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E. coli chemical tolerance: TOL hexanoic acid - Experiment Stats

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Notes

Publication:

Lennen RM, Jensen K, Mohammed ET, Malla S, Börner RA, Chekina K, et al. Adaptive laboratory evolution reveals general and specific chemical tolerance mechanisms and enhances biochemical production [Internet]. bioRxiv. 2019. p. 634105. doi:10.1101/634105

ALE, flask, and isolate counts

ALE replicate Flask count Isolate count
1 1 3
2 1 3
3 1 3
4 1 3
5 1 4
6 1 1
7 1 3
7 7 20

ALE experiment mutation counts

Mutation Type Unique Observed
Single Base Substitutions 21 61
Multiple Base Substitutions 0 0
Deletions 11 76
Insertions 5 50
Mobile Element Insertions 10 16
Amplifications 0 0
Gene Conversions 0 0
Inversions 0 0
Total 47 203

ALE experiment functional change counts

Functional Change Type Unique Observed
Intergenic 11 77
Noncoding 1 3
Pseudogene 0 0
Synonymous 0 0
Nonsynonymous 0 0
Total 12 80

Mutation Needle Plot

Mutation Targets

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