mutation predictions | marginal predictions | summary statistics | genome diff | command line log
|
breseq version 0.35.4 revision f352f80f4bc9
mutation predictions | marginal predictions | summary statistics | genome diff | command line log |
| Predicted mutations | ||||||
|---|---|---|---|---|---|---|
| evidence | position | mutation | freq | annotation | gene | description |
| RA | 5,144 | G→A | 68.4% | intergenic (+124/‑90) | thrC → / → yaaX | L‑threonine synthase/DUF2502 family putative periplasmic protein |
| RA | 7,905 | A→C | 9.9% | Y19D (TAC→GAC) | yaaJ ← | putative transporter |
| RA | 10,444 | G→T | 85.3% | F17L (TTC→TTA) | satP ← | succinate‑acetate transporter |
| RA | 12,901 | G→A | 100% | D247N (GAT→AAT) | dnaK → | chaperone Hsp70, with co‑chaperone DnaJ |
| RA | 13,327 | G→T | 6.3% | V389L (GTA→TTA) | dnaK → | chaperone Hsp70, with co‑chaperone DnaJ |
| RA | 29,139 | G→T | 62.1% | G256C (GGT→TGT) | dapB → | dihydrodipicolinate reductase |
| RA | 43,364 | G→T | 12.4% | P59P (CCG→CCT) | fixB → | putative electron transfer flavoprotein, NAD/FAD‑binding domain and ETFP adenine nucleotide‑binding domain‑like protein |
| RA | 43,550 | G→A | 5.8% | A121A (GCG→GCA) | fixB → | putative electron transfer flavoprotein, NAD/FAD‑binding domain and ETFP adenine nucleotide‑binding domain‑like protein |
| RA | 56,677 | G→T | 66.1% | R145S (CGC→AGC) | lptD ← | LPS assembly OM complex LptDE, beta‑barrel component |
| RA | 65,335 | G→T | 7.8% | P149Q (CCG→CAG) | polB ← | DNA polymerase II |
| RA | 72,337 | C→A | 15.7% | D484Y (GAC→TAC) | sgrR ← | transcriptional DNA‑binding transcriptional activator of sgrS sRNA |
| RA | 72,392 | G→T | 48.0% | F465L (TTC→TTA) | sgrR ← | transcriptional DNA‑binding transcriptional activator of sgrS sRNA |
| RA | 104,948 | A→T | 63.9% | E61D (GAA→GAT) | secA → | preprotein translocase subunit, ATPase |
| RA | 105,563 | C→A | 11.4% | D266E (GAC→GAA) | secA → | preprotein translocase subunit, ATPase |
| RA | 118,828 | G→T | 6.5% | D84Y (GAT→TAT) | pdhR → | pyruvate dehydrogenase complex repressor; autorepressor |
| RA | 118,873 | G→T | 87.5% | D99Y (GAC→TAC) | pdhR → | pyruvate dehydrogenase complex repressor; autorepressor |
| RA | 119,002 | G→T | 14.1% | D142Y (GAT→TAT) | pdhR → | pyruvate dehydrogenase complex repressor; autorepressor |
| RA | 123,870 | G→T | 42.7% | P563P (CCG→CCT) | aceF → | pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2 |
| RA | 142,460 | T→A | 83.3% | F298Y (TTC→TAC) | yadE → | putative polysaccharide deacetylase lipoprotein |
| RA | 147,946 | G→T | 47.1% | I47I (ATC→ATA) | yadK ← | putative fimbrial‑like adhesin protein |
| RA | 153,472 | G→T | 66.8% | intergenic (‑102/+268) | yadN ← / ← folK | putative fimbrial‑like adhesin protein/2‑amino‑4‑hydroxy‑6‑hydroxymethyldihyropteridine pyrophosphokinase |
| RA | 157,178 | C→A | 52.1% | intergenic (‑87/+91) | dksA ← / ← sfsA | transcriptional regulator of rRNA transcription, DnaK suppressor protein/sugar fermentation stimulation protein A |
| RA | 158,287 | C→A | 79.4% | D78Y (GAC→TAC) | ligT ← | 2'‑5' RNA ligase |
| RA | 158,967 | C→A | 8.7% | H126N (CAT→AAT) | hrpB → | putative ATP‑dependent helicase |
| RA | 161,171 | G→T | 8.8% | intergenic (+150/‑46) | hrpB → / → mrcB | putative ATP‑dependent helicase/fused glycosyl transferase and transpeptidase |
| RA | 170,868 | C→A | 13.3% | V168F (GTT→TTT) | hemL ← | glutamate‑1‑semialdehyde aminotransferase (aminomutase) |
| RA | 198,022 | C→A | 42.2% | R189S (CGT→AGT) | lpxD → | UDP‑3‑O‑(3‑hydroxymyristoyl)‑glucosamine N‑acyltransferase |
| RA | 230,579 | C→T | 100% | E231K (GAA→AAA) | gloB ← | hydroxyacylglutathione hydrolase |
| RA | 232,860 | G→T | 89.4% | D103Y (GAT→TAT) | dnaQ → | DNA polymerase III epsilon subunit |
| RA | 233,053 | A→C | 6.1% | D167A (GAT→GCT) | dnaQ → | DNA polymerase III epsilon subunit |
| RA | 234,994 | G→T | 17.5% | S77* (TCA→TAA) | ykfM ← | lethality reduction protein, putative inner membrane protein |
| RA | 235,010 | G→T | 13.6% | L72I (CTT→ATT) | ykfM ← | lethality reduction protein, putative inner membrane protein |
| RA | 235,019 | C→A | 15.8% | V69L (GTA→TTA) | ykfM ← | lethality reduction protein, putative inner membrane protein |
| RA | 235,022 | G→T | 15.0% | H68N (CAT→AAT) | ykfM ← | lethality reduction protein, putative inner membrane protein |
| RA | 238,195 | G→T | 71.5% | V532V (GTC→GTA) | fadE ← | acyl coenzyme A dehydrogenase |
| RA | 241,773 | A→T | 10.9% | Y174N (TAC→AAC) | yafK ← | L,D‑transpeptidase‑related protein |
| RA | 248,470 | A→C | 13.9% | intergenic (+30/‑22) | dinB → / → yafN | DNA polymerase IV/antitoxin of the YafO‑YafN toxin‑antitoxin system |
| RA | 249,629 | G→A | 13.6% | R145Q (CGA→CAA) | yafP → | putative acyl‑CoA transferase |
| RA | 281,469 | A→T | 12.4% | T122S (ACC→TCC) | yagG → | CP4‑6 prophage; putative sugar transporter |
| RA | 306,510 | G→A | 10.3% | R180W (CGG→TGG) | ecpR ← | putative transcriptional regulator for the ecp operon |
| RA | 306,949 | G→A | 16.8% | A33A (GCC→GCT) | ecpR ← | putative transcriptional regulator for the ecp operon |
| RA | 307,398 | G→A | 5.5% | intergenic (‑351/‑425) | ecpR ← / → ykgL | putative transcriptional regulator for the ecp operon/uncharacterized protein |
| RA | 312,532 | G→A | 79.6% | pseudogene (349/684 nt) | ykgA ← | pseudogene, AraC family;putative regulator; Not classified; putative ARAC‑type regulatory protein |
| RA | 319,179 | G→T | 5.3% | P377P (CCG→CCT) | ykgF → | ferridoxin‑like LutB family protein; putative electron transport chain YkgEFG component |
| RA | 320,920 | G→A | 63.3% | S52S (AGC→AGT) | ykgH ← | putative inner membrane protein |
| RA | 334,250 | G→T | 19.5% | R72L (CGT→CTT) | yahG → | DUF1116 family protein |
| RA | 339,660 | C→T | 5.2% | intergenic (+16/‑227) | yahK → / → yahL | aldehyde reductase, NADPH‑dependent, Zn‑containing, broad specificity/uncharacterized protein |
| RA | 341,060 | C→A | 16.4% | intergenic (+358/‑55) | yahL → / → yahM | uncharacterized protein/uncharacterized protein |
| RA | 351,359 | G→T | 13.8% | G243C (GGT→TGT) | codB → | cytosine transporter |
| RA | 351,447 | T→A | 6.0% | L272Q (CTG→CAG) | codB → | cytosine transporter |
| RA | 353,486 | A→T | 6.6% | intergenic (+321/+16) | codA → / ← cynR | cytosine/isoguanine deaminase/transcriptional activator of cyn operon; autorepressor |
| RA | 353,489 | C→T | 7.3% | intergenic (+324/+13) | codA → / ← cynR | cytosine/isoguanine deaminase/transcriptional activator of cyn operon; autorepressor |
| RA | 358,609 | G→T | 6.7% | I94I (ATC→ATA) | lacY ← | lactose permease |
| RA | 360,172 | T→A | 5.2% | intergenic (‑106/+489) | lacZ ← / ← lacI | pseudogene, truncated/DNA‑binding transcriptional repressor |
| RA | 360,752 | A→G | 100% | V331A (GTG→GCG) | lacI ← | DNA‑binding transcriptional repressor |
| JC | 361,139 | +GCCA | 9.6% | coding (605/1083 nt) | lacI ← | DNA‑binding transcriptional repressor |
| RA | 361,806 | G→A | 100% | intergenic (‑63/+14) | lacI ← / ← mhpR | DNA‑binding transcriptional repressor/mhp operon transcriptional activator |
| RA | 362,159 | G→T | 55.7% | I165I (ATC→ATA) | mhpR ← | mhp operon transcriptional activator |
| RA | 370,428 | T→C | 5.4% | intergenic (+91/‑487) | mhpE → / → mhpT | 4‑hyroxy‑2‑oxovalerate/4‑hydroxy‑2‑oxopentanoic acid aldolase, class I/3‑hydroxyphenylpropionic transporter |
| RA | 372,966 | G→T | 5.4% | intergenic (+199/+25) | yaiL → / ← frmB | DUF2058 family protein/S‑formylglutathione hydrolase |
| RA | 376,532 | C→A | 46.5% | pseudogene (184/416 nt) | yaiX ← | pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase |
| RA | 379,943 | C→T | 8.5% | G44R (GGA→AGA) | yaiS ← | putative PIG‑L family deacetylase |
| RA | 379,966 | G→A | 11.6% | S36L (TCG→TTG) | yaiS ← | putative PIG‑L family deacetylase |
| RA | 389,725 | G→T | 12.0% | pseudogene (1300/1449 nt) | yaiT → | pseudogene, autotransporter family;putative structure; Not classified; interrupted by IS3; putative flagellin structural protein |
| RA | 395,611 | C→A | 7.9% | D257Y (GAC→TAC) | ddlA ← | D‑alanine‑D‑alanine ligase A |
| RA | 401,692 | T→C | 6.3% | intergenic (+14/‑169) | yaiI → / → aroL | UPF0178 family protein/shikimate kinase II |
| RA | 402,340 | G→T | 80.5% | V160V (GTG→GTT) | aroL → | shikimate kinase II |
| RA | 406,075 | C→A | 86.1% | P159Q (CCG→CAG) | mak → | manno(fructo)kinase |
| RA | 411,027 | G→T | 87.0% | L61L (CTC→CTA) | sbcC ← | exonuclease, dsDNA, ATP‑dependent |
| RA | 415,485 | G→T | 7.4% | V147L (GTG→TTG) | brnQ → | branched‑chain amino acid transport system 2 carrier protein; LIV‑II transport system for Ile, Leu, and Val |
| RA | 418,958 | A→T | 6.4% | N329Y (AAT→TAT) | malZ → | maltodextrin glucosidase |
| RA | 419,663 | G→T | 38.5% | E564* (GAA→TAA) | malZ → | maltodextrin glucosidase |
| RA | 425,256 | C→T | 5.6% | P99L (CCG→CTG) | secF → | SecYEG protein translocase auxillary subunit |
