD ← putative lipoprotein
2,443,258 A→G 100%99.3% V108A (GTC→GCC)  yfcA ← putative structural protein
2,456,917 C→T 57.1% R88Q (CGG→CAG)  b2341 ← hypothetical protein
2,457,232 T→C 100%99.3% T420A (ACC→GCC)  b2342 ← putative acyltransferase
2,460,909 (C)9→10 74.4% intergenic (+243/‑123) fadL → / → b2345 FadL/hypothetical protein
2,462,885 T→C 100%98.1% D48G (GAC→GGC)  vacJ ← lipoprotein precursor
2,475,572 A→G 100%98.6% A26A (GCT→GCC dsdC ← D‑serine dehydratase (deaminase) transcriptional activator
2,481,497 (A)8→9 100%98.5% intergenic (‑138/‑278) emrK ← / → evgA multidrug resistance protein K/EvgA
2,487,342 T→C 58.1% T289A (ACA→GCA)  b2372 ← putative receptor protein
2,511,347 T→C 100%99.4% C96R (TGC→CGC)  nupC → NupC
2,516,832 T→C 100%98.3% intergenic (+1/‑1) yfeC → / → yfeD hypothetical protein/hypothetical protein
2,528,223 (C)5→6 100%98.4% intergenic (‑27/+44) lig ← / ← zipA DNA ligase/ZipA
2,539,912 A→G 100%100% R207R (CGT→CGC cysU ← sulfate, thiosulfate transport system permease T protein
2,547,949 T→C 100%99.2% D206G (GAC→GGC)  b2431 ← hypothetical protein
2,548,787 A→G 100%99.5% C150C (TGT→TGC b2432 ← hypothetical protein
2,551,423 T→C 100%98.6% V60A (GTC→GCC)  hemF → coproporphyrinogen III oxidase
2,555,797 G→A 100%99.2% G301G (GGC→GGT b2441 ← ethanolamine ammonia‑lyase, heavy chain
2,563,970 A→G 100%100% V312A (GTG→GCG)  b2451 ← hypothetical protein
2,567,072 T→C 100%99.3% I154V (ATT→GTT)  b2453 ← EutG
2,583,000 A→G 51.3% S182S (AGT→AGC yffG ← putative oxidoreductase Fe‑S subunit
2,606,063 T→C 100%100% M376T (ATG→ACG)  hyfF → hydrogenase 4 membrane subunit
2,620,459 G→A 100%100% R69Q (CGG→CAG)  purN → phosphoribosylglycinamide formyltransferase 1
2,622,267 T→C 100%99.4% L402L (TTA→CTA)  ppk → polyphosphate kinase
2,627,257 T→C 100%99.4% A12A (GCA→GCG b4538 ← hypothetical protein
2,627,272 A→G 60.0% G7G (GGT→GGC b4538 ← hypothetical protein
2,627,313 A→G 100%99.4% S2G (AGT→GGT)  b2504 → hypothetical protein
2,633,072 T→C 100%100% V274A (GTG→GCG)  xseA → exonuclease VII large subunit
2,636,193 A→G 50.3% G160G (GGT→GGC b2512 ← putative dehydrogenase
2,640,478 A→G 100%98.0% G129G (GGT→GGC yfgA ← putative membrane protein
2,641,750 A→G 100%100% L185P (CTG→CCG)  yfgB ← hypothetical protein
2,656,335 G→A 100%100% D207D (GAC→GAT hscA ← HscA
2,664,389 T→C 100%98.9% V319A (GTC→GCC)  csiE → hypothetical protein
2,676,851 A→G 100%100% R179R (CGT→CGC yphF ← putative LACI‑type transcriptional regulator
2,682,855 T→C 59.4% T225A (ACC→GCC)  glyA ← serine hydroxymethyltransferase
2,683,844 (A)7→8 54.4% intergenic (‑317/‑11) glyA ← / → hmpA serine hydroxymethyltransferase/dihydropteridine reductase
2,691,024 A→T 100%100% F847Y (TTT→TAT)  purL ← phosphoribosylformyl‑glycineamide synthetase
2,702,744 T→C 62.5% T196A (ACC→GCC)  lepB ← leader peptidase
2,722,352 (G)5→6 100%99.3% coding (154/273 nt) yfiM → hypothetical protein
2,723,618 T→C ?52.8% H50R (CAC→CGC)  kgtP ← alpha‑ketoglutarate permease
2,729,373 +C 100%100% intergenic (‑195/+247) rrsG ← / ← clpB 16S ribosomal RNA/ClpB
2,735,727 C→T 100%99.2% intergenic (+61/‑38) pheL → / → pheA PheL/chorismate mutase‑P
2,737,047 T→C 100%98.9% H348R (CAC→CGC)  tyrA ← chorismate mutase‑T
2,747,389 Δ1 bp 100%100% coding (572/591 nt) b4540 → hypothetical protein
2,751,091 G→C 100%100% A426P (GCT→CCT)  recN → RecN
2,754,173 A→G 100%99.4% intergenic (+774/‑7) smpB → / → intA small protein B/prophage CP4‑57 integrase
2,760,511 A→T 100%100% W351R (TGG→AGG)  yfjK ← hypothetical protein
2,766,382 C→G 100%100% P218A (CCC→GCC)  b2632 → putative GTP‑binding protein
2,766,423 G→A 100%100% R231R (CGG→CGA b2632 → putative GTP‑binding protein
2,766,427 2 bp→AC 100%100% coding (697‑698/864 nt) b2632 → putative GTP‑binding protein
2,766,473 A→G 100%100% D248G (GAT→GGT)  b2632 → putative GTP‑binding protein
2,766,475 A→G 100%100% T249A (ACC→GCC)  b2632 → putative GTP‑binding protein
2,770,753 T→C 54.8% intergenic (‑578/+104) b2638 ← / ← b4541 hypothetical protein/hypothetical protein
2,777,636 T→C ?55.6% S1081G (AGT→GGT)  ypjA ← putative ATP‑binding component of a transport system
2,781,020 +G 100%100% intergenic (‑144/+65) ypjA ← / ← b2648 putative ATP‑binding component of a transport system/hypothetical protein
2,781,027 C→G 100%100% intergenic (‑151/+58) ypjA ← / ← b2648 putative ATP‑binding component of a transport system/hypothetical protein
2,783,519 T→C 100%99.1% intergenic (+147/+263) b2651 → / ← ileY hypothetical protein/tRNA‑Ile
2,785,180 Δ1 bp 100%100% coding (413/495 nt) b2655 → hypothetical protein
