Predicted mutation
evidence seq id position mutation annotation gene description
RA NC_000913 675,570 C→T *326* (TAG→TAA ybeQ ← Sel1 family TPR‑like repeat protein

Read alignment evidence...
  seq id position ref new freq score (cons/poly) reads annotation genes product
*NC_000913675,5700CT100.0% 215.1 / NA 68*326* (TAG→TAAybeQSel1 family TPR‑like repeat protein
Reads supporting (aligned to +/- strand):  ref base C (0/0);  new base T (32/36);  total (32/36)

GAAGTGCTGACGCTATGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTCTACAGTAAATCTTCAGTCTCACGAATTTCCTGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTCTTCCTTCTCCGTAGTGATACATAATGGC  >  NC_000913/675435‑675701
                                                                                                                                       |                                                                                                                                   
gAAGTGCTGACGCTATGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTAc                                                                                                                                  >  2:237869/1‑139 (MQ=255)
gAAGTGCTGACGCTATGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTAc                                                                                                                                  <  1:237869/139‑1 (MQ=255)
   gTGCTGACGCTATGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGt                                                                                                                               <  2:31404/139‑1 (MQ=255)
    tGCTGACGCTATGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTa                                                                                                                              <  1:106057/139‑1 (MQ=255)
      cTGACGCTATGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTAc                                                                                                                                  >  2:317551/1‑133 (MQ=255)
      cTGACGCTATGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTAc                                                                                                                                  <  1:317551/133‑1 (MQ=255)
      cTGACGCTATGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTaaa                                                                                                                            >  1:155466/1‑139 (MQ=255)
          cGCTATGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCtt                                                                                                                        <  2:155466/139‑1 (MQ=255)
              aTGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGt                                                                                                                    >  1:265139/1‑139 (MQ=255)
              aTGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTAGTTTTTATCTTTACAGTAAATCtt                                                                                                                        <  2:978777/135‑1 (MQ=255)
              aTGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTAGTTTTTATCTTTACAGTAAATCtt                                                                                                                        >  1:978777/1‑135 (MQ=255)
                   cGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCAc                                                                                                               <  1:742984/139‑1 (MQ=255)
                   cGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCAc                                                                                                               >  2:149653/1‑139 (MQ=255)
                   cGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGAAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCAc                                                                                                               <  1:37822/139‑1 (MQ=255)
                       aTGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAAt                                                                                                           >  2:746073/1‑139 (MQ=255)
                                                 gCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTa                                                                                                                              >  2:978481/1‑94 (MQ=255)
                                                 gCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTa                                                                                                                              <  1:978481/94‑1 (MQ=255)
                                                 gCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGa                                                                                >  1:601630/1‑139 (MQ=255)
                                                      tttGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACt                                                                           <  1:356076/139‑1 (MQ=255)
                                                         gAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGaa                                                                        <  2:1149451/139‑1 (MQ=255)
                                                               tAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTAc                                                                  >  2:183041/1‑139 (MQ=255)
                                                                     tCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACAtct                                                                                           <  2:979758/108‑1 (MQ=255)
                                                                     tCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACAtct                                                                                           >  1:979758/1‑108 (MQ=255)
                                                                             cGCACAGCAATAAAGGGAATATGGGCCGAATGAAATTCCCCGGGCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGGCATCGCTGGTTCCGGATAATTGAACTGTACTATACAGGACgaaa                                                    >  2:1260166/1‑137 (MQ=255)
                                                                              gCACAGCAATAA‑‑AGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGcc                                                 >  1:905019/1‑139 (MQ=255)
                                                                               cacaGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCAc                                                                                                               >  1:153852/1‑79 (MQ=255)
                                                                               cacaGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCAc                                                                                                               <  2:153852/79‑1 (MQ=255)
                                                                               cacaGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGc                                                  >  2:438281/1‑139 (MQ=255)
                                                                               cacaGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGc                                                  <  2:601630/139‑1 (MQ=255)
                                                                                  aGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCAc                                                                                                               <  1:1268095/76‑1 (MQ=255)
                                                                                  aGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCAc                                                                                                               >  2:1268095/1‑76 (MQ=255)
                                                                                   gCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGt                                              >  1:738073/1‑139 (MQ=255)
                                                                                           gagaATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATc                                      <  2:265139/139‑1 (MQ=255)
                                                                                            agaATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGaa                                                                        <  2:591471/104‑1 (MQ=255)
