breseq  version 0.35.4  revision f352f80f4bc9
mutation predictions | marginal predictions | summary statistics | genome diff | command line log

Predicted mutations
evidence position mutation freq annotation gene description
RA 558 T→A 9.1% L74L (CTT→CTA thrA → Bifunctional aspartokinase/homoserine dehydrogenase 1
RA 5,144 G→A 50.3% intergenic (+124/‑90) thrC → / → yaaX L‑threonine synthase/DUF2502 family putative periplasmic protein
RA 7,905 A→C 17.4% Y19D (TAC→GAC)  yaaJ ← putative transporter
RA 8,137 G→T 6.7% intergenic (‑178/‑101) yaaJ ← / → talB putative transporter/transaldolase B
RA 10,444 G→T 72.6% F17L (TTC→TTA satP ← succinate‑acetate transporter
RA 13,218 A→C 5.9% K352N (AAA→AAC dnaK → chaperone Hsp70, with co‑chaperone DnaJ
RA 13,327 G→T 5.9% V389L (GTA→TTA)  dnaK → chaperone Hsp70, with co‑chaperone DnaJ
RA 29,139 G→T 41.3% G256C (GGT→TGT)  dapB → dihydrodipicolinate reductase
RA 30,176 A→T 8.3% T176S (ACG→TCG)  carA → carbamoyl phosphate synthetase small subunit, glutamine amidotransferase
RA 34,496 T→A 7.5% L66Q (CTG→CAG)  caiF → cai operon transcriptional activator
RA 39,866 G→T 6.2% S174Y (TCT→TAT)  caiA ← crotonobetaine reductase subunit II, FAD‑binding
RA 43,364 G→T 12.1% P59P (CCG→CCT fixB → putative electron transfer flavoprotein, NAD/FAD‑binding domain and ETFP adenine nucleotide‑binding domain‑like protein
RA 43,550 G→A 5.9% A121A (GCG→GCA fixB → putative electron transfer flavoprotein, NAD/FAD‑binding domain and ETFP adenine nucleotide‑binding domain‑like protein
RA 56,677 G→T 47.5% R145S (CGC→AGC)  lptD ← LPS assembly OM complex LptDE, beta‑barrel component
RA 57,529 G→T 6.6% A56S (GCC→TCC)  djlA → membrane‑anchored DnaK co‑chaperone, DNA‑binding protein
RA 72,337 C→A 9.6% D484Y (GAC→TAC)  sgrR ← transcriptional DNA‑binding transcriptional activator of sgrS sRNA
RA 72,392 G→T 26.9% F465L (TTC→TTA sgrR ← transcriptional DNA‑binding transcriptional activator of sgrS sRNA
RA 88,442 T→A 6.9% F181L (TTT→TTA ftsI → transpeptidase involved in septal peptidoglycan synthesis (penicillin‑binding protein 3)
RA 104,948 A→T 42.7% E61D (GAA→GAT secA → preprotein translocase subunit, ATPase
RA 105,563 C→A 12.5% D266E (GAC→GAA secA → preprotein translocase subunit, ATPase
RA 116,066 G→T 5.4% R100L (CGT→CTT)  ampE → ampicillin resistance inner membrane protein; putative signaling protein in beta‑lactamase regulation
RA 118,828 G→T 15.4% D84Y (GAT→TAT)  pdhR → pyruvate dehydrogenase complex repressor; autorepressor
RA 118,873 G→T 70.7% D99Y (GAC→TAC)  pdhR → pyruvate dehydrogenase complex repressor; autorepressor
RA 119,002 G→T 9.4% D142Y (GAT→TAT)  pdhR → pyruvate dehydrogenase complex repressor; autorepressor
RA 123,870 G→T 28.9% P563P (CCG→CCT aceF → pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2
RA 142,460 T→A 74.1% F298Y (TTC→TAC)  yadE → putative polysaccharide deacetylase lipoprotein
RA 145,632 G→T 5.5% Q153K (CAG→AAG)  panB ← 3‑methyl‑2‑oxobutanoate hydroxymethyltransferase
RA 147,946 G→T 31.5% I47I (ATC→ATA yadK ← putative fimbrial‑like adhesin protein
