| Predicted mutation | |||||||
|---|---|---|---|---|---|---|---|
| evidence | seq id | position | mutation | freq | annotation | gene | description |
| RA | NC_000913 | 1,466,711 | T→C | 17.7% | pseudogene (1320/2513 nt) | ydbA → | pseudogene, autotransporter homolog, interrupted by IS2 and IS30 |
| Read alignment evidence... | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| seq id | position | ref | new | freq | score (cons/poly) | reads | annotation | genes | product | ||
| * | NC_000913 | 1,466,711 | 0 | T | C | 17.7% | 72.8 / 5.4 | 35 | pseudogene (1320/2513 nt) | ydbA | pseudogene, autotransporter homolog, interrupted by IS2 and IS30 |
| Reads supporting (aligned to +/- strand): ref base T (19/9); new base C (4/2); total (23/12) | |||||||||||
| Fisher's exact test for biased strand distribution p-value = 1.00e+00 | |||||||||||
| Kolmogorov-Smirnov test that lower quality scores support variant p-value = 8.17e-01 | |||||||||||
GCGGCGGTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGCGGCACCGGCACTCAGATCAACGGTAACGACGCCACCGCGAATAACAGTGGAAAAAC > NC_000913/1466467‑1466968 | gcggcggTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATACAGGTTGACGGAGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TACACCGGTACGGAAATTGCCGGCAAAAACGGGAAGGTTATTCAGGAACGCGACCTGGaggc > 2:312983/1‑286 (MQ=17) cACGATATTGATATCACCGGCGACAGCGCAACTGTGGATAACAAGGGCACCATGCCCGTCACCGCTCCGGAGTCCATCGGTATCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGTGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCTTTGCCGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAgcggcg < 1:312983/289‑1 (MQ=255) tttGAGATCACCGGCGAAAGCGAAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTAGCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGAACCGGCACGCAGATTAACGGGGATGACGCCACGGAAAACAACAAGGGCAAAAGCAGCGTCGGAGGTAAGGAA‑GACACCGGTACGGAAATTACTGGCAATAACGGAAAAGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑Gt < 2:73482/287‑1 (MQ=17) gCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAg < 2:409884/265‑1 (MQ=255) gCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCAATCGGTATCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAg > 1:409884/1‑265 (MQ=255) cGGTGGAGAACAAGGGCACCAGGACCGTAACCGATCCGGAGTCCATCGGTATCAAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCa < 2:138542/265‑1 (MQ=255) cAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGat > 1:138542/1‑265 (MQ=255) gggCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCTATCACCAATGGTGGCACCGGCACGCAGATTAACGGTTACGACGCCACGGCGAACAACAACGGAAAAACCACCGTTGACGGAAAGGAT‑TACACCGGTACGGAAATCGCGGGCACTAACGGGAATGTGATTCTGGATGGCGACCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATAACATCGGCGACAGCGCAACGGTTGac > 2:228555/1‑288 (MQ=17) tCACCGATCCGGAGTCCATCGGTATCCAGGTTGACGGCGACCAGGCGGTTGTCAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGACGACGCCACCGCAAATAACAGCGGCAAAACCACCGTTGACGGCAAAGAT‑TCCACGGGTACCGAAATTGCTGGCAATAACGGGAAGGTAAATCAGGACGCCTATATACATGTAAGC‑GTGGCGAGGCACGGTATTGTTAAACCCGGCGAGAGCGCCGTGGTGTATAACAAaggaatcaa > 2:336426/1‑283 (MQ=255) gAGTCCATCGGTATCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCAGCCTGACCGTCAcc > 1:364916/1‑288 (MQ=255) cATCGGTATCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGACGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCCACGGTGGATAAAAAGGGCACCATGACCGTCACAGATCCg > 1:132227/1‑289 (MQ=255) aTCGGTATCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTAATTCAGGACGGGGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAAAGGTGGATAACCACGGAACGATGACCGTCACCGATCCgg > 2:411166/1‑289 (MQ=255) tCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATCGCTGGCAATAACGGGAAGGTGATTCAGGACGGAGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACCGCGCAACGGTGGCTAACAAGGACATCATGACCGTCACAGAACCGGAGTcc > 1:219691/1‑287 (MQ=255) gACGGCTACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCa < 2:393450/206‑1 (MQ=255) gACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGCTCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATGACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTAccc > 1:213560/1‑289 (MQ=255) gACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGACGACGCCACGGCAAATAACAGCGGCAAAACCACTGTTGACGGAAAGGAT‑TCCACCGGTACCGAAATCGCTGGCAATAACGGGAAGGTGAATGTGGACGGCGACCTGAATGTTACCGGCGGTG‑AGCATGGTATTGAGAGCATTGGTGACAGCGGAACGGTGGACAACAAAGGAACTATGGCTGTTACCGATCCGCAgcctattggcttgc > 2:202533/1‑276 (MQ=255) gACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCAACGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCa > 1:393450/1‑206 (MQ=255) cGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGt > 1:357452/1‑208 (MQ=255) cGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGt < 2:357452/208‑1 (MQ=255) cGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGAAAATTGCGGGCAATAACGGGAGGGTGATTCAGGACGGCGACCTGGATGTCAGCGGCGGCG‑CGCACGGTATTGAGAACACCGGCGACAGCGCCACGGTGGATAACAAGGGCACCATTACCTGCACCGATCCGGAGTCCATTGGGATcccg > 2:129363/1‑287 (MQ=17) cGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAg < 2:271351/223‑1 (MQ=255) cGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAg > 1:271351/1‑223 (MQ=255) cgcCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTAAATAACGAAGGc > 2:356491/1‑289 (MQ=255) aCGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGCTTGACGGCGACGAGGCCATCCTCAATACACAAGGCGCGCGCACTa > 1:387768/1‑288 (MQ=255) atgaCGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGCGGCACCGGCACTCAGCTCa > 1:322768/1‑288 (MQ=255) atgaCGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGCGGCACCGGCACTCAGATCa > 2:27951/1‑288 (MQ=255) atgaCGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGAGTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGCGGCACCGGCACTCAGATCa > 1:91957/1‑288 (MQ=255) agacaacGGAAAAACCACCGTGTACGGC‑AGTATGTCCACCGGTACGGAAATTGCGTGCAATAACGGGAAGGTGAGTCAGGACGGCGATCTGCATTTCTGCGGCGTCG‑GTCGCGGTATTGCGAGCACCGGCAAAAGCGCAACGGCGGCAACCTAGGGTACCTTTAAGGTCACCGATCCGGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTCGATAACGAAGGCGAGAGCACTATCACCAATGGCGGCACCGGCACTCAGATCAACGGTAACGACGCCAcc < 2:132227/287‑1 (MQ=255) gaagtataaggtcaaggTTGACGGGAAAGAT‑TCCACCGGTACGGAAATCACCGGTCATAAGGTGAAAGTGATTCAGGACGGTGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTAATATCACCGGTGACAGCGCAACGGTGGGTAACAAGGGCACCATGACCGTCACCGATCCTGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGCGGCACCGGCACTCAGATCAACGGTAACGACGCCa < 2:111872/268‑1 (MQ=11) cGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGCTTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGCGGCACCGGCACCCAGATCAACGGTAACGACGCCCCCGCGAATAAAAGTGGaaaa > 2:61322/1‑289 (MQ=255) tatccgCAAGGAT‑TCAACCGGTACGGAAATAAACGGTAATAACGGAAAAGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTGACGGTATTGATATCACCGGGGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGCGGCACCGGCACTCAGATCAACGGTAACGACGCCACCGCGAATAACAGTGGAAAAAc < 2:159854/283‑1 (MQ=14) ggAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGTTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGCGGCACCGGCACTCAGATCAACGGTAACGACGCCa < 1:298417/257‑1 (MQ=255) ggAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGCGGCACCGGCACTCAGATCAACGGTAACGACGCCa > 2:298417/1‑257 (MQ=255) t‑tCCACCGGTACGGAAATCAACGGTAATAACGGAAAAGTTATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGcggcac < 2:165953/225‑1 (MQ=11) t‑tCCACCGGTACGGAAATCAACGGTAATAACGGAAAAGTTATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGcggcac > 1:165953/1‑225 (MQ=11) | GCGGCGGTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGGTTGACGGCGACCAGGCGGTTGTTAACAACGAAGGCGAGAGCGCCATCACCAACGGTGGCACCGGCACGCAGATTAACGGTGATGACGCCACGGCAAACAACAACGGCAAAACCACCGTTGACGGCAAGGAT‑TCCACCGGTACGGAAATTGCTGGCAATAACGGGAAGGTGATTCAGGACGGCGATCTGGATGTCAGCGGCGGCG‑GTCACGGTATTGATATCACCGGCGACAGCGCAACGGTGGATAACAAGGGCACCATGACCGTCACCGATCCGGAGTCCATCGGTATCCAGATTGACGGCGACCAGGCCATCGTCAATAACGAAGGCGAGAGCACTATCACCAATGGCGGCACCGGCACTCAGATCAACGGTAACGACGCCACCGCGAATAACAGTGGAAAAAC > NC_000913/1466467‑1466968 |
| Alignment Legend |
|---|
Aligned base mismatch/match (shaded by quality score): ATCG/ATCG < 3 ≤ ATCG/ATCG < 9 ≤ ATCG/ATCG < 13 ≤ ATCG/ATCG < 31 ≤ ATCG/ATCG < 38 ≤ ATCG/ATCG |
Unaligned base: atcg Masked matching base: atcg Alignment gap: ‑ Deleted base: ‑ |