breseq  version 0.35.4  revision f352f80f4bc9
mutation predictions | marginal predictions | summary statistics | genome diff | command line log

Predicted mutations
evidence position mutation freq annotation gene description
RA 7,429 G→T 6.0% P177P (CCC→CCA yaaJ ← putative transporter
RA 11,196 C→A 10.6% G54V (GGG→GTG)  yaaW ← UPF0174 family protein
RA 35,095 G→T 6.6% R93S (CGC→AGC)  caiE ← stimulator of CaiD and CaiB enzyme activities
RA 46,184 C→A 6.5% I126I (ATC→ATA yaaU → putative transporter
RA 92,012 C→A 7.9% L292L (CTC→CTA murF → UDP‑N‑acetylmuramoyl‑tripeptide:D‑alanyl‑D‑ alanine ligase
RA 110,358 C→A 10.4% A143E (GCG→GAG)  guaC → GMP reductase
RA 154,273 C→T 6.3% P447P (CCG→CCA pcnB ← poly(A) polymerase
RA 155,718 G→T 6.8% P294P (CCC→CCA gluQ ← glutamyl‑Q tRNA(Asp) synthetase
RA 163,514 G→T 5.1% M766I (ATG→ATT mrcB → fused glycosyl transferase and transpeptidase
RA 166,083 G→A 10.0% A705T (GCT→ACT)  fhuA → ferrichrome outer membrane transporter
RA 175,172 C→A 6.6% G157C (GGT→TGT)  mtn ← 5'‑methylthioadenosine/S‑adenosylhomocysteine nucleosidase
RA 221,373:1 +G 9.3% noncoding (1116/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,380 T→A 9.8% noncoding (1123/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,390 Δ1 bp 9.9% noncoding (1133/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,391 G→A 9.9% noncoding (1134/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,393 C→T 10.2% noncoding (1136/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,395 G→A 10.1% noncoding (1138/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,397 C→T 10.0% noncoding (1140/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,398 C→T 10.0% noncoding (1141/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,402 A→C 10.1% noncoding (1145/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,407 A→T 10.6% noncoding (1150/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,412 A→T 10.7% noncoding (1155/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,420 A→G 11.1% noncoding (1163/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,425 T→C 17.0% noncoding (1168/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,430 T→C 17.2% noncoding (1173/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,455 G→A 23.5% noncoding (1198/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,464 G→C 19.0% noncoding (1207/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,471 C→T 21.1% noncoding (1214/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 221,476 A→T 23.5% noncoding (1219/1542 nt) rrsH → 16S ribosomal RNA of rrnH operon
RA 256,630 G→T 5.9% D178Y (GAC→TAC)  proB → gamma‑glutamate kinase
RA 262,526 C→T 6.0% pseudogene (153/192 nt) ykfK ← CP4‑6 prophage; putative DNA‑binding transcriptional regulator;Phage or Prophage Related
RA 262,529 C→T 6.1% pseudogene (150/192 nt) ykfK ← CP4‑6 prophage; putative DNA‑binding transcriptional regulator;Phage or Prophage Related
RA 262,683 C→G 5.4% intergenic (‑5/+212) ykfK ← / ← yafZ CP4‑6 prophage; putative DNA‑binding transcriptional regulator;Phage or Prophage Related/CP4‑6 prophage; conserved protein
RA 262,684 G→A 5.3% intergenic (‑6/+211) ykfK ← / ← yafZ CP4‑6 prophage; putative DNA‑binding transcriptional regulator;Phage or Prophage Related/CP4‑6 prophage; conserved protein
RA 262,691 G→A 6.2% intergenic (‑13/+204) ykfK ← / ← yafZ CP4‑6 prophage; putative DNA‑binding transcriptional regulator;Phage or Prophage Related/CP4‑6 prophage; conserved protein
RA 262,692 T→G 6.1% intergenic (‑14/+203) ykfK ← / ← yafZ CP4‑6 prophage; putative DNA‑binding transcriptional regulator;Phage or Prophage Related/CP4‑6 prophage; conserved protein
RA 264,376 G→A 5.5% A99V (GCT→GTT)  ykfA ← CP4‑6 prophage; putative GTP‑binding protein
RA 274,938 T→A 8.4% Q152L (CAG→CTG)  insB1 ← IS1 transposase B
RA 291,686 A→G 8.2% I374I (ATT→ATC intF ← CP4‑6 prophage; putative phage integrase
RA 314,740 G→A 5.8% R325W (CGG→TGG)  rclA ← reactive chlorine stress species (RCS) resistance protein; pyridine nucleotide‑dependent disulfide oxidoreductase family
RA 318,153 G→T 8.9% G35G (GGG→GGT ykgF → ferridoxin‑like LutB family protein; putative electron transport chain YkgEFG component
RA 328,782 C→A 10.3% T234K (ACG→AAG)  yahA → c‑di‑GMP‑specific phosphodiesterase
RA 345,428 T→C 12.2% intergenic (+145/‑295) prpB → / → prpC 2‑methylisocitrate lyase/2‑methylcitrate synthase
RA 363,721 C→T 5.9% A293V (GCG→GTG)  mhpA → 3‑(3‑hydroxyphenyl)propionate hydroxylase
RA 378,487 G→T 11.7% P302Q (CCG→CAG)  yaiP ← putative family 2 glycosyltransferase
RA 406,905 C→A 7.5% G345C (GGT→TGT)  araJ ← arabinose‑inducible putative transporter, MFS family
RA 409,292 C→A 6.1% E640* (GAA→TAA)  sbcC ← exonuclease, dsDNA, ATP‑dependent
RA 418,751 G→T 7.5% D260Y (GAC→TAC)  malZ → maltodextrin glucosidase
RA 419,830 G→A 6.8% P182L (CCG→CTG)  acpH ← acyl carrier protein (ACP) phosphodiesterase; ACP hydrolyase
RA 441,908 G→T 9.6% S72Y (TCC→TAC)  yajR ← putative transporter
RA 453,420 T→C 7.5% I180T (ATT→ACT)  clpX → ATPase and specificity subunit of ClpX‑ClpP ATP‑dependent serine protease
RA 484,979 G→T 11.7% L996F (TTG→TTT mscK → mechanosensitive channel protein, intermediate conductance, K+ regulated
RA 502,930 C→A 6.3% A203S (GCA→TCA)  ybaP ← TraB family protein
RA 519,919 G→A 6.7% E401E (GAG→GAA rhsD → Rhs family putative polymorphic toxin
