| Predicted mutation | ||||||
|---|---|---|---|---|---|---|
| evidence | seq id | position | mutation | annotation | gene | description |
| RA | NC_000913 | 3,862,497 | C→T | pseudogene (1107/1617 nt) | glvC ← | pseudogene, arbutin specific enzyme IIC component of PTS,enzyme, Transport of small molecules: Carbohydrates, organic acids, alcohols, PTS system, arbutin‑like IIB component, PTS system, arbutin‑like IIC component |
| Read alignment evidence... | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| seq id | position | ref | new | freq | score (cons/poly) | reads | annotation | genes | product | ||
| * | NC_000913 | 3,862,497 | 0 | C | T | 100.0% | 245.1 / NA | 76 | pseudogene (1107/1617 nt) | glvC | pseudogene, arbutin specific enzyme IIC component of PTS,enzyme, Transport of small molecules: Carbohydrates, organic acids, alcohols, PTS system, arbutin‑like IIB component, PTS system, arbutin‑like IIC component |
| Reads supporting (aligned to +/- strand): ref base C (0/0); new base T (37/39); total (37/39) | |||||||||||
CACATGTTGAACTGCAGAATCAGTGTGCGGAAAACCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACCTAGTC‑AATCAGACCTCCGCCCATGTTGCCCACCACACCAAAGAGATACATTACGGTCGACATTGAGGCCGCCAGCACGGCGTGTACCGCAAACAGCAACGGTGAAATGAACAGGAAGGTAAATTCCAGCGGTT > NC_000913/3862363‑3862630 | cacaTGTTGAACTGCAGAATCAGTGTGCGGAAAACCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGt < 1:406332/139‑1 (MQ=255) tGTTGAACTGCAGAATCAGTGTGCGGAAAACCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGTGATCCAGTTTTGCGGTAAAACTTAGTC‑AAt < 1:1397583/139‑1 (MQ=255) aaCTGCAGAATCAGTGTGCGGAAAACCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGAc > 2:769412/1‑139 (MQ=255) cTGCAGAATCAGTGTGCGGAAAACCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCt < 1:769412/139‑1 (MQ=255) cAGAATCAGTGTGCGGAAAACCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCt < 1:337329/136‑1 (MQ=255) cAGAATCAGTGTGCGGAAAACCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCt > 2:337329/1‑136 (MQ=255) cAGAATCAGTGTGCGGAAAACCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCg > 1:375236/1‑139 (MQ=255) gAATCAGTGTGCGGAAAACCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCGcc < 2:510168/139‑1 (MQ=255) tgtgCGGAAAACCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTca > 1:1324331‑M1/1‑137 (MQ=255) aCCACGAAGTACAGCAGGGTAAAGCACGACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaa < 1:300345‑M1/139‑13 (MQ=255) aCCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaa > 2:960458‑M1/1‑127 (MQ=255) cagcagGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacacaaaagagatacatta < 2:562180‑M1/139‑24 (MQ=255) agGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggt < 1:60225‑M1/139‑28 (MQ=255) ggTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacatta < 2:365109‑M1/133‑24 (MQ=255) ggTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacatta > 1:365109‑M1/1‑110 (MQ=255) tAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgac > 2:728993‑M1/1‑108 (MQ=255) tAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgac > 2:1155715‑M1/1‑108 (MQ=255) tAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgac > 2:650806‑M1/1‑108 (MQ=255) aaGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCt > 1:1158715/1‑96 (MQ=255) aaGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCt < 2:1158715/96‑1 (MQ=255) aGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacatt > 2:1040407‑M1/1‑105 (MQ=255) acaACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTtaccacaccaaagagatacattacggtcgacattgag < 1:960458‑M1/139‑38 (MQ=255) aaCCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcacca < 1:962798‑M1/105‑6 (MQ=255) aaCCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcacca > 2:962798‑M1/1‑100 (MQ=255) aaTGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagataca < 2:1261991‑M1/115‑21 (MQ=255) aaTGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagataca > 1:1261991‑M1/1‑95 (MQ=255) tGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagc > 1:62528‑M1/1‑93 (MQ=255) tGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagaga < 2:844279‑M1/109‑17 (MQ=255) tGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagaga > 1:844279‑M1/1‑93 (MQ=255) ggCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagca < 2:62528‑M1/139‑48 (MQ=255) cGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacg < 1:1040407‑M1/139‑50 (MQ=255) cGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacac > 2:851458‑M1/1‑90 (MQ=255) cGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacac < 1:851458‑M1/98‑9 (MQ=255) aTTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTATTC‑AATCAGACCTCCG‑TCATGTTcagcacaccaaggagatacattacagtcgacattgaggccggcagcacggc < 