RA 153,472 G→T 48.7% intergenic (‑102/+268) yadN ← / ← folK putative fimbrial‑like adhesin protein/2‑amino‑4‑hydroxy‑6‑hydroxymethyldihyropteridine pyrophosphokinase
RA 157,178 C→A 29.5% intergenic (‑87/+91) dksA ← / ← sfsA transcriptional regulator of rRNA transcription, DnaK suppressor protein/sugar fermentation stimulation protein A
RA 158,287 C→A 65.5% D78Y (GAC→TAC)  ligT ← 2'‑5' RNA ligase
RA 158,967 C→A 19.0% H126N (CAT→AAT)  hrpB → putative ATP‑dependent helicase
RA 161,068 A→C 9.0% intergenic (+47/‑149) hrpB → / → mrcB putative ATP‑dependent helicase/fused glycosyl transferase and transpeptidase
RA 161,171 G→T 13.7% intergenic (+150/‑46) hrpB → / → mrcB putative ATP‑dependent helicase/fused glycosyl transferase and transpeptidase
RA 170,868 C→A 7.3% V168F (GTT→TTT)  hemL ← glutamate‑1‑semialdehyde aminotransferase (aminomutase)
RA 177,994 C→T 5.5% V208V (GTC→GTT degP → serine endoprotease (protease Do), membrane‑associated
RA 188,863 T→A 6.1% D174E (GAT→GAA pyrH → uridylate kinase
RA 198,022 C→A 34.9% R189S (CGT→AGT)  lpxD → UDP‑3‑O‑(3‑hydroxymyristoyl)‑glucosamine N‑acyltransferase
JC 216,968 Δ3 bp 6.8% coding (446‑448/816 nt) metQ ← DL‑methionine transporter subunit
RA 230,579 C→T 100% E231K (GAA→AAA)  gloB ← hydroxyacylglutathione hydrolase
RA 232,142 G→T 5.0% I116I (ATC→ATA rnhA ← ribonuclease HI, degrades RNA of DNA‑RNA hybrids
RA 232,860 G→T 71.4% D103Y (GAT→TAT)  dnaQ → DNA polymerase III epsilon subunit
RA 233,053 A→C 15.3% D167A (GAT→GCT)  dnaQ → DNA polymerase III epsilon subunit
RA 238,195 G→T 48.9% V532V (GTC→GTA fadE ← acyl coenzyme A dehydrogenase
RA 238,605 A→T 5.9% Y396N (TAT→AAT)  fadE ← acyl coenzyme A dehydrogenase
RA 241,773 A→T 8.3% Y174N (TAC→AAC)  yafK ← L,D‑transpeptidase‑related protein
RA 248,470 A→C 12.6% intergenic (+30/‑22) dinB → / → yafN DNA polymerase IV/antitoxin of the YafO‑YafN toxin‑antitoxin system
RA 249,629 G→A 12.4% R145Q (CGA→CAA)  yafP → putative acyl‑CoA transferase
RA 281,469 A→T 5.6% T122S (ACC→TCC)  yagG → CP4‑6 prophage; putative sugar transporter
RA 301,808 C→A 6.8% E241* (GAA→TAA)  ecpD ← polymerized tip adhesin of ECP fibers
RA 306,510 G→A 19.4% R180W (CGG→TGG)  ecpR ← putative transcriptional regulator for the ecp operon
RA 306,949 G→A 7.7% A33A (GCC→GCT ecpR ← putative transcriptional regulator for the ecp operon
RA 312,532 G→A 57.1% pseudogene (349/684 nt) ykgA ← pseudogene, AraC family;putative regulator; Not classified; putative ARAC‑type regulatory protein
JC JC 312,806 IS2 (+) +5 bp 5.0% pseudogene (71‑75/684 nt) ykgA ← pseudogene, AraC family;putative regulator; Not classified; putative ARAC‑type regulatory protein
RA 320,920 G→A 48.7% S52S (AGC→AGT ykgH ← putative inner membrane protein
RA 334,250 G→T 18.9% R72L (CGT→CTT)  yahG → DUF1116 family protein
RA 341,060 C→A 13.1% intergenic (+358/‑55) yahL → / → yahM uncharacterized protein/uncharacterized protein
RA 351,359 G→T 18.6% G243C (GGT→TGT)  codB → cytosine transporter
RA 351,447 T→A 19.5% L272Q (CTG→CAG)  codB → cytosine transporter
RA 353,335 T→G 5.2% intergenic (+170/+167) codA → / ← cynR cytosine/isoguanine deaminase/transcriptional activator of cyn operon; autorepressor