RA 522,248 A→C 7.7% S1178R (AGC→CGC)  rhsD → Rhs family putative polymorphic toxin
RA 541,563 C→A 8.9% G86V (GGA→GTA)  allD ← ureidoglycolate dehydrogenase
RA 561,384 C→A 6.8% P17P (CCG→CCT
pseudogene (152/222 nt)
intD ←
xisD ←
DLP12 prophage; putative phage integrase
pseudogene, exisionase in defective prophage DLP12;Phage or Prophage Related
RA 603,459 G→T 10.8% intergenic (+15/‑62) hokE → / → insL1 toxic polypeptide, small/IS186 transposase
RA 603,460 T→A 7.7% intergenic (+16/‑61) hokE → / → insL1 toxic polypeptide, small/IS186 transposase
RA 603,462 A→T 6.4% intergenic (+18/‑59) hokE → / → insL1 toxic polypeptide, small/IS186 transposase
RA 615,146 G→T 6.8% P170P (CCC→CCA fepC ← iron‑enterobactin transporter subunit
RA 625,648 G→A 9.5% G100D (GGT→GAT)  cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 625,650:1 +A 9.3% coding (301/2106 nt) cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 625,650:2 +A 9.3% coding (301/2106 nt) cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 625,652 G→T 9.3% P101P (CCG→CCT cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 625,654:1 +C 10.8% coding (305/2106 nt) cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 625,656 G→C 10.8% V103L (GTG→CTG) ‡ cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 625,657 T→C 10.8% V103A (GTG→GCG) ‡ cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 625,659 G→T 11.2% G104W (GGG→TGG)  cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 625,662 C→A 10.6% P105T (CCG→ACG) ‡ cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 625,663 C→T 11.3% P105L (CCG→CTG) ‡ cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 625,666 T→G 9.8% V106G (GTA→GGA)  cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 640,282 C→A 9.1% D60Y (GAT→TAT)  rna ← ribonuclease I
RA 661,951 T→A 5.2% T575S (ACC→TCC)  mrdA ← transpeptidase involved in peptidoglycan synthesis (penicillin‑binding protein 2)
RA 679,468 A→G 7.5% L134P (CTC→CCC)  rihA ← ribonucleoside hydrolase 1
RA 694,866 G→A 7.4% intergenic (‑233/+164) asnB ← / ← umpH asparagine synthetase B/UMP phosphatase
RA 694,871 A→C 16.7% intergenic (‑238/+159) asnB ← / ← umpH asparagine synthetase B/UMP phosphatase
RA 700,566 G→T 6.6% L389L (CTG→CTT nagE → fused N‑acetyl glucosamine specific PTS enzyme: IIC, IIB, and IIA components
RA 711,705 C→A 8.0% pseudogene (349/651 nt) ybfG ← pseudogene
RA 713,401 C→A 7.7% A107A (GCG→GCT potE ← putrescine/proton symporter: putrescine/ornithine antiporter
RA 716,701 C→A 8.3% L163L (CTG→CTT kdpE ← response regulator in two‑component regulatory system with KdpD
RA 726,319 G→C 6.3% A427A (GCG→GCC rhsC → Rhs family putative polymorphic toxin
RA 727,989 C→A 7.4% A984E (GCA→GAA)  rhsC → Rhs family putative polymorphic toxin
RA 733,384 C→G 9.1% pseudogene (1104/1137 nt) ybfL → pseudogene, DDE domain transposase family;putative factor; Not classified; putative receptor protein
RA 746,059 C→A 6.4% G523C (GGT→TGT)  ybgQ ← putative outer membrane protein
RA 789,497 G→T 7.8% Q202K (CAA→AAA)  modE ← transcriptional repressor for the molybdenum transport operon modABC
RA 806,474 G→T 9.5% G213V (GGG→GTG)  bioF → 8‑amino‑7‑oxononanoate synthase
RA 818,333 G→T 7.2% P288Q (CCG→CAG)  clsB ← cardiolipin synthase 2
RA 824,502 G→T 5.8% T309T (ACC→ACA ybhG ← putative membrane fusion protein (MFP) component of efflux pump, membrane anchor
RA 835,110 G→T 9.4% P626P (CCC→CCA fiu ← catecholate siderophore receptor Fiu
RA 838,535 T→A 6.6% F250I (TTT→ATT)  rlmF → 23S rRNA m(6)A1618 methyltransferase, SAM‑dependent
RA 840,709 G→T 8.8% P76P (CCC→CCA ybiO ← mechanosensitive channel protein, intermediate conductance
RA 896,076 G→T 7.7% intergenic (‑45/+246) artJ ← / ← artM arginine binding protein, periplasmic/arginine transporter subunit
RA 903,673 G→T 15.4% L22L (CTC→CTA ybjT ← putative NAD‑dependent oxidoreductase
RA 904,751 G→T 6.3% intergenic (‑1/+36) ltaE ← / ← poxB L‑allo‑threonine aldolase, PLP‑dependent/pyruvate dehydrogenase (pyruvate oxidase), thiamine triphosphate‑binding, FAD‑binding
RA 905,041 G→T 9.3% R489S (CGC→AGC)  poxB ← pyruvate dehydrogenase (pyruvate oxidase), thiamine triphosphate‑binding, FAD‑binding
RA 913,167 G→T 6.6% E413D (GAG→GAT ybjD → putative OLD family ATP‑dependent endonuclease; DUF2813 family protein
RA 931,040 A→G 10.8% P787P (CCA→CCG ftsK → DNA translocase at septal ring sorting daughter chromsomes
RA 931,045 A→C 12.1% Q789P (CAG→CCG) ‡ ftsK → DNA translocase at septal ring sorting daughter chromsomes
RA 931,046 G→A 12.1% Q789Q (CAG→CAA) ‡ ftsK → DNA translocase at septal ring sorting daughter chromsomes
RA 937,215 G→T 6.7% M267I (ATG→ATT dmsA → dimethyl sulfoxide reductase, anaerobic, subunit A
RA 942,562 C→A 7.6% intergenic (+87/‑123) ycaD → / → ycaM putative MFS‑type transporter/putative transporter
RA 955,888 T→A 15.4% C57S (TGT→AGT) ‡ ycaL → putative peptidase‑related chaperone
RA 955,890 T→C 15.4% C57C (TGT→TGC) ‡ ycaL → putative peptidase‑related chaperone
RA 966,575 G→A 9.7% D90N (GAC→AAC)  kdsB → 3‑deoxy‑manno‑octulosonate cytidylyltransferase
RA 969,233 C→A 7.3% R81S (CGC→AGC)  smtA → putative S‑adenosyl‑L‑methionine‑dependent methyltransferase
RA 1,008,116 G→A 12.7% G220G (GGG→GGA pqiA → paraquat‑inducible, SoxRS‑regulated inner membrane protein
RA 1,042,761 G→T 8.7% P214Q (CCG→CAG)  gfcD ← putative O‑antigen capsule production periplasmic protein