2,810,863 T→C 61.3% V76A (GTC→GCC)  emrB → EmrB
2,812,859 Δ1 bp 100%100% intergenic (‑105/+46) ygaG ← / ← gshA hypothetical protein/gamma‑glutamate‑cysteine ligase
2,820,144 Δ1 bp 100%100% intergenic (+24/+18) b4542 → / ← oraA hypothetical protein/OraA
2,820,999 T→G 100%98.6% Y265S (TAC→TCC)  recA ← RecA
2,821,415 T→C 100%98.6% A126A (GCA→GCG recA ← RecA
2,823,915 A→G 100%100% K21E (AAG→GAG)  srlA → PTS system, glucitol/sorbitol‑specific IIC component
2,824,797 T→C 100%100% F128S (TTT→TCT)  srlE → PTS system glucitol/sorbitol‑specific enzyme IIBC component
2,825,102 T→C 100%100% F230L (TTC→CTC)  srlE → PTS system glucitol/sorbitol‑specific enzyme IIBC component
2,827,236 T→C 100%97.6% V56A (GTG→GCG)  srlR → SrlR
2,838,044 +G 100%100% coding (498/1458 nt) ascF → PTS system enzyme IIBC
2,838,055 Δ1 bp 100%100% coding (509/1458 nt) ascF → PTS system enzyme IIBC
2,842,033 G→T 100%100% R67R (CGC→CGA hycG ← hydrogenase activity
2,856,140 T→A 100%98.6% L342Q (CTG→CAG)  mutS → MutS
2,865,029 T→C 60.6% A182A (GCA→GCG rpoS ← sigma S factor
2,865,844 A→G 100%98.6% G311G (GGT→GGC nlpD ← lipoprotein
2,896,819 +C 100%99.5% coding (622/657 nt) ygcU ← putative oxidoreductase subunit
2,904,001 1,187,600 bp x 2 100% duplication [b2778][rhaD] 1130 genes
2,906,235 C→T 100%98.4% G485D (GGT→GAT)  pyrG ← CTP synthetase
2,939,218 G→A 100%99.5% C16C (TGC→TGT ygdE ← hypothetical protein
2,941,717 A→G 100%98.9% H120R (CAC→CGC)  b2810 → hypothetical protein
2,959,806 A→G 100%98.4% G215G (GGT→GGC recC ← RecC
2,963,192 C→T 100%98.8% V290I (GTT→ATT)  lgt ← phosphatidylglycerol‑prolipoprotein diacylglyceryl transferase
2,963,236 A→G 100%98.8% V275A (GTG→GCG)  lgt ← phosphatidylglycerol‑prolipoprotein diacylglyceryl transferase
2,972,555 A→G 100%98.7% S494S (AGT→AGC aas ← 2‑acyl‑glycerophospho‑ethanolamine acyltransferase
2,976,431 T→C 100%98.4% H164R (CAC→CGC)  lysA ← diaminopimelate decarboxylase
2,998,394 A→G 100%98.5% T10A (ACC→GCC)  b2866 → hypothetical protein
3,005,399 +C 100%100% coding (1044/1092 nt) ygeW → putative carbamoyl transferase
3,011,187 T→C 100%98.7% E358E (GAA→GAG b2875 ← putative synthases
3,015,070 T→C 100%100% G330G (GGT→GGC b2878 → putative oxidoreductase Fe‑S subunit
3,021,627 T→C 100%99.6% V764A (GTT→GCT)  b2881 → putative dehydrogenase
3,021,808 T→C 100%97.5% R824R (CGT→CGC b2881 → putative dehydrogenase
3,025,676 +C 100%100% coding (535/570 nt) ygfQ → hypothetical protein
3,026,175 A→G 100%99.2% V166V (GTA→GTG ygfR → putative oxidoreductase
3,032,764 C→T 100%98.6% R144H (CGT→CAT)  lysS ← lysine tRNA synthetase
3,036,598 A→G 58.8% V82A (GTC→GCC)  dsbC ← disulfide isomerase II
3,037,475 T→C 100%99.3% S97G (AGT→GGT)  xerD ← XerD
3,054,906 A→G 100%100% intergenic (+97/+292) b2912 → / ← serA putative ligase/D‑3‑phosphoglycerate dehydrogenase
3,058,415 A→G 100%99.6% S215G (AGC→GGC)  iciA → replication initiation inhibitor
3,059,022 T→C 60.3% G51G (GGT→GGC sbm → methylmalonyl‑CoA mutase
3,075,220 (T)5→6 100%100% coding (256/357 nt) yggP ← hypothetical protein
3,077,514 Δ1 bp 100%100% intergenic (‑165/+149) cmtB ← / ← tktA PTS system mannitol‑specific enzyme IIA component/transketolase 1 isozyme
3,077,640 +G 100%100% intergenic (‑291/+23) cmtB ← / ← tktA PTS system mannitol‑specific enzyme IIA component/transketolase 1 isozyme
3,077,905 A→G 100%100% S584P (TCG→CCG)  tktA ← transketolase 1 isozyme
3,078,245 C→G 100%100% G470G (GGG→GGC tktA ← transketolase 1 isozyme
3,084,101 T→C 100%98.8% intergenic (‑16/‑105) yqgB ← / → yqgC hypothetical protein/hypothetical protein
3,087,418 A→G 63.3% V372V (GTA→GTG galP → galactose‑proton symport of transport system
3,098,418 A→G 55.2% G110G (GGT→GGC ansB ← periplasmic L‑asparaginase II
3,099,661 (A)5→6 100%100% intergenic (‑19/+164) yggN ← / ← b2959 hypothetical protein/hypothetical protein
3,107,469 +C 100%100% intergenic (‑296/‑101) b2965 ← / → yqgA ornithine decarboxylase isozyme/putative transport protein
3,108,438 C→A 100%100% noncoding (56/76 nt) pheV → tRNA‑Phe
3,108,630 G→A 100%98.7% R172W (CGG→TGG)  yghD ← putative secretion pathway protein
3,115,116 +C 100%100% coding (2013/2028 nt) b2974 ← putative endoglucanase
3,118,108 A→G 62.0% G396G (GGT→GGC yghK ← putative permease
3,122,609 T→C 64.0% E643E (GAA→GAG glcF ← glycolate oxidase iron‑sulfur subunit
3,123,585 +G 100%100% coding (953/2286 nt) glcF ← glycolate oxidase iron‑sulfur subunit
3,127,865 T→C 100%99.2% A122A (GCA→GCG b2981 ← hypothetical protein
3,130,334 A→G 100%100% V30V (GTT→GTC b2983 ← hypothetical protein