RA 353,486 A→T 5.5% intergenic (+321/+16) codA → / ← cynR cytosine/isoguanine deaminase/transcriptional activator of cyn operon; autorepressor
RA 353,489 C→T 5.0% intergenic (+324/+13) codA → / ← cynR cytosine/isoguanine deaminase/transcriptional activator of cyn operon; autorepressor
RA 358,609 G→T 5.2% I94I (ATC→ATA lacY ← lactose permease
RA 359,028 C→A 6.1% pseudogene (1039/1125 nt) lacZ ← pseudogene, truncated
RA 360,752 A→G 100% V331A (GTG→GCG)  lacI ← DNA‑binding transcriptional repressor
JC 361,139 +GCCA 10.4% coding (605/1083 nt) lacI ← DNA‑binding transcriptional repressor
RA 361,806 G→A 100% intergenic (‑63/+14) lacI ← / ← mhpR DNA‑binding transcriptional repressor/mhp operon transcriptional activator
RA 362,159 G→T 55.1% I165I (ATC→ATA mhpR ← mhp operon transcriptional activator
RA 372,966 G→T 5.3% intergenic (+199/+25) yaiL → / ← frmB DUF2058 family protein/S‑formylglutathione hydrolase
RA 376,532 C→A 31.1% pseudogene (184/416 nt) yaiX ← pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase
RA 379,943 C→T 15.6% G44R (GGA→AGA)  yaiS ← putative PIG‑L family deacetylase
RA 379,966 G→A 15.5% S36L (TCG→TTG)  yaiS ← putative PIG‑L family deacetylase
RA 395,611 C→A 10.7% D257Y (GAC→TAC)  ddlA ← D‑alanine‑D‑alanine ligase A
RA 401,729 G→A 6.0% intergenic (+51/‑132) yaiI → / → aroL UPF0178 family protein/shikimate kinase II
RA 402,340 G→T 67.3% V160V (GTG→GTT aroL → shikimate kinase II
RA 406,075 C→A 72.8% P159Q (CCG→CAG)  mak → manno(fructo)kinase
RA 411,027 G→T 67.9% L61L (CTC→CTA sbcC ← exonuclease, dsDNA, ATP‑dependent
RA 419,663 G→T 24.6% E564* (GAA→TAA)  malZ → maltodextrin glucosidase
RA 433,551 G→T 66.8% S14Y (TCC→TAC)  yajO ← 2‑carboxybenzaldehyde reductase
RA 434,663 A→C 68.2% I324S (ATC→AGC)  dxs ← 1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring
RA 435,336 G→T 49.8% Q100K (CAG→AAG)  dxs ← 1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring
RA 437,672 T→A 51.0% V223E (GTG→GAG)  thiI → tRNA s(4)U8 sulfurtransferase
RA 442,299 G→T 16.2% S288* (TCG→TAG)  cyoE ← protoheme IX farnesyltransferase
RA 447,252 G→A 5.8% intergenic (‑186/+274) cyoA ← / ← ampG cytochrome o ubiquinol oxidase subunit II/muropeptide transporter
RA 456,588 G→T 67.3% D749Y (GAC→TAC)  lon → DNA‑binding ATP‑dependent protease La
RA 461,641 G→A 29.1% V376V (GTC→GTT ybaE ← putative ABC superfamily transporter periplasmic‑binding protein
RA 473,180 T→A 6.9% K298N (AAA→AAT ylaB ← putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 474,138 G→T 64.9% intergenic (‑65/+99) ylaB ← / ← ylaC putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase/DUF1449 family inner membrane protein
RA 479,244 C→A 48.0% A206S (GCC→TCC)  acrB ← multidrug efflux system protein
RA 480,820 C→T 71.2% D86N (GAC→AAC)  acrA ← multidrug efflux system
RA 495,504 A→T 26.5% intergenic (‑75/‑77) aes ← / → gsk acetyl esterase/inosine/guanosine kinase
RA 495,583 G→T 5.5% M1M (ATG→ATT) † gsk → inosine/guanosine kinase
RA 505,336 C→T 8.9% E500E (GAG→GAA copA ← copper transporter
RA 509,557 C→A 6.6% R37S (CGC→AGC)  cueR → copper‑responsive regulon transcriptional regulator
