Epistasis: Epistasis2011 experiment stats

Notes

Publication:

Chou, Hsin-Hung, Hsuan-Chao Chiu, Nigel F. Delaney, Daniel Segrè, and Christopher J. Marx. 2011. “Diminishing Returns Epistasis among Beneficial Mutations Decelerates Adaptation.” Science 332 (6034): 1190–92.

ALE, flask, and isolate counts

ALE replicate	Flask count	Isolate count
1	1	1
1	1	1

ALE experiment mutation counts

Mutation Type	Unique	Observed
Single Base Substitutions	2	2
Multiple Base Substitutions	0	0
Deletions	4	4
Insertions	1	1
Mobile Element Insertions	0	0
Amplifications	0	0
Gene Conversions	0	0
Inversions	0	0
Total	7	7

ALE experiment functional change counts

Functional Change Type	Unique	Observed
Intergenic	5	5
Noncoding	0	0
Pseudogene	0	0
Synonymous	0	0
Nonsynonymous	0	0
Total	5	5

Mutation Needle Plot

Mutation Targets