3,152,247 +C 100%100% intergenic (+10/+29) yghB → / ← yqhC hypothetical protein/putative ARAC‑type regulatory protein
3,156,257 (CCA)2→1 100%100% coding (594‑596/930 nt) yqhG → hypothetical protein
3,158,202 +C 100%100% coding (961/975 nt) ygiRQ ← Fe‑S oxidoreductase
3,166,935 2 bp→CG 100%100% coding (312‑313/483 nt) b3023 ← hypothetical protein
3,174,443 T→C 100%100% H136R (CAC→CGC)  icc ← Icc
3,175,745 A→G 100%98.8% V61A (GTC→GCC)  yqiE ← hypothetical protein
3,179,042 T→C 100%99.6% A202A (GCT→GCC ygiC → putative synthetase/amidase
3,185,776 T→C 100%100% F121L (TTC→CTC)  yqiG → putative membrane protein
3,185,807 T→C 100%100% F131S (TTT→TCT)  yqiG → putative membrane protein
3,190,907 T→C 100%98.2% S10P (TCC→CCC)  b3051 → putative membrane protein
3,205,532 T→C 100%99.1% L174P (CTG→CCG)  ttdB → L‑tartrate dehydratase subunit B
3,208,420 A→G 100%98.6% intergenic (‑236/‑2) ygjD ← / → rpsU putative O‑sialoglycoprotein endopeptidase/30S ribosomal subunit protein S21
3,210,997 G→A 100%100% E104K (GAA→AAA)  rpoD → RNA polymerase sigma(70)
3,212,115 T→C 65.3% R476R (CGT→CGC rpoD → RNA polymerase sigma(70)
3,212,429 A→G 100%98.9% D581G (GAC→GGC)  rpoD → RNA polymerase sigma(70)
3,221,097 2 bp→GC 100%100% coding (824‑825/3093 nt) b3076 → evolved beta‑D‑galactosidase alpha subunit
3,222,944 Δ2 bp 100% coding (2671‑2672/3093 nt) b3076 → evolved beta‑D‑galactosidase alpha subunit
3,222,944 4 bp→AGCA 100% coding (2671‑2674/3093 nt) b3076 → evolved beta‑D‑galactosidase alpha subunit
3,222,948 +AC 100% coding (2675/3093 nt) b3076 → evolved beta‑D‑galactosidase alpha subunit
3,224,879 Δ1 bp 100%100% coding (1005/1434 nt) ygjI → putative oxidoreductase
3,224,926 +C 100%100% coding (1052/1434 nt) ygjI → putative oxidoreductase
3,236,177 Δ1 bp 100%100% intergenic (+239/‑45) ygjR → / → ygjT hypothetical protein/putative transport protein
3,236,735 +C 100%100% coding (514/966 nt) ygjT → putative transport protein
3,236,758 Δ1 bp 100%100% coding (537/966 nt) ygjT → putative transport protein
3,237,242 +C 100%100% intergenic (+55/‑342) ygjT → / → ygjU putative transport protein/putative transport protein
3,237,247 +C 100%100% intergenic (+60/‑337) ygjT → / → ygjU putative transport protein/putative transport protein
3,253,742 Δ1 bp 100%100% coding (551/552 nt) yhaNM ← hypothetical protein
3,255,594 Δ1 bp 100%100% coding (4/1278 nt) yhaO ← putative transport system permease protein
3,255,616 Δ1 bp 100%100% intergenic (‑19/+312) yhaO ← / ← yhaP putative transport system permease protein/putative L‑serine dehydratase
3,256,893 +C 100%100% coding (405/423 nt) yhaQ ← putative L‑serine dehydratase
3,257,838 +G 100%100% coding (2222/2241 nt) tdcE ← putative formate acetyltransferase 3
3,265,441 T→C 100%99.2% intergenic (+202/‑33) tdcR → / → yhaB threonine dehydratase operon activator protein/hypothetical protein
3,268,129 (C)7→8 100%96.2% intergenic (+661/+137) b3122 → / ← b3124 hypothetical protein/hypothetical protein
3,279,197 A→C 100%100% R145S (AGA→AGC agaA → putative N‑acetylgalactosamine‑6‑phosphate deacetylase
3,300,826 G→A 100%99.2% E239K (GAG→AAG)  yhbV → hypothetical protein
3,311,437 T→C 100%100% N740S (AAC→AGC)  infB ← protein chain initiation factor IF‑2
3,312,337 A→G 64.2% I440T (ATC→ACC)  infB ← protein chain initiation factor IF‑2
3,320,557 T→C 63.7% P385P (CCA→CCG mrsA ← MrsA
3,325,501 T→C 100%99.7% L24P (CTT→CCT)  yhbY → hypothetical protein
3,347,212 A→G 54.7% V80A (GTG→GCG)  mtgA ← putative peptidoglycan enzyme
3,349,263 (CCGGTG)1→2 100% coding (1398/2331 nt) arcB ← aerobic respiration sensor‑response protein
3,349,294 T→C 100%100% Q456R (CAG→CGG)  arcB ← aerobic respiration sensor‑response protein
3,352,254 2 bp→GC 100%100% intergenic (‑569/‑12) yhcC ← / → gltB hypothetical protein/glutamate synthase large subunit
3,359,814 T→C 100%99.7% V23A (GTT→GCT)  yhcA → putative chaperone
3,374,875 T→G 100%97.7% T61P (ACC→CCC)  sspA ← stringent starvation protein A
3,376,055 T→C 100%99.2% T78A (ACC→GCC)  rplM ← 50S ribosomal subunit protein L13
3,389,812 Δ1 bp 100%100% intergenic (‑149/+4151) tldD ← / ← cafA TldD/CafA
3,393,106 Δ1 bp 100%100% intergenic (‑3443/+857) tldD ← / ← cafA TldD/CafA
3,395,276 T→C 100%99.3% M59V (ATG→GTG)  cafA ← CafA
3,399,656 A→G 49.1% G438G (GGT→GGC yhdA ← hypothetical protein
3,418,840 +G 100%100% coding (1070/1089 nt) b3269 → putative transport system permease protein
3,419,398 (T)7→6 100%99.6% coding (441/1107 nt) yhdY → putative transport system permease protein
3,421,120 Δ1 bp 100%100% noncoding (60/121 nt) rrfF ← 5S ribosomal RNA