RA 513,720 T→C 8.8% I6V (ATT→GTT)  ybbN ← DnaK co‑chaperone, thioredoxin‑like protein
RA 525,424 T→C 17.1% pseudogene (49/357 nt) ylbG ← pseudogene, DNA‑binding transcriptional regulator homology
RA 530,466 C→A 70.0% F365L (TTC→TTA gcl → glyoxylate carboligase
RA 542,200 Δ1 bp 45.9% coding (65/1668 nt) fdrA → putative NAD(P)‑binding acyl‑CoA synthetase
RA 546,491 G→T 69.4% V199V (GTG→GTT ybcF → putative carbonate kinase
RA 549,397 G→T 72.6% intergenic (‑1/+2) lpxH ← / ← ppiB UDP‑2,3‑diacylglucosamine pyrophosphohydrolase/peptidyl‑prolyl cis‑trans isomerase B (rotamase B)
RA 553,502 C→A 5.8% intergenic (‑305/‑166) folD ← / → sfmA bifunctional 5,10‑methylene‑tetrahydrofolate dehydrogenase/ 5,10‑methylene‑tetrahydrofolate cyclohydrolase/FimA homolog
RA 565,317 G→A 6.6% A320A (GCG→GCA ybcK → DLP12 prophage; putative recombinase
RA 569,705 G→A 5.9% R98R (AGG→AGA quuD → DLP12 prophage; putative antitermination protein
RA 578,430 G→A 7.3% pseudogene (22/183 nt) tfaX → pseudogene, DLP12 prophage;Phage or Prophage Related
RA 579,710 G→A 24.4% A192T (GCA→ACA)  appY → global transcriptional activator; DLP12 prophage
RA 581,203 A→T 6.1% intergenic (‑114/‑310) ompT ← / → pauD DLP12 prophage; outer membrane protease VII (outer membrane protein 3b)/tRNA‑OTHER
RA 583,341 T→G 65.7% S33R (AGT→CGT)  ybcH ← PRK09936 family protein
RA 592,124 A→T 5.5% I357F (ATT→TTT)  cusC → copper/silver efflux system, outer membrane component
RA 595,736 C→A 8.3% R523S (CGT→AGT)  cusA → copper/silver efflux system, membrane component
RA 596,756 G→T 10.0% E863* (GAG→TAG)  cusA → copper/silver efflux system, membrane component
RA 599,256 C→T 8.2% A288A (GCG→GCA ybdG ← mechanosensitive channel protein, miniconductance
RA 601,154 T→A 14.3% L63F (TTA→TTT ybdF ← DUF419 family protein
RA 607,660 G→T 8.2% R97R (CGC→CGA fepA ← iron‑enterobactin outer membrane transporter
RA 607,931 G→A 65.2% S7F (TCC→TTC)  fepA ← iron‑enterobactin outer membrane transporter
RA 608,174 G→A 11.3% intergenic (‑224/‑19) fepA ← / → fes iron‑enterobactin outer membrane transporter/enterobactin/ferric enterobactin esterase
RA 625,364 G→T 31.7% G5G (GGG→GGT cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 627,794 G→A 5.3% D53N (GAC→AAC)  ybdD → DUF466 family protein
RA 632,406 T→A 36.2% K223N (AAA→AAT ybdO ← putative DNA‑binding transcriptional regulator
RA 639,231 G→A 66.4% L65F (CTT→TTT)  rnk ← regulator of nucleoside diphosphate kinase
RA 641,886 C→A 36.7% E51* (GAG→TAG)  citT ← citrate:succinate antiporter
RA 647,422 G→T 49.7% intergenic (‑110/‑269) citC ← / → citA [citrate [pro‑3S]‑lyase] ligase/sensory histidine kinase in two‑component regulatory system with CitB
RA 648,056 C→A 63.7% F122L (TTC→TTA citA → sensory histidine kinase in two‑component regulatory system with CitB
RA 652,865 Δ1 bp 62.5% coding (118/210 nt) cspE → constitutive cold shock family transcription antitermination protein; negative regulator of cspA transcription; RNA melting protein; ssDNA‑binding protein
RA 657,177 C→T 6.6% A186A (GCG→GCA lipB ← octanoyltransferase; octanoyl‑[ACP]:protein N‑octanoyltransferase