| RA | 433,551 | G→T | 87.4% | S14Y (TCC→TAC) | yajO ← | 2‑carboxybenzaldehyde reductase |
| RA | 434,663 | A→C | 78.8% | I324S (ATC→AGC) | dxs ← | 1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring |
| RA | 435,336 | G→T | 70.5% | Q100K (CAG→AAG) | dxs ← | 1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring |
| RA | 437,672 | T→A | 60.9% | V223E (GTG→GAG) | thiI → | tRNA s(4)U8 sulfurtransferase |
| RA | 442,299 | G→T | 15.1% | S288* (TCG→TAG) | cyoE ← | protoheme IX farnesyltransferase |
| RA | 456,588 | G→T | 82.1% | D749Y (GAC→TAC) | lon → | DNA‑binding ATP‑dependent protease La |
| RA | 461,641 | G→A | 40.4% | V376V (GTC→GTT) | ybaE ← | putative ABC superfamily transporter periplasmic‑binding protein |
| RA | 474,138 | G→T | 81.3% | intergenic (‑65/+99) | ylaB ← / ← ylaC | putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase/DUF1449 family inner membrane protein |
| RA | 479,244 | C→A | 59.8% | A206S (GCC→TCC) | acrB ← | multidrug efflux system protein |
| RA | 480,820 | C→T | 88.6% | D86N (GAC→AAC) | acrA ← | multidrug efflux system |
| RA | 495,504 | A→T | 38.4% | intergenic (‑75/‑77) | aes ← / → gsk | acetyl esterase/inosine/guanosine kinase |
| RA | 525,424 | T→C | 9.5% | pseudogene (49/357 nt) | ylbG ← | pseudogene, DNA‑binding transcriptional regulator homology |
| RA | 530,466 | C→A | 81.8% | F365L (TTC→TTA) | gcl → | glyoxylate carboligase |
| RA | 542,200 | Δ1 bp | 69.9% | coding (65/1668 nt) | fdrA → | putative NAD(P)‑binding acyl‑CoA synthetase |
| RA | 546,491 | G→T | 79.4% | V199V (GTG→GTT) | ybcF → | putative carbonate kinase |
| RA | 549,397 | G→T | 87.3% | intergenic (‑1/+2) | lpxH ← / ← ppiB | UDP‑2,3‑diacylglucosamine pyrophosphohydrolase/peptidyl‑prolyl cis‑trans isomerase B (rotamase B) |
| RA | 553,502 | C→A | 9.2% | intergenic (‑305/‑166) | folD ← / → sfmA | bifunctional 5,10‑methylene‑tetrahydrofolate dehydrogenase/ 5,10‑methylene‑tetrahydrofolate cyclohydrolase/FimA homolog |
| RA | 565,299 | T→G | 7.7% | N314K (AAT→AAG) | ybcK → | DLP12 prophage; putative recombinase |
| RA | 578,719 | G→T | 7.9% | intergenic (+128/‑418) | tfaX → / → appY | pseudogene, DLP12 prophage;Phage or Prophage Related/global transcriptional activator; DLP12 prophage |
| RA | 579,710 | G→A | 45.1% | A192T (GCA→ACA) | appY → | global transcriptional activator; DLP12 prophage |
| RA | 581,203 | A→T | 8.0% | intergenic (‑114/‑310) | ompT ← / → pauD | DLP12 prophage; outer membrane protease VII (outer membrane protein 3b)/tRNA‑OTHER |
| RA | 583,341 | T→G | 81.5% | S33R (AGT→CGT) | ybcH ← | PRK09936 family protein |
| RA | 596,756 | G→T | 12.4% | E863* (GAG→TAG) | cusA → | copper/silver efflux system, membrane component |
| RA | 601,154 | T→A | 16.8% | L63F (TTA→TTT) | ybdF ← | DUF419 family protein |
| RA | 607,931 | G→A | 86.4% | S7F (TCC→TTC) | fepA ← | iron‑enterobactin outer membrane transporter |
| RA | 608,174 | G→A | 10.5% | intergenic (‑224/‑19) | fepA ← / → fes | iron‑enterobactin outer membrane transporter/enterobactin/ferric enterobactin esterase |
| RA | 625,282 | T→A | 5.2% | intergenic (+113/‑68) | entH → / → cstA | enterobactin synthesis proofreading thioesterase/carbon starvation protein involved in peptide utilization; APC peptide transporter family protein |
| RA | 625,364 | G→T | 44.5% | G5G (GGG→GGT) | cstA → | carbon starvation protein involved in peptide utilization; APC peptide transporter family protein |
| RA | 627,794 | G→A | 5.3% | D53N (GAC→AAC) | ybdD → | DUF466 family protein |
| RA | 632,406 | T→A | 52.2% | K223N (AAA→AAT) | ybdO ← | putative DNA‑binding transcriptional regulator |
| RA | 639,231 | G→A | 85.0% | L65F (CTT→TTT) | rnk ← | regulator of nucleoside diphosphate kinase |
| RA | 641,886 | C→A | 40.3% | E51* (GAG→TAG) | citT ← | citrate:succinate antiporter |
| RA | 647,422 | G→T | 69.4% | intergenic (‑110/‑269) | citC ← / → citA | [citrate [pro‑3S]‑lyase] ligase/sensory histidine kinase in two‑component regulatory system with CitB |
| RA | 648,056 | C→A | 84.7% | F122L (TTC→TTA) | citA → | sensory histidine kinase in two‑component regulatory system with CitB |
| RA | 652,865 | Δ1 bp | 75.7% | coding (118/210 nt) | cspE → | constitutive cold shock family transcription antitermination protein; negative regulator of cspA transcription; RNA melting protein; ssDNA‑binding protein |
| RA | 660,816 | G→A | 13.7% | V318V (GTC→GTT) | mrdB ← | cell wall shape‑determining protein |
| RA | 662,631 | C→A | 60.6% | R348L (CGC→CTC) | mrdA ← | transpeptidase involved in peptidoglycan synthesis (penicillin‑binding protein 2) |
| RA | 668,211 | C→A | 7.4% | V677F (GTT→TTT) | leuS ← | leucyl‑tRNA synthetase |
| RA | 668,351 | G→T | 5.8% | P630Q (CCG→CAG) | leuS ← | leucyl‑tRNA synthetase |
| RA | 703,476 | C→A | 5.6% | intergenic (+263/‑314) | glnS → / → chiP | glutamyl‑tRNA synthetase/chitoporin, uptake of chitosugars |
| RA | 705,588 | C→A | 63.1% | intergenic (+16/+68) | chiQ → / ← fur | chitosugar‑induced verified lipoprotein/ferric iron uptake regulon transcriptional repressor; autorepressor |
| RA | 707,409 | C→A | 17.1% | intergenic (‑55/+85) | ybfE ← / ← ybfF | LexA‑regulated protein, CopB family/acyl‑CoA esterase |
| RA | 731,316 | A→T | 7.3% | T71S (ACA→TCA) | ybfC → | putative periplasmic protein |
| RA | 738,149 | G→A | 9.4% | intergenic (‑137/‑134) | dtpD ← / → ybgI | dipeptide and tripeptide permease D/NIF3 family metal‑binding protein |
| RA | 754,572 | G→T | 83.1% | E137D (GAG→GAT) | sucA → | 2‑oxoglutarate decarboxylase, thiamine triphosphate‑binding |
| RA | 757,524 | C→A | 15.1% | R183S (CGC→AGC) | sucB → | dihydrolipoyltranssuccinase |
| RA | 759,000 | C→A | 86.2% | F177L (TTC→TTA) | sucC → | succinyl‑CoA synthetase, beta subunit |
| RA | 760,181 | G→T | 12.4% | P182P (CCG→CCT) | sucD → | succinyl‑CoA synthetase, NAD(P)‑binding, alpha subunit |
| RA | 763,080 | C→T | 7.6% | T547T (ACC→ACT) | mngA → | fused 2‑O‑a‑mannosyl‑D‑glycerate specific PTS enzymes: IIA component/IIB component/IIC component |
| RA | 766,563 | G→A | 10.0% | intergenic (+496/‑351) | mngB → / → cydA | alpha‑mannosidase/cytochrome d terminal oxidase, subunit I |
| RA | 773,443 | C→A | 8.7% | A83E (GCG→GAG) | tolB → | periplasmic protein |
| RA | 775,513 | C→T | 6.5% | Q154* (CAG→TAG) | ybgF → | periplasmic TolA‑binding protein |
| RA | 780,417 | G→T | 14.0% | T119T (ACC→ACA) | ybgS ← | putative periplasmic protein |
| RA | 788,902 | G→T | 84.6% | R115S (CGT→AGT) | modF ← | fused molybdate transporter subunits of ABC superfamily: ATP‑binding components |
| RA | 800,779 | G→T | 81.6% | E607D (GAG→GAT) | ybhJ → | putative hydratase |
| RA | 816,078 | C→G | 7.0% | intergenic (+34/‑171) | ybhL → / → ybhM | UPF0005 family inner membrane protein/UPF0005 family inner membrane protein |
| RA | 828,374 | G→T | 81.1% | V11V (GTC→GTA) | ybiA ← | DUF1768 family protein |
| RA | 832,574 | G→T | 15.4% | T256T (ACG→ACT) | ybiC → | putative dehydrogenase |
| RA | 868,618 | G→T | 12.2% | E62* (GAA→TAA) | yliE → | putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase |
| RA | 871,072 | C→A | 13.4% | V94V (GTC→GTA) | yliF → | putative membrane‑anchored diguanylate cyclase |
| RA | 874,768 | G→T | 14.5% | E191* (GAA→TAA) | yliI → | soluble aldose sugar dehydrogenase |
| RA | 876,447 | G→A | 86.7% | D89N (GAT→AAT) | dacC → | D‑alanyl‑D‑alanine carboxypeptidase (penicillin‑binding protein 6a) |
| RA | 879,085 | G→T | 81.9% | intergenic (‑241/‑44) | ybjG ← / → mdfA | undecaprenyl pyrophosphate phosphatase/multidrug efflux system protein |
| RA | 882,441 | A→T | 12.0% | S119T (TCT→ACT) | ybjJ ← | putative transporter |
| RA | 920,469 | G→T | 9.4% | G584C (GGT→TGT) | clpA → | ATPase and specificity subunit of ClpA‑ClpP ATP‑dependent serine protease, chaperone activity |
| RA | 923,312 | G→T | 11.7% | S447* (TCG→TAG) | cydC ← | fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component |
| RA | 923,339 | G→T | 25.6% | S438* (TCG→TAG) | cydC ← | fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component |
| RA | 924,296 | A→C | 9.1% | L119W (TTG→TGG) | cydC ← | fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component |
| RA | 930,998 | G→A | 5.0% | A773A (GCG→GCA) | ftsK → | DNA translocase at septal ring sorting daughter chromsomes |
| RA | 932,915 | C→A | 8.4% | R30S (CGC→AGC) | lolA → | lipoprotein chaperone |
| RA | 939,763 | C→A | 5.4% | S92* (TCG→TAG) | dmsC → | dimethyl sulfoxide reductase, anaerobic, subunit C |
| RA | 947,211 | C→A | 18.3% | P600P (CCG→CCT) | pflB ← | formate C‑acetyltransferase 1, anaerobic; pyruvate formate‑lyase 1 |
| RA | 948,890 | C→A | 13.4% | E41* (GAG→TAG) | pflB ← | formate C‑acetyltransferase 1, anaerobic; pyruvate formate‑lyase 1 |
| RA | 950,103 | T→C | 20.5% | intergenic (‑181/+225) | focA ← / ← ycaO | formate channel/ribosomal protein S12 methylthiotransferase accessory factor |