3,426,144 A→G 58.7% noncoding (256/1542 nt) rrsD ← 16S ribosomal RNA
3,429,527 Δ1 bp 100%100% coding (40/510 nt) yrdD ← putative DNA topoisomerase
3,430,453 +C 100%100% coding (745/747 nt) smf ← putative Rossmann‑fold nucleotide‑binding protein
3,434,252 G→A 100%98.4% G33D (GGT→GAT)  trkA → TrkA
3,438,720 T→C 100%98.5% H198R (CAC→CGC)  rpsD ← 30S ribosomal subunit protein S4
3,441,294 G→A 100%99.3% G147G (GGC→GGT prlA ← putative ATPase subunit of translocase
3,448,691 A→G 100%99.7% I104T (ATC→ACC)  rplB ← 50S ribosomal subunit protein L2
3,450,175 T→C 100%99.7% Q130R (CAG→CGG)  rplC ← 50S ribosomal subunit protein L3
3,457,218 T→C 100%98.8% C415R (TGC→CGC)  yheG → YheG
3,461,973 T→C 100%99.1% C140R (TGC→CGC)  yheK → putative export protein K
3,467,322 A→G 100%100% C57R (TGC→CGC)  yheB ← hypothetical protein
3,469,043 A→G 100%100% G703G (GGT→GGC fusA ← GTP‑binding protein chain elongation factor EF‑G
3,493,873 T→G 100%99.0% R742R (CGT→CGG nirB → nitrite reductase (NAD(P)H) subunit
3,499,227 T→C 100%100% V115A (GTA→GCA)  yhfN → putative transport protein
3,500,309 Δ1 bp 100%100% coding (333/363 nt) b3372 → hypothetical protein
3,509,958 Δ1 bp 100%100% intergenic (‑195/+314) yhfZ ← / ← trpS hypothetical protein/tryptophan tRNA synthetase
3,510,121 +G 100%100% intergenic (‑358/+151) yhfZ ← / ← trpS hypothetical protein/tryptophan tRNA synthetase
3,533,109 A→G 100%99.3% V133A (GTC→GCC)  envZ ← protein histidine kinase
3,537,405 +GC 100%100% intergenic (+61/‑394) b3407 → / → feoA hypothetical protein/ferrous iron transport protein A
3,544,357 +G 100%100% coding (163/1314 nt) gntT → gluconate permease
3,544,360 +G 100%100% coding (166/1314 nt) gntT → gluconate permease
3,544,363 +C 100%100% coding (169/1314 nt) gntT → gluconate permease
3,548,005 C→T 100%100% G701D (GGT→GAT)  malP ← maltodextrin phosphorylase
3,553,975 C→T 100%98.9% E171K (GAA→AAA)  yhgKJ ← RNA phosphage cyclase
3,554,088 +C 100%100% coding (2/624 nt) yhgKJ ← RNA phosphage cyclase
3,554,113 Δ1 bp 100%100% coding (372/396 nt) yhgKJ ← RNA phosphage cyclase
3,554,118 +C 100%100% coding (367/396 nt) yhgKJ ← RNA phosphage cyclase
3,556,855 A→G 100%100% Q319R (CAG→CGG)  rtcR → putative 2‑component regulator
3,558,932 2 bp→GC 100%100% coding (153‑154/831 nt) glpG ← GlpG
3,561,412 A→G 100%98.4% V76A (GTG→GCG)  b3427 ← hypothetical protein
3,562,795 G→A 100%98.6% L474L (CTG→TTG)  glgP ← glycogen phosphorylase
3,573,700 +C 100%100% intergenic (+403/+997) yhgN → / ← gntK hypothetical protein/gluconokinase 2
3,575,446 +G 100%100% coding (912/942 nt) gntR ← GntR
3,588,160 A→G 100%99.0% F128S (TTC→TCC)  ugpA ← UgpA
3,591,480 T→C 100%99.7% T120A (ACG→GCG)  livG ← ATP‑binding component of high‑affinity branched‑chain amino acid transport system
3,602,257 A→G 100%99.4% A78A (GCA→GCG yhhF → hypothetical protein
3,610,376 T→C 100%99.1% V294A (GTG→GCG)  b3474 → hypothetical protein
3,627,142 +G 100%100% intergenic (‑24/+23) yhiH ← / ← yhiI putative ATP‑binding component of a transport system, fragment 1/putative membrane protein
3,635,956 G→A 58.5% D229N (GAT→AAT)  pitA → low‑affinity phosphate transport
3,652,629 A→G 100%100% Y106C (TAC→TGC)  yhiF → hypothetical protein
3,675,983 T→C 100%99.4% T5A (ACG→GCG)  yhjG ← hypothetical protein
3,682,392 A→G 58.5% V275A (GTG→GCG)  yhjK ← hypothetical protein
3,686,775 +T 100%100% intergenic (‑23/+9) b3530 ← / ← yhjM putative oxidoreductase subunit/putative endoglucanase
3,700,934 T→C 100%99.4% T182A (ACC→GCC)  dppD ← putative ATP‑binding component of dipeptide transport system
3,703,602 2 bp→GC 100%100% intergenic (‑183/+124) dppB ← / ← dppA dipeptide transport system permease protein 1/dipeptide transport protein
3,703,857 A→G 100%99.3% V493A (GTG→GCG)  dppA ← dipeptide transport protein
3,707,653 A→G 100%98.8% L162P (CTG→CCG)  yhjW ← hypothetical protein
3,714,436 2 bp→GC 100%100% coding (261‑262/660 nt) yiaD → putative outer membrane protein
3,720,144 T→C 58.9% Y628C (TAC→TGC)  glyS ← glycine tRNA synthetase beta subunit
3,730,028 G→A 100%99.6% G67R (GGA→AGA)  xylG → putative ATP‑binding protein of xylose transport system
3,734,264 2 bp→GC 100%100% coding (542‑543/825 nt) bax ← putative ATP‑binding protein
3,737,956 2 bp→CG 100%100% coding (623‑624/1254 nt) avtA → alanine‑alpha‑ketoisovalerate transaminase
3,743,603 Δ1 bp 100%100% coding (1171/1275 nt) yiaN → putative membrane protein
3,754,310 C→A 100%100% R382M (AGG→ATG)  yiaY ← putative oxidoreductase
3,754,317 +GCG 100%100% coding (1138/1149 nt) yiaY ← putative oxidoreductase
3,765,203 A→T 100%100% Q119L (CAG→CTG)  yibJ → hypothetical protein