RA 1,052,241 C→A 6.6% P175P (CCC→CCA torT → periplasmic sensory protein associated with the TorRS two‑component regulatory system
RA 1,072,820 G→T 6.8% Q507K (CAG→AAG)  putA ← fused DNA‑binding transcriptional regulator/proline dehydrogenase/pyrroline‑5‑carboxylate dehydrogenase
RA 1,079,245 G→T 7.5% V138V (GTG→GTT efeB → deferrrochelatase, periplasmic
RA 1,091,136 G→T 15.8% pseudogene (176/342 nt) ymdE → pseudogene
RA 1,096,068 G→T 6.6% G106V (GGG→GTG)  ycdZ → DUF1097 family inner membrane protein
RA 1,122,072 C→A 7.0% R154S (CGC→AGC)  yceH → UPF0502 family protein
RA 1,123,723 G→T 7.0% L143L (CTG→CTT murJ → putative peptidoglycan lipid II flippase
RA 1,172,640 G→T 15.8% G189V (GGG→GTG)  lolD → outer membrane‑specific lipoprotein transporter subunit
RA 1,177,019 G→T 14.8% H55N (CAT→AAT)  ymfA ← DUF3592 family inner membrane protein
RA 1,200,837 G→T 8.2% pseudogene (978/1134 nt) aaaE → pseudogene, phage terminase protein A family, e14 prophage;Phage or Prophage Related
RA 1,218,978 C→T 6.5% intergenic (+73/‑42) ymgJ → / → ycgI uncharacterized protein/pseudogene
RA 1,255,456 G→T 6.8% F268L (TTC→TTA dauA ← C4‑dicarboxylic acid transporter
RA 1,256,841 G→T 11.3% P164Q (CCA→CAA)  prs ← phosphoribosylpyrophosphate synthase
RA 1,264,970 G→A 8.0% intergenic (+125/+189) rdlA → / ← ldrB sRNA antisense regulator affects LdrA translation; proposed addiction module in LDR‑A repeat, with toxic peptide LdrA/toxic polypeptide, small
RA 1,266,001 G→T 7.5% intergenic (+85/+204) rdlC → / ← chaA sRNA antisense regulator affects LdrC translation; proposed addiction module in LDR‑C repeat, with toxic peptide LdrC/calcium/sodium:proton antiporter
RA 1,273,396 G→T 10.5% intergenic (‑322/‑17) narX ← / → narK sensory histidine kinase in two‑component regulatory system with NarL/nitrate/nitrite transporter
RA 1,282,243 G→A 5.7% intergenic (+261/+279) narI → / ← rttR nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript
RA 1,282,249 A→G 6.9% intergenic (+267/+273) narI → / ← rttR nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript
RA 1,282,287 T→A 8.9% intergenic (+305/+235) narI → / ← rttR nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript
RA 1,282,439 A→G 5.1% intergenic (+457/+83) narI → / ← rttR nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript
RA 1,282,497 A→G 8.8% intergenic (+515/+25) narI → / ← rttR nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript
RA 1,287,985 C→A 8.3% D132Y (GAT→TAT)  hns ← global DNA‑binding transcriptional dual regulator H‑NS
RA 1,303,847 C→A 12.1% G227V (GGG→GTG)  kch ← voltage‑gated potassium channel
RA 1,310,804 C→A 9.6% A226S (GCA→TCA)  trpA ← tryptophan synthase, alpha subunit
RA 1,322,685 C→A 6.9% G229C (GGC→TGC)  yciK ← putative EmrKY‑TolC system oxoacyl‑(acyl carrier protein) reductase
RA 1,323,392 C→A 7.0% intergenic (‑23/‑197) yciK ← / → sohB putative EmrKY‑TolC system oxoacyl‑(acyl carrier protein) reductase/inner membrane protein, S49 peptidase family protein
RA 1,329,553 C→A 12.0% V2V (GTC→GTA yciX → uncharacterized protein
RA 1,336,774 T→C 5.9% G199G (GGT→GGC pyrF → orotidine‑5'‑phosphate decarboxylase
RA 1,336,783 C→G 6.2% R202R (CGC→CGG pyrF → orotidine‑5'‑phosphate decarboxylase
RA 1,336,786:1 +G 6.2% coding (609/738 nt) pyrF → orotidine‑5'‑phosphate decarboxylase
RA 1,336,789 T→G 5.7% I204M (ATT→ATG pyrF → orotidine‑5'‑phosphate decarboxylase
RA 1,336,790 A→G 5.8% M205V (ATG→GTG) ‡ pyrF → orotidine‑5'‑phosphate decarboxylase
RA 1,336,791 T→A 5.9% M205K (ATG→AAG) ‡ pyrF → orotidine‑5'‑phosphate decarboxylase
RA 1,336,793 A→C 5.9% T206P (ACG→CCG)  pyrF → orotidine‑5'‑phosphate decarboxylase
RA 1,340,543 C→A 7.4% G153W (GGG→TGG)  gmr ← cyclic‑di‑GMP phosphodiesterase; csgD regulator; modulator of Rnase II stability
RA 1,343,979 G→T 7.8% T129K (ACG→AAG)  yciW ← putative oxidoreductase
RA 1,345,091 G→A 6.9% A69V (GCC→GTC)  fabI ← enoyl‑[acyl‑carrier‑protein] reductase, NADH‑dependent
RA 1,355,323 G→T 13.7% intergenic (‑158/‑54) puuA ← / → puuD glutamate‑‑putrescine ligase/gamma‑glutamyl‑gamma‑aminobutyrate hydrolase
RA 1,370,455 G→T 11.8% V55V (GTG→GTT ycjR → putative TIM alpha/beta barrel enzyme
RA 1,373,074 G→T 14.8% D312Y (GAC→TAC)  ycjT → putative family 65 glycosyl hydrolase
RA 1,374,200 G→T 10.8% W687L (TGG→TTG)  ycjT → putative family 65 glycosyl hydrolase
RA 1,378,247 G→T 8.7% intergenic (‑29/‑127) ycjW ← / → ycjX LacI family putative transcriptional repressor/DUF463 family protein, putative P‑loop NTPase
RA 1,392,933 C→A 12.5% intergenic (‑54/+98) uspE ← / ← fnr stress‑induced protein/oxygen‑sensing anaerobic growth regulon transcriptional regulator; autorepressor
RA 1,402,792 C→A 9.8% I162I (ATC→ATA ydaN → putative Zn(II) transporter
RA 1,422,040 A→G 15.2% pseudogene (944/981 nt) insH1 ← IS5 transposase and trans‑activator;IS, phage, Tn; Transposon‑related functions; extrachromosomal; transposon related
RA 1,422,060 G→C 15.4% pseudogene (924/981 nt) insH1 ← IS5 transposase and trans‑activator;IS, phage, Tn; Transposon‑related functions; extrachromosomal; transposon related
RA 1,422,627 A→G 5.5% pseudogene (357/981 nt) insH1 ← IS5 transposase and trans‑activator;IS, phage, Tn; Transposon‑related functions; extrachromosomal; transposon related
RA 1,460,689 A→G 10.4% pseudogene (1041/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,470,314 C→T 12.9% A305V (GCG→GTG)  ydbD → PF10971 family putative periplasmic methylglyoxal resistance protein