| RA | 961,946 | T→A | 8.6% | F724Y (TTT→TAT) | ycaI → | ComEC family inner membrane protein |
| RA | 968,415 | G→T | 84.4% | S148* (TCG→TAG) | ycbC ← | DUF218 superfamily protein |
| RA | 971,532 | A→T | 11.4% | Q152L (CAG→CTG) | mukE → | chromosome condensin MukBEF, MukE localization factor |
| RA | 979,650 | T→A | 8.4% | L182Q (CTG→CAG) | ycbL → | putative metal‑binding enzyme |
| RA | 1,006,218 | G→T | 18.0% | E267* (GAG→TAG) | uup → | putative transporter subunit of ABC superfamily: ATP‑binding component |
| RA | 1,011,972 | A→T | 13.4% | intergenic (‑46/+23) | fabA ← / ← ycbZ | beta‑hydroxydecanoyl thioester dehydrase/putative peptidase |
| RA | 1,012,054 | C→T | 5.7% | E568K (GAA→AAA) | ycbZ ← | putative peptidase |
| RA | 1,028,552 | A→T | 6.6% | T320S (ACT→TCT) | hyaA → | hydrogenase 1, small subunit |
| RA | 1,029,664 | C→T | 5.7% | L319L (CTG→TTG) | hyaB → | hydrogenase 1, large subunit |
| RA | 1,046,398 | C→T | 6.8% | intergenic (+412/+21) | insB1 → / ← cspH | IS1 transposase B/stress protein, member of the CspA‑family |
| RA | 1,050,246 | G→T | 17.0% | L463L (CTC→CTA) | torS ← | hybrid sensory histidine kinase in two‑component regulatory system with TorR |
| RA | 1,071,939 | C→A | 6.2% | L800L (CTG→CTT) | putA ← | fused DNA‑binding transcriptional regulator/proline dehydrogenase/pyrroline‑5‑carboxylate dehydrogenase |
| RA | 1,077,911 | A→C | 82.3% | K71N (AAA→AAC) | efeO → | inactive ferrous ion transporter EfeUOB |
| RA | 1,090,918 | T→A | 11.4% | intergenic (‑25/‑43) | insE1 ← / → ymdE | IS3 transposase A/pseudogene |
| RA | 1,106,357 | C→T | 5.4% | I13I (ATC→ATT) | opgH → | membrane glycosyltransferase; nutrient‑dependent cell size regulator, FtsZ assembly antagonist |
| RA | 1,116,964 | A→G | 81.5% | intergenic (‑21/+53) | dinI ← / ← pyrC | DNA damage‑inducible protein I/dihydro‑orotase |
| RA | 1,118,506 | A→T | 8.7% | L75Q (CTA→CAA) | yceB ← | lipoprotein, DUF1439 family |
| RA | 1,123,001 | A→C | 6.3% | Q247P (CAG→CCG) | yceM → | putative oxidoreductase |
| RA | 1,129,363 | G→A | 9.5% | A36T (GCG→ACG) | flgF → | flagellar component of cell‑proximal portion of basal‑body rod |
| RA | 1,136,758 | T→A | 10.7% | A1022A (GCA→GCT) | rne ← | fused ribonucleaseE: endoribonuclease/RNA‑binding protein/RNA degradosome binding protein |
| RA | 1,151,750 | G→T | 64.5% | R178L (CGC→CTC) | holB → | DNA polymerase III, delta prime subunit |
| RA | 1,152,278 | G→T | 84.2% | E16* (GAA→TAA) | ycfH → | putative DNase |
| RA | 1,164,408 | T→A | 6.7% | intergenic (‑120/‑121) | ycfQ ← / → bhsA | repressor for bhsA(ycfR)/biofilm, cell surface and signaling protein |
| RA | 1,192,525 | C→T | 9.9% | S155N (AGC→AAC) | ymfD ← | e14 prophage; putative SAM‑dependent methyltransferase |
| RA | 1,193,873 | G→T | 83.0% | intergenic (‑180/‑278) | ymfE ← / → lit | e14 prophage; putative inner membrane protein/e14 prophage; cell death peptidase, inhibitor of T4 late gene expression |
| RA | 1,194,365 | G→T | 16.3% | W72L (TGG→TTG) | lit → | e14 prophage; cell death peptidase, inhibitor of T4 late gene expression |
| RA | 1,197,027 | G→T | 16.1% | M25I (ATG→ATT) | ymfI → | e14 prophage; uncharacterized protein |
| RA | 1,207,977 | C→A | 13.9% | intergenic (‑518/+182) | iraM ← / ← ycgX | RpoS stabilzer during Mg starvation, anti‑RssB factor/DUF1398 family protein |
| RA | 1,210,957 | C→A | 6.9% | intergenic (‑26/‑288) | bluF ← / → ycgZ | anti‑repressor for YcgE, blue light‑responsive; FAD‑binding; has c‑di‑GMP phosphodiesterase‑like EAL domain, but does not degrade c‑di‑GMP/RcsB connector protein for regulation of biofilm and acid‑resistance |
| RA | 1,211,142 | C→T | 6.8% | intergenic (‑211/‑103) | bluF ← / → ycgZ | anti‑repressor for YcgE, blue light‑responsive; FAD‑binding; has c‑di‑GMP phosphodiesterase‑like EAL domain, but does not degrade c‑di‑GMP/RcsB connector protein for regulation of biofilm and acid‑resistance |
| RA | 1,215,174 | G→T | 42.9% | pseudogene (118/2648 nt) | ycgH → | pseudogene; putative ATP‑binding component of a transport system |
| RA | 1,217,884 | A→T | 13.1% | I69I (ATT→ATA) | ymgD ← | uncharacterized protein |
| RA | 1,220,996 | G→T | 82.1% | R181R (CGG→AGG) | minC ← | cell division inhibitor |
| RA | 1,222,207 | C→T | 8.3% | S51F (TCC→TTC) | ycgJ → | uncharacterized protein |
| RA | 1,228,591 | G→T | 80.3% | intergenic (‑105/+41) | dsbB ← / ← nhaB | oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I/sodium:proton antiporter |
| RA | 1,228,879 | A→C | 10.3% | L432R (CTG→CGG) | nhaB ← | sodium:proton antiporter |
| RA | 1,229,460 | G→T | 15.6% | F238L (TTC→TTA) | nhaB ← | sodium:proton antiporter |
| RA | 1,237,605 | C→T | 6.0% | intergenic (‑78/+17) | cvrA ← / ← ldcA | putative cation/proton antiporter/murein tetrapeptide carboxypeptidase; LD‑carboxypeptidase A |
| RA | 1,243,278 | G→A | 15.1% | S431S (AGC→AGT) | dhaM ← | putative dihydroxyacetone‑specific PTS enzymes: HPr component/EI component |
| RA | 1,247,376 | G→T | 10.2% | V285V (GTG→GTT) | dhaR → | dhaKLM operon transcription activator |
| RA | 1,282,421 | A→T | 13.8% | intergenic (+439/+101) | narI → / ← rttR | nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript |
| RA | 1,282,632 | T→A | 8.4% | noncoding (61/171 nt) M1M (ATG→TTG) † |
rttR ← tpr ← |
rtT sRNA, processed from tyrT transcript protamine‑like protein |
| RA | 1,306,244 | G→A | 7.5% | S87L (TCG→TTG) | yciA ← | acyl‑CoA esterase |
| RA | 1,322,140 | T→A | 85.3% | T159S (ACG→TCG) | btuR ← | cob(I)yrinic acid a,c‑diamide adenosyltransferase |
| RA | 1,365,202 | C→A | 12.1% | H244N (CAT→AAT) | ycjM → | alpha amylase catalytic domain family protein |
| RA | 1,365,283 | G→T | 68.4% | E271* (GAG→TAG) | ycjM → | alpha amylase catalytic domain family protein |
| RA | 1,368,566 | T→G | 16.2% | F74V (TTC→GTC) | ycjP → | inner membrane putative ABC superfamily sugar transporter permease |
| JC JC | 1,376,043 | IS5 (–) +4 bp | 100% | pseudogene (10‑13/126 nt) | ycjV → | pseudogene; putative ATP‑binding component of a transport system |
| RA | 1,377,394 | C→T | 85.2% | A275A (GCG→GCA) | ycjW ← | LacI family putative transcriptional repressor |
| RA | 1,386,008 | G→T | 64.8% | Q35K (CAG→AAG) | ycjY ← | S9 homolog non‑peptidase family protein |
| RA | 1,388,406 | G→T | 67.1% | R308L (CGC→CTC) | mppA → | murein tripeptide (L‑ala‑gamma‑D‑glutamyl‑meso‑DAP) transporter subunit |
| RA | 1,460,395 | G→A | 5.3% | pseudogene (747/2513 nt) | ydbA → | pseudogene, autotransporter homolog; interrupted by IS2 and IS30 |
| RA | 1,460,401 | G→T | 5.1% | pseudogene (753/2513 nt) | ydbA → | pseudogene, autotransporter homolog; interrupted by IS2 and IS30 |
| RA | 1,460,861 | G→A | 9.8% | pseudogene (1213/2513 nt) | ydbA → | pseudogene, autotransporter homolog; interrupted by IS2 and IS30 |
| RA | 1,460,887 | G→C | 7.8% | pseudogene (1239/2513 nt) | ydbA → | pseudogene, autotransporter homolog; interrupted by IS2 and IS30 |
| RA | 1,460,896 | C→T | 7.7% | pseudogene (1248/2513 nt) | ydbA → | pseudogene, autotransporter homolog; interrupted by IS2 and IS30 |
| RA | 1,471,707 | A→T | 48.1% | *769C (TGA→TGT) | ydbD → | PF10971 family putative periplasmic methylglyoxal resistance protein |
| RA | 1,519,349 | T→A | 84.8% | K297* (AAA→TAA) | ansP ← | L‑asparagine transporter |
| RA | 1,524,654 | G→T | 17.3% | W159L (TGG→TTG) | ydcD → | uncharacterized protein |
| RA | 1,538,906 | G→A | 10.8% | pseudogene (116/381 nt) | yddK ← | pseudogene, leucine‑rich protein; putative glycoportein |
| RA | 1,539,484 | G→A | 15.7% | pseudogene (488/951 nt) | yddK ← | pseudogene, leucine‑rich protein; putative glycoportein |
| RA | 1,543,579 | A→T | 5.0% | D641V (GAC→GTC) | fdnG → | formate dehydrogenase‑N, alpha subunit, nitrate‑inducible |
| RA | 1,544,404 | C→T | 7.6% | P916L (CCG→CTG) | fdnG → | formate dehydrogenase‑N, alpha subunit, nitrate‑inducible |
| RA | 1,548,144 | G→T | 78.7% | intergenic (‑49/+85) | adhP ← / ← maeA | ethanol‑active dehydrogenase/acetaldehyde‑active reductase/malate dehydrogenase, (decarboxylating, NAD‑requiring) (malic enzyme) |
| RA | 1,563,276 | G→T | 87.3% | H491N (CAC→AAC) | gadC ← | glutamate:gamma‑aminobutyric acid antiporter |
| RA | 1,565,497 | G→A | 90.0% | S269L (TCG→TTG) | gadB ← | glutamate decarboxylase B, PLP‑dependent |
| RA | 1,569,899 | A→G | 5.5% | S660P (TCT→CCT) | yddB ← | putative TonB‑dependent outer membrane receptor |
| RA | 1,576,869 | G→A | 10.5% | intergenic (‑88/+314) | ydeN ← / ← ydeO | putative Ser‑type periplasmic non‑aryl sulfatase/UV‑inducible global regulator, EvgA‑, GadE‑dependent |
| RA | 1,604,068 | G→T | 46.0% | T290T (ACC→ACA) | uxaB ← | altronate oxidoreductase, NAD‑dependent |
| RA | 1,607,556 | A→C | 9.2% | intergenic (‑48/+16) | glsB ← / ← sad | glutaminase 2/succinate semialdehyde dehydrogenase, NAD(P)+‑dependent |
| RA | 1,628,207 | G→A | 100% | G110E (GGA→GAA) | pinQ → | Qin prophage; putative site‑specific recombinase |
