breseq  version 0.35.4  revision f352f80f4bc9
mutation predictions | marginal predictions | summary statistics | genome diff | command line log

Predicted mutations
evidence position mutation freq annotation gene description
RA 5,144 G→A 100% intergenic (+124/‑90) thrC → / → yaaX L‑threonine synthase/DUF2502 family putative periplasmic protein
RA 10,444 G→T 94.6% F17L (TTC→TTA satP ← succinate‑acetate transporter
RA 12,901 G→A 100% D247N (GAT→AAT)  dnaK → chaperone Hsp70, with co‑chaperone DnaJ
RA 23,203 G→T 6.3% V271V (GTG→GTT ileS → isoleucyl‑tRNA synthetase
RA 25,013 G→T 25.2% D875Y (GAC→TAC)  ileS → isoleucyl‑tRNA synthetase
RA 25,546 G→T 54.2% D114Y (GAC→TAC)  lspA → prolipoprotein signal peptidase (signal peptidase II)
RA 29,139 G→T 94.8% G256C (GGT→TGT)  dapB → dihydrodipicolinate reductase
RA 49,840 G→T 79.9% A6A (GCG→GCT folA → dihydrofolate reductase
RA 55,590 G→T 62.2% T507K (ACG→AAG)  lptD ← LPS assembly OM complex LptDE, beta‑barrel component
RA 56,677 G→T 92.6% R145S (CGC→AGC)  lptD ← LPS assembly OM complex LptDE, beta‑barrel component
RA 61,087 G→T 7.8% I726I (ATC→ATA rapA ← RNA polymerase remodeling/recycling factor ATPase; RNA polymerase‑associated, ATP‑dependent RNA translocase
RA 79,882 G→T 10.8% V45V (GTC→GTA leuA ← 2‑isopropylmalate synthase
RA 80,123 C→T 46.3% G25S (GGC→AGC)  leuL ← leu operon leader peptide
RA 81,562 C→A 55.8% I236I (ATC→ATA leuO → global transcription factor
RA 97,521 C→A 90.4% A90A (GCC→GCA murC → UDP‑N‑acetylmuramate:L‑alanine ligase
RA 103,467 G→T 92.6% D142Y (GAT→TAT)  lpxC → UDP‑3‑O‑acyl N‑acetylglucosamine deacetylase
RA 104,561 G→T 93.6% A124S (GCG→TCG)  secM → regulator of secA translation
RA 109,800 A→T 8.5% intergenic (‑94/‑131) coaE ← / → guaC dephospho‑CoA kinase/GMP reductase
RA 118,873 G→T 94.3% D99Y (GAC→TAC)  pdhR → pyruvate dehydrogenase complex repressor; autorepressor
RA 132,632 A→T 12.4% V107E (GTG→GAG)  speE ← spermidine synthase (putrescine aminopropyltransferase)
RA 142,460 T→A 100% F298Y (TTC→TAC)  yadE → putative polysaccharide deacetylase lipoprotein
RA 153,472 G→T 92.9% intergenic (‑102/+268) yadN ← / ← folK putative fimbrial‑like adhesin protein/2‑amino‑4‑hydroxy‑6‑hydroxymethyldihyropteridine pyrophosphokinase
RA 158,287 C→A 94.2% D78Y (GAC→TAC)  ligT ← 2'‑5' RNA ligase
RA 161,068 A→C 27.7% intergenic (+47/‑149) hrpB → / → mrcB putative ATP‑dependent helicase/fused glycosyl transferase and transpeptidase
RA 186,810 T→A 7.9% G150G (GGT→GGA rpsB → 30S ribosomal subunit protein S2
RA 210,546 C→A 7.9% V23F (GTT→TTT)  yaeP ← UPF0253 family protein
RA 230,579 C→T 100% E231K (GAA→AAA)  gloB ← hydroxyacylglutathione hydrolase
RA 232,860 G→T 92.3% D103Y (GAT→TAT)  dnaQ → DNA polymerase III epsilon subunit
RA 234,984 G→T 18.7% I80I (ATC→ATA ykfM ← lethality reduction protein, putative inner membrane protein
RA 234,994 G→T 28.1% S77* (TCA→TAA)  ykfM ← lethality reduction protein, putative inner membrane protein
RA 235,006 G→T 14.0% T73K (ACG→AAG)  ykfM ← lethality reduction protein, putative inner membrane protein
RA 235,010 G→T 24.7% L72I (CTT→ATT)  ykfM ← lethality reduction protein, putative inner membrane protein
RA 235,019 C→A 32.8% V69L (GTA→TTA)  ykfM ← lethality reduction protein, putative inner membrane protein
RA 235,022 G→T 25.0% H68N (CAT→AAT)  ykfM ← lethality reduction protein, putative inner membrane protein
RA 235,036 G→T 23.1% S63Y (TCC→TAC)  ykfM ← lethality reduction protein, putative inner membrane protein
RA 238,195 G→T 93.7% V532V (GTC→GTA fadE ← acyl coenzyme A dehydrogenase
RA 255,882 A→T 11.0% intergenic (‑71/‑217) phoE ← / → proB outer membrane phosphoporin protein E/gamma‑glutamate kinase
RA 260,931 T→A 5.4% intergenic (‑14/+84) yafX ← / ← ykfF CP4‑6 prophage; uncharacterized protein/CP4‑6 prophage; uncharacterized protein
RA 274,735 A→T 55.4% pseudogene (138/348 nt) afuB ← pseudogene, CP4‑6 prophage; ABC transporter permease family;Phage or Prophage Related
RA 280,433 G→T 9.6% G508C (GGC→TGC)  yagF → CP4‑6 prophage; dehydratase family protein
RA 308,217 A→T 6.5% V3V (GTT→GTA ykgO ← RpmJ‑like protein
RA 312,532 G→A 90.9% pseudogene (349/684 nt) ykgA ← pseudogene, AraC family;putative regulator; Not classified; putative ARAC‑type regulatory protein
RA 320,920 G→A 93.5% S52S (AGC→AGT ykgH ← putative inner membrane protein
RA 321,223 C→A 62.6% intergenic (‑148/+65) ykgH ← / ← betA putative inner membrane protein/choline dehydrogenase, a flavoprotein
RA 327,515 G→T 19.2% intergenic (+308/‑567) betT → / → yahA choline transporter of high affinity/c‑di‑GMP‑specific phosphodiesterase
RA 344,800 G→T 32.6% E136D (GAG→GAT prpB → 2‑methylisocitrate lyase
RA 345,384 G→C 5.0% intergenic (+101/‑339) prpB → / → prpC 2‑methylisocitrate lyase/2‑methylcitrate synthase
RA 345,428 T→C 5.8% intergenic (+145/‑295) prpB → / → prpC 2‑methylisocitrate lyase/2‑methylcitrate synthase
RA 353,486 A→T 7.7% intergenic (+321/+16) codA → / ← cynR cytosine/isoguanine deaminase/transcriptional activator of cyn operon; autorepressor
RA 353,489 C→T 7.3% intergenic (+324/+13) codA → / ← cynR cytosine/isoguanine deaminase/transcriptional activator of cyn operon; autorepressor
RA 353,517 T→C 5.4% G295G (GGA→GGG cynR ← transcriptional activator of cyn operon; autorepressor
RA 360,114 A→T 6.3% intergenic (‑48/+547) lacZ ← / ← lacI pseudogene, truncated/DNA‑binding transcriptional repressor
RA 360,157 T→G 6.3% intergenic (‑91/+504) lacZ ← / ← lacI pseudogene, truncated/DNA‑binding transcriptional repressor
RA 360,752 A→G 100% V331A (GTG→GCG)  lacI ← DNA‑binding transcriptional repressor
RA 361,806 G→A 100% intergenic (‑63/+14) lacI ← / ← mhpR DNA‑binding transcriptional repressor/mhp operon transcriptional activator
RA 362,159 G→T 93.5% I165I (ATC→ATA mhpR ← mhp operon transcriptional activator
RA 363,890 G→T 7.4% M349I (ATG→ATT mhpA → 3‑(3‑hydroxyphenyl)propionate hydroxylase
RA 369,273 G→T 5.5% A299A (GCG→GCT mhpF → acetaldehyde‑CoA dehydrogenase II, NAD‑binding
RA 396,883 A→G 46.4% Q14Q (CAA→CAG iraP → anti‑RssB factor, RpoS stabilzer during Pi starvation; anti‑adapter protein
RA 400,819 A→C 12.5% V94V (GTT→GTG proC ← pyrroline‑5‑carboxylate reductase, NAD(P)‑binding
RA 402,340 G→T 91.1% V160V (GTG→GTT aroL → shikimate kinase II
RA 406,075 C→A 94.3% P159Q (CCG→CAG)  mak → manno(fructo)kinase
RA 411,027 G→T 100% L61L (CTC→CTA sbcC ← exonuclease, dsDNA, ATP‑dependent
RA 421,799 C→A 49.1% I69I (ATC→ATA tgt → tRNA‑guanine transglycosylase
RA 433,551 G→T 89.9% S14Y (TCC→TAC)  yajO ← 2‑carboxybenzaldehyde reductase
RA 434,663 A→C 100% I324S (ATC→AGC)  dxs ← 1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring
RA 435,336 G→T 100% Q100K (CAG→AAG)  dxs ← 1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring
RA 437,672 T→A 92.7% V223E (GTG→GAG)  thiI → tRNA s(4)U8 sulfurtransferase
RA 442,849 C→A 10.0% A105S (GCG→TCG)  cyoE ← protoheme IX farnesyltransferase
RA 444,489 G→A 90.8% R537C (CGT→TGT)  cyoB ← cytochrome o ubiquinol oxidase subunit I
RA 456,298 T→A 94.2% L652Q (CTG→CAG)  lon → DNA‑binding ATP‑dependent protease La
RA 456,588 G→T 93.4% D749Y (GAC→TAC)  lon → DNA‑binding ATP‑dependent protease La
RA 474,138 G→T 100% intergenic (‑65/+99) ylaB ← / ← ylaC putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase/DUF1449 family inner membrane protein
RA 475,805 C→A 91.6% A120A (GCG→GCT tomB ← Hha toxicity attenuator; conjugation‑related protein
RA 479,244 C→A 93.5% A206S (GCC→TCC)  acrB ← multidrug efflux system protein
RA 480,820 C→T 92.8% D86N (GAC→AAC)  acrA ← multidrug efflux system
RA 481,667 G→A 87.1% A151T (GCG→ACG)  acrR → transcriptional repressor
RA 507,331 G→A 14.2% D79N (GAT→AAT)  glsA → glutaminase 1
RA 510,357 A→T 9.2% I291I (ATT→ATA qmcA ← PHB domain membrane‑anchored putative protease
RA 523,244 G→T 10.7% E70* (GAA→TAA)  ybbC → putative immunity protein
RA 530,466 C→A 93.2% F365L (TTC→TTA gcl → glyoxylate carboligase
RA 534,666 G→A 12.2% D22N (GAT→AAT)  allB → allantoinase
