| Predicted mutation | |||||||
|---|---|---|---|---|---|---|---|
| evidence | seq id | position | mutation | freq | annotation | gene | description |
| RA | NC_000913 | 1,708,901 | A→C | 28.5% | R661R (CGA→CGC) | rsxC → | SoxR [2Fe‑2S] reducing system protein RsxC |
| Read alignment evidence... | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| seq id | position | ref | new | freq | score (cons/poly) | reads | annotation | genes | product | ||
| * | NC_000913 | 1,708,901 | 0 | A | C | 28.5% | 68.4 / 19.0 | 63 | R661R (CGA→CGC) | rsxC | SoxR [2Fe‑2S] reducing system protein RsxC |
| Reads supporting (aligned to +/- strand): ref base A (28/17); new base C (16/2); total (44/19) | |||||||||||
| Fisher's exact test for biased strand distribution p-value = 6.59e-02 | |||||||||||
| Kolmogorov-Smirnov test that lower quality scores support variant p-value = 1.00e+00 | |||||||||||
GGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGTGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCGGTACCAGAAGA > NC_000913/1708763‑1709047 | ggTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGTGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCGGAGGCTCGGCAGCACGGAGGTCCGCGCAAAGCGGCCGGGGAAGGCGCGATTGCCCGCGGCACAgcgca > 1:153759/1‑149 (MQ=2) cgcgCAAACCCGCCCTCGAAGCCGCTATTGCCCGTGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCCGAGCCATAACAACATTTCGATCCGCTCAAATCCGGCGTCGAATCCGCTATTGCCCGAGCCAAAGCGCGCAAACggg < 2:1228620/150‑1 (MQ=17) aaaCCCGCCGTCGAAGCAGCTATTGCCCGGGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCCGACCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAg < 1:1760614/150‑1 (MQ=255) gccgccGTCGAAGCCGCTATTGCCCGTGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCGGAGCCAGAAGAACAGGTAGATCCGCGCAAAGCCGCAGTAGCAGCGGCTATTGCCCGAGCGAAGGCCAGCAACCGGGAACAGCag > 2:1525804/1‑149 (MQ=11) cGAAGCCGCTATTGCCCGTGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTAGATCCGCGCAAAGCCGCCGTAGAAGCCGCTATTGCCCGAGCCCACGCCCGCAAACGGGACCAGCACCCGGCTaa > 2:919432/1‑150 (MQ=17) ccGCTATTGCCCGTGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGCGCCAAAGCGCGCAAACGGGACCAGCACCCGGCTAATGCgg > 1:328675/1‑150 (MQ=255) tATTGCCCGTGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCGAACGGGAGCAGCCACCGGCTAATGCGGGGcc > 1:68091/1‑150 (MQ=255) gCCCGTGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCAGCCGTATACGCCGCTATTGCCACAGCCAAACCGCGCACACCGGACCAGAAACCCGCTAATGCCGAGACagaa > 1:1120080/1‑150 (MQ=14) tGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTAGATCCGCGCAAAGCGGCCGTAGACGCGGCTATTGCCCGCGCGAAAGCCCGCAAACCCGCCCAGCAGCAGGATAATGCGGAGCCAGAAGAGCa > 2:367006/1‑150 (MQ=14) gCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCGGCCGTAGCCGCCGCTATTGCCCGCGCAAAAGCGCGCAAACGGGAACAGCACCAGGATAATGCGGAGCAAGAAGACCAg > 2:1790340/1‑150 (MQ=14) cAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTAGCCGCCGCTATTGCCCGCGCCAAAGCCAGCAAACGCGAACAGCAACAGGCTGATACGGAGCCAGAAGAACACGt > 1:1589260/1‑150 (MQ=14) tcgaaaGCTTTAACAGCAACAGGCTAATGCGGATCAAGAACTACATGTCGATCCGCGCAAAGCCGCCGTCGAAGCAGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATcc < 1:1927985/146‑1 (MQ=14) tcGCAAGCTTTAACAGCAACAGTCTAATGCGTATCAAGAACAACATGTCGATCCGCGCAAAGCCGCCGTCGAAGCAGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATcc < 1:1937414/149‑1 (MQ=14) cTGGAACAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCGGCCGTCGAAGCCGCTATTGCCCGCGCCAAAGCGAGCAAACCCGAACAGCACCAGGGTGAAGCCGAGCCAGAAGAACAGGTGGATACGCGaaaa > 1:2239114/1‑150 (MQ=11) aCAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTAGAAGCCGCTATTGCCCGCGCCAAAGCCCGCAAACGGGACCAGCAACCGGCTAAAGCGGAGCCAGAAGAACACGTAGATACGCACAAagcagc > 1:1668055/1‑150 (MQ=14) cAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTAGAAGCCGCTATTGCCCGCGCCAAAGCCCGCAAACGCGAACAGCACCCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGca > 2:1942519/1‑149 (MQ=17) gCAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTAGAAGCGGCTATTGCCCGCGCGAAAGCCAGCAAACGGGAACAGCAACAGGCTAATGAGGAGCCAGAAGAACAGGTTGATCAGCGCAAAGCGGCAGt > 2:1890714/1‑150 (MQ=14) cAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCCAGCAAACGGGAACAGCAACAGGCTAATGAGGAGCCAGAAGAACAGGTTCGTACGCGCAACGCGGCAGtt > 2:1587928/1‑149 (MQ=14) aCAGGCTAATGCGGAACCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGa > 2:1873305/1‑90 (MQ=255) aCAGGCTAATGCGGAACCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGa < 1:1873305/90‑1 (MQ=255) cAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCAGCCGTCGAAGCCGCTATTCCCAGAGCCAAAGAGAGCAAACGGGAACAGAAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATAAGCGCAAAGCTGCCGTCGac > 2:593129/1‑149 (MQ=17) aGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGCGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCGGCAGtagcac > 1:1981059/1‑145 (MQ=255) ggCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCAGTAGAAGCGGCTATTGCCCGCGCAAAAGCCCGCAAACGCGAACAGCAACAGGCTAATGCGGAGCAATAAGAACAGTTAGATCCGCGCAAAGCAGCAGttgccgc > 2:2288682/1‑144 (MQ=11) cTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCGGCCGTAGAAGCCGCTATTGCCCGCGCAAAAGCCAAAAAACACGAACAGCAACACGCTAAAGCGGAGACAGAAGAACAAGTTGATACACGAAAAGCTGACGTTGCAGccg > 2:1696469/1‑148 (MQ=9) cactGCCGAGCCAGAACAACAGGTCGATCCGCGCAACGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGc < 1:593129/147‑1 (MQ=255) tGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGCAGCGGCTAt > 1:1697181/1‑150 (MQ=255) gCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGACGCCGCTATTGCCCGCGCCAAAGCCCGCAAACGGGAACAGCAACAGGCTAATGCGGAGCCAGAAGACCAGGTGGATCCGCGCAAAGCGGCCGGCGCCGCGGCTagt > 1:299918/1‑148 (MQ=14) gCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGCGCCAAAGCGCGCAACCGGGAACAGCAACCGGCTAATGCGGGGCCAGAAGAACAGGTTGATCCGCGCATAGCGGCCGTGGCAGCGGCTAtt > 1:2373825/1‑150 (MQ=14) gCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGCGCCAAAGCCCGCAAACGGGAACAGCACCCGGGTAATGCGGAGCCAGAAGAACCGGTTGATCCGCGCAAAGCGGCAGTGGAAGCGGCTAtt > 1:1989277/1‑150 (MQ=17) ccGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTAGATACGAGCAAAGCTGCCGTCTAAACGGCTATTg > 2:1767809/1‑150 (MQ=17) ggaaccAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCagaag > 1:1352380/5‑107 (MQ=255) ggaaccAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCagaag < 2:1352380/103‑1 (MQ=255) gAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGCGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACACGTTGATCCGCGCAAAGCTGCAGTAGCCGCGGCTAttccc > 1:1664811/1‑147 (MQ=17) gCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCAcg > 1:23000/1‑150 (MQ=255) aGAACAACACGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCCGCTAATGCCGAGCCAGAAGAACAGGTAGATCCGCGCAAAGCTGACGTCGACGCGCCTATTGCACgcgc > 1:638107/1‑150 (MQ=17) aacaacAGGTCTATCCTCGCAAAGCCGCCGTCGAATCCGATATTTCCCGAGCCAAAGCGCGCAAACGTTAACTTCAACCTGCTAATGTGGATCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCa < 2:1205165/150‑1 (MQ=21) aacaGCTCGATCCGGGCCATGCCTCGGTCGAAGCCGCTATCTCCCGAGCCAAAGCGCGCAATCGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAg < 1:922303/150‑1 (MQ=21) acaGGTCTATCCGCCCAACCCCCCCGCAGAAGCCCCTACTGCGCGAGCCCATTCACGCCTGCGGTCACCCGAACCGGCTAATGCGGACCCAGAAGAACAGGTCGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGc < 1:287666/150‑1 (MQ=9) acaGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCagaaga < 1:185231/96‑1 (MQ=255) acaGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCagaaga > 2:185231/1‑96 (MQ=255) acaGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCAGTAGAAGCGGCTATTGCACGCGCCAAAGc > 2:35442/1‑150 (MQ=255) acaGGTCGATCCCCGCACAGCCTCCTGCGACCCCGCTATTGCCCGCGCCCAAGCGCGCAACCGGGAACAGCAACAGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGc < 1:2282650/150‑1 (MQ=14) aGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAg < 2:1003247/86‑1 (MQ=255) aGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAg > 1:1003247/1‑86 (MQ=255) ggTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGa > 2:734185/1‑63 (MQ=255) ggTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGa < 1:734185/63‑1 (MQ=255) ggTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGACCAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCAGCGCAAAGCTGCCGTAGCAGCGGCTATTGCACGCGCCAAAGccag > 1:983407/1‑147 (MQ=17) cgTCGATCCGCGCAAAGCCGCCGTCTAAGACGCTATTGCCCGAGCCAAAGCTCGCAATCTGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGCACg < 2:68091/149‑1 (MQ=14) aTCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGATGCCCTGTCAGCGGCTATTCCACGGGGCGAAGCACGCaacc > 1:244322/1‑148 (MQ=17) gcAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTAGCCGCGGCTATTGCCCGCGCCCACGCCCGCAAggaggacc > 1:2456770/1‑143 (MQ=17) gccgccGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGCACGCAAGCTGGAACAGCaa > 2:350939/1‑150 (MQ=255) tCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCg > 1:590301/1‑96 (MQ=255) tCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCg < 2:590301/96‑1 (MQ=255) aGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGCAGCGGCTATTGCACGCGCCAACGCCCGCAAGCTGGCAGAGCAACAGGCTACTGc > 1:2477703/1‑150 (MQ=25) aGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGCAAGCAAGCAGGAACAGCAACAGGCTAATGc > 1:1401561/1‑150 (MQ=255) aGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTAGAAGCGGCTATTGCCCGCGCAAAAGCCCAAAAACACGAACAGCAAAAGGATaaaaa > 2:1053626/1‑147 (MQ=18) ccGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGCACGCAAGCTCGAACAGCAACAGGCTAATGCgg > 1:557230/1‑150 (MQ=255) cGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCGGt > 2:926815/1‑150 (MQ=255) ttGCCCGATCCAAAGCGCGCAAACTGTAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCGGTACCag < 1:1767809/150‑1 (MQ=255) gCCCGCGCCAAAGCGCGCAATCTGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATc < 1:2177913/67‑1 (MQ=14) gCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGCACGCa > 1:1827850/1‑115 (MQ=255) gCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGCACGCa < 2:1827850/115‑1 (MQ=255) ccGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCAGTAGAAGCGGCTATTGAACGCAACAAAGAACTCAAGCTGGAACAGCAAAAGGCTAATGCGGAACCagaaga > 2:1789992/1‑150 (MQ=17) | GGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGTGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCCGAGCCAGAACAACAGGTCGATCCGCGCAAAGCCGCCGTCGAAGCCGCTATTGCCCGAGCCAAAGCGCGCAAACGGGAACAGCAACCGGCTAATGCGGAGCCAGAAGAACAGGTTGATCCGCGCAAAGCTGCCGTCGAAGCGGCTATTGCACGCGCCAAAGCACGCAAGCTGGAACAGCAACAGGCTAATGCGGTACCAGAAGA > NC_000913/1708763‑1709047 |
| Alignment Legend |
|---|
Aligned base mismatch/match (shaded by quality score): ATCG/ATCG < 3 ≤ ATCG/ATCG < 14 ≤ ATCG/ATCG < 15 ≤ ATCG/ATCG < 32 ≤ ATCG/ATCG < 36 ≤ ATCG/ATCG |
Unaligned base: atcg Masked matching base: atcg Alignment gap: ‑ Deleted base: ‑ |