| RA | 1,634,394 | C→A | 5.4% | E77* (GAG→TAG) | ydfR ← | Qin prophage; uncharacterized protein |
| RA | 1,640,268 | A→C | 12.3% | K39Q (AAG→CAG) | ydfV → | Qin prophage; uncharacterized protein |
| RA | 1,643,394 | A→G | 7.1% | intergenic (+96/‑245) | ydfC → / → dicF | uncharacterized protein, Qin prophage/sRNA antisense regulator, inhibits ftsZ, Hfq‑dependent; Qin prophage |
| RA | 1,649,456 | C→T | 40.4% | intergenic (‑58/+148) | rspA ← / ← ynfA | bifunctional D‑altronate/D‑mannonate dehydratase/UPF0060 family inner membrane protein |
| RA | 1,652,812 | A→T | 5.6% | I163F (ATC→TTC) | ynfE → | putative selenate reductase, periplasmic |
| RA | 1,661,763 | C→A | 88.7% | P353P (CCG→CCT) | mlc ← | glucosamine anaerobic growth regulon transcriptional repressor; autorepressor |
| RA | 1,671,110 | C→A | 6.0% | D351Y (GAT→TAT) | pntA ← | pyridine nucleotide transhydrogenase, alpha subunit |
| RA | 1,679,204 | T→A | 7.7% | I230N (ATC→AAC) | tus → | inhibitor of replication at Ter, DNA‑binding protein |
| RA | 1,702,966 | T→A | 7.4% | R597R (CGT→CGA) | rsxC → | SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex |
| RA | 1,703,062 | T→A | 7.4% | R629R (CGT→CGA) | rsxC → | SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex |
| RA | 1,703,101 | C→G | 7.1% | A642A (GCC→GCG) | rsxC → | SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex |
| RA | 1,704,060 | A→T | 5.1% | Q221L (CAA→CTA) | rsxD → | SoxR iron‑sulfur cluster reduction factor component; putative membrane protein of electron transport complex |
| RA | 1,711,397 | C→T | 85.6% | R28Q (CGA→CAA) | tyrS ← | tyrosyl‑tRNA synthetase |
| RA | 1,716,193 | A→T | 6.1% | S225C (AGT→TGT) | ydhJ → | putative membrane fusion protein (MFP) of YdhJK efflux pump |
| RA | 1,726,289 | A→T | 14.2% | P982P (CCA→CCT) | lhr → | putative ATP‑dependent helicase |
| RA | 1,748,094 | T→A | 16.3% | intergenic (‑7/+14) | ydhV ← / ← ydhY | putative oxidoreductase subunit/putative 4Fe‑4S ferridoxin‑type protein; FNR, Nar, NarP‑regulated protein; putative subunit of YdhYVWXUT oxidoreductase complex |
| RA | 1,761,388 | C→A | 7.5% | A519S (GCA→TCA) | ydiJ ← | putative FAD‑linked oxidoreductase |
| RA | 1,770,281 | T→A | 68.3% | D146E (GAT→GAA) | ydiF → | putative acetyl‑CoA:acetoacetyl‑CoA transferase: alpha subunit/beta subunit |
| RA | 1,784,952 | A→G | 37.9% | F184L (TTT→CTT) | ydiU ← | UPF0061 family protein |
| RA | 1,787,044 | G→T | 5.4% | intergenic (‑56/+22) | nlpC ← / ← btuD | putative C40 clan peptidase lipoprotein/vitamin B12 transporter subunit : ATP‑binding component of ABC superfamily |
| RA | 1,802,047 | G→A | 87.6% | intergenic (+100/‑6) | ydiZ → / → yniA | uncharacterized protein/fructosamine kinase family protein |
| RA | 1,807,639 | G→A | 8.5% | intergenic (‑250/+39) | ydjO ← / ← cedA | uncharacterized protein/cell division modulator |
| RA | 1,817,655 | G→A | 5.9% | intergenic (+113/‑117) | nadE → / → cho | NAD synthetase, NH3/glutamine‑dependent/endonuclease of nucleotide excision repair |
| RA | 1,832,413 | C→A | 74.8% | L315L (CTC→CTA) | ynjC → | inner membrane putative ABC superfamily transporter permease |
| RA | 1,833,730 | C→A | 83.8% | R3S (CGT→AGT) | ynjE → | molybdopterin synthase sulfurtransferase |
| RA | 1,849,412 | T→A | 11.9% | T273S (ACT→TCT) | ydjG ← | alpha‑Keto reductase, NADH‑dependent; can use methylglyoxal as substrate |
| RA | 1,865,422 | C→A | 81.9% | R261R (CGA→AGA) | yeaI → | putative membrane‑anchored diguanylate cyclase |
| RA | 1,872,520 | G→T | 84.3% | P183P (CCG→CCT) | yeaP → | diguanylate cyclase |
| RA | 1,872,672 | A→C | 5.9% | Q234P (CAG→CCG) | yeaP → | diguanylate cyclase |
| RA | 1,909,342 | T→A | 83.5% | E150D (GAA→GAT) | proQ ← | RNA chaperone, putative ProP translation regulator |
| RA | 1,915,555 | A→C | 16.5% | Q359P (CAG→CCG) | rsmF → | 16S rRNA m(5)C1407 methyltransferase, SAM‑dependent |
| RA | 1,924,898 | T→A | 12.7% | D36V (GAT→GTT) | yebG ← | DNA damage‑inducible protein regulated by LexA |
| RA | 1,930,013 | G→A | 5.6% | L187L (CTG→TTG) | zwf ← | glucose‑6‑phosphate 1‑dehydrogenase |
| RA | 1,934,928 | G→T | 7.7% | P322Q (CCG→CAG) | mepM ← | murein DD‑endopeptidase, space‑maker hydrolase, septation protein |
| RA | 1,944,177 | C→A | 66.2% | L201L (CTG→CTT) | aspS ← | aspartyl‑tRNA synthetase |
| RA | 1,995,152 | T→A | 17.3% | E40V (GAA→GTA) | fliA ← | RNA polymerase, sigma 28 (sigma F) factor |
| RA | 2,020,166 | C→A | 61.9% | D445Y (GAC→TAC) | yedQ ← | putative membrane‑anchored diguanylate cyclase |
| RA | 2,048,571 | A→T | 8.3% | P10P (CCA→CCT) | amn → | AMP nucleosidase |
| RA | 2,064,561 | G→T | 5.8% | pseudogene (421/552 nt) | yeeP → | pseudogene, CP4‑44 prophage; 50S ribosome‑binding GTPase family;Phage or Prophage Related; putative histone |
| RA | 2,070,058 | C→A | 41.3% | A90A (GCC→GCA) | yeeS → | CP4‑44 prophage; putative DNA repair protein |
| RA | 2,078,521 | C→A | 42.8% | V162V (GTG→GTT) | yeeE ← | UPF0394 family inner membrane protein |
| RA | 2,094,530 | C→T | 5.0% | V74M (GTG→ATG) | gnd ← | 6‑phosphogluconate dehydrogenase, decarboxylating |
| RA | 2,098,995 | C→A | 83.3% | G182* (GGA→TGA) | wbbI ← | d‑Galf:alpha‑d‑Glc beta‑1,6‑galactofuranosyltransferase |
| RA | 2,114,911 | A→T | 66.8% | L42Q (CTG→CAG) | wcaJ ← | colanic biosynthesis UDP‑glucose lipid carrier transferase |
| RA | 2,120,334 | T→C | 7.0% | K113R (AAA→AGA) | wcaG ← | bifunctional GDP‑fucose synthetase: GDP‑4‑dehydro‑6‑deoxy‑D‑mannose epimerase/ GDP‑4‑dehydro‑6‑L‑deoxygalactose reductase |
| RA | 2,127,716 | G→T | 13.6% | S473* (TCG→TAG) | wzc ← | colanic acid production tyrosine‑protein kinase; autokinase; Ugd phosphorylase |
| RA | 2,129,796 | C→A | 5.6% | R310L (CGT→CTT) | wza ← | colanic acid export protein; outer membrane auxillary lipoprotein |
| RA | 2,136,421 | A→G | 20.7% | D3D (GAT→GAC) | udk ← | uridine/cytidine kinase |
| RA | 2,139,910 | G→T | 83.4% | R1055L (CGA→CTA) | yegE → | putative diguanylate cyclase |
| RA | 2,144,474 | C→A | 84.7% | intergenic (‑8/‑192) | yegI ← / → yegJ | protein kinase‑related putative non‑specific DNA‑binding protein/uncharacterized protein |
| RA | 2,170,285 | C→T | 6.4% | A133A (GCG→GCA) | gatY ← | D‑tagatose 1,6‑bisphosphate aldolase 2, catalytic subunit |
| RA | 2,170,708 | G→T | 6.3% | intergenic (‑25/+283) | gatY ← / ← fbaB | D‑tagatose 1,6‑bisphosphate aldolase 2, catalytic subunit/fructose‑bisphosphate aldolase class I |
| RA | 2,170,713 | C→A | 21.4% | intergenic (‑30/+278) | gatY ← / ← fbaB | D‑tagatose 1,6‑bisphosphate aldolase 2, catalytic subunit/fructose‑bisphosphate aldolase class I |
| RA | 2,170,724 | G→T | 24.9% | intergenic (‑41/+267) | gatY ← / ← fbaB | D‑tagatose 1,6‑bisphosphate aldolase 2, catalytic subunit/fructose‑bisphosphate aldolase class I |
| RA | 2,170,757 | T→A | 7.8% | intergenic (‑74/+234) | gatY ← / ← fbaB | D‑tagatose 1,6‑bisphosphate aldolase 2, catalytic subunit/fructose‑bisphosphate aldolase class I |
| RA | 2,178,942 | A→T | 6.2% | intergenic (‑162/+61) | thiM ← / ← rcnR | hydoxyethylthiazole kinase/transcriptional repressor of rcnA |
| RA | 2,195,449 | A→T | 82.3% | E564D (GAA→GAT) | yehI → | DUF4132 domain‑containing protein |
| RA | 2,216,296 | C→A | 67.2% | I211I (ATC→ATA) | dld → | D‑lactate dehydrogenase, FAD‑binding, NADH independent |
| RA | 2,222,684 | G→C | 5.0% | intergenic (+140/+233) | yohP → / ← dusC | uncharacterized protein/tRNA‑dihydrouridine synthase C |
| RA | 2,237,098 | G→T | 70.0% | H12N (CAT→AAT) | folE ← | GTP cyclohydrolase I |
| RA | 2,237,441 | G→T | 10.3% | R18L (CGA→CTA) | yeiG → | S‑formylglutathione hydrolase |
| RA | 2,242,501 | C→A | 12.9% | E199D (GAG→GAT) | yeiE ← | putative DNA‑binding transcriptional regulator |
| RA | 2,246,241 | G→T | 7.4% | A355S (GCG→TCG) | yeiI → | putative kinase |
| RA | 2,254,517 | C→T | 33.3% | A125T (GCC→ACC) | fruA ← | fused fructose‑specific PTS enzymes: IIBcomponent/IIC components |
| RA | 2,258,182 | A→T | 11.5% | K281* (AAG→TAG) | setB → | lactose/glucose efflux system |
| RA | 2,264,143 | G→A | 67.3% | intergenic (+119/‑62) | mepS → / → rtn | murein DD‑endopeptidase, space‑maker hydrolase, mutational suppressor of prc thermosensitivity, outer membrane lipoprotein/resistance protein for phages lambda and N4, putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase |
| RA | 2,289,374 | C→A | 81.2% | V142V (GTG→GTT) | ccmC ← | heme exporter subunit |
| RA | 2,295,611 | C→T | 9.7% | A208T (GCG→ACG) | napA ← | nitrate reductase, periplasmic, large subunit |
| RA | 2,298,467 | T→C | 5.2% | intergenic (+595/+120) | eco → / ← mqo | ecotin, a serine protease inhibitor/malate dehydrogenase, FAD/NAD(P)‑binding domain |
| RA | 2,302,650 | C→A | 8.2% | M57I (ATG→ATT) | alkB ← | oxidative demethylase of N1‑methyladenine or N3‑methylcytosine DNA lesions |
| RA | 2,305,116 | C→A | 83.9% | intergenic (‑103/+9) | apbE ← / ← ompC | putative thiamine‑synthetic flavin transferase lipoprotein/outer membrane porin protein C |
