| Predicted mutation | ||||||
|---|---|---|---|---|---|---|
| evidence | seq id | position | mutation | annotation | gene | description |
| RA | NC_000913 | 1,508,221 | (G)5→4 | coding (1441/1962 nt) | rlhA → | 23S rRNA 5‑hydroxycytidine C2501 synthase |
| Read alignment evidence... | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| seq id | position | ref | new | freq | score (cons/poly) | reads | annotation | genes | product | ||
| * | NC_000913 | 1,508,217 | 0 | G | . | 98.2% | 230.4 / ‑1.8 | 55 | coding (1437/1962 nt) | rlhA | 23S rRNA 5‑hydroxycytidine C2501 synthase |
| Reads supporting (aligned to +/- strand): ref base G (1/0); new base . (29/25); total (30/25) | |||||||||||
| Fisher's exact test for biased strand distribution p-value = 1.00e+00 | |||||||||||
| Kolmogorov-Smirnov test that lower quality scores support variant p-value = 2.12e-01 | |||||||||||
TGTCAGCATCACGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCCGGGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAACCGGTTGCTGATCCTGCGCCGGTTTATCCG > NC_000913/1508079‑1508352 | tgtCAGCATCACGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCCgg > 1:225516/1‑140 (MQ=255)tgtCAGCATCACGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCCgg > 1:752871/1‑140 (MQ=255) gtCAGCATCACGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCCggg > 2:649359/1‑140 (MQ=255) cAGCATCACGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCCggggc > 1:80900/1‑139 (MQ=255) aGCATCACGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCCggggcg < 1:649359/140‑3 (MQ=255) aGCATCACGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCCggggcg < 2:807213/140‑3 (MQ=255) cATCACGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCCggggcgct < 1:1077619/140‑5 (MQ=255) tCACGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGt < 1:266452/140‑1 (MQ=255) tCACGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGt > 2:161699/1‑140 (MQ=255) aCGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGttt < 1:175348/140‑1 (MQ=255) aCGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGttt > 1:737209/1‑140 (MQ=255) gCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGt < 2:225516/140‑1 (MQ=255) aCGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCa > 1:743727/1‑140 (MQ=255) gCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCaaa < 1:574418/140‑1 (MQ=255) gCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCaaa > 2:384942/1‑140 (MQ=255) gACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGt > 2:770225/1‑140 (MQ=255) ggCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCTAACAGTCTGt > 1:794860/1‑140 (MQ=255) ggCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGt > 2:205264/1‑140 (MQ=255) tCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAAcc > 1:140353/1‑140 (MQ=255) tCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAAcc > 2:940865/1‑140 (MQ=255) tCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAAcc > 1:1069895/1‑140 (MQ=255) ccAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTccgcc > 2:126924/1‑140 (MQ=255) ccAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTccgcc > 1:601899/1‑140 (MQ=255) ccAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGAAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTccgcc > 2:758318/1‑140 (MQ=255) tAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGa < 1:940865/140‑1 (MQ=255) gCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAgct > 2:9635/1‑140 (MQ=255) ccGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAgctg > 2:513849/1‑140 (MQ=255) cGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAgctgc > 1:218928/1‑140 (MQ=255) cGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAgc < 2:666011/137‑1 (MQ=255) cGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAgc > 1:666011/1‑137 (MQ=255) cGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTT‑AACCAGTTCCGCCGTGAAgctgct < 1:161699/140‑1 (MQ=255) gAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAgctgct < 1:384942/140‑1 (MQ=255) aaaaGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGa < 1:770225/140‑1 (MQ=255) cAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGc > 1:199271/1‑140 (MQ=255) cTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTgcg < 2:80900/140‑1 (MQ=255) cTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTgcg < 2:737209/140‑1 (MQ=255) aGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTc > 2:996709/1‑140 (MQ=255) ggATGGTCTGGCAAAACTGGGGCAACCCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCt < 1:126924/140‑1 (MQ=255) ggATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCt < 2:752871/140‑1 (MQ=255) tGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGc < 2:199271/140‑1 (MQ=255) ggTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTgcg < 2:422945/131‑1 (MQ=255) ggTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTgcg > 1:422945/1‑131 (MQ=255) ggTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGcgcg < 1:104316/133‑1 (MQ=255) ggTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGcgcg > 2:104316/1‑133 (MQ=255) ggTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGcc > 1:222977/1‑140 (MQ=255) ggTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGcc > 2:566789/1‑140 (MQ=255) ggTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGcc > 2:721563/1‑140 (MQ=255) aCTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGtt < 2:203819/133‑1 (MQ=255) aCTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGtt > 1:203819/1‑133 (MQ=255) ggggCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCgg < 1:377233/140‑1 (MQ=255) ggggCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCgg < 2:1069895/140‑1 (MQ=255) ggggCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAATTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCgg < 2:802735/140‑1 (MQ=255) cccTCTATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTa > 1:285914/1‑140 (MQ=255) tctATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAAc > 2:112314/1‑140 (MQ=255) ctATTACGCCGGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAGCAGTCTGTTAAGCCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAAcc < 2:1155304/140‑1 (MQ=255) ctATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAAcc < 2:236495/140‑1 (MQ=255) tATTACGCCCGCGATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAACCg < 1:566789/140‑1 (MQ=255) gcgATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAACCGGTTGCTGATc < 1:170110/140‑1 (MQ=255) cgATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAAc < 2:745799/127‑1 (MQ=255) cgATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAAc > 1:745799/1‑127 (MQ=255) gATGTGCAAATTAATTTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAACCGGTTGCTGATCCt > 2:529277/1‑140 (MQ=255) ttaattTGCC‑GGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAACCGGTTGCTGATCCTGCGCCGGttt < 1:205264/140‑1 (MQ=255) tGCCGGGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAACCGGTTGCTGATCCTGCGCCGGTTTATCCg > 2:656848/1‑140 (MQ=255) | TGTCAGCATCACGCATACGCTGGACGGGCAGTTCGACGAAGCCAATAACGCCGAAAAAGCAATGAACAATCTGAAGGATGGTCTGGCAAAACTGGGGCAAACCCTCTATTACGCCCGCGATGTGCAAATTAATTTGCCGGGGGCGCTGTTTGTACCAAACAGTCTGTTAAACCAGTTCCGCCGTGAAGCTGCTGACATGCTGGATGCTGCGCGTCTTGCCAGTTACCAGCGCGGCAGCCGTAAACCGGTTGCTGATCCTGCGCCGGTTTATCCG > NC_000913/1508079‑1508352 |
| Alignment Legend |
|---|
Aligned base mismatch/match (shaded by quality score): ATCG/ATCG < 3 ≤ ATCG/ATCG < 22 ≤ ATCG/ATCG < 33 ≤ ATCG/ATCG < 37 ≤ ATCG/ATCG < 40 ≤ ATCG/ATCG |
Unaligned base: atcg Masked matching base: atcg Alignment gap: ‑ Deleted base: ‑ |