3,765,234 G→A 100%100% G129G (GGG→GGA yibJ → hypothetical protein
3,781,277 A→G 100%99.7% R4R (CGT→CGC gpsA ← glycerol‑3‑phosphate dehydrogenase (NAD+)
3,784,235 A→G 100%99.7% Q450R (CAG→CGG)  yibO → putative 2,3‑bisphosphoglycerate‑independent phosphoglycerate mutase
3,787,205 (C)5→6 100%98.5% coding (504/1035 nt) yibD ← putative regulator
3,791,003 T→C 100%99.5% E108G (GAG→GGG)  htrL ← HtrL
3,799,097 T→C 100%99.8% Q177R (CAG→CGG)  rfaJ ← UDP‑D‑glucose:(galactosyl)lipopolysaccharide glucosyltransferase
3,814,781 T→A 100%99.8% L160Q (CTG→CAG)  yicC → putative alpha helix protein
3,815,047 T→C 100%99.2% F249L (TTC→CTC)  yicC → putative alpha helix protein
3,823,345 C→T 58.0% A170V (GCG→GTG)  recG → DNA helicase
3,838,716 A→G 58.9% G272G (GGT→GGC yicM ← putative transport protein
3,850,157 T→C 56.1% G85G (GGA→GGG ilvB ← acetolactate synthase I large subunit
3,851,179 T→C 100%99.1% intergenic (‑564/‑364) ivbL ← / → emrD ilvB operon leader peptide/2‑module integral membrane pump
3,852,805 C→T 53.2% R145Q (CGG→CAG)  yidF ← putative transcriptional regulator
3,853,675 A→G 100%99.7% L87P (CTG→CCG)  yidH ← hypothetical protein
3,855,776 G→A 100%99.2% R86C (CGC→TGC)  yidJ ← putative sulfatase
3,870,631 Δ1 bp 100%100% coding (610/1764 nt) dgoA ← 2‑oxo‑3‑deoxygalactonate 6‑phosphate aldolase
3,870,765 +G 100%100% coding (476/1764 nt) dgoA ← 2‑oxo‑3‑deoxygalactonate 6‑phosphate aldolase
3,870,876 Δ1 bp 100%100% coding (365/1764 nt) dgoA ← 2‑oxo‑3‑deoxygalactonate 6‑phosphate aldolase
3,872,450 +G 100%100% coding (338/387 nt) yidW ← regulator protein for dgo operon
3,873,025 A→G 100%99.6% intergenic (‑238/‑97) yidW ← / → yidX regulator protein for dgo operon/putative replicase
3,873,627 Δ1 bp 100%100% coding (506/672 nt) yidX → putative replicase
3,876,595 G→C 100%100% P385A (CCG→GCG)  gyrB ← DNA gyrase subunit B
3,879,829 T→C 100%99.3% T41A (ACG→GCG)  dnaN ← DNA polymerase III beta‑subunit
3,881,483 Δ1 bp 100%100% intergenic (‑126/‑482) dnaA ← / → rpmH DnaA/50S ribosomal subunit protein L34
3,885,848 T→C 55.6% intergenic (+27/‑216) thdF → / → tnaL GTP‑binding protein in thiophene and furan oxidation/tryptophanase leader peptide
3,886,421 T→C 57.6% R21R (CGT→CGC b3708 → tryptophanase
3,896,324 +G 100%100% coding (698/711 nt) b3718 ← putative isomerase
3,908,031 T→C 100%99.8% intergenic (‑5/+82) pstC ← / ← pstS PstC/PstS
3,919,891 G→A 100%99.7% R64C (CGT→TGT)  atpI ← membrane‑bound ATP synthase
3,923,716 A→G 56.5% I123T (ATC→ACC)  mioC ← MioC
3,926,344 G→A 100%99.0% H240H (CAC→CAT yieM ← hypothetical protein
3,927,062 +G 100%100% coding (2/1284 nt)
coding (169/183 nt)
yieM ←
b4564 ←
hypothetical protein
hypothetical protein
3,930,457 Δ1 bp 100%100% coding (1515/1560 nt) kup → low affinity potassium transport system
3,930,568 +G 100%100% intergenic (+66/‑373) kup → / → rbsD low affinity potassium transport system/RbsD
3,930,677 +G 100%100% intergenic (+175/‑264) kup → / → rbsD low affinity potassium transport system/RbsD
3,936,574 C→T 100%99.4% A241V (GCC→GTC)  rbsR → RbsR
3,938,138 A→G 53.3% L34S (TTA→TCA)  yieO ← putative transport protein
3,938,587 +TGC 100%100% coding (220/546 nt) yiePs ← hypothetical protein
3,941,734 A→G 100%100% noncoding (409/2906 nt) rrlC → 23S ribosomal RNA
3,941,738 A→G 100%100% noncoding (413/2906 nt) rrlC → 23S ribosomal RNA
3,944,244 C→A 100% intergenic (+13/‑80) rrlC → / → rrfC 23S ribosomal RNA/5S ribosomal RNA
3,944,676 2 bp→GC 100%100% intergenic (+20/+75) trpT → / ← yifDA tRNA‑Trp/transcription regulator
3,945,079 A→G 100%98.9% S171S (AGT→AGC yifDA ← transcription regulator
3,945,351 +C 100%100% coding (1/600 nt)
coding (240/240 nt)
yifDA ←
yifDA ←
transcription regulator
transcription regulator
3,948,864 A→G 57.6% T228A (ACC→GCC)  ilvG → acetolactate synthase II large subunit
3,950,557 2 bp→GC 100%100% coding (451‑452/930 nt) ilvE → branched‑chain amino‑acid aminotransferase
3,951,166 +C 100%100% coding (35/1818 nt) ilvD → dihydroxyacid dehydratase
3,951,168 +G 100%100% coding (37/1818 nt) ilvD → dihydroxyacid dehydratase
3,957,092 +CC 100%100% intergenic (+26/+58) ilvC → / ← ppiC ketol‑acid reductoisomerase/peptidyl‑prolyl cis‑trans isomerase C
3,957,124 +G 100%100% intergenic (+58/+26) ilvC → / ← ppiC ketol‑acid reductoisomerase/peptidyl‑prolyl cis‑trans isomerase C
3,957,547 2 bp→GG 100% intergenic (‑116/‑744) ppiC ← / → rep peptidyl‑prolyl cis‑trans isomerase C/rep helicase
3,957,548 1 bp→GG 100% intergenic (‑117/‑744) ppiC ← / → rep peptidyl‑prolyl cis‑trans isomerase C/rep helicase