RA 542,200 Δ1 bp 100% coding (65/1668 nt) fdrA → putative NAD(P)‑binding acyl‑CoA synthetase
RA 544,713 G→T 14.9% D301Y (GAT→TAT)  ylbE → NO‑induced DUF1116 protein
RA 546,491 G→T 94.1% V199V (GTG→GTT ybcF → putative carbonate kinase
RA 549,397 G→T 93.4% intergenic (‑1/+2) lpxH ← / ← ppiB UDP‑2,3‑diacylglucosamine pyrophosphohydrolase/peptidyl‑prolyl cis‑trans isomerase B (rotamase B)
RA 550,786 G→T 14.2% A240A (GCG→GCT cysS → cysteinyl‑tRNA synthetase
RA 568,099 G→T 8.0% E60* (GAA→TAA)  ybcN → DLP12 prophage; uncharacterized protein
RA 576,998 G→T 53.6% pseudogene (189/309 nt) aaaD → pseudogene; DLP12 prophage; tail fiber assembly protein family;Phage or Prophage Related
RA 581,203 A→T 94.2% intergenic (‑114/‑310) ompT ← / → pauD DLP12 prophage; outer membrane protease VII (outer membrane protein 3b)/tRNA‑OTHER
RA 583,341 T→G 94.7% S33R (AGT→CGT)  ybcH ← PRK09936 family protein
RA 607,931 G→A 93.7% S7F (TCC→TTC)  fepA ← iron‑enterobactin outer membrane transporter
RA 625,364 G→T 82.9% G5G (GGG→GGT cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 630,088 G→T 18.0% A349A (GCG→GCT ybdL → methionine aminotransferase, PLP‑dependent
RA 631,333 G→A 5.1% N231N (AAC→AAT ybdN ← PAPS reductase‑like domain protein
RA 637,236 C→T 8.4% D30N (GAT→AAT)  uspG ← universal stress protein UP12
RA 639,231 G→A 93.9% L65F (CTT→TTT)  rnk ← regulator of nucleoside diphosphate kinase
RA 647,422 G→T 92.8% intergenic (‑110/‑269) citC ← / → citA [citrate [pro‑3S]‑lyase] ligase/sensory histidine kinase in two‑component regulatory system with CitB
RA 647,509 T→C 92.8% intergenic (‑197/‑182) citC ← / → citA [citrate [pro‑3S]‑lyase] ligase/sensory histidine kinase in two‑component regulatory system with CitB
RA 648,056 C→A 91.5% F122L (TTC→TTA citA → sensory histidine kinase in two‑component regulatory system with CitB
RA 652,865 Δ1 bp 89.1% coding (118/210 nt) cspE → constitutive cold shock family transcription antitermination protein; negative regulator of cspA transcription; RNA melting protein; ssDNA‑binding protein
RA 654,624 T→G 5.6% intergenic (+18/+83) tatE → / ← lipA TatABCE protein translocation system subunit/lipoate synthase
RA 662,108 A→T 82.8% V522V (GTT→GTA mrdA ← transpeptidase involved in peptidoglycan synthesis (penicillin‑binding protein 2)
RA 662,631 C→A 100% R348L (CGC→CTC)  mrdA ← transpeptidase involved in peptidoglycan synthesis (penicillin‑binding protein 2)
RA 704,018 G→T 7.5% D77Y (GAT→TAT)  chiP → chitoporin, uptake of chitosugars
RA 705,588 C→A 93.6% intergenic (+16/+68) chiQ → / ← fur chitosugar‑induced verified lipoprotein/ferric iron uptake regulon transcriptional repressor; autorepressor
RA 708,114 C→A 5.0% D49Y (GAT→TAT)  ybfF ← acyl‑CoA esterase
RA 724,497 A→G 8.1% intergenic (‑220/‑93) kdpF ← / → ybfA potassium ion accessory transporter subunit/DUF2517 family protein
RA 724,813 A→T 91.4% intergenic (+17/‑226) ybfA → / → rhsC DUF2517 family protein/Rhs family putative polymorphic toxin
RA 725,270 T→A 5.5% Y78N (TAC→AAC)  rhsC → Rhs family putative polymorphic toxin
RA 733,004 G→T 5.6% pseudogene (724/1137 nt) ybfL → pseudogene, DDE domain transposase family;putative factor; Not classified; putative receptor protein
RA 745,893 G→T 6.0% S578* (TCG→TAG)  ybgQ ← putative outer membrane protein
RA 754,572 G→T 90.7% E137D (GAG→GAT sucA → 2‑oxoglutarate decarboxylase, thiamine triphosphate‑binding
RA 758,030 C→A 7.2% I351I (ATC→ATA sucB → dihydrolipoyltranssuccinase
RA 759,000 C→A 100% F177L (TTC→TTA sucC → succinyl‑CoA synthetase, beta subunit
RA 764,517 G→A 5.2% D362N (GAC→AAC)  mngB → alpha‑mannosidase
RA 776,694 T→A 5.3% intergenic (+16/‑131) lysY → / → lysZ tRNA‑Lys/tRNA‑Lys
RA 788,902 G→T 93.3% R115S (CGT→AGT)  modF ← fused molybdate transporter subunits of ABC superfamily: ATP‑binding components
RA 800,488 G→T 49.1% V510V (GTG→GTT ybhJ → putative hydratase
RA 800,779 G→T 100% E607D (GAG→GAT ybhJ → putative hydratase
RA 816,078 C→G 12.2% intergenic (+34/‑171) ybhL → / → ybhM UPF0005 family inner membrane protein/UPF0005 family inner membrane protein
RA 828,374 G→T 92.6% V11V (GTC→GTA ybiA ← DUF1768 family protein
RA 832,445 G→T 63.8% P213P (CCG→CCT ybiC → putative dehydrogenase
RA 833,505 G→T 8.0% intergenic (‑124/+141) ybiJ ← / ← ybiI DUF1471 family putative periplasmic protein/DksA‑type zinc finger protein
RA 837,110 C→T 8.2% intergenic (‑123/+142) fiu ← / ← mcbA catecholate siderophore receptor Fiu/colanic acid mucoidy stimulation protein
RA 842,546 A→C 8.8% P10P (CCT→CCG glnP ← glutamine transporter subunit
RA 843,299 C→A 41.1% W54C (TGG→TGT glnH ← glutamine transporter subunit
RA 876,447 G→A 100% D89N (GAT→AAT)  dacC → D‑alanyl‑D‑alanine carboxypeptidase (penicillin‑binding protein 6a)
RA 879,085 G→T 100% intergenic (‑241/‑44) ybjG ← / → mdfA undecaprenyl pyrophosphate phosphatase/multidrug efflux system protein
RA 895,180 G→T 10.4% intergenic (+79/+120) rlmC → / ← artJ 23S rRNA m(5)U747 methyltransferase, SAM‑dependent/arginine binding protein, periplasmic
RA 916,133 G→T 5.9% A111S (GCC→TCC)  macB → fused macrolide transporter subunits of ABC superfamily: ATP‑binding component/membrane component
RA 918,501 G→A 6.8% D45N (GAC→AAC)  clpS → regulatory protein for ClpA substrate specificity
RA 924,905 G→T 11.6% S505* (TCG→TAG)  cydD ← fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component
RA 925,160 G→T 47.7% S420* (TCA→TAA)  cydD ← fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component
RA 939,763 C→A 8.2% S92* (TCG→TAG)  dmsC → dimethyl sulfoxide reductase, anaerobic, subunit C
RA 941,177 G→A 10.8% intergenic (‑164/‑150) ycaC ← / → ycaD putative isochorismatase family hydrolase/putative MFS‑type transporter
RA 943,573 G→T 42.4% A297S (GCC→TCC)  ycaM → putative transporter
RA 954,475 C→A 14.4% R70S (CGT→AGT)  aroA → 5‑enolpyruvylshikimate‑3‑phosphate synthetase
RA 960,043 G→T 15.3% G90C (GGC→TGC)  ycaI → ComEC family inner membrane protein
RA 968,415 G→T 100% S148* (TCG→TAG)  ycbC ← DUF218 superfamily protein
RA 975,610 G→T 6.7% V1277L (GTG→TTG)  mukB → chromosome condensin MukBEF, ATPase and DNA‑binding subunit
RA 982,997 G→T 5.6% intergenic (‑559/+44) ompF ← / ← asnS outer membrane porin 1a (Ia;b;F)/asparaginyl tRNA synthetase
RA 1,035,483 G→T 5.1% M244I (ATG→ATT cbdB → cytochrome bd‑II oxidase, subunit II
RA 1,048,928 C→A 39.2% E903* (GAA→TAA)  torS ← hybrid sensory histidine kinase in two‑component regulatory system with TorR
RA 1,049,407 G→T 51.1% T743K (ACG→AAG)  torS ← hybrid sensory histidine kinase in two‑component regulatory system with TorR
RA 1,055,901 A→T 6.6% Q397L (CAA→CTA)  torA → trimethylamine N‑oxide (TMAO) reductase I, catalytic subunit
RA 1,077,911 A→C 100% K71N (AAA→AAC efeO → inactive ferrous ion transporter EfeUOB
RA 1,084,103 A→T 44.8% L404* (TTA→TAA)  pgaB ← poly‑beta‑1,6‑N‑acetyl‑D‑glucosamine (PGA) N‑deacetylase outer membrane export lipoprotein
RA 1,116,964 A→G 100% intergenic (‑21/+53) dinI ← / ← pyrC DNA damage‑inducible protein I/dihydro‑orotase
RA 1,118,506 A→T 8.3% L75Q (CTA→CAA)  yceB ← lipoprotein, DUF1439 family
RA 1,144,835 G→A 13.2% M207I (ATG→ATA fabH → 3‑oxoacyl‑[acyl‑carrier‑protein] synthase III
RA 1,147,750 A→T 7.0% H119L (CAC→CTC)  fabF → 3‑oxoacyl‑[acyl‑carrier‑protein] synthase II
RA 1,151,711 C→A 6.3% A165E (GCG→GAG)  holB → DNA polymerase III, delta prime subunit
RA 1,151,750 G→T 91.2% R178L (CGC→CTC)  holB → DNA polymerase III, delta prime subunit
RA 1,152,278 G→T 93.9% E16* (GAA→TAA)  ycfH → putative DNase
RA 1,193,873 G→T 100% intergenic (‑180/‑278) ymfE ← / → lit e14 prophage; putative inner membrane protein/e14 prophage; cell death peptidase, inhibitor of T4 late gene expression
RA 1,197,734 C→T 5.1% R219K (AGA→AAA)  cohE ← e14 prophage; repressor protein phage e14
RA 1,211,169 C→A 58.5% intergenic (‑238/‑76) bluF ← / → ycgZ anti‑repressor for YcgE, blue light‑responsive; FAD‑binding; has c‑di‑GMP phosphodiesterase‑like EAL domain, but does not degrade c‑di‑GMP/RcsB connector protein for regulation of biofilm and acid‑resistance