RA 660,816 G→A 16.6% V318V (GTC→GTT mrdB ← cell wall shape‑determining protein
RA 662,631 C→A 55.5% R348L (CGC→CTC)  mrdA ← transpeptidase involved in peptidoglycan synthesis (penicillin‑binding protein 2)
RA 663,449 G→T 7.5% N75K (AAC→AAA mrdA ← transpeptidase involved in peptidoglycan synthesis (penicillin‑binding protein 2)
RA 702,512 A→G 5.7% T322A (ACC→GCC)  glnS → glutamyl‑tRNA synthetase
RA 705,588 C→A 48.3% intergenic (+16/+68) chiQ → / ← fur chitosugar‑induced verified lipoprotein/ferric iron uptake regulon transcriptional repressor; autorepressor
RA 706,766 C→T 7.4% L52L (CTG→CTA fldA ← flavodoxin 1
RA 707,409 C→A 17.5% intergenic (‑55/+85) ybfE ← / ← ybfF LexA‑regulated protein, CopB family/acyl‑CoA esterase
RA 708,018 C→A 6.7% D81Y (GAC→TAC)  ybfF ← acyl‑CoA esterase
RA 731,316 A→T 8.9% T71S (ACA→TCA)  ybfC → putative periplasmic protein
RA 738,149 G→A 12.1% intergenic (‑137/‑134) dtpD ← / → ybgI dipeptide and tripeptide permease D/NIF3 family metal‑binding protein
RA 754,572 G→T 71.6% E137D (GAG→GAT sucA → 2‑oxoglutarate decarboxylase, thiamine triphosphate‑binding
RA 757,524 C→A 8.8% R183S (CGC→AGC)  sucB → dihydrolipoyltranssuccinase
RA 759,000 C→A 71.8% F177L (TTC→TTA sucC → succinyl‑CoA synthetase, beta subunit
RA 760,181 G→T 14.5% P182P (CCG→CCT sucD → succinyl‑CoA synthetase, NAD(P)‑binding, alpha subunit
RA 766,563 G→A 8.0% intergenic (+496/‑351) mngB → / → cydA alpha‑mannosidase/cytochrome d terminal oxidase, subunit I
RA 773,443 C→A 7.0% A83E (GCG→GAG)  tolB → periplasmic protein
RA 788,902 G→T 65.2% R115S (CGT→AGT)  modF ← fused molybdate transporter subunits of ABC superfamily: ATP‑binding components
RA 800,779 G→T 58.2% E607D (GAG→GAT ybhJ → putative hydratase
RA 828,374 G→T 67.2% V11V (GTC→GTA ybiA ← DUF1768 family protein
RA 832,574 G→T 9.7% T256T (ACG→ACT ybiC → putative dehydrogenase
RA 838,580 C→A 5.5% R265S (CGT→AGT)  rlmF → 23S rRNA m(6)A1618 methyltransferase, SAM‑dependent
RA 858,161 G→T 8.0% D269E (GAC→GAA ybiY ← putative pyruvate formate lyase activating enzyme
RA 864,209 G→A 6.6% A412T (GCT→ACT)  gsiA → glutathione transporter ATP‑binding protein, ABC superfamily
RA 868,618 G→T 10.8% E62* (GAA→TAA)  yliE → putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 871,072 C→A 7.6% V94V (GTC→GTA yliF → putative membrane‑anchored diguanylate cyclase
RA 874,768 G→T 18.8% E191* (GAA→TAA)  yliI → soluble aldose sugar dehydrogenase
RA 876,447 G→A 69.9% D89N (GAT→AAT)  dacC → D‑alanyl‑D‑alanine carboxypeptidase (penicillin‑binding protein 6a)
RA 879,085 G→T 70.0% intergenic (‑241/‑44) ybjG ← / → mdfA undecaprenyl pyrophosphate phosphatase/multidrug efflux system protein
RA 882,441 A→T 11.4% S119T (TCT→ACT)  ybjJ ← putative transporter
RA 890,514 G→T 5.1% R23L (CGC→CTC)  potG → putrescine transporter subunit: ATP‑binding component of ABC superfamily
JC JC 919,057 IS5 (–) +4 bp 6.8% coding (338‑341/2277 nt) clpA → ATPase and specificity subunit of ClpA‑ClpP ATP‑dependent serine protease, chaperone activity
