Intuitive matrices for microbial mutation data

High quality curated mutations from related samples in organized, interactive and annotated tables

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Want to see your unpublished/private mutations on ALEDB?

Snapshot of a mutation table

⦡

Mutation Type	Observed Mutations	Unique Mutations
Single Base Substitutions	1341672	611910
Multiple Base Substitutions	94108	33234
Deletions	81838	18705
Insertions	63064	13007
Mobile Element Insertions	9096	1513
Amplifications	38003	31231
Gene Conversions	17	5
Inversions	6	1

ALEDB is the largest collection of microbial evolution mutation data in the world

1627804 instances of 709606 unique mutations from 11860 isolates across 239 unique projects

More projects added every month

Search through ALEDB to compare results from multiple experiments at once

Genetic Target:

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Ref Sequence:

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When logged in, search will also include private projects you have access to as well

Three mutation callers for triple the confidence

Industry standard tools Breseq and GATK's HaplotypeCaller for more standard mutation calls

CNVnator for larger deletions and amplification mutations

Detailed alignment and coverage reports powered by gdtools for a consistent browsing experience

Example mutation alignment reports: SNP, INS, AMP

Easily export mutation data as CSV spreadsheets

For further analysis using your favorite spreadsheet tools and scripts

Click here for an example export download

ALEDB contains data from over 93 different publications from around the world

To add your own data on ALEDB or to run your own ALE experiment
contact us here

License

Permission to use, copy, modify and distribute any part of ALEDB for educational, research and non-profit purposes, without fee, and without a written agreement is hereby granted, provided that the above copyright notice, this paragraph and the following three paragraphs appear in all copies.

Those desiring to incorporate ALEDB Models into commercial products or use for commercial purposes should contact Adam Feist at afeist@ucsd.edu and he can inform you about the appropriate tech transfer contacts.

In no event shall the University of California be liable to any party for direct, indirect, special, incidental, or consequential damages, including lost profits, arising out of the use of ALEDB, even if the University of California has been advised of the possibility of such damage.

ALEDB provided herein is on an "as is" basis, and the University of California has no obligation to provide maintenance, support, updates, enhancements, or modifications. The University of California makes no representations and extends no warranties of any kind, either implied or express, including, but not limited to, the implied warranties of merchantability or fitness for a particular purpose, or that the use of ALEDB will not infringe any patent, trademark or other rights.

ALEDB is hosted and maintained by the Systems Biology Research Group at the University of California, San Diego.