RA 1,475,967 G→T 8.7% G268W (GGG→TGG)  ynbD → putative phosphatase inner membrane protein
RA 1,491,925 G→T 11.4% Q271H (CAG→CAT opgD → osmoregulated periplasmic glucan (OPG) biosynthesis periplasmic protein
RA 1,493,541 C→A 9.8% A116E (GCA→GAA)  rimL → ribosomal‑protein‑L7/L12‑serine acetyltransferase
RA 1,522,194 C→T 5.9% pseudogene (36/2037 nt) rhsE → pseudogene, Rhs family protein
RA 1,522,197 G→T 5.9% pseudogene (39/2037 nt) rhsE → pseudogene, Rhs family protein
RA 1,522,198 T→G 6.3% pseudogene (40/2037 nt) rhsE → pseudogene, Rhs family protein
RA 1,522,200 G→C 5.6% pseudogene (42/2037 nt) rhsE → pseudogene, Rhs family protein
RA 1,522,209 C→T 5.8% pseudogene (51/2037 nt) rhsE → pseudogene, Rhs family protein
RA 1,526,840 G→A 8.0% G256G (GGG→GGA ydcC → H repeat‑associated putative transposase
RA 1,535,454 C→T 12.5% G465D (GGC→GAC)  narZ ← nitrate reductase 2 (NRZ), alpha subunit
RA 1,551,840 G→T 10.9% A152A (GCC→GCA ddpF ← D,D‑dipeptide permease system, ATP‑binding component
RA 1,567,028 G→A 6.3% S811L (TCG→TTG)  pqqL ← putative periplasmic M16 family zinc metalloendopeptidase
RA 1,582,366 G→T 7.7% S63Y (TCT→TAT)  ydeR ← putative fimbrial‑like adhesin protein
RA 1,585,098 C→A 9.1% intergenic (‑305/+13) yneL ← / ← hipA pseudogene, AraC family/inactivating GltX kinase facilitating persister formation; toxin of HipAB TA pair; autokinase
RA 1,590,935 G→T 10.6% pseudogene (1310/5323 nt) yneO ← pseudogene, AidA homolog
RA 1,619,903 G→A 8.3% R579W (CGG→TGG)  dcp ← dipeptidyl carboxypeptidase II
RA 1,631,894 C→A 14.8% S49I (AGC→ATC)  gnsB ← Qin prophage; multicopy suppressor of secG(Cs) and fabA6(Ts)
RA 1,650,950 G→T 12.5% L170L (CTG→CTT speG → spermidine N1‑acetyltransferase
RA 1,672,825 G→T 17.3% A48S (GCT→TCT)  ydgH → DUF1471 family periplasmic protein
RA 1,703,023 C→A 8.3% V616V (GTC→GTA rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,705,492 G→T 13.4% M136I (ATG→ATT rsxE → SoxR iron‑sulfur cluster reduction factor component; electron transport inner membrane NADH‑quinone reductase
RA 1,712,178 G→T 7.3% A29A (GCC→GCA pdxH ← pyridoxine 5'‑phosphate oxidase
RA 1,718,730 G→T 9.6% P61P (CCC→CCA sodC ← superoxide dismutase, Cu, Zn, periplasmic
RA 1,736,118 C→A 20.0% S150Y (TCT→TAT)  cfa → cyclopropane fatty acyl phospholipid synthase (unsaturated‑phospholipid methyltransferase)
RA 1,752,675 G→T 6.8% A103E (GCA→GAA)  ldtE ← murein L,D‑transpeptidase
RA 1,754,720 C→A 9.1% G21C (GGT→TGT)  sufS ← cysteine desulfurase, stimulated by SufE; selenocysteine lyase, PLP‑dependent
RA 1,836,334 G→A 9.6% P20L (CCG→CTG)  ynjH ← DUF1496 family protein
RA 1,861,910 G→A 5.7% G249D (GGT→GAT)  yeaG → protein kinase, endogenous substrate unidentified; autokinase
RA 1,869,494 A→G 10.2% L114L (TTA→CTA)  yeaM ← putative DNA‑binding transcriptional regulator
RA 1,875,411 G→T 7.5% T219N (ACC→AAC)  dmlR ← transcriptional activator of dmlA
RA 1,893,055 G→T 9.9% L124L (CTG→CTT yoaD → putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase, regulator of cellulose production
RA 1,928,247 C→A 6.7% M205I (ATG→ATT edd ← 6‑phosphogluconate dehydratase
RA 1,938,665 C→A 18.1% G317W (GGG→TGG)  ruvB ← ATP‑dependent DNA helicase, component of RuvABC resolvasome
RA 1,946,755 G→A 8.4% G78D (GGC→GAC)  yecN → MAPEG family inner membrane protein
RA 1,958,199 C→A 10.0% R370L (CGA→CTA)  flhA ← putative flagellar export pore protein
RA 2,015,868 C→A 13.4% A173A (GCC→GCA fliP → flagellar biosynthesis protein
RA 2,031,801 G→T 6.2% P168P (CCC→CCA yedW ← response regulator family protein
RA 2,056,551 Δ1 bp 6.1% coding (254/933 nt) ldtA ← L,D‑transpeptidase linking Lpp to murein
RA 2,056,552 Δ1 bp 6.1% coding (253/933 nt) ldtA ← L,D‑transpeptidase linking Lpp to murein
RA 2,056,553 Δ1 bp 6.1% coding (252/933 nt) ldtA ← L,D‑transpeptidase linking Lpp to murein
RA 2,056,554 Δ1 bp 6.1% coding (251/933 nt) ldtA ← L,D‑transpeptidase linking Lpp to murein
RA 2,056,555 Δ1 bp 6.1% coding (250/933 nt) ldtA ← L,D‑transpeptidase linking Lpp to murein
RA 2,067,892 G→T 7.4% W958L (TGG→TTG)  flu → CP4‑44 prophage; antigen 43 (Ag43) phase‑variable biofilm formation autotransporter
RA 2,073,088 C→A 7.9% V329L (GTG→TTG)  yeeA ← putative transporter, FUSC family inner membrane protein
RA 2,074,677 C→T 5.3% E23K (GAA→AAA)  sbmC ← DNA gyrase inhibitor
RA 2,097,794 C→A 23.6% W66L (TGG→TTG)  wbbK ← lipopolysaccharide biosynthesis protein
RA 2,112,339 G→T 8.3% A434E (GCG→GAG)  wzxC ← putative colanic acid exporter
RA 2,119,512 C→T 7.4% R64R (CGG→CGA wcaH ← GDP‑mannose mannosyl hydrolase
RA 2,121,436 G→T 10.8% L120L (CTC→CTA gmd ← GDP‑D‑mannose dehydratase, NAD(P)‑binding
RA 2,122,185 G→T 11.5% P62Q (CCG→CAG)  wcaF ← putative acyl transferase
RA 2,147,724 C→A 8.4% L76L (CTC→CTA mdtA → multidrug efflux system, subunit A
RA 2,199,283 C→T 5.8% P37L (CCG→CTG)  yehM → uncharacterized protein
RA 2,199,438 G→T 6.7% A89S (GCC→TCC)  yehM → uncharacterized protein
RA 2,224,091 G→A 8.3% intergenic (‑227/‑12) dusC ← / → yohJ tRNA‑dihydrouridine synthase C/UPF0299 family inner membrane protein
RA 2,241,133 C→T 5.1% L293L (CTG→CTA lysP ← lysine transporter
RA 2,250,111 G→T 10.5% S235* (TCG→TAG)  psuT ← putative nucleoside transporter
RA 2,278,730 C→A 5.4% F292L (TTC→TTA yejM → essential inner membrane DUF3413 domain‑containing protein; lipid A production and membrane permeability factor
RA 2,286,111 C→A 5.4% K111N (AAG→AAT dsbE ← periplasmic thioredoxin of cytochrome c‑type biogenesis