3,957,551 +T 100%100% intergenic (‑120/‑741) ppiC ← / → rep peptidyl‑prolyl cis‑trans isomerase C/rep helicase
3,957,560 +C 100%99.7% intergenic (‑129/‑732) ppiC ← / → rep peptidyl‑prolyl cis‑trans isomerase C/rep helicase
3,958,877 2 bp→CG 100%100% coding (586‑587/2022 nt) rep → rep helicase
3,960,578 2 bp→CG 100%100% coding (1266‑1267/1485 nt) gppA ← guanosine pentaphosphatase
3,961,588 C→G 100%100% R86T (AGG→ACG)  gppA ← guanosine pentaphosphatase
3,964,819 T→A 100%99.7% L263Q (CTG→CAG)  rho → transcription termination factor Rho
3,967,647 (G)6→7 51.5% coding (1005/1050 nt) wzzE → putative transport protein
3,968,317 +CGT 100%100% coding (612/1170 nt) wecB → UDP‑N‑acetyl glucosamine ‑2‑epimerase
3,969,103 2 bp→GC 100%100% coding (232‑233/1263 nt) wecC → UDP‑N‑acetyl‑D‑mannosaminuronic acid dehydrogenase
3,971,075 2 bp→GC 100%100% coding (942‑943/1068 nt) rffG → dTDP‑glucose 4,6‑dehydratase
3,972,637 2 bp→GC 100%100% coding (430‑431/546 nt) wecD → hypothetical protein
3,973,752 A→G 100%99.3% H332R (CAC→CGC)  wecE → putative regulator
3,975,313 Δ1 bp 100%100% intergenic (+173/‑901) wzxE → / → wecF putative cytochrome/TDP‑Fuc4NAc:lipidII transferase
3,976,922 A→G ?52.2% I237V (ATT→GTT)  wecF → TDP‑Fuc4NAc:lipidII transferase
3,978,702 C→T 100%100% S68F (TCC→TTC)  yifK → putative amino acid/amine transport protein
3,979,535 +G 100%100% coding (1036/1386 nt) yifK → putative amino acid/amine transport protein
3,979,546 Δ1 bp 100%100% coding (1047/1386 nt) yifK → putative amino acid/amine transport protein
3,980,297 (C)8→9 100%93.8% noncoding (79/87 nt) leuT → tRNA‑Leu
3,980,918 2 bp→CG 100%100% coding (348‑349/1236 nt) aslB → putative arylsulfatase regulator
3,987,546 A→G 100%99.0% G285G (GGT→GGC hemC ← porphobilinogen deaminase
3,987,586 2 bp→GC 100%100% coding (814‑815/963 nt) hemC ← porphobilinogen deaminase
3,987,822 2 bp→CG 100%100% coding (578‑579/963 nt) hemC ← porphobilinogen deaminase
3,989,493 A→G 100%98.7% Y243C (TAC→TGC)  cyaA → adenylate cyclase
3,990,760 T→C 100%99.2% R665R (CGT→CGC cyaA → adenylate cyclase
3,997,520 A→G 100%99.6% E642G (GAA→GGA)  uvrD → DNA‑dependent ATPase I and helicase II
3,998,290 +G 100%99.7% coding (379/486 nt) b4566 ← hypothetical protein
4,001,421 2 bp→GC 100%100% coding (381‑382/903 nt) rarD ← hypothetical protein
4,001,486 2 bp→GC 100%100% coding (316‑317/903 nt) rarD ← hypothetical protein
4,001,717 +C 100%100% coding (86/903 nt) rarD ← hypothetical protein
4,004,979 +G 100%100% coding (1511/1833 nt) recQ → ATP‑dependent DNA helicase
4,004,984 +CG 100%100% coding (1516/1833 nt) recQ → ATP‑dependent DNA helicase
4,005,601 +C 100%100% coding (237/282 nt) b4568 → hypothetical protein
4,006,483 +C 100%100% coding (183/207 nt) b4554 ← hypothetical protein
4,007,320 A→G 52.2% N182S (AAC→AGC)  pldB → lysophospholipase L(2)
4,007,718 2 bp→CG 100%100% coding (943‑944/1023 nt) pldB → lysophospholipase L(2)
4,007,907 +GG 100%100% intergenic (+109/‑11) pldB → / → b4555 lysophospholipase L(2)/hypothetical protein
4,008,375 +A 100%100% coding (458/516 nt) b4555 → hypothetical protein
4,008,391 +C 100%100% coding (474/516 nt) b4555 → hypothetical protein
4,008,393 C→G 100%100% A159G (GCT→GGT)  b4555 → hypothetical protein
4,008,398 5 bp→5 bp 100% coding (481‑485/516 nt) b4555 → hypothetical protein
4,008,400 +GAAA 100% coding (483/516 nt) b4555 → hypothetical protein
4,008,404 +G 100% coding (487/516 nt) b4555 → hypothetical protein
4,008,411 +C 100%100% coding (494/516 nt) b4555 → hypothetical protein
4,008,421 +T 100%100% coding (504/516 nt) b4555 → hypothetical protein
4,008,429 +TG 100%98.6% coding (512/516 nt) b4555 → hypothetical protein
4,008,469 +G 100%100% intergenic (+36/‑197) b4555 → / → yigM hypothetical protein/hypothetical protein
4,008,473 +G 100%100% intergenic (+40/‑193) b4555 → / → yigM hypothetical protein/hypothetical protein
4,008,491 2 bp→CG 100%100% intergenic (+58/‑174) b4555 → / → yigM hypothetical protein/hypothetical protein
4,008,525 +G 100%100% intergenic (+92/‑141) b4555 → / → yigM hypothetical protein/hypothetical protein
4,013,176 C→G 100% G182R (GGA→CGA)  ysgA ← hypothetical protein
4,013,176 2 bp→GC 100% coding (543‑544/999 nt) ysgA ← hypothetical protein
4,013,177 +C 100% coding (543/999 nt) ysgA ← hypothetical protein
4,013,717 +G 100%100% coding (3/999 nt) ysgA ← hypothetical protein
4,013,772 +C 100%100% intergenic (‑53/‑246) ysgA ← / → udp hypothetical protein/uridine phosphorylase
4,016,743 C→T 100%100% P101L (CCC→CTC)  ubiE → UbiE