RA 920,469 G→T 13.3% G584C (GGT→TGT)  clpA → ATPase and specificity subunit of ClpA‑ClpP ATP‑dependent serine protease, chaperone activity
RA 923,312 G→T 13.3% S447* (TCG→TAG)  cydC ← fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component
RA 923,339 G→T 10.4% S438* (TCG→TAG)  cydC ← fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component
RA 924,296 A→C 5.3% L119W (TTG→TGG)  cydC ← fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component
RA 927,201 G→C 5.1% G102G (GGC→GGG trxB ← thioredoxin reductase, FAD/NAD(P)‑binding
RA 932,915 C→A 7.2% R30S (CGC→AGC)  lolA → lipoprotein chaperone
RA 935,943 C→A 5.2% R354S (CGT→AGT)  serS → seryl‑tRNA synthetase, also charges selenocysteinyl‑tRNA with serine
RA 947,211 C→A 19.7% P600P (CCG→CCT pflB ← formate C‑acetyltransferase 1, anaerobic; pyruvate formate‑lyase 1
RA 950,103 T→C 9.2% intergenic (‑181/+225) focA ← / ← ycaO formate channel/ribosomal protein S12 methylthiotransferase accessory factor
RA 961,946 T→A 8.1% F724Y (TTT→TAT)  ycaI → ComEC family inner membrane protein
RA 968,415 G→T 68.2% S148* (TCG→TAG)  ycbC ← DUF218 superfamily protein
RA 971,532 A→T 12.4% Q152L (CAG→CTG)  mukE → chromosome condensin MukBEF, MukE localization factor
RA 982,037 G→T 5.7% T134T (ACC→ACA ompF ← outer membrane porin 1a (Ia;b;F)
RA 983,370 T→A 6.3% N358Y (AAC→TAC)  asnS ← asparaginyl tRNA synthetase
RA 1,006,218 G→T 13.0% E267* (GAG→TAG)  uup → putative transporter subunit of ABC superfamily: ATP‑binding component
RA 1,010,932 A→G 5.4% intergenic (+17/‑239) pqiC → / → rmf DUF330 family putative lipoprotein/ribosome modulation factor
RA 1,011,972 A→T 17.4% intergenic (‑46/+23) fabA ← / ← ycbZ beta‑hydroxydecanoyl thioester dehydrase/putative peptidase
RA 1,028,922 C→A 8.9% F71L (TTC→TTA hyaB → hydrogenase 1, large subunit
RA 1,050,246 G→T 16.2% L463L (CTC→CTA torS ← hybrid sensory histidine kinase in two‑component regulatory system with TorR
RA 1,077,911 A→C 72.7% K71N (AAA→AAC efeO → inactive ferrous ion transporter EfeUOB
RA 1,087,844 G→A 6.3% intergenic (‑99/‑488) pgaA ← / → ycdT biofilm adhesin polysaccharide PGA secretin; OM porin; poly‑beta‑1,6‑N‑acetyl‑D‑glucosamine export protein/diguanylate cyclase, membrane‑anchored
RA 1,090,918 T→A 22.2% intergenic (‑25/‑43) insE1 ← / → ymdE IS3 transposase A/pseudogene
RA 1,102,255 G→T 5.1% G149C (GGT→TGT)  clsC → stationary phase cardiolipin synthase 3
RA 1,116,964 A→G 63.6% intergenic (‑21/+53) dinI ← / ← pyrC DNA damage‑inducible protein I/dihydro‑orotase
RA 1,121,966 C→T 6.8% R118R (CGC→CGT yceH → UPF0502 family protein
RA 1,122,159 G→T 6.7% A183S (GCG→TCG)  yceH → UPF0502 family protein
RA 1,129,182 G→A 8.3% A385T (GCC→ACC)  flgE → flagellar hook protein
RA 1,129,363 G→A 20.5% A36T (GCG→ACG)  flgF → flagellar component of cell‑proximal portion of basal‑body rod
RA 1,129,816 G→T 7.0% A187S (GCC→TCC)  flgF → flagellar component of cell‑proximal portion of basal‑body rod
RA 1,136,758 T→A 8.5% A1022A (GCA→GCT rne ← fused ribonucleaseE: endoribonuclease/RNA‑binding protein/RNA degradosome binding protein
RA 1,151,750 G→T 46.3% R178L (CGC→CTC)  holB → DNA polymerase III, delta prime subunit