RA 2,299,422 G→A 11.8% A271V (GCG→GTG)  mqo ← malate dehydrogenase, FAD/NAD(P)‑binding domain
RA 2,307,218 C→A 13.1% P84P (CCC→CCA rcsD → phosphotransfer intermediate protein in two‑component regulatory system with RcsBC
RA 2,311,679 C→T 9.3% L559L (CTG→CTA rcsC ← hybrid sensory kinase in two‑component regulatory system with RcsB and YojN
RA 2,312,340 C→A 10.8% R339L (CGA→CTA)  rcsC ← hybrid sensory kinase in two‑component regulatory system with RcsB and YojN
RA 2,316,985 C→A 12.1% T20T (ACC→ACA atoD → acetyl‑CoA:acetoacetyl‑CoA transferase, alpha subunit
RA 2,327,125 C→T 7.0% pseudogene (757/4605 nt) yfaS ← pseudogene, bacterial alpha2‑macroglobulin YfaS variant family; putative membrane protein
RA 2,341,502 G→T 8.3% A214S (GCT→TCT)  nrdB → ribonucleoside‑diphosphate reductase 1, beta subunit, ferritin‑like protein
RA 2,350,805 C→T 6.0% D141D (GAC→GAT yfaD → transposase_31 family protein
RA 2,366,237 C→A 11.2% P68T (CCG→ACG)  arnE → undecaprenyl phosphate‑alpha‑L‑ara4N exporter; flippase ArnEF subunit
RA 2,384,069 G→T 8.7% L306I (CTC→ATC)  nuoN ← NADH:ubiquinone oxidoreductase, membrane subunit N
RA 2,398,475 A→G 8.2% L26P (CTG→CCG)  nuoA ← NADH:ubiquinone oxidoreductase, membrane subunit A
RA 2,428,083 C→T 8.3% T46T (ACG→ACA dedA ← DedA family inner membrane protein
RA 2,428,712 C→A 5.3% G135V (GGG→GTG)  truA ← tRNA pseudouridine(38‑40) synthase
RA 2,450,091 C→A 6.5% L67L (CTG→CTT sixA ← phosphohistidine phosphatase
RA 2,464,459 G→T 5.5% pseudogene (166/291 nt) tfaS → pseudogene, CPS‑53 (KpLE1) prophage; tail fiber assembly protein fragment;Phage or Prophage Related
RA 2,482,029 C→A 7.4% A207S (GCC→TCC)  yfdE ← acetyl‑CoA:oxalate CoA‑transferase
RA 2,507,777 G→A 8.3% intergenic (+54/‑33) nupC → / → insL1 nucleoside (except guanosine) transporter/IS186 transposase
RA 2,524,388 G→T 13.0% H69N (CAC→AAC)  zipA ← FtsZ stabilizer
RA 2,548,797 G→T 13.1% P97P (CCC→CCA eutK ← putative ethanol utilization carboxysome structural protein
RA 2,571,155 G→A 5.8% G194G (GGC→GGT maeB ← malic enzyme: putative oxidoreductase/putative phosphotransacetylase
RA 2,575,814 C→A 19.3% W108L (TGG→TTG)  ypfG ← DUF1176 family protein
RA 2,588,749 G→A 11.1% P157L (CCA→CTA)  tmcA ← elongator methionine tRNA (ac4C34) acetyltransferase
RA 2,594,490 Δ1 bp 6.2% intergenic (+183/‑70) bcp → / → hyfA peroxiredoxin; thiol peroxidase, thioredoxin‑dependent/hydrogenase 4, 4Fe‑4S subunit
RA 2,597,916 G→T 6.6% V237V (GTG→GTT hyfC → hydrogenase 4, membrane subunit
RA 2,603,514 G→T 9.1% intergenic (+1/‑9) hyfG → / → hyfH hydrogenase 4, subunit/hydrogenase 4, Fe‑S subunit
RA 2,618,622 G→A 6.7% G50D (GGC→GAC)  ppx → exopolyphosphatase
RA 2,633,102 G→T 6.8% S278Y (TCC→TAC)  hisS ← histidyl tRNA synthetase
RA 2,652,183 T→A 7.8% S38C (AGC→TGC)  hscA ← DnaK‑like molecular chaperone specific for IscU
RA 2,653,960 C→A 7.4% E311* (GAG→TAG)  iscS ← cysteine desulfurase (tRNA sulfurtransferase), PLP‑dependent
RA 2,662,776 C→A 9.7% P129Q (CCA→CAA)  hcaE → 3‑phenylpropionate dioxygenase, large (alpha) subunit
RA 2,667,655 G→T 7.8% L131L (CTC→CTA yphB ← mutarotase superfamily protein, YphB family
RA 2,668,853 C→A 7.4% D90Y (GAC→TAC)  yphC ← putative Zn‑dependent NAD(P)‑binding oxidoreductase
RA 2,668,994 C→T 5.7% D43N (GAT→AAT)  yphC ← putative Zn‑dependent NAD(P)‑binding oxidoreductase
RA 2,671,727 C→A 14.3% intergenic (‑7/+16) yphE ← / ← yphF putative sugar transporter subunit of ABC superfamily, ATP‑binding component/putative ABC superfamily sugar transporter periplasmic‑binding protein
RA 2,682,560 T→A 6.0% Q102H (CAA→CAT yfhG ← putative outer membrane protein modulating the QseEF response
RA 2,705,502 C→T 6.1% A208T (GCA→ACA)  trmN ← tRNA1(Val) (adenine(37)‑N6)‑methyltransferase
RA 2,706,533 C→A 13.6% S93S (TCC→TCA srmB → ATP‑dependent RNA helicase
RA 2,706,653 G→T 13.1% T133T (ACG→ACT srmB → ATP‑dependent RNA helicase
RA 2,707,697 C→G 6.6% intergenic (+108/+101) srmB → / ← yfiE ATP‑dependent RNA helicase/putative DNA‑binding transcriptional regulator
RA 2,707,699 C→A 7.0% intergenic (+110/+99) srmB → / ← yfiE ATP‑dependent RNA helicase/putative DNA‑binding transcriptional regulator
RA 2,707,702 T→A 7.3% intergenic (+113/+96) srmB → / ← yfiE ATP‑dependent RNA helicase/putative DNA‑binding transcriptional regulator
RA 2,707,703 C→T 7.3% intergenic (+114/+95) srmB → / ← yfiE ATP‑dependent RNA helicase/putative DNA‑binding transcriptional regulator
RA 2,726,753 T→C 6.1% K260K (AAA→AAG clpB ← protein disaggregation chaperone
RA 2,762,053 T→A 7.7% A10A (GCT→GCA yfjQ → CP4‑57 prophage; uncharacterized protein
RA 2,762,059 T→C 7.7% N12N (AAT→AAC yfjQ → CP4‑57 prophage; uncharacterized protein
RA 2,793,615 C→T 5.3% S37S (AGC→AGT ygaM → DUF883 family protein, putative membrane‑anchored ribosome‑binding protein
RA 2,800,456 C→T 7.4% intergenic (+23/‑35) proW → / → proX glycine betaine transporter subunit/glycine betaine transporter subunit
RA 2,809,333 G→T 10.5% P156T (CCA→ACA)  gshA ← glutamate‑cysteine ligase
RA 2,830,666 C→A 8.9% C40F (TGT→TTT)  hypF ← carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases
RA 2,830,850 C→A 10.1% intergenic (‑66/+87) hypF ← / ← hydN carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases/formate dehydrogenase‑H, [4Fe‑4S] ferredoxin subunit
RA 2,836,035 G→T 15.5% P123Q (CCG→CAG)  hycI ← protease involved in processing C‑terminal end of HycE
