Notes

Publication:

10.1038/nature18959

ALE, flask, and isolate counts

ALE replicate Flask count Isolate count
0 1 1
1 11 22
2 11 22
3 4 8
4 11 22
5 11 22
6 5 10
7 54 107

ALE experiment mutation counts

Mutation Type Unique Observed
Single Base Substitutions 324 1392
Multiple Base Substitutions 2 8
Deletions 133 621
Insertions 42 169
Mobile Element Insertions 151 622
Amplifications 25 117
Gene Conversions 1 1
Inversions 1 3
Total 679 2933

Sample Resequencing Stats

Note: The mutation counts shown below represent unfiltered mutation sets.
ALE, Flask, Isolate Predicted Mutations Unassigned Missing Coverage Evidence Mean Coverage Total Reads Percent Mapped Mapped Reads Average Read Length
A0 F0 I1 R1 2 0 0.0 0 0.0% 0 0.0
A1 F500 I1 R1 5 0 0.0 0 0.0% 0 0.0
A1 F500 I2 R1 4 0 0.0 0 0.0% 0 0.0
A1 F1000 I1 R1 4 0 0.0 0 0.0% 0 0.0
A1 F1000 I2 R1 2 0 0.0 0 0.0% 0 0.0
A1 F1500 I1 R1 7 0 0.0 0 0.0% 0 0.0
A1 F1500 I2 R1 6 0 0.0 0 0.0% 0 0.0
A1 F2000 I1 R1 9 0 0.0 0 0.0% 0 0.0
A1 F2000 I2 R1 9 0 0.0 0 0.0% 0 0.0
A1 F5000 I1 R1 23 0 0.0 0 0.0% 0 0.0
A1 F5000 I2 R1 21 0 0.0 0 0.0% 0 0.0
A1 F10000 I1 R1 38 0 0.0 0 0.0% 0 0.0
A1 F10000 I2 R1 36 0 0.0 0 0.0% 0 0.0
A1 F15000 I1 R1 53 0 0.0 0 0.0% 0 0.0
A1 F15000 I2 R1 53 0 0.0 0 0.0% 0 0.0
A1 F20000 I1 R1 64 0 0.0 0 0.0% 0 0.0
A1 F20000 I2 R1 62 0 0.0 0 0.0% 0 0.0
A1 F30000 I1 R1 91 0 0.0 0 0.0% 0 0.0
A1 F30000 I2 R1 88 0 0.0 0 0.0% 0 0.0
A1 F40000 I1 R1 105 0 0.0 0 0.0% 0 0.0
A1 F40000 I2 R1 109 0 0.0 0 0.0% 0 0.0
A1 F50000 I1 R1 125 0 0.0 0 0.0% 0 0.0
A1 F50000 I2 R1 128 0 0.0 0 0.0% 0 0.0
A2 F500 I1 R1 3 0 0.0 0 0.0% 0 0.0
A2 F500 I2 R1 3 0 0.0 0 0.0% 0 0.0
A2 F1000 I1 R1 4 0 0.0 0 0.0% 0 0.0
A2 F1000 I2 R1 4 0 0.0 0 0.0% 0 0.0
A2 F1500 I1 R1 5 0 0.0 0 0.0% 0 0.0
A2 F1500 I2 R1 6 0 0.0 0 0.0% 0 0.0
A2 F2000 I1 R1 8 0 0.0 0 0.0% 0 0.0
A2 F2000 I2 R1 9 0 0.0 0 0.0% 0 0.0
A2 F5000 I1 R1 12 0 0.0 0 0.0% 0 0.0
A2 F5000 I2 R1 11 0 0.0 0 0.0% 0 0.0
A2 F10000 I1 R1 23 0 0.0 0 0.0% 0 0.0
A2 F10000 I2 R1 25 0 0.0 0 0.0% 0 0.0
A2 F15000 I1 R1 31 0 0.0 0 0.0% 0 0.0
A2 F15000 I2 R1 33 0 0.0 0 0.0% 0 0.0
A2 F20000 I1 R1 38 0 0.0 0 0.0% 0 0.0
A2 F20000 I2 R1 35 0 0.0 0 0.0% 0 0.0
A2 F30000 I1 R1 48 0 0.0 0 0.0% 0 0.0
A2 F30000 I2 R1 49 0 0.0 0 0.0% 0 0.0
A2 F40000 I1 R1 60 0 0.0 0 0.0% 0 0.0
A2 F40000 I2 R1 56 0 0.0 0 0.0% 0 0.0
A2 F50000 I1 R1 70 0 0.0 0 0.0% 0 0.0
A2 F50000 I2 R1 70 0 0.0 0 0.0% 0 0.0