RA 1,152,278 G→T 72.3% E16* (GAA→TAA)  ycfH → putative DNase
RA 1,164,814 T→A 6.4% intergenic (+28/+54) bhsA → / ← ldtC biofilm, cell surface and signaling protein/L,D‑transpeptidase linking Lpp to murein
RA 1,192,525 C→T 13.5% S155N (AGC→AAC)  ymfD ← e14 prophage; putative SAM‑dependent methyltransferase
RA 1,193,313 C→T 5.7% M127I (ATG→ATA ymfE ← e14 prophage; putative inner membrane protein
RA 1,193,873 G→T 67.9% intergenic (‑180/‑278) ymfE ← / → lit e14 prophage; putative inner membrane protein/e14 prophage; cell death peptidase, inhibitor of T4 late gene expression
RA 1,194,365 G→T 22.7% W72L (TGG→TTG)  lit → e14 prophage; cell death peptidase, inhibitor of T4 late gene expression
RA 1,197,027 G→T 14.7% M25I (ATG→ATT ymfI → e14 prophage; uncharacterized protein
RA 1,197,734 C→T 9.1% R219K (AGA→AAA)  cohE ← e14 prophage; repressor protein phage e14
RA 1,210,957 C→A 9.4% intergenic (‑26/‑288) bluF ← / → ycgZ anti‑repressor for YcgE, blue light‑responsive; FAD‑binding; has c‑di‑GMP phosphodiesterase‑like EAL domain, but does not degrade c‑di‑GMP/RcsB connector protein for regulation of biofilm and acid‑resistance
RA 1,211,142 C→T 13.2% intergenic (‑211/‑103) bluF ← / → ycgZ anti‑repressor for YcgE, blue light‑responsive; FAD‑binding; has c‑di‑GMP phosphodiesterase‑like EAL domain, but does not degrade c‑di‑GMP/RcsB connector protein for regulation of biofilm and acid‑resistance
RA 1,215,174 G→T 21.8% pseudogene (118/2648 nt) ycgH → pseudogene; putative ATP‑binding component of a transport system
RA 1,216,183 C→A 8.0% pseudogene (1127/2648 nt) ycgH → pseudogene; putative ATP‑binding component of a transport system
RA 1,217,884 A→T 16.8% I69I (ATT→ATA ymgD ← uncharacterized protein
RA 1,218,640 C→T 6.2% intergenic (‑21/‑80) ymgI ← / → ymgJ uncharacterized protein/uncharacterized protein
RA 1,220,996 G→T 68.2% R181R (CGG→AGG)  minC ← cell division inhibitor
RA 1,228,591 G→T 68.3% intergenic (‑105/+41) dsbB ← / ← nhaB oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I/sodium:proton antiporter
RA 1,228,879 A→C 16.0% L432R (CTG→CGG)  nhaB ← sodium:proton antiporter
RA 1,229,460 G→T 17.3% F238L (TTC→TTA nhaB ← sodium:proton antiporter
RA 1,234,574 A→T 5.2% E80D (GAA→GAT dadX → alanine racemase, catabolic, PLP‑binding
RA 1,243,278 G→A 13.4% S431S (AGC→AGT dhaM ← putative dihydroxyacetone‑specific PTS enzymes: HPr component/EI component
RA 1,247,376 G→T 13.1% V285V (GTG→GTT dhaR → dhaKLM operon transcription activator
RA 1,282,421 A→T 7.1% intergenic (+439/+101) narI → / ← rttR nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript
RA 1,283,124 G→A 7.6% intergenic (‑46/+114) tyrT ← / ← purU tRNA‑Tyr/formyltetrahydrofolate hydrolase
RA 1,306,564 A→T 5.4% intergenic (‑61/+44) yciA ← / ← yciB acyl‑CoA esterase/IspA family inner membrane protein
RA 1,311,385 T→A 7.3% Q32L (CAG→CTG)  trpA ← tryptophan synthase, alpha subunit
RA 1,322,140 T→A 63.8% T159S (ACG→TCG)  btuR ← cob(I)yrinic acid a,c‑diamide adenosyltransferase
RA 1,326,970 C→A 5.6% H556N (CAC→AAC)  topA → DNA topoisomerase I, omega subunit