RA 1,219,533 A→G 90.8% intergenic (+170/+202) ycgI → / ← minE pseudogene/cell division topological specificity factor
RA 1,220,996 G→T 100% R181R (CGG→AGG)  minC ← cell division inhibitor
RA 1,224,292 G→A 92.6% D8N (GAT→AAT)  ycgN → UPF0153 family cysteine cluster protein
RA 1,226,292 T→A 82.8% C24S (TGT→AGT)  umuD → DNA polymerase V, subunit D
RA 1,228,591 G→T 93.6% intergenic (‑105/+41) dsbB ← / ← nhaB oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I/sodium:proton antiporter
RA 1,266,181 C→G 9.8% intergenic (+265/+24) rdlC → / ← chaA sRNA antisense regulator affects LdrC translation; proposed addiction module in LDR‑C repeat, with toxic peptide LdrC/calcium/sodium:proton antiporter
RA 1,277,786 G→A 64.0% D823N (GAC→AAC)  narG → nitrate reductase 1, alpha subunit
RA 1,282,421 A→G 7.1% intergenic (+439/+101) narI → / ← rttR nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript
RA 1,305,621 G→A 5.7% P92P (CCG→CCA tonB → membrane spanning protein in TonB‑ExbB‑ExbD transport complex
RA 1,309,158 G→A 12.4% I108I (ATC→ATT yciE ← putative rubrerythrin/ferritin‑like metal‑binding protein
RA 1,317,200 G→T 11.1% Q2K (CAA→AAA)  trpE ← component I of anthranilate synthase
RA 1,322,140 T→A 100% T159S (ACG→TCG)  btuR ← cob(I)yrinic acid a,c‑diamide adenosyltransferase
RA 1,337,533 G→T 64.0% A18E (GCA→GAA)  osmB ← lipoprotein
RA 1,339,148 C→T 7.4% G618S (GGT→AGT)  gmr ← cyclic‑di‑GMP phosphodiesterase; csgD regulator; modulator of Rnase II stability
RA 1,345,918 C→A 5.4% D34Y (GAT→TAT)  ycjD ← DUF559 family endonuclease‑related protein
RA 1,355,349 T→A 6.4% intergenic (‑184/‑28) puuA ← / → puuD glutamate‑‑putrescine ligase/gamma‑glutamyl‑gamma‑aminobutyrate hydrolase
RA 1,365,283 G→T 100% E271* (GAG→TAG)  ycjM → alpha amylase catalytic domain family protein
RA 1,374,303 T→C 5.7% R721R (CGT→CGC ycjT → putative family 65 glycosyl hydrolase
JC JC 1,376,043 IS5 (–) +4 bp 100% pseudogene (10‑13/126 nt) ycjV → pseudogene; putative ATP‑binding component of a transport system
RA 1,377,394 C→T 100% A275A (GCG→GCA ycjW ← LacI family putative transcriptional repressor
RA 1,386,008 G→T 93.6% Q35K (CAG→AAG)  ycjY ← S9 homolog non‑peptidase family protein
RA 1,388,406 G→T 94.8% R308L (CGC→CTC)  mppA → murein tripeptide (L‑ala‑gamma‑D‑glutamyl‑meso‑DAP) transporter subunit
RA 1,389,205 G→A 5.2% A325A (GCC→GCT ynaI ← mechanosensitive channel protein, very small conductance
RA 1,403,313 C→T 14.0% intergenic (+23/‑73) ydaN → / → fnrS putative Zn(II) transporter/FNR‑activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq‑dependent; mediates negative FNR regulation
RA 1,424,234 C→A 61.4% S310* (TCA→TAA)  stfR → Rac prophage; putative tail fiber protein
JC JC 1,428,894 IS2 (–) +5 bp 69.8% intergenic (‑413/+317) ynaE ← / ← ttcC cold shock protein, Rac prophage/pseudogene, prophage Rac integration site ttcA duplication;Phage or Prophage Related
RA 1,439,518 C→A 40.4% S737S (TCC→TCA ydbH → putative membrane‑anchored protein, function unknown
RA 1,454,724 G→T 44.6% G472C (GGT→TGT)  paaH → 3‑hydroxyadipyl‑CoA dehydrogenase, NAD+‑dependent
RA 1,460,752 C→T 5.1% pseudogene (1104/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,472,138 G→T 8.6% A87A (GCG→GCT ynbA → inner membrane protein
RA 1,495,078 G→T 9.3% V83V (GTG→GTT tehA → potassium‑tellurite ethidium and proflavin transporter
RA 1,501,734 G→T 13.4% D233Y (GAT→TAT)  ydcP → putative peptidase
RA 1,519,349 T→A 100% K297* (AAA→TAA)  ansP ← L‑asparagine transporter
RA 1,521,540 T→C 9.7% intergenic (+131/‑619) yncH → / → rhsE IPR020099 family protein/pseudogene, Rhs family protein
RA 1,534,850 G→T 6.6% L666L (CTC→CTA narZ ← nitrate reductase 2 (NRZ), alpha subunit
RA 1,548,144 G→T 94.7% intergenic (‑49/+85) adhP ← / ← maeA ethanol‑active dehydrogenase/acetaldehyde‑active reductase/malate dehydrogenase, (decarboxylating, NAD‑requiring) (malic enzyme)
RA 1,555,079 C→T 5.3% P36P (CCG→CCA ddpB ← D‑ala‑D‑ala transporter subunit
RA 1,563,276 G→T 100% H491N (CAC→AAC)  gadC ← glutamate:gamma‑aminobutyric acid antiporter
RA 1,565,497 G→A 100% S269L (TCG→TTG)  gadB ← glutamate decarboxylase B, PLP‑dependent
RA 1,575,339 G→T 58.9% F481L (TTC→TTA ydeN ← putative Ser‑type periplasmic non‑aryl sulfatase
RA 1,589,490 C→T 5.7% pseudogene (2755/5323 nt) yneO ← pseudogene, AidA homolog
RA 1,603,440 G→A 61.1% intergenic (‑161/+46) yneE ← / ← uxaB bestrophin family putative inner membrane protein/altronate oxidoreductase, NAD‑dependent
RA 1,620,961 T→G 52.7% Q226P (CAA→CCA)  dcp ← dipeptidyl carboxypeptidase II
RA 1,623,755 T→G 8.3% L472F (TTA→TTC ydfI ← putative NAD‑dependent D‑mannonate oxidoreductase
RA 1,628,207 G→A 100% G110E (GGA→GAA)  pinQ → Qin prophage; putative site‑specific recombinase
RA 1,633,239 A→G 6.7% intergenic (‑315/+48) cspI ← / ← rzpQ Qin prophage; cold shock protein/Rz‑like protein, Qin prophage
RA 1,640,634 G→T 15.1% intergenic (+175/‑28) ydfV → / → flxA Qin prophage; uncharacterized protein/Qin prophage; uncharacterized protein
RA 1,653,713 T→A 18.7% V463E (GTG→GAG)  ynfE → putative selenate reductase, periplasmic
RA 1,661,763 C→A 100% P353P (CCG→CCT mlc ← glucosamine anaerobic growth regulon transcriptional repressor; autorepressor
RA 1,670,108 A→C 5.8% V170V (GTT→GTG pntB ← pyridine nucleotide transhydrogenase, beta subunit
RA 1,679,816 C→A 6.8% D344Y (GAC→TAC)  fumC ← fumarate hydratase (fumarase C),aerobic Class II
RA 1,696,612 A→T 89.8% E41D (GAA→GAT add → adenosine deaminase
RA 1,703,062 T→A 10.7% R629R (CGT→CGA rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,703,071 A→T 7.2% A632A (GCA→GCT rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,703,101 C→G 8.0% A642A (GCC→GCG rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,711,397 C→T 92.1% R28Q (CGA→CAA)  tyrS ← tyrosyl‑tRNA synthetase
RA 1,732,014 C→A 8.3% intergenic (‑212/‑87) ynhF ← / → purR stress response membrane/transcriptional repressor, hypoxanthine‑binding
RA 1,754,950 T→A 46.4% I367F (ATT→TTT)  sufD ← component of SufBCD Fe‑S cluster assembly scaffold
RA 1,770,281 T→A 100% D146E (GAT→GAA ydiF → putative acetyl‑CoA:acetoacetyl‑CoA transferase: alpha subunit/beta subunit
RA 1,802,047 G→A 93.3% intergenic (+100/‑6) ydiZ → / → yniA uncharacterized protein/fructosamine kinase family protein
RA 1,823,835 A→C 7.9% W53G (TGG→GGG)  astD ← succinylglutamic semialdehyde dehydrogenase
RA 1,823,843 A→C 8.5% F50C (TTT→TGT)  astD ← succinylglutamic semialdehyde dehydrogenase
RA 1,825,763 C→A 44.3% A159A (GCG→GCT astC ← succinylornithine transaminase, PLP‑dependent
RA 1,832,413 C→A 91.0% L315L (CTC→CTA ynjC → inner membrane putative ABC superfamily transporter permease
RA 1,833,730 C→A 100% R3S (CGT→AGT)  ynjE → molybdopterin synthase sulfurtransferase
RA 1,859,009 T→G 8.3% intergenic (+18/+30) yeaD → / ← yeaE D‑hexose‑6‑phosphate epimerase‑like protein/aldo‑keto reductase, methylglyoxal to acetol, NADPH‑dependent
RA 1,861,773 T→A 13.6% I203I (ATT→ATA yeaG → protein kinase, endogenous substrate unidentified; autokinase
RA 1,865,422 C→A 100% R261R (CGA→AGA)  yeaI → putative membrane‑anchored diguanylate cyclase
RA 1,872,520 G→T 92.4% P183P (CCG→CCT yeaP → diguanylate cyclase
RA 1,897,318 T→A 5.9% intergenic (+42/‑21) manX → / → manY fused mannose‑specific PTS enzymes: IIA component/IIB component/mannose‑specific enzyme IIC component of PTS
RA 1,899,442 C→T 10.5% R129C (CGT→TGT)  yobD → UPF0266 family inner membrane protein
RA 1,902,474 T→A 16.4% intergenic (‑626/+44) yobF ← / ← yebO DUF2527 family heat‑induced protein/putative inner membrane protein
RA 1,909,342 T→A 100% E150D (GAA→GAT proQ ← RNA chaperone, putative ProP translation regulator
RA 1,931,363 G→T 9.2% R152L (CGT→CTT)  yebK → putative DNA‑binding transcriptional regulator
RA 1,944,177 C→A 94.4% L201L (CTG→CTT aspS ← aspartyl‑tRNA synthetase
RA 1,948,689 G→A 10.5% intergenic (+19/+146) cmoB → / ← torZ tRNA (cmo5U34)‑carboxymethyltransferase, carboxy‑SAM‑dependent/trimethylamine N‑oxide reductase system III, catalytic subunit