                                                                                            agaATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGaa                                                                        >  1:591471/1‑104 (MQ=255)
                                                                                             gaATATGCGCCGAATGACATTCCCCGGTCCTTGGTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTGTACGATACAGGTCGAGAGCCTGTCGGAGATCGa                                    <  1:1260166/139‑1 (MQ=255)
                                                                                              aaTATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCtt                                                                                                                        >  1:173483/1‑55 (MQ=255)
                                                                                              aaTATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCtt                                                                                                                        <  2:173483/55‑1 (MQ=255)
                                                                                              aaTATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGAc                                   >  2:1162122/1‑139 (MQ=255)
                                                                                              aaTATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGAc                                   >  1:91179/1‑139 (MQ=255)
                                                                                               atatGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACa                                  <  2:1185331/139‑1 (MQ=255)
                                                                                               atatGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACa                                  <  1:438281/139‑1 (MQ=255)
                                                                                                 atGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAgg                                >  2:237648/1‑139 (MQ=255)
                                                                                                  tGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGt                               <  2:950382/139‑1 (MQ=255)
                                                                                                  tGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGt                               <  2:905019/139‑1 (MQ=255)
                                                                                                   gggCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACg                                                                                                              >  2:121770/1‑60 (MQ=255)
                                                                                                   gggCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACg                                                                                                              <  1:121770/60‑1 (MQ=255)
                                                                                                   gggCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGaa                                                                        >  2:1008924/1‑97 (MQ=255)
                                                                                                   gggCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGaa                                                                        <  1:1008924/97‑1 (MQ=255)
                                                                                                   gggCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTc                              >  1:1019049/1‑139 (MQ=255)
                                                                                                   gggCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTc                              >  1:952441/1‑139 (MQ=255)
                                                                                                      ccGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGt                                              <  1:4236/120‑1 (MQ=255)
                                                                                                      ccGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGt                                              >  2:4236/1‑120 (MQ=255)
                                                                                                      ccGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTcttc                           >  2:875327/1‑139 (MQ=255)
                                                                                                      ccGAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTcttc                           <  1:183041/139‑1 (MQ=255)
                                                                                                        gAATGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGTCAGGTcttcct                         >  1:704335/1‑139 (MQ=255)
                                                                                                          aTGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACAtct                                                                                           >  2:1011681/1‑71 (MQ=255)
                                                                                                          aTGAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACAtct                                                                                           <  1:1011681/71‑1 (MQ=255)
                                                                                                            gAAATTCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTCTTCCTtctc                     <  2:952441/139‑1 (MQ=255)
                                                                                                              atttCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTCTTCCTTCTCCg                   <  2:738073/137‑1 (MQ=255)
                                                                                                                ttCCCCGGCCCTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTCTTCCTTCTCCGTa                 <  2:1019049/139‑1 (MQ=255)
                                                                                                                        cccTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTcttc                           <  2:638288/121‑1 (MQ=255)
                                                                                                                        cccTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTcttc                           >  1:638288/1‑121 (MQ=255)
                                                                                                                          cTTGTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTCTTCCTTCTCCGTAGTGATACATa       <  1:317254/139‑1 (MQ=255)
                                                                                                                             gTTTTTATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACAGCTCTGGCTCCGGATGACTGAACTTTACGATACAGGGCGAGAGCCTGTCGGAGATCGACAGGGCTTCCTTCTCCGTAGTGATACATAATg    >  2:589942/1‑139 (MQ=255)
                                                                                                                               ttttATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTCTTCCTTCTCCGTAGTGATACATAATGGc  <  2:426361/139‑1 (MQ=255)
                                                                                                                               ttttATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTCTTCCTTCTCCGTAGTGATACATAATGGc  <  1:746073/139‑1 (MQ=255)
                                                                                                                               ttttATCTTTACAGTAAATCTTCAGTCTCACGAATTTCCGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTCTTCCTTCTCCGTAGTGATACATAATGGc  <  1:1162122/139‑1 (MQ=255)
                                                                                                                                       |                                                                                                                                   
GAAGTGCTGACGCTATGCCCGAAATGTGGTCATGACCAGTTCCAGAGACGCCCGTTTGAGCCGTAATAGTCTGATTTCGCACAGCAATAAAGAGAATATGGGCCGAATGAAATTCCCCGGCCCTTGTTTTTATCTCTACAGTAAATCTTCAGTCTCACGAATTTCCTGACTGACATCTCTGGTTCCGGATGACTGAACTTTACGATACAGGTCGAGAGCCTGTCGGAGATCGACAGGTCTTCCTTCTCCGTAGTGATACATAATGGC  >  NC_000913/675435‑675701

Alignment Legend
Aligned base mismatch/match (shaded by quality score): ATCG/ATCG < 3 ≤ ATCG/ATCG < 16 ≤ ATCG/ATCG < 34 ≤ ATCG/ATCG < 39 ≤ ATCG/ATCG < 40 ≤ ATCG/ATCG
Unaligned base: atcg    Masked matching base: atcg    Alignment gap:     Deleted base: