| Predicted mutation | ||||||
|---|---|---|---|---|---|---|
| evidence | seq id | position | mutation | annotation | gene | description |
| RA | NC_000913 | 890,085 | A→G | intergenic (‑266/‑4) | ybjL ← / → ybjM | putative transport protein YbjL/putative inner membrane protein |
| Read alignment evidence... | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| seq id | position | ref | new | freq | score (cons/poly) | reads | annotation | genes | product | ||
| * | NC_000913 | 890,085 | 0 | A | G | 98.4% | 210.6 / ‑4.5 | 62 | intergenic (‑266/‑4) | ybjL/ybjM | putative transport protein YbjL/putative inner membrane protein |
| Reads supporting (aligned to +/- strand): ref base A (1/0); new base G (33/28); total (34/28) | |||||||||||
| Fisher's exact test for biased strand distribution p-value = 1.00e+00 | |||||||||||
| Kolmogorov-Smirnov test that lower quality scores support variant p-value = 8.58e-01 | |||||||||||
ACTAGTGTAATCACATTAGGTATCAACGGCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAACGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCGGGCTGCCGGGCATCCTGAAATCGGCTTGCTATTTT > NC_000913/889949‑890221 | aCTAGTGTAATCACATTAGGTATCAACGGCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGCAAAATGTATTCGATAGACGCACTGTCAGGAGGAGCGa > 1:354992/1‑140 (MQ=255)aCTAGTGTAATCACATTAGGTATCAACGGCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGa > 1:593713/1‑140 (MQ=255)aCTAGTGTAATCACATTAGGTATCAACGGCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGa > 2:27658/1‑140 (MQ=255) tAGTGTAATCACATTATATATCTACGGCTATGTAAGTTGCGTTGGCCTTTATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGt < 2:354992/140‑1 (MQ=255) gaGTGTAATCACATTAGGTATCAACGGCTATTTGACTTGCGTTGGCCTGTATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGt < 2:337456/139‑1 (MQ=255) aTCACATTAGGTATCAACGGCTCTATGAATTCCGTCGGCTTATATTAGTATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACAt < 2:221036/140‑1 (MQ=255) aTCACATTAGGTATCAACGGCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGAGAAAAATGTGTTCGATTGACGCAGTATCAGTAGGAGCGAGTGAAACAt > 2:243816/1‑140 (MQ=255) aTTAGGTATCAACGGCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGACAGACGCACTGTCAGAAGGAGCTAGTGAAACATAaacc > 1:337456/1‑139 (MQ=255) ttAGGTATCAACGGCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATGGACGCAGAGTCAGGGGGAGCGGGTGAAACATAaacaa > 1:221036/1‑140 (MQ=255) ttAGGTATCAACGGCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAaacaa > 2:778245/1‑140 (MQ=255) ttAGGTATCAACGGCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAaacaa > 1:245572/1‑140 (MQ=255) aaCGGCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCg > 1:758979/1‑140 (MQ=255) cGGCTATATGAATTGCGTTGGCATATATTTGCATGGAGTGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCggg < 1:369936/140‑1 (MQ=255) gCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGCCGCAGTGTAAGGTGGAGCGAGTGAAGCATAAACAACGTTGGGCggggg > 2:323994/1‑140 (MQ=255) cTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGc > 2:746074/1‑140 (MQ=255) tattaaTTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAAt > 2:574602/5‑140 (MQ=255) tatGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAAt > 2:662677/1‑140 (MQ=255) gAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATctg < 1:586401/140‑1 (MQ=255) ttGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATctgctg > 1:27776/1‑140 (MQ=255) cGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAATGTTGGGCGGGGGCAATCTGCTGttt > 1:634628/1‑140 (MQ=255) gTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGtttt < 1:680888/140‑1 (MQ=255) gTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGtttt > 2:782058/1‑140 (MQ=255) ggCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTc < 2:617475/140‑1 (MQ=255) ccTATATTAGCATGGTATGCGAGGCAGCTGTATCTTATTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCct < 1:323994/140‑1 (MQ=255) ccTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCct < 2:451757/140‑1 (MQ=255) ccTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCct < 1:27658/140‑1 (MQ=255) tatTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTc > 2:540529/1‑140 (MQ=255) tatTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTc > 1:11603/1‑140 (MQ=255) gCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAGTCTGCTGTTATGTCCTCTTCATtgt > 1:346045/1‑140 (MQ=255) cATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATtgtg > 2:68017/1‑140 (MQ=255) gAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCa < 1:159174/131‑1 (MQ=255) gAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCa > 2:159174/1‑131 (MQ=255) gAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGgtgt > 2:23355/1‑140 (MQ=255) gAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGgtgt > 2:552360/1‑140 (MQ=255) gAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGgtgt > 2:40730/1‑140 (MQ=255) gAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGgtgt > 2:827252/1‑140 (MQ=255) gAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGgtgt > 2:688092/1‑140 (MQ=255) cGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGGTGGGCGGGAGCAATCTGCTGTTTTGTCCTCCTCATTGTGGTGTGCCtt > 2:248951/1‑140 (MQ=255) gCTTTATCTTACTGACCGCCACCCTTGCGCAAAATGTATTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTgg < 1:243816/140‑1 (MQ=255) cTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGTAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGTTGTGCCTTTTTCTGGc < 2:825315/140‑1 (MQ=255) tttATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCg < 1:827252/140‑1 (MQ=255) ttATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGa < 1:40730/140‑1 (MQ=255) aTCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACg < 1:778245/140‑1 (MQ=255) cTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGca < 1:683577/140‑1 (MQ=255) cTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGca < 1:662677/140‑1 (MQ=255) aCTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACAt > 1:672843/1‑140 (MQ=255) aCTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACAt > 1:546919/1‑140 (MQ=255) cGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGa < 1:51633/127‑1 (MQ=255) cGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGa > 2:51633/1‑127 (MQ=255) acacTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCt < 2:63698/140‑1 (MQ=255) cacTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCAGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCtt > 1:39724/1‑140 (MQ=255) gCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCgg > 2:827392/1‑140 (MQ=255) cGAAAAATGTGTTCGCTAGACGCAGTGTCCGGAGGAGTGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCggg < 1:248951/140‑1 (MQ=255) aaaaaTGTGTTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATGGTGGTGTGACTTATTCTGGCGACGCACATGGAAGGCGCTTTTCGGGCt > 2:233830/1‑140 (MQ=255) tgtTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCATTCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCGGGCTGCCGGGc > 2:137879/1‑140 (MQ=255) tgtTCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTGTGGGGACGCACATGAAAGGCGGTTTTCGGGCTGCCGGGc > 2:208539/1‑140 (MQ=255) tgtTCGATAGACGCAGTGTCAGGAGGAACGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTTGCGACGCACATAAAGGGCGCTTTTCGGGCTGCCGGGc > 1:266222/1‑140 (MQ=255) tCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCGGGCTGCCGGGCATc < 1:746074/140‑1 (MQ=255) tCGATAGACGCAGTGTCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCGGGCTGCCGGGCATc < 1:538849/140‑1 (MQ=255) gtgtCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCGGGCTGCCGGGCATCCTGAAATCGGCt < 2:698714/140‑1 (MQ=255) gtgtCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCGGGCTGCCGGGCATCCTGAAATCGGCt < 1:574602/140‑1 (MQ=255) gtgtCAGGAGGAGCGAGTGAAACATAAACAACGTTGGGCAGGGGCAATTTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCGGGCTGCCGGGCATCCTGAAATCGGCt < 2:245572/140‑1 (MQ=255) aggaGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCGGGCTGCCGGGCATCCTGAAATCGGCTTGCTAttt < 2:570005/140‑1 (MQ=255) ggaGCGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCGGGCTGCCGGGCATCCTGAAATCGGCTTGCTAtttt < 1:552360/140‑1 (MQ=255) | ACTAGTGTAATCACATTAGGTATCAACGGCTATATGAATTGCGTTGGCCTATATTAGCATGGAATGCGAAGCGGCTTTATCTTACTGAACGCCACACTGGCGAAAAATGTGTTCGATAGACGCAGTGTCAGGAGGAACGAGTGAAACATAAACAACGTTGGGCGGGGGCAATCTGCTGTTTTGTCCTCTTCATTGTGGTGTGCCTTTTTCTGGCGACGCACATGAAAGGCGCTTTTCGGGCTGCCGGGCATCCTGAAATCGGCTTGCTATTTT > NC_000913/889949‑890221 |
| Alignment Legend |
|---|
Aligned base mismatch/match (shaded by quality score): ATCG/ATCG < 3 ≤ ATCG/ATCG < 15 ≤ ATCG/ATCG < 33 ≤ ATCG/ATCG < 37 ≤ ATCG/ATCG < 40 ≤ ATCG/ATCG |
Unaligned base: atcg Masked matching base: atcg Alignment gap: ‑ Deleted base: ‑ |