RA 2,841,555 C→T 9.5% R349H (CGT→CAT)  hycC ← hydrogenase 3, membrane subunit
RA 2,863,294 G→T 6.2% R114S (CGT→AGT)  umpG ← broad specificity 5'(3')‑nucleotidase and polyphosphatase
RA 2,874,305 C→A 10.9% G35W (GGG→TGG)  casD ← CRISP RNA (crRNA) containing Cascade antiviral complex protein
RA 2,894,141 C→A 7.8% P64H (CCC→CAC)  yqcE → MFS transporter family protein
RA 2,903,483 C→A 8.6% A188S (GCT→TCT)  mazG ← nucleoside triphosphate pyrophosphohydrolase
RA 2,941,012 G→A 13.3% noncoding (47/77 nt) metV → tRNA‑Met
RA 2,946,517 G→A 9.7% A949V (GCG→GTG)  recB ← exonuclease V (RecBCD complex), beta subunit
RA 2,966,555 C→A 9.3% V223L (GTG→TTG)  lplT ← lysophospholipid transporter
RA 2,977,481 C→T 7.1% M1V (GTG→GTA) † kduI ← hexuronate isomerase; hexuronate utilization in high osmolarity
RA 2,999,606 C→A 7.9% intergenic (‑461/‑15) ygeV ← / → ygeW putative sigma‑54‑interacting transcriptional activator/putative carbamoyltransferase
RA 3,005,767 G→T 16.5% intergenic (+15/+206) yqeA → / ← yqeB putative amino acid kinase/XdhC‑CoxI family protein with NAD(P)‑binding Rossman fold
RA 3,011,777 G→T 6.6% E787* (GAA→TAA)  ygfK → putative Fe‑S subunit oxidoreductase subunit
RA 3,021,200 C→A 7.2% L241M (CTG→ATG)  ygfQ → putative purine permease
RA 3,030,927 C→T 6.2% R180H (CGC→CAC)  recJ ← ssDNA exonuclease, 5' ‑‑> 3'‑specific
RA 3,036,448 G→A 18.2% S20S (AGC→AGT yqfA ← hemolysin III family HylIII inner membrane protein
RA 3,064,718 T→G 12.3% intergenic (‑115/+100) fbaA ← / ← pgk fructose‑bisphosphate aldolase, class II/phosphoglycerate kinase
RA 3,065,586 C→A 7.4% L132L (CTG→CTT pgk ← phosphoglycerate kinase
RA 3,087,155 C→T 8.1% S99S (AGC→AGT yqgF → putative Holliday junction resolvase
RA 3,111,338 G→T 10.1% P378P (CCC→CCA yghJ ← DUF4092 family putative lipoprotein peptidase
RA 3,198,382 C→A 8.0% T110T (ACC→ACA plsY → putative glycerol‑3‑phosphate acyltransferase
RA 3,237,226 C→A 9.1% W292L (TGG→TTG)  uxaC ← uronate isomerase
RA 3,241,190 C→A 6.0% A20D (GCC→GAC)  yqjA → general envelope maintenance protein; DedA family inner membrane protein
RA 3,287,349 C→A 8.5% D197E (GAC→GAA lpoA → OM lipoprotein stimulator of MrcA transpeptidase
RA 3,295,392 G→T 6.9% T183T (ACG→ACT yhbU → U32 peptidase family protein
RA 3,323,297 C→A 6.8% P326T (CCT→ACT)  dacB → D‑alanyl‑D‑alanine carboxypeptidase
RA 3,324,747 G→T 6.2% H123N (CAC→AAC)  obgE ← GTPase involved in cell partioning and DNA repair
RA 3,327,511 T→G 8.8% L148R (CTG→CGG)  ispB → octaprenyl diphosphate synthase
RA 3,330,767 G→A 7.7% Q162* (CAG→TAG)  mlaC ← ABC transporter maintaining OM lipid asymmetry, periplasmic binding protein
RA 3,350,633 G→A 6.1% P850P (CCG→CCA gltB → glutamate synthase, large subunit
RA 3,362,487 C→A 5.4% P117P (CCG→CCT yhcH ← DUF386 family protein, cupin superfamily
RA 3,364,026 G→T 8.5% H124N (CAT→AAT)  nanE ← putative N‑acetylmannosamine‑6‑P epimerase
RA 3,376,327 G→T 7.7% G257C (GGC→TGC)  degS → serine endoprotease, periplasmic
RA 3,392,695 G→T 6.4% R215S (CGT→AGT)  mreC ← cell wall structural complex MreBCD transmembrane component MreC
RA 3,415,190 G→T 10.6% G169G (GGG→GGT yhdY → putative amino‑acid transporter subunit
RA 3,416,890 T→G 17.6% noncoding (12/120 nt) rrfF ← 5S ribosomal RNA of rrnD operon
RA 3,416,899 A→G 9.3% noncoding (3/120 nt) rrfF ← 5S ribosomal RNA of rrnD operon
RA 3,427,211 C→A 7.4% H55N (CAT→AAT)  def → peptide deformylase
RA 3,435,321:1 +A 5.6% coding (137/390 nt) rpsK ← 30S ribosomal subunit protein S11
RA 3,435,321:2 +C 5.6% coding (137/390 nt) rpsK ← 30S ribosomal subunit protein S11
RA 3,435,321:3 +C 5.6% coding (137/390 nt) rpsK ← 30S ribosomal subunit protein S11
RA 3,435,322:1 +C 5.6% coding (136/390 nt) rpsK ← 30S ribosomal subunit protein S11
RA 3,435,322:2 +G 5.6% coding (136/390 nt) rpsK ← 30S ribosomal subunit protein S11
RA 3,435,322:3 +G 5.6% coding (136/390 nt) rpsK ← 30S ribosomal subunit protein S11
RA 3,435,323:1 +C 5.6% coding (135/390 nt) rpsK ← 30S ribosomal subunit protein S11
RA 3,435,323:2 +A 5.6% coding (135/390 nt) rpsK ← 30S ribosomal subunit protein S11
RA 3,435,323:3 +C 5.6% coding (135/390 nt) rpsK ← 30S ribosomal subunit protein S11
RA 3,435,323:4 +C 5.6% coding (135/390 nt) rpsK ← 30S ribosomal subunit protein S11
RA 3,435,326 C→G 7.0% W44C (TGG→TGC rpsK ← 30S ribosomal subunit protein S11
RA 3,478,876:1 +C 8.5% coding (302/405 nt) yhfA ← OsmC family protein
RA 3,478,876:2 +G 8.5% coding (302/405 nt) yhfA ← OsmC family protein
RA 3,478,876:3 +G 8.5% coding (302/405 nt) yhfA ← OsmC family protein
RA 3,478,876:4 +G 8.5% coding (302/405 nt) yhfA ← OsmC family protein
RA 3,495,185 C→T 7.0% L187F (CTC→TTC)  frlB → fructoselysine‑6‑P‑deglycase
RA 3,496,316 G→T 5.2% L206L (CTG→CTT frlC → fructoselysine 3‑epimerase
RA 3,505,455 C→A 5.9% V83V (GTG→GTT yhfZ ← putative DNA‑binding transcriptional regulator
RA 3,512,110 G→A 9.5% T105M (ACG→ATG)  aroK ← shikimate kinase I
RA 3,521,491 C→T 11.8% T555I (ACC→ATC)  yrfF → inner membrane protein
RA 3,534,225 C→A 12.5% R154S (CGC→AGC)  feoB → fused ferrous iron transporter, protein B: GTP‑binding protein/membrane protein
RA 3,590,908 C→A 11.8% A5S (GCG→TCG)  livK ← leucine transporter subunit
RA 3,611,549 C→A 7.0% V138V (GTC→GTA nikE → nickel transporter subunit
RA 3,616,061 T→C 5.2% Y1170Y (TAT→TAC rhsB → Rhs family putative polymorphic toxin, putative neighboring cell growth inhibitor
RA 3,617,301 A→C 15.4% pseudogene (55/351 nt) yrhC → pseudogene fragment