4,019,857 C→T 100%100% intergenic (+56/‑28) b3836 → / → b3838 hypothetical protein/hypothetical protein
4,019,860 Δ2 bp 100%100% intergenic (+59/‑24) b3836 → / → b3838 hypothetical protein/hypothetical protein
4,021,684 Δ1 bp 100%100% coding (542/609 nt)|coding (1/243 nt) b4556 →
tatD →
hypothetical protein
Mg‑dependent DNase
4,023,045 G→A 67.2% A156A (GCG→GCA yigC → putative oxidoreductase
4,024,435 A→G 100%99.0% I107V (ATT→GTT)  ubiB → ferrisiderophore reductase
4,026,252 2 bp→GC 100%100% coding (110‑111/1164 nt) fadA ← thiolase I
4,030,374 T→C 100%99.6% V98A (GTG→GCG)  b3848 → hypothetical protein
4,031,984 +C 100%100% coding (1250/1299 nt) trkH → TrkH
4,034,652 C→T 53.5% noncoding (1533/1542 nt) rrsA → 16S ribosomal RNA
4,039,960 Δ1 bp 100%100% intergenic (+42/‑36) yihD → / → yihE hypothetical protein/hypothetical protein
4,041,126 A→G 100%99.1% E43G (GAG→GGG)  dsbA → protein disulfide isomerase I
4,041,654 G→A 100%100% intergenic (+29/‑125) dsbA → / → b3861 protein disulfide isomerase I/putative GTP‑binding protein
4,041,671 (T)6→7 100%100% intergenic (+46/‑108) dsbA → / → b3861 protein disulfide isomerase I/putative GTP‑binding protein
4,051,144 Δ1 bp 100%100% intergenic (+146/+305) hemN → / ← glnG O2‑independent coproporphyrinogen III oxidase/GlnG
4,051,170 +C 100%100% intergenic (+172/+279) hemN → / ← glnG O2‑independent coproporphyrinogen III oxidase/GlnG
4,057,759 +C 100%100% coding (1773/1776 nt) yihK → putative GTP‑binding factor
4,061,961 Δ1 bp 100%100% coding (1386/1458 nt) b3876 ← putative permease
4,062,416 A→G 65.2% W311R (TGG→CGG)  b3876 ← putative permease
4,065,486 A→G 100%99.6% G457G (GGT→GGC yihQ ← putative glycosidase
4,069,524 A→G 58.4% R236R (CGT→CGC yihT ← putative aldolase
4,070,656 T→C 100%100% M166V (ATG→GTG)  yihU ← putative dehydrogenase
4,080,993 T→C 100%99.3% T804A (ACT→GCT)  fdoG ← formate dehydrogenase‑O, major subunit
4,083,016 C→T 100%98.7% A129A (GCG→GCA
A129A (GCG→GCA
fdoG ←
b4557 ←
formate dehydrogenase‑O, major subunit
hypothetical protein
4,085,675 Δ1 bp 100%100% intergenic (+38/+13) yiiG → / ← frvR hypothetical protein/putative frv operon regulatory protein
4,091,351 C→T 100%100% G168D (GGC→GAC)  rhaD ← rhamnulose‑phosphate aldolase
4,091,572 3461 bp→29 bp 100% [rhaD]rhaB [rhaD], rhaA, rhaB
4,095,001 544,300 bp x 2 100% duplication [rhaB]lasT 507 genes
4,103,519 +T 100%100% intergenic (‑268/‑530) cpxR ← / → yiiP transcriptional regulator in 2‑component system/putative transport system permease protein
4,111,822 T→C 100%98.7% P77P (CCA→CCG fpr ← ferredoxin‑NADP reductase
4,139,669 +C 100%100% coding (233/330 nt)
coding (132/159 nt)
yijI →
b4558 ←
hypothetical protein
hypothetical protein
4,146,144 T→C ?54.4% T567T (ACA→ACG yijP ← hypothetical protein
4,149,965 A→G 100%100% V238A (GTC→GCC)  ppc ← phosphoenolpyruvate carboxylase
4,154,554 Δ1 bp 100%98.2% coding (126/1374 nt) argH → argininosuccinate lyase
4,158,827 G→T 100%99.7% G61V (GGC→GTC)  yijC → hypothetical protein
4,161,702 C→G 100%100% A162G (GCA→GGA)  btuB → BtuB
4,172,702 A→G 100%100% intergenic (‑97/+90) coaA ← / ← b3975 pantothenate kinase/hypothetical protein
4,175,949 +G 100%100% intergenic (+82/‑76) nusG → / → rplK NusG/50S ribosomal subunit protein L11
4,177,348 A→G 100%99.1% intergenic (+187/‑226) rplA → / → rplJ 50S ribosomal subunit protein L1/50S ribosomal subunit protein L10
4,182,613 A→G 56.8% Q1264R (CAG→CGG)  rpoB → RNA polymerase beta subunit
4,185,074 A→T 100%99.3% Q716L (CAG→CTG)  rpoC → RNA polymerase beta prime subunit
4,193,274 A→G 50.9% V135A (GTA→GCA)  thiC ← ThiC
4,194,577 2 bp→GC 100%100% coding (97‑98/774 nt) yjaD → hypothetical protein
4,201,880 A→G 100%99.1% Q328R (CAG→CGG)  hydG → HydG
4,215,575 A→G 100%100% E296E (GAA→GAG aceA → isocitrate lyase
4,222,792 C→T 100%99.6% G462G (GGC→GGT metH → B12‑dependent homocysteine‑N5‑methyltetrahydrofolate transmethylase
4,230,115 A→G 67.9% V233A (GTA→GCA)  lysC ← aspartokinase III
4,253,662 C→T 100%99.6% M128I (ATG→ATA plsB ← glycerol‑3‑phosphate acyltransferase
4,266,879 A→G 72.3% intergenic (+993/‑114) tyrB → / → aphA tyrosine aminotransferase/diadenosine tetraphosphatase
4,272,173 A→G 100%98.8% Q157R (CAG→CGG)  ssb → ssDNA‑binding protein
4,276,490 A→G 100%100% T145A (ACG→GCG)  yjcD → hypothetical protein
4,280,469 T→C 100%100% I62M (ATA→ATG yjcF ← hypothetical protein
4,281,296 C→T 100%98.3% A396T (GCG→ACG)  yjcG ← putative transport protein
4,293,960 +GC 100% intergenic (+587/+55) gltP → / ← yjcO glutamate‑aspartate symport protein/hypothetical protein
4,295,081 T→C 100%99.2% D622G (GAT→GGT)  fdhF ← selenopolypeptide subunit of formate dehydrogenase H