| RA | 2,352,573 | C→A | 83.9% | P353P (CCG→CCT) | rhmT ← | putative L‑rhamnonate transporter |
| RA | 2,359,673 | G→T | 82.9% | M89I (ATG→ATT) | arnB → | uridine 5'‑(beta‑1‑threo‑pentapyranosyl‑4‑ulose diphosphate) aminotransferase, PLP‑dependent |
| RA | 2,362,338 | T→A | 83.6% | L274Q (CTG→CAG) | arnA → | fused UDP‑L‑Ara4N formyltransferase/UDP‑GlcA C‑4'‑decarboxylase |
| RA | 2,370,361:1 | +G | 81.2% | coding (711/759 nt) | menH ← | 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase |
| RA | 2,370,987 | C→A | 84.8% | E29* (GAA→TAA) | menH ← | 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase |
| RA | 2,376,381 | G→A | 16.1% | A64T (GCT→ACT) | elaD → | protease, capable of cleaving an AMC‑ubiquitin model substrate |
| RA | 2,390,862 | C→A | 12.9% | V20V (GTG→GTT) | nuoH ← | NADH:ubiquinone oxidoreductase, membrane subunit H |
| RA | 2,405,946 | T→G | 81.8% | Q43P (CAG→CCG) | yfbU ← | UPF0304 family protein |
| RA | 2,407,495 | G→T | 14.5% | G183C (GGC→TGC) | ackA → | acetate kinase A and propionate kinase 2 |
| RA | 2,410,498 | G→A | 5.5% | intergenic (+128/‑62) | pta → / → yfcC | phosphate acetyltransferase/putative inner membrane transporter, C4‑dicarboxylate anaerobic carrier family |
| RA | 2,422,841 | C→A | 87.4% | D293Y (GAT→TAT) | purF ← | amidophosphoribosyltransferase |
| RA | 2,424,074 | C→T | 85.7% | D57N (GAC→AAC) | cvpA ← | colicin V production membrane protein |
| RA | 2,450,335 | C→T | 80.7% | intergenic (‑44/+159) | sixA ← / ← fadJ | phosphohistidine phosphatase/fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase |
| RA | 2,454,297 | T→G | 64.2% | E39D (GAA→GAC) | yfcZ ← | UPF0381 family protein |
| RA | 2,463,906 | C→A | 15.1% | Q433K (CAA→AAA) | gtrS → | serotype‑specific glucosyl transferase, CPS‑53 (KpLE1) prophage |
| RA | 2,463,915 | C→A | 13.6% | Q436K (CAA→AAA) | gtrS → | serotype‑specific glucosyl transferase, CPS‑53 (KpLE1) prophage |
| RA | 2,464,528 | G→A | 5.5% | pseudogene (235/291 nt) | tfaS → | pseudogene, CPS‑53 (KpLE1) prophage; tail fiber assembly protein fragment;Phage or Prophage Related |
| RA | 2,473,273 | A→T | 5.9% | K198I (AAA→ATA) | dsdA → | D‑serine dehydratase |
| RA | 2,474,418 | G→T | 80.2% | S413* (TCA→TAA) | emrY ← | putative multidrug efflux system |
| RA | 2,477,974 | C→A | 6.1% | P41Q (CCA→CAA) | evgS → | hybrid sensory histidine kinase in two‑component regulatory system with EvgA |
| RA | 2,493,151 | C→A | 10.8% | V334V (GTC→GTA) | ypdA → | sensor kinase regulating yhjX; pyruvate‑responsive YpdAB two‑component system |
| RA | 2,493,283 | C→A | 19.9% | N378K (AAC→AAA) | ypdA → | sensor kinase regulating yhjX; pyruvate‑responsive YpdAB two‑component system |
| RA | 2,520,863 | G→T | 11.3% | D187Y (GAC→TAC) | yfeH → | putative inorganic ion transporter |
| RA | 2,551,235 | C→T | 6.4% | A268A (GCG→GCA) | eutB ← | ethanolamine ammonia‑lyase, large subunit, heavy chain |
| RA | 2,553,563 | T→G | 12.7% | intergenic (+138/‑53) | intZ → / → yffL | CPZ‑55 prophage; putative phage integrase/CPZ‑55 prophage; uncharacterized protein |
| RA | 2,556,774 | G→A | 5.2% | intergenic (+298/‑177) | yffP → / → yffQ | CPZ‑55 prophage; uncharacterized protein/CPZ‑55 prophage; uncharacterized protein |
| RA | 2,576,325 | C→A | 83.3% | E171D (GAG→GAT) | nudK ← | GDP‑mannose pyrophosphatase |
| RA | 2,587,029:1 | +G | 81.9% | coding (101/699 nt) | ypfH ← | palmitoyl‑CoA esterase activity, uncertain physiological substrate |
| RA | 2,605,882 | C→A | 7.1% | S208R (AGC→AGA) | hyfR → | hydrogenase‑4 transcriptional activator |
| RA | 2,606,516 | G→T | 78.6% | D420Y (GAC→TAC) | hyfR → | hydrogenase‑4 transcriptional activator |
| RA | 2,609,187 | C→A | 51.4% | A18A (GCG→GCT) | yfgO ← | putative UPF0118 family inner membrane permease |
| RA | 2,614,168 | C→A | 79.3% | D22Y (GAT→TAT) | upp ← | uracil phosphoribosyltransferase |
| RA | 2,651,665 | G→T | 80.2% | G210G (GGC→GGA) | hscA ← | DnaK‑like molecular chaperone specific for IscU |
| RA | 2,653,668 | G→T | 12.8% | intergenic (‑20/+8) | iscU ← / ← iscS | iron‑sulfur cluster assembly scaffold protein/cysteine desulfurase (tRNA sulfurtransferase), PLP‑dependent |
| RA | 2,654,099 | C→A | 19.3% | A264A (GCG→GCT) | iscS ← | cysteine desulfurase (tRNA sulfurtransferase), PLP‑dependent |
| RA | 2,654,144 | G→T | 8.1% | I249I (ATC→ATA) | iscS ← | cysteine desulfurase (tRNA sulfurtransferase), PLP‑dependent |
| RA | 2,671,274 | C→A | 84.4% | T149T (ACG→ACT) | yphE ← | putative sugar transporter subunit of ABC superfamily, ATP‑binding component |
| RA | 2,672,639 | C→A | 5.2% | E30* (GAA→TAA) | yphF ← | putative ABC superfamily sugar transporter periplasmic‑binding protein |
| RA | 2,674,941 | G→T | 40.9% | I388I (ATC→ATA) | yphG ← | DUF4380 domain‑containing TPR repeat protein |
| RA | 2,679,933 | C→A | 16.8% | A247D (GCT→GAT) | hmp → | fused nitric oxide dioxygenase/dihydropteridine reductase 2 |
| RA | 2,681,873 | T→A | 85.7% | Q97L (CAG→CTG) | glrR ← | response regulator regulating glmY sRNA in two‑component system with sensor protein GlrK |
| RA | 2,708,587 | C→A | 14.7% | T31T (ACG→ACT) | yfiE ← | putative DNA‑binding transcriptional regulator |
| RA | 2,715,643 | G→T | 85.7% | E778* (GAA→TAA) | pka → | protein lysine acetyltransferase |
| RA | 2,718,953 | G→T | 41.0% | I51I (ATC→ATA) | kgtP ← | alpha‑ketoglutarate transporter |
| RA | 2,719,426 | T→C | 100% | intergenic (‑321/+2) | kgtP ← / ← rrfG | alpha‑ketoglutarate transporter/5S ribosomal RNA of rrnG operon |
| RA | 2,726,241 | T→A | 5.0% | K431I (AAA→ATA) | clpB ← | protein disaggregation chaperone |
| RA | 2,733,753 | C→T | 100% | E253K (GAG→AAG) | aroF ← | 3‑deoxy‑D‑arabino‑heptulosonate‑7‑phosphate synthase, tyrosine‑repressible |
| RA | 2,759,184 | C→T | 8.9% | intergenic (‑49/‑93) | yfjM ← / → rnlA | CP4‑57 prophage; uncharacterized protein/CP4‑57 prophage; RNase LS |
| RA | 2,762,594 | C→A | 6.7% | R191S (CGC→AGC) | yfjQ → | CP4‑57 prophage; uncharacterized protein |
| RA | 2,767,403 | G→A | 15.8% | D243N (GAT→AAT) | yfjW → | CP4‑57 prophage; putative inner membrane protein |
| RA | 2,771,358 | G→A | 68.5% | intergenic (+217/+147) | ypjF → / ← ypjA | CP4‑57 prophage; toxin of the YpjF‑YfjZ toxin‑antitoxin system/adhesin‑like autotransporter |
| RA | 2,771,400 | C→T | 5.4% | intergenic (+259/+105) | ypjF → / ← ypjA | CP4‑57 prophage; toxin of the YpjF‑YfjZ toxin‑antitoxin system/adhesin‑like autotransporter |
| RA | 2,775,830 | C→T | 43.5% | D86N (GAT→AAT) | ypjA ← | adhesin‑like autotransporter |
| RA | 2,777,166 | A→T | 13.4% | pseudogene (1205/1374 nt) | ypjC ← | pseudogene |
| RA | 2,802,110 | T→A | 6.5% | pseudogene (436/1178 nt) | ygaY → | pseudogene, major facilitator transporter superfamily;putative transport; Not classified; putative transport protein |
| RA | 2,804,103 | G→A | 8.2% | intergenic (+65/‑26) | ygaH → / → mprA | putative L‑valine exporter, norvaline resistance protein/transcriptional repressor of microcin B17 synthesis and multidrug efflux |
| RA | 2,811,408 | T→A | 5.6% | intergenic (‑189/+10) | argQ ← / ← argZ | tRNA‑Arg/tRNA‑Arg |
| RA | 2,825,783 | C→T | 85.2% | intergenic (‑135/‑52) | norR ← / → norV | anaerobic nitric oxide reductase DNA‑binding transcriptional activator/anaerobic nitric oxide reductase flavorubredoxin |
| RA | 2,832,598 | T→G | 11.7% | K9T (AAG→ACG) | ascG ← | asc operon transcriptional repressor; prpBC operon repressor |
| RA | 2,834,267 | A→T | 7.1% | E462V (GAG→GTG) | ascF → | fused cellobiose/arbutin/salicin‑specific PTS enzymes: IIB component/IC component |
| RA | 2,835,291 | T→G | 13.7% | C315G (TGC→GGC) | ascB → | cryptic 6‑phospho‑beta‑glucosidase |
| RA | 2,835,413 | C→A | 13.4% | I355I (ATC→ATA) | ascB → | cryptic 6‑phospho‑beta‑glucosidase |
| RA | 2,850,790 | C→A | 80.2% | I113I (ATC→ATA) | mutS → | methyl‑directed mismatch repair protein |
| RA | 2,873,087 | G→T | 86.0% | V15V (GTC→GTA) | ygbT ← | multifunctional endonuclease Cas1, CRISPR adaptation protein; DNA repair enzyme |
| RA | 2,876,760 | C→T | 79.8% | G246G (GGG→GGA) | casA ← | CRISP RNA (crRNA) containing Cascade antiviral complex protein |
| RA | 2,878,668 | G→T | 71.9% | V637V (GTC→GTA) | ygcB ← | R‑loop helicase‑annealase Cas3 needed for Cascade anti‑viral activity |
| RA | 2,890,873 | A→T | 11.4% | I119I (ATT→ATA) | ygcS ← | putative transporter |
| RA | 2,928,446 | G→T | 45.7% | A285S (GCT→TCT) | fucP → | L‑fucose transporter |
| RA | 2,931,717 | C→A | 81.7% | N307K (AAC→AAA) | fucK → | L‑fuculokinase |
| RA | 2,934,843 | G→T | 80.9% | H50N (CAT→AAT) | ygdD ← | UPF0382 family inner membrane protein |
| RA | 2,936,672 | C→A | 12.5% | intergenic (‑168/‑24) | ygdI ← / → csdA | DUF903 family verified lipoprotein/cysteine sulfinate desulfinase |
| RA | 2,979,880 | C→A | 6.5% | H225Q (CAC→CAA) | yqeG → | putative transporter |