RA 1,969,291 G→T 90.1% I97I (ATC→ATA cheA ← fused chemotactic sensory histidine kinase in two‑component regulatory system with CheB and CheY: sensory histidine kinase/signal sensing protein
RA 1,986,289 T→A 61.1% N4Y (AAT→TAT)  pgsA ← phosphatidylglycerophosphate synthetase
RA 1,997,314 G→T 39.7% intergenic (‑227/‑39) fliC ← / → fliD flagellar filament structural protein (flagellin)/flagellar filament capping protein
RA 1,999,632 G→T 36.6% intergenic (+73/‑5) fliT → / → amyA putative flagellar synthesis and assembly chaperone/cytoplasmic alpha‑amylase
RA 2,020,166 C→A 93.5% D445Y (GAC→TAC)  yedQ ← putative membrane‑anchored diguanylate cyclase
RA 2,035,090 C→A 44.5% Q79K (CAG→AAG)  zinT → zinc and cadmium binding protein, periplasmic
RA 2,035,236 A→T 20.5% K127N (AAA→AAT zinT → zinc and cadmium binding protein, periplasmic
RA 2,050,206 A→G 13.5% intergenic (+210/‑133) amn → / → yeeN AMP nucleosidase/UPF0082 family protein
RA 2,067,248 C→A 5.5% S743R (AGC→AGA flu → CP4‑44 prophage; antigen 43 (Ag43) phase‑variable biofilm formation autotransporter
RA 2,074,680 A→T 60.3% W22R (TGG→AGG)  sbmC ← DNA gyrase inhibitor
RA 2,098,995 C→A 100% G182* (GGA→TGA)  wbbI ← d‑Galf:alpha‑d‑Glc beta‑1,6‑galactofuranosyltransferase
RA 2,100,755 C→T 6.1% V352V (GTG→GTA glf ← UDP‑galactopyranose mutase, FAD/NAD(P)‑binding
RA 2,104,927 C→A 13.6% A177A (GCG→GCT rfbD ← dTDP‑4‑dehydrorhamnose reductase subunit, NAD(P)‑binding, of dTDP‑L‑rhamnose synthase
RA 2,107,730 C→A 7.1% E27* (GAG→TAG)  wcaN ← putative regulatory subunit for GalU
RA 2,108,219:1 +A 100% coding (1159/1395 nt) wcaM ← colanic acid biosynthesis protein
RA 2,114,911 A→T 94.4% L42Q (CTG→CAG)  wcaJ ← colanic biosynthesis UDP‑glucose lipid carrier transferase
RA 2,124,159 C→A 12.0% A67A (GCG→GCT wcaD ← putative colanic acid polymerase
RA 2,139,910 G→T 94.8% R1055L (CGA→CTA)  yegE → putative diguanylate cyclase
RA 2,144,474 C→A 100% intergenic (‑8/‑192) yegI ← / → yegJ protein kinase‑related putative non‑specific DNA‑binding protein/uncharacterized protein
RA 2,149,603 A→T 45.3% E287V (GAA→GTA)  mdtB → multidrug efflux system, subunit B
RA 2,154,191 G→T 11.9% A775A (GCG→GCT mdtC → multidrug efflux system, subunit C
RA 2,168,487 A→T 30.8% D14E (GAT→GAA gatA ← galactitol‑specific enzyme IIA component of PTS
RA 2,168,795 C→A 89.6% D336Y (GAT→TAT)  gatZ ← D‑tagatose 1,6‑bisphosphate aldolase 2, subunit
RA 2,169,117 A→T 7.1% D228E (GAT→GAA gatZ ← D‑tagatose 1,6‑bisphosphate aldolase 2, subunit
RA 2,170,713 C→A 30.3% intergenic (‑30/+278) gatY ← / ← fbaB D‑tagatose 1,6‑bisphosphate aldolase 2, catalytic subunit/fructose‑bisphosphate aldolase class I
RA 2,170,724 G→T 26.7% intergenic (‑41/+267) gatY ← / ← fbaB D‑tagatose 1,6‑bisphosphate aldolase 2, catalytic subunit/fructose‑bisphosphate aldolase class I
RA 2,170,757 T→A 13.4% intergenic (‑74/+234) gatY ← / ← fbaB D‑tagatose 1,6‑bisphosphate aldolase 2, catalytic subunit/fructose‑bisphosphate aldolase class I
RA 2,173,594 C→A 8.3% L7L (CTC→CTA yegU → ADP‑ribosylglycohydrolase family protein
RA 2,179,205 G→T 86.4% A24E (GCG→GAG)  rcnR ← transcriptional repressor of rcnA
RA 2,181,645 A→G 53.7% N83N (AAT→AAC yehA ← putative fimbrial‑like adhesin protein
RA 2,185,860 G→A 15.0% intergenic (‑159/+134) yehD ← / ← yehE putative fimbrial‑like adhesin protein/DUF2574 family protein
RA 2,194,695 T→A 93.3% L313Q (CTA→CAA)  yehI → DUF4132 domain‑containing protein
RA 2,195,449 A→T 100% E564D (GAA→GAT yehI → DUF4132 domain‑containing protein
RA 2,206,521 C→A 6.9% D535Y (GAT→TAT)  yehU ← inner membrane putative sensory kinase in two‑component system with YehT
RA 2,216,296 C→A 100% I211I (ATC→ATA dld → D‑lactate dehydrogenase, FAD‑binding, NADH independent
RA 2,222,684 G→C 7.5% intergenic (+140/+233) yohP → / ← dusC uncharacterized protein/tRNA‑dihydrouridine synthase C
RA 2,225,190 C→T 54.7% G231G (GGC→GGT yohK → LrgB family inner membrane protein
RA 2,237,098 G→T 88.0% H12N (CAT→AAT)  folE ← GTP cyclohydrolase I
RA 2,264,143 G→A 92.9% intergenic (+119/‑62) mepS → / → rtn murein DD‑endopeptidase, space‑maker hydrolase, mutational suppressor of prc thermosensitivity, outer membrane lipoprotein/resistance protein for phages lambda and N4, putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 2,289,374 C→A 94.3% V142V (GTG→GTT ccmC ← heme exporter subunit
RA 2,292,972 C→A 5.0% R29L (CGC→CTC)  napH ← ferredoxin‑type protein essential for electron transfer from ubiquinol to periplasmic nitrate reductase (NapAB)
RA 2,298,128 C→T 7.1% intergenic (+256/+459) eco → / ← mqo ecotin, a serine protease inhibitor/malate dehydrogenase, FAD/NAD(P)‑binding domain
RA 2,298,393 A→G 7.1% intergenic (+521/+194) eco → / ← mqo ecotin, a serine protease inhibitor/malate dehydrogenase, FAD/NAD(P)‑binding domain
RA 2,303,070 T→G 95.0% Q272P (CAG→CCG)  ada ← fused DNA‑binding transcriptional dual regulator/O6‑methylguanine‑DNA methyltransferase
RA 2,305,116 C→A 93.6% intergenic (‑103/+9) apbE ← / ← ompC putative thiamine‑synthetic flavin transferase lipoprotein/outer membrane porin protein C
RA 2,305,135 T→C 90.7% Y365C (TAC→TGC)  ompC ← outer membrane porin protein C
RA 2,306,584 T→A 15.2% noncoding (22/93 nt) micF → sRNA antisense regulator affecting ompF expression, Hfq‑dependent
RA 2,319,874 C→A 6.9% A96E (GCG→GAG)  atoB → acetyl‑CoA acetyltransferase
RA 2,330,502 C→A 41.7% D800Y (GAT→TAT)  gyrA ← DNA gyrase (type II topoisomerase), subunit A
RA 2,352,573 C→A 94.2% P353P (CCG→CCT rhmT ← putative L‑rhamnonate transporter
RA 2,352,965 C→A 11.9% E223* (GAA→TAA)  rhmT ← putative L‑rhamnonate transporter
RA 2,359,673 G→T 93.4% M89I (ATG→ATT arnB → uridine 5'‑(beta‑1‑threo‑pentapyranosyl‑4‑ulose diphosphate) aminotransferase, PLP‑dependent
RA 2,362,338 T→A 100% L274Q (CTG→CAG)  arnA → fused UDP‑L‑Ara4N formyltransferase/UDP‑GlcA C‑4'‑decarboxylase
RA 2,370,361:1 +G 100% coding (711/759 nt) menH ← 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase
RA 2,370,987 C→A 93.6% E29* (GAA→TAA)  menH ← 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase
RA 2,372,716 C→A 5.2% R8L (CGA→CTA)  menD ← 2‑succinyl‑5‑enolpyruvyl‑6‑hydroxy‑3‑ cyclohexene‑1‑carboxylate synthase; SEPHCHC synthase
RA 2,379,310 C→A 14.1% intergenic (‑109/‑29) yfbK ← / → yfbL Von Willebrand factor domain putative lipoprotein/putative peptidase
RA 2,381,180 G→A 11.4% intergenic (+264/+9) yfbM → / ← yfbN DUF1877 family protein/uncharacterized protein
RA 2,399,210 G→T 92.0% S304* (TCA→TAA)  lrhA ← transcriptional repressor of flagellar, motility and chemotaxis genes
RA 2,405,946 T→G 94.3% Q43P (CAG→CCG)  yfbU ← UPF0304 family protein
RA 2,416,101 C→A 90.3% intergenic (+21/+27) yfcH → / ← yfcI putative NAD‑dependent nucleotide‑sugar epimerase/transposase_31 family protein
RA 2,422,841 C→A 100% D293Y (GAT→TAT)  purF ← amidophosphoribosyltransferase
RA 2,424,074 C→T 93.7% D57N (GAC→AAC)  cvpA ← colicin V production membrane protein
RA 2,447,536 C→A 7.4% pseudogene (945/2646 nt) yfcU ← pseudogene, FimD fimbrial export usher family;putative membrane; Not classified; putative outer membrane protein
RA 2,450,335 C→T 93.2% intergenic (‑44/+159) sixA ← / ← fadJ phosphohistidine phosphatase/fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase
RA 2,450,346 G→T 91.9% intergenic (‑55/+148) sixA ← / ← fadJ phosphohistidine phosphatase/fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase
RA 2,451,874 T→A 7.7% E255D (GAA→GAT fadJ ← fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase
RA 2,452,454 G→T 89.8% P62Q (CCG→CAG)  fadJ ← fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase
RA 2,454,297 T→G 91.6% E39D (GAA→GAC yfcZ ← UPF0381 family protein
RA 2,457,708 G→T 23.0% intergenic (+159/+23) yfdF → / ← mlaA uncharacterized protein/ABC transporter maintaining OM lipid asymmetry, OM lipoprotein component
RA 2,463,906 C→A 16.9% Q433K (CAA→AAA)  gtrS → serotype‑specific glucosyl transferase, CPS‑53 (KpLE1) prophage