4,302,330 A→G 100%99.3% V620A (GTG→GCG)  yjcS ← hypothetical protein
4,311,496 +C 100%100% coding (301/408 nt) phnQ ← hypothetical protein
4,316,203 T→A 100%100% Q47L (CAG→CTG)  phnK ← ATP‑binding component of phosphonate transport
4,326,590 A→G 100%99.0% G626G (GGA→GGG yjdA → putative vimentin
4,337,864 A→G 100%100% L80P (CTT→CCT)  adiA ← biodegradative arginine decarboxylase
4,355,838 T→C 100%99.7% T120A (ACC→GCC)  cadA ← lysine decarboxylase 1
4,364,726 T→C 57.7% I394V (ATC→GTC)  b4139 ← aspartate ammonia‑lyase
4,384,262 T→C 56.3% E896G (GAG→GGG)  yjeP ← putative periplasmic binding protein
4,426,466 T→C 66.8% intergenic (‑135/‑47) ytfB ← / → b4207 hypothetical protein/FKBP‑type 22KD peptidyl‑prolyl cis‑trans isomerase (rotamase)
4,435,684 +A 100%100% coding (400/501 nt) ytfI → hypothetical protein
4,437,156 A→G 53.8% E11G (GAG→GGG)  ytfK → hypothetical protein
4,439,829 T→C 100%98.8% intergenic (‑76/‑130) msrA ← / → ytfM peptide methionine sulfoxide reductase/hypothetical protein
4,441,820 A→G 100%99.5% P44P (CCA→CCG ytfN → hypothetical protein
4,448,541 +C 100% intergenic (+46/‑92) ytfQ → / → ytfR putative LACI‑type transcriptional regulator/YtfR
4,448,541 2 bp→CC 100% intergenic (+46/‑91) ytfQ → / → ytfR putative LACI‑type transcriptional regulator/YtfR
4,448,543 +C 100% intergenic (+48/‑90) ytfQ → / → ytfR putative LACI‑type transcriptional regulator/YtfR
4,449,738 +G 100%100% coding (1106/1254 nt) ytfR → YtfR
4,472,408 A→G 100%100% intergenic (+117/‑28) b4251 → / → b4252 hypothetical protein/hypothetical protein
4,474,826 +A 100%100% intergenic (+1/+44) yjgL → / ← argI hypothetical protein/ornithine carbamoyltransferase 1
4,474,848 +GTATTT 100% intergenic (+23/+22) yjgL → / ← argI hypothetical protein/ornithine carbamoyltransferase 1
4,474,849 20 bp→30 bp 100% intergenic (+24/+2) yjgL → / ← argI hypothetical protein/ornithine carbamoyltransferase 1
4,474,850 +CG ?100% intergenic (+25/+20) yjgL → / ← argI hypothetical protein/ornithine carbamoyltransferase 1
4,474,857 +T ?100% intergenic (+32/+13) yjgL → / ← argI hypothetical protein/ornithine carbamoyltransferase 1
4,474,866 Δ1 bp ?100% intergenic (+41/+4) yjgL → / ← argI hypothetical protein/ornithine carbamoyltransferase 1
4,474,868 +CA 100% intergenic (+43/+2) yjgL → / ← argI hypothetical protein/ornithine carbamoyltransferase 1
4,477,041 Δ1 bp 100%100% intergenic (‑151/‑269) b4256 ← / → yjgN hypothetical protein/hypothetical protein
4,477,068 +C 100%100% intergenic (‑178/‑242) b4256 ← / → yjgN hypothetical protein/hypothetical protein
4,477,281 Δ1 bp 100%100% intergenic (‑391/‑29) b4256 ← / → yjgN hypothetical protein/hypothetical protein
4,477,321 Δ1 bp 100%100% coding (12/1182 nt) yjgN → hypothetical protein
4,478,503 (A)7→6 100%100% intergenic (+12/+47) yjgN → / ← valS hypothetical protein/valine tRNA synthetase
4,478,511 Δ1 bp 100%100% intergenic (+20/+39) yjgN → / ← valS hypothetical protein/valine tRNA synthetase
4,478,527 Δ1 bp 100%100% intergenic (+36/+23) yjgN → / ← valS hypothetical protein/valine tRNA synthetase
4,484,334 A→G 100%100% A183A (GCA→GCG yjgP → hypothetical protein
4,500,500 A→G 100%99.2% V167A (GTC→GCC)  yi41 ← IS4 hypothetical protein
4,525,836 T→C 100%98.7% N217S (AAC→AGC)  sgcQ ← putative nucleoside triphosphatase
4,529,882 A→G 52.4% intergenic (‑663/+123) sgcX ← / ← yjhP putative lyase/synthase/putative methyltransferase
4,542,643 Δ1 bp 100%100% intergenic (+46/‑22) b4316 → / → fimD Pil/FimD
4,543,743 T→C ?52.6% V360A (GTA→GCA)  fimD → FimD
4,544,170 T→C 100%100% I502I (ATT→ATC fimD → FimD
4,550,462 A→G 100%98.8% intergenic (+73/‑8) uxuA → / → uxuB mannonate hydrolase/D‑mannonate oxidoreductase
4,557,351 T→C 100%97.4% L73L (TTA→TTG yjiG ← hypothetical protein
4,562,252 A→G 100%99.1% Y5H (TAT→CAT)  yjiL ← hypothetical protein
4,573,190 Δ1 bp 100%100% coding (1487/1542 nt) yjiU → hypothetical protein
4,574,258 A→G 100%97.5% M355V (ATG→GTG)  mcrD → McrD
4,583,050 G→A 100%100% Q446* (CAA→TAA)  hsdR ← endonuclease R
4,593,254 2 bp→GC 100%100% coding (59‑60/807 nt) yjjM ← hypothetical protein
4,593,336 +G 100%100% intergenic (‑23/‑208) yjjM ← / → yjjN hypothetical protein/putative oxidoreductase
4,600,078 C→T 100%100% W135* (TGG→TAG)  yjjP ← putative structural protein
4,608,595 2 bp→GC 100%100% intergenic (+23/‑369) prfC → / → osmY peptide chain release factor RF‑3/OsmY
4,614,238 G→T 100%100% L133I (CTA→ATA)  yjjI ← hypothetical protein
4,620,440 T→C 100%98.6% M368T (ATG→ACG)  yjjJ → hypothetical protein