| RA | 2,983,868 | G→T | 41.9% | intergenic (‑149/‑45) | yqeK ← / → ygeF | uncharacterized protein/pseudogene |
| RA | 2,988,774 | C→A | 20.9% | pseudogene (346/447 nt) | ygeN ← | pseudogene |
| RA | 2,989,295 | C→A | 84.8% | pseudogene (85/261 nt) | ygeN ← | pseudogene |
| RA | 2,993,211 | C→A | 83.7% | V14L (GTG→TTG) | ygeR ← | LysM domain‑containing M23 family putative peptidase; septation lipoprotein |
| RA | 3,001,919 | C→A | 20.6% | H351N (CAT→AAT) | ygeX → | 2,3‑diaminopropionate ammonia lyase, PLP‑dependent |
| RA | 3,010,725 | A→G | 12.0% | K436R (AAA→AGA) | ygfK → | putative Fe‑S subunit oxidoreductase subunit |
| RA | 3,020,228 | G→T | 6.4% | A368A (GCG→GCT) | guaD → | guanine deaminase |
| RA | 3,020,629 | C→A | 39.0% | I50I (ATC→ATA) | ygfQ → | putative purine permease |
| RA | 3,024,983 | C→G | 68.9% | G86G (GGC→GGG) | uacT → | uric acid permease |
| RA | 3,033,430 | G→T | 13.6% | D73Y (GAC→TAC) | fldB → | flavodoxin 2 |
| RA | 3,039,409 | T→G | 10.9% | intergenic (‑149/+118) | ygfF ← / ← gcvP | putative NAD(P)‑dependent oxidoreductase with NAD(P)‑binding Rossmann‑fold domain/glycine decarboxylase, PLP‑dependent, subunit (protein P) of glycine cleavage complex |
| RA | 3,044,464 | G→A | 86.7% | intergenic (‑438/+10) | gcvT ← / ← ubiI | aminomethyltransferase, tetrahydrofolate‑dependent, subunit (T protein) of glycine cleavage complex/2‑octaprenylphenol hydroxylase, FAD‑dependent |
| RA | 3,050,166 | C→A | 18.4% | intergenic (+18/‑42) | fau → / → sibC | 5‑formyltetrahydrofolate cyclo‑ligase family protein/sRNA antisense regulator of toxic IbsC protein |
| RA | 3,050,591 | C→A | 22.6% | A393A (GCG→GCT) | serA ← | D‑3‑phosphoglycerate dehydrogenase |
| RA | 3,075,114 | C→A | 86.2% | intergenic (‑120/‑158) | tktA ← / → loiP | transketolase 1, thiamine triphosphate‑binding/Phe‑Phe periplasmic metalloprotease, OM lipoprotein; low salt‑inducible; heat shock protein that binds Era |
| RA | 3,076,526 | C→A | 66.4% | D211Y (GAC→TAC) | speB ← | agmatinase |
| RA | 3,080,618 | T→A | 79.9% | V185E (GTG→GAG) | metK → | S‑adenosylmethionine synthetase |
| RA | 3,094,183 | G→A | 6.9% | intergenic (‑96/+80) | ansB ← / ← yggN | periplasmic L‑asparaginase 2/DUF2884 family putative periplasmic protein |
| RA | 3,103,319 | C→T | 8.9% | I136I (ATC→ATT) | yqgA → | DUF554 family putative inner membrane protein |
| RA | 3,105,207 | G→T | 14.1% | pseudogene (243/963 nt) | yghE ← | pseudogene, secretion pathway protein, L‑type protein homology; putative general secretion pathway for protein export (GSP) |
| RA | 3,111,434 | C→A | 81.4% | A346A (GCG→GCT) | yghJ ← | DUF4092 family putative lipoprotein peptidase |
| RA | 3,116,216 | G→T | 7.4% | R317S (CGT→AGT) | glcB ← | malate synthase G |
| RA | 3,120,216 | C→A | 85.2% | D389Y (GAT→TAT) | glcD ← | glycolate oxidase subunit, FAD‑linked |
| RA | 3,131,302 | C→A | 5.5% | D194Y (GAT→TAT) | gss ← | fused glutathionylspermidine amidase/glutathionylspermidine synthetase |
| RA | 3,151,733 | A→T | 8.8% | D242V (GAT→GTT) | yqhG → | DUF3828 family putative periplasmic protein |
| RA | 3,173,669 | G→T | 65.0% | A189A (GCG→GCT) | ygiB → | DUF1190 family protein |
| RA | 3,184,128 | C→T | 6.8% | S46S (AGC→AGT) | yqiI → | fimbrial protein |
| RA | 3,211,932 | C→A | 12.1% | V168V (GTG→GTT) | aer ← | fused signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component |
| RA | 3,243,810 | C→T | 18.9% | intergenic (+75/‑111) | yqjK → / → yqjF | uncharacterized protein/putative quinol oxidase subunit |
| RA | 3,246,908 | G→A | 9.6% | R222R (CGC→CGT) | yhaJ ← | LysR family putative transcriptional regulator |
| RA | 3,247,010 | C→A | 21.8% | P188P (CCG→CCT) | yhaJ ← | LysR family putative transcriptional regulator |
| RA | 3,252,258 | C→A | 80.0% | D251Y (GAT→TAT) | tdcG ← | L‑serine dehydratase 3, anaerobic |
| RA | 3,263,315 | T→C | 6.8% | intergenic (+354/+260) | yhaC → / ← rnpB | pentapetide repeats‑related protein/RNase P, M1 RNA component |
| RA | 3,263,460 | C→A | 5.7% | intergenic (+499/+115) | yhaC → / ← rnpB | pentapetide repeats‑related protein/RNase P, M1 RNA component |
| RA | 3,278,427 | C→A | 41.0% | C128* (TGC→TGA) | agaC → | N‑acetylgalactosamine‑specific enzyme IIC component of PTS |
| RA | 3,302,027 | G→T | 72.1% | S86* (TCG→TAG) | nlpI ← | lipoprotein involved in osmotic sensitivity and filamentation |
| RA | 3,309,359 | C→A | 5.6% | T5T (ACG→ACT) | infB ← | translation initiation factor IF‑2 |
| RA | 3,311,854 | G→T | 6.5% | intergenic (‑206/‑142) | metY ← / → argG | tRNA‑Met/argininosuccinate synthetase |
| RA | 3,314,944 | G→A | 22.7% | T10I (ACT→ATT) | yhbX ← | putative EptAB family phosphoethanolamine transferase, inner membrane protein |
| RA | 3,354,405 | C→T | 88.5% | intergenic (+430/‑130) | gltD → / → gltF | glutamate synthase, 4Fe‑4S protein, small subunit/periplasmic protein |
| RA | 3,371,372 | G→T | 49.3% | I65I (ATC→ATA) | rpsI ← | 30S ribosomal subunit protein S9 |
| RA | 3,373,985 | C→A | 84.5% | intergenic (+37/‑117) | yhcB → / → degQ | DUF1043 family inner membrane‑anchored protein/serine endoprotease, periplasmic |
| RA | 3,375,260 | G→T | 83.5% | D387Y (GAT→TAT) | degQ → | serine endoprotease, periplasmic |
| RA | 3,378,591 | G→A | 6.8% | intergenic (+59/‑306) | argR → / → yhcN | l‑arginine‑responsive arginine metabolism regulon transcriptional regulator/cadmium and peroxide resistance protein, stress‑induced |
| RA | 3,396,082 | G→T | 60.9% | R204S (CGT→AGT) | csrD ← | targeting factor for csrBC sRNA degradation |
| RA | 3,422,390 | C→A | 22.1% | intergenic (‑269/‑205) | rrsD ← / → yrdA | 16S ribosomal RNA of rrnD operon/bacterial transferase hexapeptide domain protein |
| RA | 3,423,592 | C→T | 6.1% | S202S (TCG→TCA) | aroE ← | dehydroshikimate reductase, NAD(P)‑binding |
| RA | 3,440,151 | G→T | 64.8% | I31I (ATC→ATA) | rpsN ← | 30S ribosomal subunit protein S14 |
| RA | 3,440,444 | G→T | 79.6% | S118S (TCC→TCA) | rplE ← | 50S ribosomal subunit protein L5 |
| RA | 3,455,867 | C→A | 86.5% | I55I (ATC→ATA) | gspJ → | putative general secretory pathway component, cryptic |
| RA | 3,469,887 | A→T | 8.2% | intergenic (‑88/+79) | yheO ← / ← fkpA | putative PAS domain‑containing DNA‑binding transcriptional regulator/FKBP‑type peptidyl‑prolyl cis‑trans isomerase (rotamase) |
| RA | 3,471,787 | C→A | 7.3% | D24Y (GAT→TAT) | slyD ← | FKBP‑type peptidyl prolyl cis‑trans isomerase (rotamase) |
| RA | 3,473,139 | G→T | 86.0% | I276I (ATC→ATA) | kefB ← | potassium:proton antiporter |
| RA | 3,476,265 | G→A | 5.2% | A540T (GCC→ACC) | yheS → | putative transporter subunit of ABC superfamily: ATP‑binding component |
| RA | 3,494,082 | T→A | 7.0% | W272R (TGG→AGG) | frlA → | putative fructoselysine transporter |
| RA | 3,494,195 | G→T | 17.1% | A309A (GCG→GCT) | frlA → | putative fructoselysine transporter |
| RA | 3,498,214 | T→G | 7.6% | intergenic (+72/+80) | frlR → / ← yhfS | putative DNA‑binding transcriptional regulator/FNR‑regulated pyridoxal phosphate‑dependent aminotransferase family protein |
| RA | 3,498,239 | A→C | 7.1% | intergenic (+97/+55) | frlR → / ← yhfS | putative DNA‑binding transcriptional regulator/FNR‑regulated pyridoxal phosphate‑dependent aminotransferase family protein |
| RA | 3,519,657 | G→T | 100% | intergenic (‑149/‑171) | nudE ← / → yrfF | adenosine nucleotide hydrolase; substrates include Ap3A, Ap2A, ADP‑ribose, NADH/inner membrane protein |
| RA | 3,527,522 | G→T | 7.3% | R449L (CGT→CTT) | pck → | phosphoenolpyruvate carboxykinase |
| RA | 3,530,481 | G→T | 14.4% | R104L (CGT→CTT) | greB → | transcript cleavage factor |
| RA | 3,543,959 | G→T | 87.3% | A625E (GCG→GAG) | malP ← | maltodextrin phosphorylase |
| RA | 3,552,241 | C→A | 5.1% | I205I (ATC→ATA) | rtcR → | sigma 54‑dependent transcriptional regulator of rtcBA expression |
| RA | 3,555,325 | T→C | 11.4% | intergenic (‑142/‑48) | glpE ← / → glpD | thiosulfate:cyanide sulfurtransferase (rhodanese)/sn‑glycerol‑3‑phosphate dehydrogenase, aerobic, FAD/NAD(P)‑binding |
| RA | 3,561,574 | C→A | 86.5% | W372L (TGG→TTG) | glgC ← | glucose‑1‑phosphate adenylyltransferase |
| RA | 3,603,226 | C→T | 6.0% | A217V (GCT→GTT) | yhhQ → | DUF165 family inner membrane protein |
| RA | 3,616,785 | T→C | 5.5% | *1412Q (TAA→CAA) C9C (TGT→TGC) |
rhsB → yhhH → |
Rhs family putative polymorphic toxin, putative neighboring cell growth inhibitor putative immunity protein for putative polymorphic toxin RhsB |
| RA | 3,622,519 | C→A | 44.4% | R127L (CGA→CTA) | rbbA ← | ribosome‑associated ATPase: ATP‑binding protein/ATP‑binding membrane protein |
| RA | 3,627,315 | G→T | 9.0% | pseudogene (504/1194 nt) | yhiL ← | pseudogene, DUF4049 family protein |
| RA | 3,633,969 | T→G | 11.0% | intergenic (+64/‑253) | uspA → / → dtpB | universal stress global response regulator/dipeptide and tripeptide permease B |
| RA | 3,635,421 | C→T | 11.8% | G400G (GGC→GGT) | dtpB → | dipeptide and tripeptide permease B |