RA 2,463,915 C→A 8.9% Q436K (CAA→AAA)  gtrS → serotype‑specific glucosyl transferase, CPS‑53 (KpLE1) prophage
RA 2,466,589 T→G 6.3% pseudogene (476/708 nt) oweS ← pseudogene, CPS‑53 (KpLE1) prophage; bacteriophage replication protein O family;Phage or Prophage Related
RA 2,474,418 G→T 100% S413* (TCA→TAA)  emrY ← putative multidrug efflux system
RA 2,520,652 C→A 88.6% I116I (ATC→ATA yfeH → putative inorganic ion transporter
RA 2,525,538 G→T 7.6% A239A (GCG→GCT cysZ → EI24 family inner membrane protein; putative sulfate transporter
RA 2,549,676 C→A 91.4% L28L (CTG→CTT eutL ← putative ethanol utilization carboxysome structural protein
RA 2,568,720 C→T 93.9% A33T (GCC→ACC)  eutP ← putative P‑loop NTPase ethanolamine utilization protein
RA 2,570,299 C→A 5.7% E480* (GAA→TAA)  maeB ← malic enzyme: putative oxidoreductase/putative phosphotransacetylase
RA 2,576,325 C→A 94.3% E171D (GAG→GAT nudK ← GDP‑mannose pyrophosphatase
RA 2,580,597 C→A 7.4% T503K (ACG→AAG)  narQ → sensory histidine kinase in two‑component regulatory system with NarP (NarL)
RA 2,587,029:1 +G 94.0% coding (101/699 nt) ypfH ← palmitoyl‑CoA esterase activity, uncertain physiological substrate
RA 2,589,933 G→A 93.2% T55I (ACC→ATC)  ypfJ ← putative neutral zinc metallopeptidase
RA 2,602,418 C→A 8.8% I191I (ATC→ATA hyfG → hydrogenase 4, subunit
RA 2,606,516 G→T 100% D420Y (GAC→TAC)  hyfR → hydrogenase‑4 transcriptional activator
RA 2,610,919 C→A 87.6% intergenic (+3/‑18) bepA → / → yfgD periplasmic metalloprotease and chaperone for OM protein maintenance and assembly/putative oxidoreductase
RA 2,611,370 T→A 11.3% intergenic (+74/+64) yfgD → / ← hda putative oxidoreductase/ATPase regulatory factor involved in DnaA inactivation
RA 2,614,168 C→A 93.9% D22Y (GAT→TAT)  upp ← uracil phosphoribosyltransferase
RA 2,649,384 C→A 7.7% D112Y (GAC→TAC)  pepB ← aminopeptidase B
RA 2,651,665 G→T 100% G210G (GGC→GGA hscA ← DnaK‑like molecular chaperone specific for IscU
RA 2,664,779 G→T 8.5% D66Y (GAT→TAT)  hcaB → 2,3‑dihydroxy‑2,3‑dihydrophenylpropionate dehydrogenase
RA 2,665,754 T→G 8.4% L117V (TTG→GTG)  hcaD → phenylpropionate dioxygenase, ferredoxin reductase subunit
RA 2,671,274 C→A 94.0% T149T (ACG→ACT yphE ← putative sugar transporter subunit of ABC superfamily, ATP‑binding component
RA 2,681,873 T→A 100% Q97L (CAG→CTG)  glrR ← response regulator regulating glmY sRNA in two‑component system with sensor protein GlrK
RA 2,683,829 C→A 85.1% R210L (CGT→CTT)  glrK ← sensor protein kinase regulating glmY sRNA in two‑component system with response regulator GlrR
RA 2,685,077 T→A 5.3% N1276Y (AAC→TAC)  purL ← phosphoribosylformyl‑glycineamide synthetase
RA 2,689,722 T→G 13.2% L188* (TTA→TGA)  mltF → membrane‑bound lytic transglycosylase F, murein hydrolase
RA 2,702,530 G→T 7.6% A78A (GCC→GCA rseA ← anti‑sigma factor
RA 2,711,673 A→C 7.3% V72G (GTT→GGT)  yfiF ← putative methyltransferase
RA 2,715,643 G→T 92.3% E778* (GAA→TAA)  pka → protein lysine acetyltransferase
RA 2,719,426 T→C 100% intergenic (‑321/+2) kgtP ← / ← rrfG alpha‑ketoglutarate transporter/5S ribosomal RNA of rrnG operon
RA 2,726,786 C→A 91.1% A249A (GCG→GCT clpB ← protein disaggregation chaperone
RA 2,730,313 G→A 23.9% intergenic (+71/‑200) bamD → / → raiA BamABCDE complex OM biogenesis lipoprotein/cold shock protein associated with 30S ribosomal subunit
RA 2,733,753 C→T 100% E253K (GAG→AAG)  aroF ← 3‑deoxy‑D‑arabino‑heptulosonate‑7‑phosphate synthase, tyrosine‑repressible
RA 2,744,009 T→A 5.2% D20V (GAT→GTT)  grpE ← heat shock protein
RA 2,757,516 C→A 10.2% V333F (GTC→TTC)  yfjL ← CP4‑57 putative defective prophage, DUF4297/DUF1837 polymorphic toxin family protein
RA 2,771,358 G→A 92.2% intergenic (+217/+147) ypjF → / ← ypjA CP4‑57 prophage; toxin of the YpjF‑YfjZ toxin‑antitoxin system/adhesin‑like autotransporter
RA 2,779,067 C→A 93.2% intergenic (‑697/+54) ypjC ← / ← ileY pseudogene/tRNA‑Ile
RA 2,808,200 G→T 7.7% noncoding (40/78 nt) micA → sRNA antisense regulator of ompA, lamB, ompX, and phoP; Hfq‑dependent
RA 2,809,621 C→A 15.6% D60Y (GAT→TAT)  gshA ← glutamate‑cysteine ligase
RA 2,825,783 C→T 100% intergenic (‑135/‑52) norR ← / → norV anaerobic nitric oxide reductase DNA‑binding transcriptional activator/anaerobic nitric oxide reductase flavorubredoxin
RA 2,828,952 C→A 87.4% T611T (ACG→ACT hypF ← carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases
RA 2,841,044 C→A 60.6% A519A (GCG→GCT hycC ← hydrogenase 3, membrane subunit
RA 2,846,898 T→A 8.8% C96S (TGT→AGT)  hypE → carbamoyl dehydratase, hydrogenases 1,2,3 maturation protein
RA 2,850,790 C→A 92.6% I113I (ATC→ATA mutS → methyl‑directed mismatch repair protein
RA 2,873,087 G→T 100% V15V (GTC→GTA ygbT ← multifunctional endonuclease Cas1, CRISPR adaptation protein; DNA repair enzyme
RA 2,876,760 C→T 94.3% G246G (GGG→GGA casA ← CRISP RNA (crRNA) containing Cascade antiviral complex protein
RA 2,878,668 G→T 100% V637V (GTC→GTA ygcB ← R‑loop helicase‑annealase Cas3 needed for Cascade anti‑viral activity
RA 2,879,449 G→T 46.6% S377* (TCA→TAA)  ygcB ← R‑loop helicase‑annealase Cas3 needed for Cascade anti‑viral activity
RA 2,888,584 G→T 93.3% I185I (ATC→ATA ygcQ ← putative flavoprotein
RA 2,901,394 C→A 27.7% A544A (GCG→GCT pyrG ← CTP synthetase
RA 2,908,575 G→T 9.6% V54F (GTT→TTT)  barA → hybrid sensory histidine kinase, in two‑component regulatory system with UvrY
RA 2,921,151 C→T 8.7% intergenic (+120/‑437) ygdH → / → sdaC UPF0717 family protein/putative serine transporter
RA 2,931,717 C→A 100% N307K (AAC→AAA fucK → L‑fuculokinase
RA 2,934,843 G→T 94.8% H50N (CAT→AAT)  ygdD ← UPF0382 family inner membrane protein
RA 2,950,690 C→A 6.1% K518N (AAG→AAT ptrA ← protease III
RA 2,959,004 G→A 84.8% I131I (ATC→ATT lgt ← phosphatidylglycerol‑prolipoprotein diacylglyceryl transferase
RA 2,970,289 T→G 5.8% L111R (CTG→CGG)  galR → galactose‑inducible d‑galactose regulon transcriptional repressor; autorepressor
RA 2,985,221 G→A 5.4% intergenic (+103/‑232) ygeG → / → ygeH SycD‑like chaperone family TPR‑repeat‑containing protein/putative transcriptional regulator
RA 2,989,295 C→A 100% pseudogene (85/261 nt) ygeN ← pseudogene
RA 2,989,350 T→C 11.2% pseudogene (30/261 nt)
pseudogene (370/399 nt)
ygeN ←
ygeO ←
pseudogene
pseudogene, orgA homolog, part of T3SS PAI ETT2 remnant
RA 2,993,211 C→A 91.0% V14L (GTG→TTG)  ygeR ← LysM domain‑containing M23 family putative peptidase; septation lipoprotein
RA 2,993,699 C→A 88.9% intergenic (‑449/‑5) ygeR ← / → xdhA LysM domain‑containing M23 family putative peptidase; septation lipoprotein/xanthine dehydrogenase, molybdenum binding subunit
RA 3,017,285 G→T 82.1% D871Y (GAC→TAC)  xdhD → putative hypoxanthine oxidase, molybdopterin‑binding/Fe‑S binding
RA 3,024,983 C→G 90.4% G86G (GGC→GGG uacT → uric acid permease
RA 3,034,205 G→T 5.1% L75L (CTC→CTA sdhE ← flavinator of succinate dehydrogenase; antitoxin of CptAB toxin‑antitoxin pair
RA 3,039,409 T→G 15.8% intergenic (‑149/+118) ygfF ← / ← gcvP putative NAD(P)‑dependent oxidoreductase with NAD(P)‑binding Rossmann‑fold domain/glycine decarboxylase, PLP‑dependent, subunit (protein P) of glycine cleavage complex
RA 3,044,464 G→A 89.6% intergenic (‑438/+10) gcvT ← / ← ubiI aminomethyltransferase, tetrahydrofolate‑dependent, subunit (T protein) of glycine cleavage complex/2‑octaprenylphenol hydroxylase, FAD‑dependent
RA 3,051,973 C→T 14.6% intergenic (‑204/+52) serA ← / ← rpiA D‑3‑phosphoglycerate dehydrogenase/ribose 5‑phosphate isomerase, constitutive
RA 3,055,546 C→A 10.3% I446I (ATC→ATA scpA → methylmalonyl‑CoA mutase
RA 3,064,914 G→T 38.2% I356I (ATC→ATA pgk ← phosphoglycerate kinase
RA 3,075,114 C→A 100% intergenic (‑120/‑158) tktA ← / → loiP transketolase 1, thiamine triphosphate‑binding/Phe‑Phe periplasmic metalloprotease, OM lipoprotein; low salt‑inducible; heat shock protein that binds Era
RA 3,076,526 C→A 93.6% D211Y (GAC→TAC)  speB ← agmatinase
RA 3,080,618 T→A 100% V185E (GTG→GAG)  metK → S‑adenosylmethionine synthetase