RA 3,617,887 T→C 7.3% F50F (TTT→TTC yhhI → putative transposase
RA 3,618,160 A→G 12.0% G141G (GGA→GGG yhhI → putative transposase
RA 3,632,623 G→T 8.7% intergenic (+122/+122) pitA → / ← uspB phosphate transporter, low‑affinity; tellurite importer/universal stress (ethanol tolerance) protein B
RA 3,638,069 A→G 7.1% R158R (CGT→CGC prlC ← oligopeptidase A
RA 3,655,351 C→A 5.1% T526T (ACC→ACA mdtF → anaerobic multidrug efflux transporter, ArcA‑regulated
RA 3,677,967 C→A 9.3% G338C (GGT→TGT)  yhjK ← cyclic‑di‑GMP phosphodiesterase
RA 3,705,495 G→T 8.2% intergenic (‑128/+101) yhjX ← / ← yhjY pyruvate‑inducible inner membrane protein, putative transporter/autotransporter beta‑domain protein
RA 3,723,046 C→T 5.6% M360I (ATG→ATA xylA ← D‑xylose isomerase
RA 3,742,456 C→A 11.8% P174T (CCT→ACT)  sgbH → 3‑keto‑L‑gulonate 6‑phosphate decarboxylase
RA 3,781,212 G→T 7.4% G339C (GGT→TGT)  envC → activator of AmiB,C murein hydrolases, septal ring factor
RA 3,806,482 C→T 5.7% A131V (GCC→GTC)  dfp → fused 4'‑phosphopantothenoylcysteine decarboxylase/phosphopantothenoylcysteine synthetase, FMN‑binding
RA 3,819,698 G→T 10.0% G377C (GGT→TGT)  recG → ATP‑dependent DNA helicase
RA 3,842,116 C→A 6.4% G461W (GGG→TGG)  uhpB ← sensory histidine kinase in two‑component regulatory sytem with UhpA
RA 3,843,111 G→T 8.0% P129H (CCC→CAC)  uhpB ← sensory histidine kinase in two‑component regulatory sytem with UhpA
RA 3,849,701 C→A 11.4% intergenic (‑34/‑74) yidH ← / → yidI DUF202 family inner membrane protein/inner membrane protein
RA 3,851,204 C→A 6.8% V187V (GTG→GTT yidJ ← sulfatase/phosphatase superfamily protein
RA 3,861,859 G→T 5.6% L271M (CTG→ATG)  yidR ← DUF3748 family protein
RA 3,896,548 C→A 6.4% E172* (GAA→TAA)  bglB ← cryptic phospho‑beta‑glucosidase B
RA 3,908,699 C→A 6.3% intergenic (‑139/+214) glmU ← / ← atpC fused N‑acetyl glucosamine‑1‑phosphate uridyltransferase/glucosamine‑1‑phosphate acetyl transferase/F1 sector of membrane‑bound ATP synthase, epsilon subunit
RA 3,911,251 G→T 7.8% F125L (TTC→TTA atpG ← F1 sector of membrane‑bound ATP synthase, gamma subunit
RA 3,923,931 G→T 13.8% L175M (CTG→ATG)  ravA ← hexameric AAA+ MoxR family ATPase, putative molecular chaperone
RA 3,933,454 G→T 12.3% P173P (CCC→CCA hsrA ← putative multidrug or homocysteine efflux system
RA 3,934,559 C→A 11.1% L43L (CTG→CTT yieP ← putative transcriptional regulator
RA 3,941,493 Δ1 bp 7.1% coding (48/339 nt) yifE → UPF0438 family protein
RA 3,947,728 C→A 9.5% T297T (ACC→ACA ilvD → dihydroxyacid dehydratase
RA 3,950,773 C→A 7.5% V136V (GTG→GTT ilvY ← transcriptional activator of ilvC; autorepressor
RA 3,970,297 T→A 5.4% F220L (TTT→TTA wzxE → O‑antigen translocase
RA 3,971,404 A→G 9.5% M174V (ATG→GTG)  wecF → TDP‑Fuc4NAc:lipidIIFuc4NAc transferase
RA 3,984,676 G→A 5.9% G55D (GGT→GAT)  cyaA → adenylate cyclase
RA 3,991,518 C→A 14.7% A59E (GCG→GAG)  uvrD → DNA‑dependent ATPase I and helicase II
RA 4,008,824 G→T 6.3% H236N (CAT→AAT)  ysgA ← putative carboxymethylenebutenolidase
RA 4,024,304 G→T 5.9% L10I (CTT→ATT)  fadB ← fused 3‑hydroxybutyryl‑CoA epimerase/delta(3)‑cis‑delta(2)‑trans‑enoyl‑CoA isomerase/enoyl‑CoA hydratase/3‑hydroxyacyl‑CoA dehydrogenase
RA 4,028,635 A→G 36.4% intergenic (+122/‑256) hemG → / → rrsA protoporphyrin oxidase, flavoprotein/16S ribosomal RNA of rrnA operon
RA 4,071,404 C→T 10.2% T199I (ACC→ATC)  yiiD → putative acetyltransferase
RA 4,078,537 G→T 6.9% H216N (CAC→AAC)  fdoG ← formate dehydrogenase‑O, large subunit
RA 4,089,933 C→A 12.3% G174V (GGG→GTG)  rhaT ← L‑rhamnose:proton symporter
RA 4,092,301 G→T 13.3% L228L (CTG→CTT kdgT → 2‑keto‑3‑deoxy‑D‑gluconate transporter
RA 4,116,114 C→T 5.9% A209T (GCA→ACA)  priA ← Primosome factor n' (replication factor Y)
RA 4,127,917 G→T 8.9% Y349* (TAC→TAA gldA ← glycerol dehydrogenase, NAD+ dependent; 1,2‑propanediol:NAD+ oxidoreductase
RA 4,135,627 C→A 10.4% R569S (CGC→AGC)  pflD → putative glycine radical domain‑containing pyruvate formate‑lyase
RA 4,163,914 A→G 10.3% Q302R (CAG→CGG)  birA → bifunctional biotin‑[acetylCoA carboxylase] holoenzyme synthetase/ DNA‑binding transcriptional repressor, bio‑5'‑AMP‑binding
RA 4,165,384 C→A 5.1% noncoding (69/76 nt) thrU → tRNA‑Thr
RA 4,165,449 C→T 20.2% noncoding (50/85 nt) tyrU → tRNA‑Tyr
RA 4,165,450 A→C 20.0% noncoding (51/85 nt) tyrU → tRNA‑Tyr
RA 4,173,034 C→T 17.7% S621F (TCC→TTC)  rpoB → RNA polymerase, beta subunit
RA 4,178,500 C→T 77.2% R1075C (CGT→TGT)  rpoC → RNA polymerase, beta prime subunit
RA 4,188,832 G→T 8.3% E39* (GAG→TAG)  nfi → endonuclease V; deoxyinosine 3' endonuclease
RA 4,191,263 C→A 10.7% P118P (CCG→CCT zraP ← Zn‑dependent periplasmic chaperone
RA 4,202,970 C→T 30.5% noncoding (3/120 nt) rrfE → 5S ribosomal RNA of rrnE operon
RA 4,217,090 G→T 9.5% W1112L (TGG→TTG)  metH → homocysteine‑N5‑methyltetrahydrofolate transmethylase, B12‑dependent
RA 4,224,570 C→A 6.5% S295S (TCC→TCA pgi → glucosephosphate isomerase
RA 4,238,850 C→T 13.0% Q318* (CAG→TAG)  lamB → maltose outer membrane porin (maltoporin)
RA 4,251,082 G→T 14.9% D186Y (GAT→TAT)  yjbM → uncharacterized protein
RA 4,261,710 G→T 5.5% P697Q (CCA→CAA)  uvrA ← ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC
RA 4,262,878 G→T 6.8% R308S (CGT→AGT)  uvrA ← ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC
RA 4,266,783 C→T 6.2% A462V (GCG→GTG)  yjcC → putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 4,283,069 G→T 6.3% G544* (GGA→TGA)  nrfE → heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfE
RA 4,286,214 T→C 7.3% intergenic (+492/+39) gltP → / ← yjcO glutamate/aspartate:proton symporter/Sel1 family TPR‑like repeat protein
RA 4,301,075 C→A 6.1% G262V (GGA→GTA)  alsB ← D‑allose transporter subunit
RA 4,301,118 C→A 8.5% G248C (GGT→TGT)  alsB ← D‑allose transporter subunit
RA 4,304,438 C→A 5.9% W161L (TGG→TTG)  phnP ← 5‑phospho‑alpha‑D‑ribosyl 1,2‑cyclic phosphate phosphodiesterase
RA 4,325,571 C→A 7.9% L426L (CTG→CTT adiC ← arginine:agmatine antiporter
RA 4,346,893 C→A 6.1% V514V (GTG→GTT cadA ← lysine decarboxylase, acid‑inducible
RA 4,355,525 G→A 5.6% P356S (CCG→TCG)  dcuA ← C4‑dicarboxylate antiporter
RA 4,364,724 G→A 6.8% L251L (CTG→TTG)  epmB ← EF‑P‑Lys34 lysylation protein; weak lysine 2,3‑aminomutase
RA 4,377,061 G→T 6.4% F709L (TTC→TTA mscM ← mechanosensitive channel protein, miniconductance
RA 4,381,069:1 +G 7.4% coding (258/1053 nt) rsgA ← ribosome small subunit‑dependent GTPase A
RA 4,443,450 G→T 7.4% L17F (TTG→TTT yjfF → inner membrane putative ABC superfamily sugar transporter permease
RA 4,450,791 C→A 8.7% V563L (GTG→TTG)  nrdD ← anaerobic ribonucleoside‑triphosphate reductase
RA 4,465,093 C→T 10.5% Q139* (CAG→TAG)  tabA → biofilm modulator regulated by toxins; DUF386 family protein, cupin superfamily
RA 4,508,484 C→T 15.9% A47A (GCC→GCT insA → IS1 repressor TnpA
RA 4,508,490 G→A 16.7% Q49Q (CAG→CAA insA → IS1 repressor TnpA
RA 4,508,826 G→A 5.9% pseudogene (289/504 nt) insB1 → IS1 transposase B;IS, phage, Tn; Transposon‑related functions; extrachromosomal; transposon related
RA 4,512,887 C→A 9.6% R342L (CGA→CTA)  yjhG ← putative dehydratase
RA 4,545,681 C→A 6.2% G153C (GGT→TGT)  yjiC ← uncharacterized protein
RA 4,548,219 C→A 5.1% M375I (ATG→ATT iadA ← isoaspartyl dipeptidase
RA 4,551,791 C→T 8.3% P234P (CCG→CCA yjiJ ← DUF1228 family putative inner membrane MFS superfamily transporter
RA 4,596,056 A→G 17.0% noncoding (48/87 nt) leuP ← tRNA‑Leu
RA 4,612,376:1 +A 6.2% coding (791/1332 nt) yjjJ → putative protein kinase
RA 4,612,376:2 +A 6.2% coding (791/1332 nt) yjjJ → putative protein kinase
RA 4,612,376:3 +T 6.2% coding (791/1332 nt) yjjJ → putative protein kinase
RA 4,612,376:4 +C 6.2% coding (791/1332 nt) yjjJ → putative protein kinase
RA 4,612,376:5 +A 6.2% coding (791/1332 nt) yjjJ → putative protein kinase
RA 4,612,379 T→C 6.4% L265P (CTT→CCT)  yjjJ → putative protein kinase

Unassigned missing coverage evidence
   seq id start end size ←reads reads→ gene description
* * ÷ CP009273 80526 80621 96 8 [7] [7] 9 leuL/leuO leu operon leader peptide/global transcription factor
* * ÷ CP009273 1524248 1524431 184 8 [7] [7] 9 ydcD uncharacterized protein
* * ÷ CP009273 2027294 2027423 130 8 [7] [7] 8 rseX/yedS sRNA antisense regulator of ompA and ompC translation, Hfq‑dependent/pseudogene, outer membrane protein homology; putative outer membrane protein
* * ÷ CP009273 2462825 2463051 227 10 [6] [5] 8 gtrS serotype‑specific glucosyl transferase, CPS‑53 (KpLE1) prophage
* * ÷ CP009273 2463644 2463764 121 9 [7] [4] 9 gtrS serotype‑specific glucosyl transferase, CPS‑53 (KpLE1) prophage
* * ÷ CP009273 3406892 3406987 96 11 [7] [6] 8 acrS/acrE acrAB operon transcriptional repressor/cytoplasmic membrane lipoprotein
* * ÷ CP009273 3448766 3448841 76 9 [7] [6] 9 gspA/gspC general secretory pathway component, cryptic/general secretory pathway component, cryptic
* * ÷ CP009273 3745309 3745418 110 8 [4] [4] 8 [yiaU] [yiaU]
* * ÷ CP009273 4249426 4249935 510 8 [5] [6] 8 [zur] [zur]

Unassigned new junction evidence
  seq id position reads (cov) reads (cov) score skew freq annotation gene product
* ? CP009273 360104 =40 (0.820)44 (0.900) 19/248 NT 52.4% intergenic (‑38/+557) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 360286 NA (NA)intergenic (‑220/+375) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
* ? CP009273 = 77690245 (0.920)5 (0.120) 4/208 NT 14.8% intergenic (+2/‑131) lysZ/lysQ tRNA‑Lys/tRNA‑Lys
?CP009273 777267 = 20 (0.490)intergenic (+159/‑274) lysQ/nadA tRNA‑Lys/quinolinate synthase, subunit A
* ? CP009273 1203246 =20 (0.410)17 (0.400) 9/216 NT 56.3% coding (290/630 nt) stfP e14 prophage; uncharacterized protein
?CP009273 1205075 = 9 (0.210)pseudogene (1/501 nt) stfE pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
* ? CP009273 = 120326119 (0.390)30 (0.700) 14/216 NT 70.1% coding (305/630 nt) stfP e14 prophage; uncharacterized protein
?CP009273 = 1205058 9 (0.210)pseudogene (18/501 nt) stfE pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
* ? CP009273 1972769 =32 (0.650)4 (0.080) 3/246 NT 11.2% intergenic (‑315/‑465) flhD/uspC flagellar class II regulon transcriptional activator, with FlhC/universal stress protein
?CP009273 3576788 = NA (NA)intergenic (+10/‑55) yrhA/insA pseudogene, interrupted by IS1E/IS1 repressor TnpA
* ? CP009273 = 2283592NA (NA)46 (0.950) 22/244 NT 88.5% noncoding (1/1195 nt) IS5 repeat region
?CP009273 2399636 = 6 (0.120)coding (485/939 nt) lrhA transcriptional repressor of flagellar, motility and chemotaxis genes
* ? CP009273 = 23996396 (0.120)57 (1.160) 26/248 NT 90.5% coding (482/939 nt) lrhA transcriptional repressor of flagellar, motility and chemotaxis genes
?CP009273 = 3124699 NA (NA)intergenic (+146/+1) insH1/yghQ IS5 transposase and trans‑activator/putative inner membrane polysaccharide flippase