| RA | 3,636,207 | T→A | 9.3% | T96S (ACT→TCT) | rsmJ ← | 16S rRNA m(2)G1516 methyltransferase, SAM‑dependent |
| RA | 3,642,571 | T→G | 6.3% | L93V (TTG→GTG) | arsB → | arsenite/antimonite transporter |
| RA | 3,657,073 | C→A | 6.3% | intergenic (+186/+177) | mdtF → / ← gadW | anaerobic multidrug efflux transporter, ArcA‑regulated/transcriptional activator of gadA and gadBC; repressor of gadX |
| RA | 3,662,801 | T→A | 5.9% | intergenic (‑253/‑151) | yhjA ← / → treF | putative cytochrome C peroxidase/cytoplasmic trehalase |
| RA | 3,664,370 | G→T | 6.7% | A473A (GCG→GCT) | treF → | cytoplasmic trehalase |
| RA | 3,675,614 | A→T | 7.1% | V398V (GTT→GTA) | dctA ← | C4‑dicarboxylic acid, orotate and citrate transporter |
| RA | 3,679,301 | T→G | 74.2% | Q1078P (CAG→CCG) | bcsC ← | cellulose synthase subunit |
| RA | 3,679,324 | C→A | 88.2% | M1070I (ATG→ATT) | bcsC ← | cellulose synthase subunit |
| RA | 3,681,219 | C→A | 39.5% | A439S (GCG→TCG) | bcsC ← | cellulose synthase subunit |
| RA | 3,698,074 | C→A | 11.2% | M16I (ATG→ATT) | dppC ← | dipeptide/heme transporter |
| RA | 3,721,485 | T→G | 9.4% | Y416S (TAC→TCC) | xylB ← | xylulokinase |
| RA | 3,738,431 | C→A | 80.8% | P90T (CCA→ACA) | yiaN → | 2,3‑diketo‑L‑gulonate TRAP transporter large permease protein |
| RA | 3,748,366 | C→A | 10.6% | V502V (GTG→GTT) | aldB ← | aldehyde dehydrogenase B |
| RA | 3,779,281 | C→G | 6.1% | A221G (GCT→GGT) | gpmM → | phosphoglycero mutase III, cofactor‑independent |
| RA | 3,785,915 | G→T | 82.4% | intergenic (‑4/+271) | kbl ← / ← yibB | glycine C‑acetyltransferase/YibB family protein, function unknown |
| RA | 3,786,742 | C→A | 9.0% | R101I (AGA→ATA) | yibB ← | YibB family protein, function unknown |
| RA | 3,810,195 | C→A | 80.1% | R54S (CGT→AGT) | yicC → | UPF0701 family protein |
| RA | 3,816,601 | A→T | 100% | H281L (CAC→CTC) | spoT → | bifunctional (p)ppGpp synthetase II/ guanosine‑3',5'‑bis pyrophosphate 3'‑pyrophosphohydrolase |
| RA | 3,818,010 | C→A | 81.5% | H46N (CAT→AAT) | trmH → | tRNA mG18‑2'‑O‑methyltransferase, SAM‑dependent |
| RA | 3,822,339 | A→C | 12.3% | Q12P (CAA→CCA) ‡ | xanP → | xanthine permease |
| RA | 3,822,340 | A→C | 16.4% | Q12H (CAA→CAC) ‡ | xanP → | xanthine permease |
| RA | 3,825,702 | C→A | 84.0% | K732N (AAG→AAT) | yicI ← | putative alpha‑glucosidase |
| RA | 3,830,311 | G→T | 68.6% | intergenic (+395/‑2) | yicT → / → setC | pseudogene/putative arabinose efflux transporter |
| RA | 3,837,177 | C→T | 44.4% | intergenic (‑28/‑147) | yicO ← / → ade | putative adenine permease/cryptic adenine deaminase |
| RA | 3,850,839 | G→T | 43.0% | P309Q (CCG→CAG) | yidJ ← | sulfatase/phosphatase superfamily protein |
| RA | 3,853,982 | T→A | 6.7% | F114I (TTT→ATT) | yidL → | AraC family putative transcriptional regulator |
| RA | 3,860,159 | C→A | 88.0% | P33P (CCG→CCT) | ibpB ← | heat shock chaperone |
| RA | 3,869,280 | G→T | 5.6% | M161I (ATG→ATT) | yidX → | putative lipoprotein |
| RA | 3,888,527 | G→T | 38.4% | L172L (CTG→CTT) | chrR → | chromate reductase, Class I, flavoprotein |
| RA | 3,897,492 | G→T | 5.2% | P489Q (CCG→CAG) | bglF ← | fused beta‑glucoside‑specific PTS enzymes: IIA component/IIB component/IIC component |
| RA | 3,907,094 | G→A | 43.4% | intergenic (‑66/+96) | glmS ← / ← glmU | L‑glutamine:D‑fructose‑6‑phosphate aminotransferase/fused N‑acetyl glucosamine‑1‑phosphate uridyltransferase/glucosamine‑1‑phosphate acetyl transferase |
| RA | 3,910,894 | C→A | 84.8% | M244I (ATG→ATT) | atpG ← | F1 sector of membrane‑bound ATP synthase, gamma subunit |
| RA | 3,915,397 | A→C | 7.2% | N5K (AAT→AAG) | atpB ← | F0 sector of membrane‑bound ATP synthase, subunit a |
| RA | 3,919,832 | T→A | 11.8% | intergenic (‑17/+73) | mioC ← / ← asnC | FMN‑binding protein MioC/transcriptional activator of asnA; autorepressor |
| RA | 3,923,700 | G→T | 8.0% | R252S (CGC→AGC) | ravA ← | hexameric AAA+ MoxR family ATPase, putative molecular chaperone |
| RA | 3,930,583 | A→T | 5.7% | intergenic (+55/‑71) | rbsB → / → rbsK | D‑ribose transporter subunit/ribokinase |
| RA | 3,960,036 | G→A | 91.6% | R87H (CGC→CAC) | rho → | transcription termination factor |
| RA | 3,991,234 | T→A | 6.5% | L231* (TTG→TAG) | yigB → | 5‑amino‑6‑(5‑phospho‑D‑ribitylamino)uracil phosphatase; pyrimidine phosphatase; riboflavin synthesis |
| RA | 3,994,247 | A→T | 86.0% | V57E (GTG→GAG) | yigE ← | DUF2233 family protein |
| RA | 3,999,888 | A→G | 5.3% | K222R (AAA→AGA) | recQ → | ATP‑dependent DNA helicase |
| RA | 4,009,705 | G→A | 78.0% | intergenic (‑176/‑86) | ysgA ← / → udp | putative carboxymethylenebutenolidase/uridine phosphorylase |
| RA | 4,049,008 | A→T | 13.4% | L231Q (CTG→CAG) | glnL ← | sensory histidine kinase in two‑component regulatory system with GlnG |
| RA | 4,056,018 | T→A | 90.6% | F138I (TTC→ATC) | yihN → | MFS transporter family protein |
| RA | 4,062,424 | G→T | 80.1% | I71I (ATC→ATA) | yihQ ← | alpha‑glucosidase |
| RA | 4,066,133 | T→G | 85.9% | S267R (AGC→CGC) | yihU ← | gamma‑hydroxybutyrate dehydrogenase, NADH‑dependent |
| RA | 4,068,208 | C→A | 85.6% | G60G (GGC→GGA) | yihW → | DeoR family putative transcriptional regulator |
| RA | 4,080,339 | C→A | 11.6% | intergenic (+130/‑23) | fdhD → / → yiiG | formate dehydrogenase formation protein/DUF3829 family lipoprotein |
| RA | 4,080,364 | G→T | 11.0% | M1M (ATG→ATT) † | yiiG → | DUF3829 family lipoprotein |
| RA | 4,094,362 | C→A | 81.8% | W181L (TGG→TTG) | cpxA ← | sensory histidine kinase in two‑component regulatory system with CpxR |
| RA | 4,096,163 | G→T | 11.8% | R139L (CGA→CTA) | cpxP → | inhibitor of the cpx response; periplasmic adaptor protein |
| RA | 4,097,822 | G→T | 64.8% | E115* (GAA→TAA) | pfkA → | 6‑phosphofructokinase I |
| RA | 4,127,022 | T→G | 79.6% | E188D (GAA→GAC) | yijF ← | DUF1287 family protein |
| RA | 4,142,369 | A→T | 18.0% | Y220N (TAC→AAC) | ppc ← | phosphoenolpyruvate carboxylase |
| RA | 4,158,250 | A→C | 5.9% | intergenic (+122/‑50) | rrsB → / → gltT | 16S ribosomal RNA of rrnB operon/tRNA‑Glu |
| RA | 4,175,869 | T→A | 12.8% | C198S (TGC→AGC) | rpoC → | RNA polymerase, beta prime subunit |
| RA | 4,176,823 | G→T | 70.5% | D516Y (GAC→TAC) | rpoC → | RNA polymerase, beta prime subunit |
| RA | 4,181,800 | G→T | 7.5% | S255* (TCG→TAG) | thiG ← | thiamine biosynthesis ThiGH complex subunit |
| RA | 4,208,920 | C→A | 7.7% | R133S (CGT→AGT) | aceK → | isocitrate dehydrogenase kinase/phosphatase |
| RA | 4,211,803 | G→A | 63.7% | P205S (CCT→TCT) | arpA ← | ankyrin repeat protein |
| RA | 4,214,112 | C→A | 6.6% | T119T (ACC→ACA) | metH → | homocysteine‑N5‑methyltetrahydrofolate transmethylase, B12‑dependent |
| RA | 4,230,913 | A→T | 70.7% | W424R (TGG→AGG) | xylE ← | D‑xylose transporter |
| RA | 4,258,903 | G→T | 5.6% | S13Y (TCT→TAT) | yjbS ← | uncharacterized protein |
| RA | 4,271,152 | G→T | 12.4% | M415I (ATG→ATT) | yjcE → | putative cation/proton antiporter |
| RA | 4,273,158 | A→T | 14.3% | intergenic (‑155/+23) | yjcF ← / ← actP | pentapeptide repeats protein/acetate transporter |
| RA | 4,274,926 | A→C | 5.3% | I72M (ATT→ATG) | yjcH ← | DUF485 family inner membrane protein |
| RA | 4,290,080 | G→T | 59.7% | I256I (ATC→ATA) | mdtP ← | outer membrane factor of efflux pump |
| RA | 4,291,537 | G→T | 14.1% | I453I (ATC→ATA) | mdtO ← | membrane translocase (MDR) of MdtNOP efflux pump, PET family |
| RA | 4,295,572 | C→T | 5.2% | E281E (GAG→GAA) | yjcS ← | metallo‑beta‑lactamase superfamily protein |
| RA | 4,295,721 | A→G | 10.7% | Y232H (TAC→CAC) | yjcS ← | metallo‑beta‑lactamase superfamily protein |
| RA | 4,297,846 | C→A | 100% | M150I (ATG→ATT) | alsE ← | allulose‑6‑phosphate 3‑epimerase |
| RA | 4,303,256 | G→T | 19.0% | V30V (GTG→GTT) | rpiB → | ribose 5‑phosphate isomerase B/allose 6‑phosphate isomerase |
| RA | 4,303,614 | T→A | 59.9% | *150R (TGA→AGA) | rpiB → | ribose 5‑phosphate isomerase B/allose 6‑phosphate isomerase |
| RA | 4,306,969 | T→A | 37.7% | N23Y (AAC→TAC) | phnM ← | ribophosphonate triphosphate hydrolase |
| RA | 4,308,595 | C→A | 5.7% | E277* (GAG→TAG) | phnJ ← | carbon‑phosphorus lyase, SAM‑dependent |
| RA | 4,312,246 | C→A | 42.1% | intergenic (‑7/+14) | phnF ← / ← phnE | putative DNA‑binding transcriptional regulator of phosphonate uptake and biodegradation/defective phosphonate ABC transporter permease;transport; Transport of small molecules: Anions; membrane channel protein component of Pn transporter; membrane component of ABC superfamily |
| RA | 4,349,636 | A→T | 5.6% | I71I (ATT→ATA) | cadB ← | putative lysine/cadaverine transporter |
| RA | 4,374,805 | G→T | 5.9% | G384C (GGT→TGT) | yjeM → | putative transporter |
| RA | 4,380,814 | C→A | 5.3% | A171A (GCG→GCT) | rsgA ← | ribosome small subunit‑dependent GTPase A |
| RA | 4,382,806 | T→A | 41.7% | Q360L (CAA→CTA) | queG ← | epoxyqueuosine reductase, cobalamine‑stimulated; queosine biosynthesis |