RA 3,080,755 T→G 23.0% F231V (TTC→GTC)  metK → S‑adenosylmethionine synthetase
RA 3,080,759 T→G 7.0% V232G (GTT→GGT)  metK → S‑adenosylmethionine synthetase
RA 3,110,751 C→A 90.1% R574L (CGT→CTT)  yghJ ← DUF4092 family putative lipoprotein peptidase
RA 3,111,434 C→A 91.6% A346A (GCG→GCT yghJ ← DUF4092 family putative lipoprotein peptidase
RA 3,116,290 C→G 8.1% G292A (GGC→GCC)  glcB ← malate synthase G
RA 3,120,216 C→A 100% D389Y (GAT→TAT)  glcD ← glycolate oxidase subunit, FAD‑linked
RA 3,144,158 C→A 55.3% intergenic (+253/+19) yghA → / ← exbD putative oxidoreductase/membrane spanning protein in TonB‑ExbB‑ExbD complex
RA 3,167,181 C→A 10.0% P525P (CCG→CCT parE ← DNA topoisomerase IV, subunit B
RA 3,173,669 G→T 90.4% A189A (GCG→GCT ygiB → DUF1190 family protein
RA 3,212,034 G→T 9.3% N134K (AAC→AAA aer ← fused signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component
RA 3,224,927 C→A 88.7% intergenic (+329/‑97) ygjK → / → fadH alpha‑glucosidase/2,4‑dienoyl‑CoA reductase, NADH and FMN‑linked
RA 3,225,516 G→T 7.2% E165* (GAA→TAA)  fadH → 2,4‑dienoyl‑CoA reductase, NADH and FMN‑linked
RA 3,245,848 G→T 84.8% L62L (CTG→CTT yhaH → DUF805 family inner membrane protein
RA 3,247,576 C→T 9.3% intergenic (‑3/‑102) yhaJ ← / → yhaK LysR family putative transcriptional regulator/redox‑sensitive bicupin
RA 3,252,258 C→A 92.9% D251Y (GAT→TAT)  tdcG ← L‑serine dehydratase 3, anaerobic
RA 3,263,502 C→T 5.0% intergenic (+541/+73) yhaC → / ← rnpB pentapetide repeats‑related protein/RNase P, M1 RNA component
RA 3,266,646 C→A 53.9% G91C (GGT→TGT)  garL ← alpha‑dehydro‑beta‑deoxy‑D‑glucarate aldolase
RA 3,302,027 G→T 94.6% S86* (TCG→TAG)  nlpI ← lipoprotein involved in osmotic sensitivity and filamentation
RA 3,311,918 C→T 12.7% intergenic (‑270/‑78) metY ← / → argG tRNA‑Met/argininosuccinate synthetase
RA 3,314,870 C→A 62.7% A35S (GCG→TCG)  yhbX ← putative EptAB family phosphoethanolamine transferase, inner membrane protein
RA 3,324,218 G→T 6.2% A299E (GCG→GAG)  obgE ← GTPase involved in cell partioning and DNA repair
RA 3,326,092 C→A 7.4% M1M (ATG→ATT) † yhbE ← EamA family inner membrane putative transporter
RA 3,347,778 G→A 92.2% intergenic (‑369/‑306) yhcC ← / → gltB putative Fe‑S oxidoreductase, Radical SAM superfamily protein/glutamate synthase, large subunit
RA 3,354,405 C→T 94.4% intergenic (+430/‑130) gltD → / → gltF glutamate synthase, 4Fe‑4S protein, small subunit/periplasmic protein
RA 3,365,607 G→T 91.5% I109I (ATC→ATA nanT ← sialic acid transporter
RA 3,366,537 C→A 16.0% P133P (CCG→CCT nanA ← N‑acetylneuraminate lyase
RA 3,373,985 C→A 100% intergenic (+37/‑117) yhcB → / → degQ DUF1043 family inner membrane‑anchored protein/serine endoprotease, periplasmic
RA 3,375,260 G→T 100% D387Y (GAT→TAT)  degQ → serine endoprotease, periplasmic
RA 3,385,487 A→T 5.5% intergenic (‑100/+330) tldD ← / ← yhdP putative peptidase/DUF3971‑AsmA2 domains protein
RA 3,385,516 A→T 7.1% intergenic (‑129/+301) tldD ← / ← yhdP putative peptidase/DUF3971‑AsmA2 domains protein
RA 3,396,082 G→T 100% R204S (CGT→AGT)  csrD ← targeting factor for csrBC sRNA degradation
RA 3,396,554 C→A 6.6% A46A (GCG→GCT csrD ← targeting factor for csrBC sRNA degradation
RA 3,409,403 C→A 16.0% H338N (CAC→AAC)  acrF → multidrug efflux system protein
RA 3,411,456 C→A 10.5% P1022Q (CCG→CAG)  acrF → multidrug efflux system protein
RA 3,439,422 G→T 11.0% I26I (ATC→ATA rplF ← 50S ribosomal subunit protein L6
RA 3,439,443 G→T 11.9% I19I (ATC→ATA rplF ← 50S ribosomal subunit protein L6
RA 3,440,151 G→T 89.7% I31I (ATC→ATA rpsN ← 30S ribosomal subunit protein S14
RA 3,440,444 G→T 100% S118S (TCC→TCA rplE ← 50S ribosomal subunit protein L5
RA 3,440,832 T→C 54.7% N99D (AAC→GAC)  rplX ← 50S ribosomal subunit protein L24
RA 3,441,606 G→T 15.3% intergenic (‑98/+67) rplN ← / ← rpsQ 50S ribosomal subunit protein L14/30S ribosomal subunit protein S17
RA 3,455,867 C→A 92.7% I55I (ATC→ATA gspJ → putative general secretory pathway component, cryptic
RA 3,469,906 T→A 7.0% intergenic (‑107/+60) yheO ← / ← fkpA putative PAS domain‑containing DNA‑binding transcriptional regulator/FKBP‑type peptidyl‑prolyl cis‑trans isomerase (rotamase)
RA 3,473,139 G→T 100% I276I (ATC→ATA kefB ← potassium:proton antiporter
RA 3,476,264 C→A 6.0% S539R (AGC→AGA yheS → putative transporter subunit of ABC superfamily: ATP‑binding component
RA 3,479,537 A→T 7.4% H20L (CAC→CTC)  crp → cAMP‑activated global transcription factor, mediator of catabolite repression
RA 3,479,542 C→A 12.5% H22N (CAT→AAT)  crp → cAMP‑activated global transcription factor, mediator of catabolite repression
RA 3,479,769 A→T 65.2% E97D (GAA→GAT crp → cAMP‑activated global transcription factor, mediator of catabolite repression
RA 3,488,966 G→C 62.0% A533P (GCC→CCC)  nirB → nitrite reductase, large subunit, NAD(P)H‑binding
RA 3,489,397 C→A 42.0% F676L (TTC→TTA nirB → nitrite reductase, large subunit, NAD(P)H‑binding
RA 3,501,571 C→A 48.1% G127C (GGC→TGC)  php ← phosphotriesterase homology protein
RA 3,504,362 A→G 7.1% intergenic (‑27/+57) yhfX ← / ← yhfY putative pyridoxal 5'‑phosphate binding protein/PRD domain protein
RA 3,507,749 G→T 47.6% H224N (CAT→AAT)  rpe ← D‑ribulose‑5‑phosphate 3‑epimerase
RA 3,519,657 G→T 100% intergenic (‑149/‑171) nudE ← / → yrfF adenosine nucleotide hydrolase; substrates include Ap3A, Ap2A, ADP‑ribose, NADH/inner membrane protein
RA 3,520,764 G→T 7.3% D313Y (GAC→TAC)  yrfF → inner membrane protein
RA 3,520,789 G→T 9.3% R321L (CGA→CTA)  yrfF → inner membrane protein
RA 3,522,558 G→T 5.1% A177A (GCG→GCT yrfG → GMP/IMP nucleotidase
RA 3,525,232 T→A 10.4% L189F (TTA→TTT yhgE ← DUF4153 family putative inner membrane protein
RA 3,525,943 G→A 11.1% intergenic (‑145/‑234) yhgE ← / → pck DUF4153 family putative inner membrane protein/phosphoenolpyruvate carboxykinase
RA 3,543,959 G→T 100% A625E (GCG→GAG)  malP ← maltodextrin phosphorylase
RA 3,559,196 T→G 10.9% Q249P (CAG→CCG)  glgP ← glycogen phosphorylase
RA 3,559,239 T→A 8.7% S235C (AGT→TGT)  glgP ← glycogen phosphorylase
RA 3,561,574 C→A 100% W372L (TGG→TTG)  glgC ← glucose‑1‑phosphate adenylyltransferase
RA 3,595,522 C→A 18.6% D196Y (GAC→TAC)  ftsE ← putative ABC superfamily transporter ATP‑binding subunit
RA 3,602,383 C→A 16.6% intergenic (‑27/‑194) tusA ← / → yhhQ mnm(5)‑s(2)U34‑tRNA 2‑thiolation sulfurtransferase/DUF165 family inner membrane protein
RA 3,617,026 A→G 11.0% T90A (ACA→GCA)  yhhH → putative immunity protein for putative polymorphic toxin RhsB
RA 3,629,436 T→A 5.7% intergenic (+183/+132) yhiM → / ← yhiN acid resistance protein, inner membrane/putative oxidoreductase
RA 3,630,907 G→A 5.2% intergenic (‑137/‑95) yhiN ← / → pitA putative oxidoreductase/phosphate transporter, low‑affinity; tellurite importer
RA 3,632,965 A→G 8.6% L39S (TTG→TCG)  uspB ← universal stress (ethanol tolerance) protein B
RA 3,641,809 A→G 5.4% intergenic (+72/‑79) agrB → / → arsR Antisense sRNA antitoxin for the DinQ toxin/arsenical resistance operon transcriptional repressor; autorepressor
RA 3,654,444 A→T 5.0% Q224L (CAG→CTG)  mdtF → anaerobic multidrug efflux transporter, ArcA‑regulated
RA 3,662,660 T→C 64.3% intergenic (‑112/‑292) yhjA ← / → treF putative cytochrome C peroxidase/cytoplasmic trehalase
RA 3,679,301 T→G 93.0% Q1078P (CAG→CCG)  bcsC ← cellulose synthase subunit
RA 3,679,324 C→A 93.8% M1070I (ATG→ATT bcsC ← cellulose synthase subunit
RA 3,680,910 G→T 57.6% H542N (CAT→AAT)  bcsC ← cellulose synthase subunit
RA 3,682,184 T→G 9.9% Q117P (CAA→CCA)  bcsC ← cellulose synthase subunit
RA 3,696,812 C→A 6.7% D133Y (GAC→TAC)  dppD ← dipeptide/heme transporter
RA 3,717,788 C→A 93.4% P297P (CCG→CCT glyQ ← glycine tRNA synthetase, alpha subunit
RA 3,721,469 A→C 8.3% D421E (GAT→GAG xylB ← xylulokinase
RA 3,721,480 T→G 9.2% T418P (ACG→CCG)  xylB ← xylulokinase
RA 3,738,431 C→A 92.2% P90T (CCA→ACA)  yiaN → 2,3‑diketo‑L‑gulonate TRAP transporter large permease protein
RA 3,744,506 C→A 7.8% G241G (GGG→GGT yiaT ← putative outer membrane protein