2:802842‑M1/139‑52 (MQ=255) aTTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggc > 1:771509‑M1/1‑88 (MQ=255) aTTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagc < 1:509079‑M1/134‑47 (MQ=255) aTTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagc > 2:509079‑M1/1‑88 (MQ=255) tGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtg < 2:342931‑M1/139‑55 (MQ=255) ggTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgta < 2:771509‑M1/139‑57 (MQ=255) tCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacg > 2:1378103‑M1/1‑81 (MQ=255) tCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacg < 1:1378103‑M1/130‑50 (MQ=255) atatCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacag < 2:1150286‑M1/139‑67 (MQ=255) tatCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTc > 2:817820/1‑52 (MQ=255) tatCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTc < 1:817820/52‑1 (MQ=255) atCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagca < 1:728993‑M1/139‑69 (MQ=255) gTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaa > 2:438010‑M1/1‑62 (MQ=255) gTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaa > 2:914278‑M1/1‑62 (MQ=255) gCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCg < 1:1393100/52‑1 (MQ=255) gCTGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCg > 2:1393100/1‑52 (MQ=255) tGAACATCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaac < 2:375236‑M1/139‑83 (MQ=255) cATCTGGATCCAGTTTTGCGGTAAAACTTAGTCAAATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacgg < 2:968886‑M1/80‑27 (MQ=255) cATCGGGATCCAGTTTTGCGGTAAAACTTAGTCAAATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacgg > 1:968886‑M1/1‑54 (MQ=255) tCGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaacaggaag > 1:500218‑M1/1‑51 (MQ=255) cGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaacaggaagg > 2:1121206‑M1/1‑50 (MQ=255) cGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggc < 2:401791‑M1/101‑52 (MQ=255) cGGGATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggc > 1:401791‑M1/1‑50 (MQ=255) ggATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTT‑‑‑CACCACACCAAAGAGATa > 2:1406891/1‑66 (MQ=255) ggATCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTT‑‑‑CACCACACCAAAGAGATa < 1:1406891/66‑1 (MQ=255) tCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGttca < 1:595615/47‑3 (MQ=255) tCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGttca > 2:595615/1‑45 (MQ=255) tCCAGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaacaggaaggtaaat > 2:1267430‑M1/1‑45 (MQ=255) aGTTTTGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaacaggaaggtaaattcc < 1:1155715‑M1/139‑98 (MQ=255) ttttGCGGCAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTT‑‑‑CACCACACCaaa > 1:81121/1‑52 (MQ=255) ttttGCGGCAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTT‑‑‑CACCACACCaaa < 2:81121/52‑1 (MQ=255) tGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaacaggaaggtaaattccagcgg > 1:440127‑M1/1‑37 (MQ=255) tGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaacaggaaggtaaattccagcgg < 1:438010‑M1/139‑103 (MQ=255) tGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacacca < 1:933801/47‑5 (MQ=255) tGCGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacacca > 2:933801/1‑43 (MQ=255) cGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaacaggaaggtaaattccagcggtt > 1:780603‑M1/1‑35 (MQ=255) cGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaa > 1:53208‑M1/1‑35 (MQ=255) cGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaa < 2:53208‑M1/116‑82 (MQ=255) cGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaa < 2:254895‑M1/98‑64 (MQ=255) cGGTAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaa > 1:254895‑M1/1‑35 (MQ=255) tAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaacaggaaggtaaattccagcggttcgg < 2:1118766‑M1/139‑108 (MQ=255) tAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaacaggaaggtaaattccagcggttcgg < 1:1267430‑M1/139‑108 (MQ=255) tAAAACTTAGTC‑AATCAGACCTCCG‑CCATGTTcaccacaccaaagagatacattacggtcgacattgaggccgccagcacggcgtgtaccgcaaacagcaacggtgaaatgaacaggaaggtaaattccagcggttcgg > 1:1118766‑M1/1‑32 (MQ=255) | CACATGTTGAACTGCAGAATCAGTGTGCGGAAAACCACGAAGTACAGCAGGGTAAAGCACAACCCAATGGCGATTTGGGTCAGCATCATATCCGCGTGGTTGCTGAACATCGGGATCCAGTTTTGCGGTAAAACCTAGTC‑AATCAGACCTCCGCCCATGTTGCCCACCACACCAAAGAGATACATTACGGTCGACATTGAGGCCGCCAGCACGGCGTGTACCGCAAACAGCAACGGTGAAATGAACAGGAAGGTAAATTCCAGCGGTT > NC_000913/3862363‑3862630 |
| Alignment Legend |
|---|
Aligned base mismatch/match (shaded by quality score): ATCG/ATCG < 3 ≤ ATCG/ATCG < 27 ≤ ATCG/ATCG < 36 ≤ ATCG/ATCG < 39 ≤ ATCG/ATCG < 40 ≤ ATCG/ATCG |
Unaligned base: atcg Masked matching base: atcg Alignment gap: ‑ Deleted base: ‑ |