| RA | 4,383,318 | G→T | 5.5% | V189V (GTC→GTA) | queG ← | epoxyqueuosine reductase, cobalamine‑stimulated; queosine biosynthesis |
| RA | 4,388,902 | G→T | 87.6% | A558A (GCG→GCT) | mutL → | methyl‑directed mismatch repair protein |
| RA | 4,396,598 | A→T | 87.4% | E43V (GAA→GTA) | rnr → | exoribonuclease R, RNase R |
| RA | 4,434,159 | G→A | 5.1% | L77L (CTG→CTA) | tamB → | translocation and assembly module for autotransporter export, inner membrane subunit |
| RA | 4,436,661 | C→A | 12.4% | N911K (AAC→AAA) | tamB → | translocation and assembly module for autotransporter export, inner membrane subunit |
| RA | 4,458,254 | T→A | 86.4% | V271V (GTT→GTA) | mgtA → | magnesium transporter |
| RA | 4,458,609 | G→T | 86.9% | D390Y (GAT→TAT) | mgtA → | magnesium transporter |
| RA | 4,464,572 | G→T | 44.4% | intergenic (+38/‑107) | bdcR → / → tabA | transcriptional repressor for divergent bdcA/biofilm modulator regulated by toxins; DUF386 family protein, cupin superfamily |
| RA | 4,466,937 | A→C | 5.0% | T562P (ACT→CCT) | yjgL → | uncharacterized protein |
| RA | 4,469,550 | G→A | 61.6% | A2T (GCT→ACT) | yjgN → | DUF898 family inner membrane protein |
| RA | 4,470,017 | G→A | 86.9% | M157I (ATG→ATA) | yjgN → | DUF898 family inner membrane protein |
| RA | 4,489,542 | A→T | 50.5% | pseudogene (810/942 nt) | yjgX ← | pseudogene fragment |
| RA | 4,495,002 | C→A | 5.2% | F376L (TTC→TTA) | yjhB → | putative transporter |
| RA | 4,510,428 | G→T | 10.9% | intergenic (‑287/+60) | yjhU ← / ← yjhF | putative DNA‑binding transcriptional regulator; KpLE2 phage‑like element/putative transporter |
| RA | 4,511,877 | G→A | 38.6% | intergenic (‑40/+67) | yjhF ← / ← yjhG | putative transporter/putative dehydratase |
| RA | 4,512,693 | T→A | 80.1% | K407* (AAG→TAG) | yjhG ← | putative dehydratase |
| RA | 4,525,234 | G→A | 78.4% | pseudogene (415/1029 nt) | yjhR → | pseudogene, helicase family; putative frameshift suppressor |
| RA | 4,531,143 | A→T | 87.9% | I124F (ATT→TTT) | fimB → | tyrosine recombinase/inversion of on/off regulator of fimA |
| RA | 4,546,084 | G→A | 8.1% | H18H (CAC→CAT) | yjiC ← | uncharacterized protein |
| RA | 4,556,296 | C→T | 46.4% | Q256Q (CAG→CAA) | yjiN ← | zinc‑type alcohol dehydrogenase‑like protein |
| RA | 4,562,043 | C→A | 89.8% | intergenic (+311/‑188) | yjiS → / → yjiT | DUF1127 family protein/pseudogene |
| RA | 4,584,381 | G→T | 84.1% | I53I (ATC→ATA) | yjjL ← | L‑galactonate transporter |
| RA | 4,588,471 | G→A | 5.2% | A263V (GCG→GTG) | opgB ← | phosphoglycerol transferases I and II |
| RA | 4,601,014 | T→C | 49.8% | intergenic (+194/‑199) | prfC → / → osmY | peptide chain release factor RF‑3/periplasmic protein |
| RA | 4,603,125 | A→C | 7.2% | T300P (ACG→CCG) | yjjU → | putative patatin‑like family phospholipase |
| RA | 4,618,148 | C→A | 6.2% | F339L (TTC→TTA) | nadR → | trifunctional protein: nicotinamide mononucleotide adenylyltransferase, ribosylnicotinamide kinase, transcriptional repressor |
| RA | 4,618,167 | G→A | 5.9% | E346K (GAG→AAG) | nadR → | trifunctional protein: nicotinamide mononucleotide adenylyltransferase, ribosylnicotinamide kinase, transcriptional repressor |
| RA | 4,626,235 | G→T | 43.1% | E138* (GAA→TAA) | creB → | response regulator in two‑component regulatory system with CreC |
| RA | 4,629,622 | C→A | 8.2% | A168S (GCC→TCC) | arcA ← | response regulator in two‑component regulatory system with ArcB or CpxA |
| Unassigned missing coverage evidence | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| seq id | start | end | size | ←reads | reads→ | gene | description | |||
| * | * | ÷ | CP009273 | 373854 | 375106 | 1253 | 179 [177] | [177] 179 | frmA–[frmR] | frmA,[frmR] |
| * | * | ÷ | CP009273 | 4100606 | 4101515 | 910 | 180 [178] | [178] 179 | [cdh]–tpiA | [cdh],tpiA |
| Unassigned new junction evidence | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| seq id | position | reads (cov) | reads (cov) | score | skew | freq | annotation | gene | product | ||
| * | ? | CP009273 | 360104 = | 197 (0.740) | 190 (0.710) | 106/276 | NT | 49.1% | intergenic (‑38/+557) | lacZ/lacI | pseudogene, truncated/DNA‑binding transcriptional repressor |
| ? | CP009273 | = 360286 | NA (NA) | intergenic (‑220/+375) | lacZ/lacI | pseudogene, truncated/DNA‑binding transcriptional repressor | |||||
| * | ? | CP009273 | = 360278 | NA (NA) | 6545 (26.090) +TTAATTAA |
193/260 | NT | 95.8% | intergenic (‑212/+383) | lacZ/lacI | pseudogene, truncated/DNA‑binding transcriptional repressor |
| ? | CP009273 | = 361823 | 306 (1.150) | coding (831/834 nt) | mhpR | mhp operon transcriptional activator | |||||
| * | ? | CP009273 | 360652 = | 289 (1.080) | 6203 (35.050) +46 bp |
182/184 | NT | 97.3% | intergenic (‑586/+9) | lacZ/lacI | pseudogene, truncated/DNA‑binding transcriptional repressor |
| ? | CP009273 | = 1317577 | 234 (0.880) | coding (101/882 nt) | yciV | PHP domain protein | |||||
| * | ? | CP009273 | 376716 = | NA (NA) | 89 (0.330) | 59/276 | NT | 34.8% | intergenic (‑1/‑91) | yaiX/insC1 | pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase/IS2 repressor TnpA |
| ? | CP009273 | = 386403 | 167 (0.630) | pseudogene (697/1458 nt) | yaiT | pseudogene, autotransporter family;putative structure; Not classified; interrupted by IS3; putative flagellin structural protein | |||||
| * | ? | CP009273 | 376716 = | NA (NA) | 231 (0.870) | 127/276 | NT | 93.9% | intergenic (‑1/‑91) | yaiX/insC1 | pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase/IS2 repressor TnpA |
| ? | CP009273 | 566411 = | 15 (0.060) | coding (63/552 nt) | ybcL | inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family | |||||
| * | ? | CP009273 | = 378046 | NA (NA) | 120 (0.450) | 75/276 | NT | 42.3% | intergenic (+11/+1) | insD1/yaiX | IS2 transposase TnpB/pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase |
| ? | CP009273 | 386399 = | 164 (0.620) | pseudogene (693/1458 nt) | yaiT | pseudogene, autotransporter family;putative structure; Not classified; interrupted by IS3; putative flagellin structural protein | |||||
| * | ? | CP009273 | = 378046 | NA (NA) | 277 (1.040) | 128/276 | NT | 94.5% | intergenic (+11/+1) | insD1/yaiX | IS2 transposase TnpB/pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase |
| ? | CP009273 | = 566415 | 16 (0.060) | coding (67/552 nt) | ybcL | inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family | |||||
| * | ? | CP009273 | 692319 = | 260 (0.980) | 33 (0.140) +GAAGAAACAATC |
4/252 | NT | 12.1% | intergenic (‑33/+2) | glnW/glnU | tRNA‑Gln/tRNA‑Gln |
| ? | CP009273 | = 692590 | 266 (1.000) | intergenic (‑1/+379) | metT/asnB | tRNA‑Met/asparagine synthetase B | |||||
| * | ? | CP009273 | 777033 = | 189 (0.710) | 82 (0.310) +G |
7/274 | NT | 28.6% | noncoding (1/76 nt) | lysQ | tRNA‑Lys |
| ? | CP009273 | = 2514488 | 224 (0.840) | noncoding (216/1345 nt) | IS186 | repeat region | |||||
| * | ? | CP009273 | 1203246 = | 11 (0.040) | 186 (0.790) | 107/244 | NT | 93.8% | coding (290/630 nt) | stfP | e14 prophage; uncharacterized protein |
| ? | CP009273 | 1205075 = | 15 (0.060) | pseudogene (1/501 nt) | stfE | pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related | |||||
| * | ? | CP009273 | = 1203261 | 9 (0.030) | 226 (0.960) | 113/244 | NT | 95.2% | coding (305/630 nt) | stfP | e14 prophage; uncharacterized protein |
| ? | CP009273 | = 1205058 | 15 (0.060) | pseudogene (18/501 nt) | stfE | pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related | |||||
| * | ? | CP009273 | 1635219 = | 41 (0.160) | 230 (0.880) | 129/272 | NT | 84.9% | intergenic (‑377/+377) | essQ/cspB | Qin prophage; putative S lysis protein/Qin prophage; cold shock protein |
| ? | CP009273 | = 2063752 | NA (NA) | noncoding (1/1331 nt) | IS2 | repeat region | |||||
| * | ? | CP009273 | = 1635223 | 41 (0.150) | 209 (0.780) | 112/276 | NT | 83.6% | intergenic (‑381/+373) | essQ/cspB | Qin prophage; putative S lysis protein/Qin prophage; cold shock protein |
| ? | CP009273 | = 1645805 | NA (NA) | intergenic (+11/‑3) | insD1/intQ | IS2 transposase TnpB;IS, phage, Tn; Transposon‑related functions; extrachromosomal; transposon related/pseudogene, Qin prophage; phage integrase family;Phage or Prophage Related | |||||
| * | ? | CP009273 | = 2811301 | 196 (0.740) | 11 (0.050) | 11/236 | NT | 6.2% | intergenic (‑82/+117) | argQ/argZ | tRNA‑Arg/tRNA‑Arg |
| ? | CP009273 | 2811851 = | 167 (0.730) | noncoding (58/77 nt) | argV | tRNA‑Arg | |||||
| * | ? | CP009273 | = 4532507 | 234 (0.880) | 13 (0.050) | 11/258 | NT | 5.1% | intergenic (+57/‑425) | fimE/fimA | tyrosine recombinase/inversion of on/off regulator of fimA/major type 1 subunit fimbrin (pilin) |
| ? | CP009273 | = 4532803 | 270 (1.080) | intergenic (+353/‑129) | fimE/fimA | tyrosine recombinase/inversion of on/off regulator of fimA/major type 1 subunit fimbrin (pilin) | |||||