RA 3,774,382 T→G 13.9% intergenic (+5/‑193) lldD → / → trmL L‑lactate dehydrogenase, FMN‑linked/tRNA Leu mC34,mU34 2'‑O‑methyltransferase, SAM‑dependent
RA 3,779,281 C→G 7.2% A221G (GCT→GGT)  gpmM → phosphoglycero mutase III, cofactor‑independent
RA 3,779,319 G→T 12.3% E234* (GAA→TAA)  gpmM → phosphoglycero mutase III, cofactor‑independent
RA 3,785,915 G→T 100% intergenic (‑4/+271) kbl ← / ← yibB glycine C‑acetyltransferase/YibB family protein, function unknown
RA 3,801,112 C→T 11.0% S116N (AGC→AAC)  waaQ ← lipopolysaccharide core biosynthesis protein
RA 3,810,195 C→A 100% R54S (CGT→AGT)  yicC → UPF0701 family protein
RA 3,816,601 A→T 100% H281L (CAC→CTC)  spoT → bifunctional (p)ppGpp synthetase II/ guanosine‑3',5'‑bis pyrophosphate 3'‑pyrophosphohydrolase
RA 3,818,010 C→A 100% H46N (CAT→AAT)  trmH → tRNA mG18‑2'‑O‑methyltransferase, SAM‑dependent
RA 3,822,339 A→C 14.4% Q12P (CAA→CCA) ‡ xanP → xanthine permease
RA 3,822,340 A→C 8.6% Q12H (CAA→CAC) ‡ xanP → xanthine permease
RA 3,825,702 C→A 94.9% K732N (AAG→AAT yicI ← putative alpha‑glucosidase
RA 3,830,197 C→A 94.3% intergenic (+281/‑116) yicT → / → setC pseudogene/putative arabinose efflux transporter
RA 3,830,311 G→T 93.4% intergenic (+395/‑2) yicT → / → setC pseudogene/putative arabinose efflux transporter
RA 3,832,001 G→T 10.1% A132S (GCT→TCT)  yicL → EamA family inner membrane putative transporter
RA 3,849,854 A→T 7.7% H27L (CAC→CTC)  yidI → inner membrane protein
RA 3,860,159 C→A 100% P33P (CCG→CCT ibpB ← heat shock chaperone
RA 3,870,977 T→A 8.0% intergenic (‑152/+88) yidB ← / ← gyrB DUF937 family protein/DNA gyrase, subunit B
RA 3,904,487 G→T 21.7% I133I (ATC→ATA pstS ← periplasmic phosphate binding protein, high‑affinity
RA 3,907,456 C→A 9.9% D369Y (GAT→TAT)  glmU ← fused N‑acetyl glucosamine‑1‑phosphate uridyltransferase/glucosamine‑1‑phosphate acetyl transferase
RA 3,907,559 A→T 19.5% P334P (CCT→CCA glmU ← fused N‑acetyl glucosamine‑1‑phosphate uridyltransferase/glucosamine‑1‑phosphate acetyl transferase
RA 3,910,894 C→A 100% M244I (ATG→ATT atpG ← F1 sector of membrane‑bound ATP synthase, gamma subunit
RA 3,911,608 C→A 7.0% E6D (GAG→GAT atpG ← F1 sector of membrane‑bound ATP synthase, gamma subunit
RA 3,916,830 C→A 91.0% D71Y (GAT→TAT)  rsmG ← 16S rRNA m(7)G527 methyltransferase, SAM‑dependent; glucose‑inhibited cell‑division protein
RA 3,917,233 G→T 10.1% I587I (ATC→ATA mnmG ← 5‑methylaminomethyl‑2‑thiouridine modification at tRNA U34
RA 3,921,982 T→A 10.8% T328S (ACT→TCT)  viaA ← stimulator of RavA ATPase activity; von Willebrand factor domain protein
RA 3,926,496 A→C 5.4% E607D (GAA→GAC kup → potassium transporter
RA 3,926,831 G→T 46.4% D41Y (GAT→TAT)  rbsD → putative cytoplasmic sugar‑binding protein
RA 3,927,123 C→A 8.7% T138K (ACG→AAG)  rbsD → putative cytoplasmic sugar‑binding protein
RA 3,930,339 G→T 6.4% V234V (GTG→GTT rbsB → D‑ribose transporter subunit
RA 3,932,727 C→A 17.2% V416F (GTT→TTT)  hsrA ← putative multidrug or homocysteine efflux system
RA 3,933,988 C→A 6.8% intergenic (‑16/+7) hsrA ← / ← yieP putative multidrug or homocysteine efflux system/putative transcriptional regulator
RA 3,944,267 A→T 11.2% pseudogene (348/984 nt) ilvG → pseudogene, acetolactate synthase 2 large subunit, valine‑insensitive; acetolactate synthase II, large subunit, cryptic, interrupted
RA 3,944,734 G→T 9.9% pseudogene (815/984 nt) ilvG → pseudogene, acetolactate synthase 2 large subunit, valine‑insensitive; acetolactate synthase II, large subunit, cryptic, interrupted
RA 3,951,770 C→A 10.6% I147I (ATC→ATA ilvC → ketol‑acid reductoisomerase, NAD(P)‑binding
RA 3,960,036 G→A 100% R87H (CGC→CAC)  rho → transcription termination factor
RA 3,966,854 C→A 61.0% R325S (CGT→AGT)  rffG → dTDP‑glucose 4,6‑dehydratase
RA 3,969,710 G→T 45.6% G25C (GGT→TGT)  wzxE → O‑antigen translocase
RA 3,971,254 C→T 5.6% L124F (CTT→TTT)  wecF → TDP‑Fuc4NAc:lipidIIFuc4NAc transferase
RA 3,988,075 T→A 62.6% V65E (GTG→GAG)  yifL → putative lipoprotein
RA 3,994,076 A→T 100% L114* (TTA→TAA)  yigE ← DUF2233 family protein
RA 3,994,247 A→T 100% V57E (GTG→GAG)  yigE ← DUF2233 family protein
RA 4,009,705 G→A 100% intergenic (‑176/‑86) ysgA ← / → udp putative carboxymethylenebutenolidase/uridine phosphorylase
RA 4,056,018 T→A 94.2% F138I (TTC→ATC)  yihN → MFS transporter family protein
RA 4,062,424 G→T 93.3% I71I (ATC→ATA yihQ ← alpha‑glucosidase
RA 4,066,133 T→G 94.9% S267R (AGC→CGC)  yihU ← gamma‑hydroxybutyrate dehydrogenase, NADH‑dependent
RA 4,068,208 C→A 93.9% G60G (GGC→GGA yihW → DeoR family putative transcriptional regulator
RA 4,085,145 A→C 5.9% A194A (GCT→GCG frvB ← putative PTS enzyme, IIB component/IIC component
RA 4,085,600 G→T 12.0% Q43K (CAA→AAA)  frvB ← putative PTS enzyme, IIB component/IIC component
RA 4,094,362 C→A 100% W181L (TGG→TTG)  cpxA ← sensory histidine kinase in two‑component regulatory system with CpxR
RA 4,097,822 G→T 92.3% E115* (GAA→TAA)  pfkA → 6‑phosphofructokinase I
RA 4,127,022 T→G 100% E188D (GAA→GAC yijF ← DUF1287 family protein
RA 4,143,375 A→G 5.3% intergenic (‑349/+249) ppc ← / ← argE phosphoenolpyruvate carboxylase/acetylornithine deacetylase
RA 4,172,714 T→A 6.8% F514L (TTT→TTA rpoB → RNA polymerase, beta subunit
RA 4,176,823 G→T 92.9% D516Y (GAC→TAC)  rpoC → RNA polymerase, beta prime subunit
RA 4,177,037 T→A 9.2% L587Q (CTG→CAG)  rpoC → RNA polymerase, beta prime subunit
RA 4,177,592 A→T 6.5% Y772F (TAC→TTC)  rpoC → RNA polymerase, beta prime subunit
RA 4,187,518 G→T 13.4% D230Y (GAT→TAT)  nudC → NADH pyrophosphatase
RA 4,211,576 G→T 94.0% S280R (AGC→AGA arpA ← ankyrin repeat protein
RA 4,211,803 G→A 93.3% P205S (CCT→TCT)  arpA ← ankyrin repeat protein
RA 4,212,560 G→T 8.0% intergenic (‑145/+172) arpA ← / ← iclR ankyrin repeat protein/transcriptional repressor
RA 4,218,688 G→T 7.8% D344Y (GAC→TAC)  yjbB → putative Na+/Pi‑cotransporter
RA 4,226,640 G→T 9.1% D151Y (GAT→TAT)  yjbF → extracellular polysaccharide production lipoprotein
RA 4,230,913 A→T 100% W424R (TGG→AGG)  xylE ← D‑xylose transporter
RA 4,241,411 A→G 8.7% pseudogene (523/1323 nt) yjbI → pseudogene, SopA‑related, pentapeptide repeats‑containing
RA 4,242,023 G→T 11.2% pseudogene (1135/1323 nt) yjbI → pseudogene, SopA‑related, pentapeptide repeats‑containing
RA 4,250,324 G→A 19.7% A26T (GCA→ACA)  yjbL → uncharacterized protein
RA 4,265,064 C→A 61.9% intergenic (‑95/‑335) yjcB ← / → yjcC putative inner membrane protein/putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 4,274,926 A→C 94.1% I72M (ATT→ATG yjcH ← DUF485 family inner membrane protein
RA 4,280,688 G→T 7.1% S95S (TCG→TCT nrfD → formate‑dependent nitrite reductase, membrane subunit
RA 4,285,892 A→G 7.9% intergenic (+170/+361) gltP → / ← yjcO glutamate/aspartate:proton symporter/Sel1 family TPR‑like repeat protein
RA 4,285,893 A→C 8.7% intergenic (+171/+360) gltP → / ← yjcO glutamate/aspartate:proton symporter/Sel1 family TPR‑like repeat protein
RA 4,286,118 A→G 7.6% intergenic (+396/+135) gltP → / ← yjcO glutamate/aspartate:proton symporter/Sel1 family TPR‑like repeat protein
RA 4,286,119 A→C 7.5% intergenic (+397/+134) gltP → / ← yjcO glutamate/aspartate:proton symporter/Sel1 family TPR‑like repeat protein
RA 4,290,080 G→T 93.3% I256I (ATC→ATA mdtP ← outer membrane factor of efflux pump
RA 4,297,846 C→A 100% M150I (ATG→ATT alsE ← allulose‑6‑phosphate 3‑epimerase
RA 4,300,732 C→T 6.4% K22K (AAG→AAA alsA ← fused D‑allose transporter subunits of ABC superfamily: ATP‑binding components
RA 4,303,614 T→A 100% *150R (TGA→AGA)  rpiB → ribose 5‑phosphate isomerase B/allose 6‑phosphate isomerase
RA 4,312,726 G→T 11.9% pseudogene (322/426 nt) phnE ← defective phosphonate ABC transporter permease;transport; Transport of small molecules: Anions; membrane channel protein component of Pn transporter; membrane component of ABC superfamily
RA 4,315,765 A→G 6.0% intergenic (‑207/+451) yjdN ← / ← yjdM metalloprotein superfamily protein/zinc‑ribbon family protein