A3 F500 I1 R1 3 0 0.0 0 0.0% 0 0.0
A3 F500 I2 R1 4 0 0.0 0 0.0% 0 0.0
A3 F1000 I1 R1 4 0 0.0 0 0.0% 0 0.0
A3 F1000 I2 R1 4 0 0.0 0 0.0% 0 0.0
A3 F1500 I1 R1 6 0 0.0 0 0.0% 0 0.0
A3 F1500 I2 R1 6 0 0.0 0 0.0% 0 0.0
A3 F2000 I1 R1 8 0 0.0 0 0.0% 0 0.0
A3 F2000 I2 R1 10 0 0.0 0 0.0% 0 0.0
A4 F500 I1 R1 2 0 0.0 0 0.0% 0 0.0
A4 F500 I2 R1 3 0 0.0 0 0.0% 0 0.0
A4 F1000 I1 R1 2 0 0.0 0 0.0% 0 0.0
A4 F1000 I2 R1 4 0 0.0 0 0.0% 0 0.0
A4 F1500 I1 R1 7 0 0.0 0 0.0% 0 0.0
A4 F1500 I2 R1 9 0 0.0 0 0.0% 0 0.0
A4 F2000 I1 R1 6 0 0.0 0 0.0% 0 0.0
A4 F2000 I2 R1 7 0 0.0 0 0.0% 0 0.0
A4 F5000 I1 R1 12 0 0.0 0 0.0% 0 0.0
A4 F5000 I2 R1 9 0 0.0 0 0.0% 0 0.0
A4 F10000 I1 R1 22 0 0.0 0 0.0% 0 0.0
A4 F10000 I2 R1 22 0 0.0 0 0.0% 0 0.0
A4 F15000 I1 R1 27 0 0.0 0 0.0% 0 0.0
A4 F15000 I2 R1 28 0 0.0 0 0.0% 0 0.0
A4 F20000 I1 R1 40 0 0.0 0 0.0% 0 0.0
A4 F20000 I2 R1 37 0 0.0 0 0.0% 0 0.0
A4 F30000 I1 R1 44 0 0.0 0 0.0% 0 0.0
A4 F30000 I2 R1 42 0 0.0 0 0.0% 0 0.0
A4 F40000 I1 R1 54 0 0.0 0 0.0% 0 0.0
A4 F40000 I2 R1 54 0 0.0 0 0.0% 0 0.0
A4 F50000 I1 R1 69 0 0.0 0 0.0% 0 0.0
A4 F50000 I2 R1 69 0 0.0 0 0.0% 0 0.0
A5 F500 I1 R1 2 0 0.0 0 0.0% 0 0.0
A5 F500 I2 R1 2 0 0.0 0 0.0% 0 0.0
A5 F1000 I1 R1 6 0 0.0 0 0.0% 0 0.0
A5 F1000 I2 R1 3 0 0.0 0 0.0% 0 0.0
A5 F1500 I1 R1 5 0 0.0 0 0.0% 0 0.0
A5 F1500 I2 R1 4 0 0.0 0 0.0% 0 0.0
A5 F2000 I1 R1 7 0 0.0 0 0.0% 0 0.0
A5 F2000 I2 R1 7 0 0.0 0 0.0% 0 0.0
A5 F5000 I1 R1 15 0 0.0 0 0.0% 0 0.0
A5 F5000 I2 R1 11 0 0.0 0 0.0% 0 0.0
A5 F10000 I1 R1 20 0 0.0 0 0.0% 0 0.0
A5 F10000 I2 R1 17 0 0.0 0 0.0% 0 0.0
A5 F15000 I1 R1 30 0 0.0 0 0.0% 0 0.0
A5 F15000 I2 R1 31 0 0.0 0 0.0% 0 0.0
A5 F20000 I1 R1 33 0 0.0 0 0.0% 0 0.0
A5 F20000 I2 R1 32 0 0.0 0 0.0% 0 0.0
A5 F30000 I1 R1 51 0 0.0 0 0.0% 0 0.0
A5 F30000 I2 R1 52 0 0.0 0 0.0% 0 0.0
A5 F40000 I1 R1 66 0 0.0 0 0.0% 0 0.0
A5 F40000 I2 R1 69 0 0.0 0 0.0% 0 0.0
A5 F50000 I1 R1 79 0 0.0 0 0.0% 0 0.0
A5 F50000 I2 R1 81 0 0.0 0 0.0% 0 0.0
A6 F500 I1 R1 3 0 0.0 0 0.0% 0 0.0
A6 F500 I2 R1 3 0 0.0 0 0.0% 0 0.0
A6 F1000 I1 R1 4 0 0.0 0 0.0% 0 0.0
A6 F1000 I2 R1 3 0 0.0 0 0.0% 0 0.0
A6 F1500 I1 R1 4 0 0.0 0 0.0% 0 0.0
A6 F1500 I2 R1 6 0 0.0 0 0.0% 0 0.0
A6 F2000 I1 R1 5 0 0.0 0 0.0% 0 0.0
A6 F2000 I2 R1 5 0 0.0 0 0.0% 0 0.0
A6 F5000 I1 R1 8 0 0.0 0 0.0% 0 0.0
A6 F5000 I2 R1 10 0 0.0 0 0.0% 0 0.0

Mutation Needle Plot


Mutation Targets

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