RA 4,330,426 Δ1 bp 100% intergenic (‑88/+111) adiA ← / ← melR arginine decarboxylase/melibiose operon transcriptional regulator; autoregulator
RA 4,341,023 A→T 49.3% Y153N (TAC→AAC)  dcuS ← sensory histidine kinase in two‑component regulatory system with DcuR, regulator of anaerobic fumarate respiration
RA 4,341,110 C→A 10.5% D124Y (GAC→TAC)  dcuS ← sensory histidine kinase in two‑component regulatory system with DcuR, regulator of anaerobic fumarate respiration
RA 4,356,174 A→T 10.9% I139I (ATT→ATA dcuA ← C4‑dicarboxylate antiporter
RA 4,361,651 C→A 6.9% I270I (ATC→ATA groL → Cpn60 chaperonin GroEL, large subunit of GroESL
RA 4,375,503 T→A 6.4% I98I (ATT→ATA yjeN → uncharacterized protein
RA 4,376,532 C→T 5.6% G886R (GGG→AGG)  mscM ← mechanosensitive channel protein, miniconductance
RA 4,388,902 G→T 100% A558A (GCG→GCT mutL → methyl‑directed mismatch repair protein
RA 4,396,598 A→T 100% E43V (GAA→GTA)  rnr → exoribonuclease R, RNase R
RA 4,411,145 T→G 8.6% L450R (CTG→CGG)  ulaA → L‑ascorbate‑specific enzyme IIC permease component of PTS
RA 4,417,551 A→C 66.6% pseudogene (41/402 nt) ytfA → pseudogene, related to transcriptional regulators
RA 4,432,682 G→T 9.0% E162* (GAA→TAA)  tamA → translocation and assembly module for autotransporter export, outer membrane subunit
RA 4,433,194 C→A 7.9% G332G (GGC→GGA tamA → translocation and assembly module for autotransporter export, outer membrane subunit
RA 4,458,254 T→A 100% V271V (GTT→GTA mgtA → magnesium transporter
RA 4,458,609 G→T 100% D390Y (GAT→TAT)  mgtA → magnesium transporter
RA 4,466,283 A→T 5.7% N344Y (AAC→TAC)  yjgL → uncharacterized protein
RA 4,468,165 A→G 83.6% intergenic (‑37/‑125) argI ← / → rraB ornithine carbamoyltransferase 1/protein inhibitor of RNase E
RA 4,468,750 G→T 8.6% intergenic (+44/+101) rraB → / ← yjgM protein inhibitor of RNase E/putative acetyltransferase
RA 4,469,550 G→A 94.6% A2T (GCT→ACT)  yjgN → DUF898 family inner membrane protein
RA 4,470,017 G→A 100% M157I (ATG→ATA yjgN → DUF898 family inner membrane protein
RA 4,497,208 C→A 19.6% pseudogene (195/255 nt) insO → pseudogene, IS911 transposase B;IS, phage, Tn; Transposon‑related functions; extrachromosomal; transposon related
RA 4,500,728 C→A 6.5% E183* (GAA→TAA)  fecE ← iron‑dicitrate transporter subunit
RA 4,506,430 A→T 8.3% L22Q (CTG→CAG)  fecA ← ferric citrate outer membrane transporter
RA 4,506,776 C→A 5.3% P253P (CCG→CCT fecR ← FecI pro‑sigma factor; transmembrane signal transducer for ferric citrate transport; periplasmic FecA:ferric citrate sensor and cytoplasmic FecI ECF sigma factor activator
RA 4,510,428 G→T 5.2% intergenic (‑287/+60) yjhU ← / ← yjhF putative DNA‑binding transcriptional regulator; KpLE2 phage‑like element/putative transporter
RA 4,512,693 T→A 100% K407* (AAG→TAG)  yjhG ← putative dehydratase
RA 4,515,264 C→A 12.7% P119P (CCG→CCT yjhI ← putative DNA‑binding transcriptional regulator
RA 4,516,734 G→T 17.3% F207L (TTC→TTA sgcE ← putative epimerase
RA 4,525,234 G→A 92.9% pseudogene (415/1029 nt) yjhR → pseudogene, helicase family; putative frameshift suppressor
RA 4,527,381 A→T 8.4% Y11N (TAT→AAT)  nanS ← 9‑O‑acetyl N‑acetylneuraminic acid esterase
RA 4,529,829 T→C 11.2% intergenic (‑511/‑945) nanC ← / → fimB N‑acetylnuraminic acid outer membrane channel protein/tyrosine recombinase/inversion of on/off regulator of fimA
RA 4,531,143 A→T 100% I124F (ATT→TTT)  fimB → tyrosine recombinase/inversion of on/off regulator of fimA
RA 4,555,156 G→T 55.5% A171E (GCG→GAG)  yjiM ← putative 2‑hydroxyglutaryl‑CoA dehydratase
RA 4,556,947 G→C 7.8% G39G (GGC→GGG yjiN ← zinc‑type alcohol dehydrogenase‑like protein
RA 4,562,043 C→A 100% intergenic (+311/‑188) yjiS → / → yjiT DUF1127 family protein/pseudogene
RA 4,562,157 C→T 6.1% intergenic (+425/‑74) yjiS → / → yjiT DUF1127 family protein/pseudogene
RA 4,571,551 C→A 12.3% D439Y (GAC→TAC)  hsdM ← DNA methyltransferase M
RA 4,577,795 C→A 6.1% T296T (ACG→ACT yjiA ← GTP‑binding protein, putative GTPase
RA 4,584,381 G→T 100% I53I (ATC→ATA yjjL ← L‑galactonate transporter
RA 4,585,338 A→T 54.3% S111T (TCT→ACT)  yjjM ← yjjMN operon transcriptional activator
RA 4,596,127 G→T 5.7% intergenic (‑24/+5) leuP ← / ← leuQ tRNA‑Leu/tRNA‑Leu
RA 4,600,859 A→T 10.2% intergenic (+39/‑354) prfC → / → osmY peptide chain release factor RF‑3/periplasmic protein
RA 4,604,195 A→G 5.3% intergenic (+118/+302) yjjV → / ← yjjW putative DNase/putative pyruvate formate lyase activating enzyme
RA 4,604,261 A→G 6.1% intergenic (+184/+236) yjjV → / ← yjjW putative DNase/putative pyruvate formate lyase activating enzyme
RA 4,605,290 A→T 5.8% L24Q (CTG→CAG)  yjjW ← putative pyruvate formate lyase activating enzyme
RA 4,619,126 C→A 6.4% W405L (TGG→TTG)  yjjK ← putative transporter subunit of ABC superfamily: ATP‑binding component
RA 4,625,288 T→C 47.6% intergenic (‑161/‑50) rob ← / → creA right oriC‑binding transcriptional activator, AraC family/putative periplasmic protein

Unassigned missing coverage evidence
   seq id start end size ←reads reads→ gene description
* * ÷ CP009273 373899 375070 1172 111 [109] [109] 110 frmA–[frmR] frmA,[frmR]
* * ÷ CP009273 4100634 4101474 841 112 [109] [107] 114 tpiA tpiA

Unassigned new junction evidence
  seq id position reads (cov) reads (cov) score skew freq annotation gene product
* ? CP009273 360104 =244 (0.910)189 (0.710) 111/278 NT 43.6% intergenic (‑38/+557) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 360286 NA (NA)intergenic (‑220/+375) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
* ? CP009273 = 360278NA (NA)7221 (28.610)
+TTAATTAA
195/262 NT 96.6% intergenic (‑212/+383) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 361823 268 (1.000)coding (831/834 nt) mhpR mhp operon transcriptional activator
* ? CP009273 360652 =389 (1.450)7150 (40.020)
+46 bp
186/186 NT 97.1% intergenic (‑586/+9) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 1317577 256 (0.960)coding (101/882 nt) yciV PHP domain protein
* ? CP009273 376716 =NA (NA)215 (0.800) 123/278 NT 99.5% intergenic (‑1/‑91) yaiX/insC1 pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase/IS2 repressor TnpA
?CP009273 566411 = 1 (0.000)coding (63/552 nt) ybcL inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family
* ? CP009273 = 378046NA (NA)200 (0.750) 104/278 NT 99.5% intergenic (+11/+1) insD1/yaiX IS2 transposase TnpB/pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase
?CP009273 = 566415 1 (0.000)coding (67/552 nt) ybcL inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family
* ? CP009273 1203246 =23 (0.090)168 (0.710) 95/246 NT 91.0% coding (290/630 nt) stfP e14 prophage; uncharacterized protein
?CP009273 1205075 = 13 (0.050)pseudogene (1/501 nt) stfE pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
* ? CP009273 = 120326122 (0.080)263 (1.110) 122/246 NT 94.2% coding (305/630 nt) stfP e14 prophage; uncharacterized protein
?CP009273 = 1205058 13 (0.050)pseudogene (18/501 nt) stfE pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
* ? CP009273 1635219 =4 (0.020)186 (0.700) 106/274 NT 97.9% intergenic (‑377/+377) essQ/cspB Qin prophage; putative S lysis protein/Qin prophage; cold shock protein
?CP009273 = 2063752 NA (NA)noncoding (1/1331 nt) IS2 repeat region
* ? CP009273 = 16352238 (0.030)198 (0.740) 113/278 NT 96.1% intergenic (‑381/+373) essQ/cspB Qin prophage; putative S lysis protein/Qin prophage; cold shock protein
?CP009273 = 1645805 NA (NA)intergenic (+11/‑3) insD1/intQ IS2 transposase TnpB;IS, phage, Tn; Transposon‑related functions; extrachromosomal; transposon related/pseudogene, Qin prophage; phage integrase family;Phage or Prophage Related
* ? CP009273 = 2164908NA (NA)7 (0.030) 6/276 NT 7.0% intergenic (+29/+2) insF1/gatR IS3 transposase B/pseudogene, repressor for gat operon; interrupted by IS3; split galactitol utilization operon repressor, fragment 2; split galactitol utilization operon repressor, interrupted
?CP009273 3763272 = 94 (0.350)intergenic (+129/‑36) yibV/yibU pseudogene/pseudogene, H repeat‑associated protein