RA 1,343,362 C→T 5.5% A335T (GCC→ACC)  yciW ← putative oxidoreductase
RA 1,352,314 C→A 5.6% V377V (GTG→GTT puuP ← putrescine importer
RA 1,361,433 G→T 11.8% P246Q (CCG→CAG)  pspF ← psp operon transcriptional activator
RA 1,365,202 C→A 22.2% H244N (CAT→AAT)  ycjM → alpha amylase catalytic domain family protein
RA 1,365,283 G→T 40.9% E271* (GAG→TAG)  ycjM → alpha amylase catalytic domain family protein
RA 1,368,566 T→G 16.1% F74V (TTC→GTC)  ycjP → inner membrane putative ABC superfamily sugar transporter permease
JC JC 1,376,043 IS5 (–) +4 bp 88.9% pseudogene (10‑13/126 nt) ycjV → pseudogene; putative ATP‑binding component of a transport system
RA 1,377,394 C→T 69.8% A275A (GCG→GCA ycjW ← LacI family putative transcriptional repressor
RA 1,386,008 G→T 52.1% Q35K (CAG→AAG)  ycjY ← S9 homolog non‑peptidase family protein
RA 1,388,406 G→T 54.2% R308L (CGC→CTC)  mppA → murein tripeptide (L‑ala‑gamma‑D‑glutamyl‑meso‑DAP) transporter subunit
RA 1,397,506 C→T 5.4% E3K (GAA→AAA)  abgB ← p‑aminobenzoyl‑glutamate hydrolase, B subunit
RA 1,402,363 G→A 5.4% M19I (ATG→ATA ydaN → putative Zn(II) transporter
RA 1,413,956 G→T 8.8% intergenic (‑243/+66) ydaG ← / ← racR Rac prophage; uncharacterized protein/Rac prophage; putative DNA‑binding transcriptional regulator
RA 1,444,986 C→T 6.8% W207* (TGG→TGA tynA ← tyramine oxidase, copper‑requiring
RA 1,445,782 C→T 7.4% intergenic (‑176/+72) tynA ← / ← paaZ tyramine oxidase, copper‑requiring/fused oxepin‑CoA hydrolase/3‑oxo‑5,6‑dehydrosuberyl‑CoA semialdehyde dehydrogenase
RA 1,460,458 T→C 5.8% pseudogene (810/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,461,652 G→T 9.5% pseudogene (2004/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,471,707 A→T 30.7% *769C (TGA→TGT ydbD → PF10971 family putative periplasmic methylglyoxal resistance protein
RA 1,503,048 G→T 5.3% intergenic (+49/+43) ydcP → / ← yncJ putative peptidase/uncharacterized protein
RA 1,506,689 A→T 5.5% Q260L (CAG→CTG)  ydcS → polyhydroxybutyrate (PHB) synthase, ABC transporter periplasmic binding protein homolog
RA 1,513,440 T→A 7.6% Y53N (TAT→AAT)  curA → curcumin/dihydrocurcumin reductase, NADPH‑dependent
RA 1,519,349 T→A 67.6% K297* (AAA→TAA)  ansP ← L‑asparagine transporter
RA 1,524,654 G→T 18.7% W159L (TGG→TTG)  ydcD → uncharacterized protein
RA 1,538,906 G→A 16.2% pseudogene (116/381 nt) yddK ← pseudogene, leucine‑rich protein; putative glycoportein
RA 1,539,484 G→A 10.4% pseudogene (488/951 nt) yddK ← pseudogene, leucine‑rich protein; putative glycoportein
RA 1,548,144 G→T 58.4% intergenic (‑49/+85) adhP ← / ← maeA ethanol‑active dehydrogenase/acetaldehyde‑active reductase/malate dehydrogenase, (decarboxylating, NAD‑requiring) (malic enzyme)
RA 1,563,276 G→T 74.5% H491N (CAC→AAC)  gadC ← glutamate:gamma‑aminobutyric acid antiporter
RA 1,565,497 G→A 58.1% S269L (TCG→TTG)  gadB ← glutamate decarboxylase B, PLP‑dependent
RA 1,576,869 G→A 15.6% intergenic (‑88/+314) ydeN ← / ← ydeO putative Ser‑type periplasmic non‑aryl sulfatase/UV‑inducible global regulator, EvgA‑, GadE‑dependent
RA 1,587,275 C→A 6.9% pseudogene (4970/5323 nt) yneO ← pseudogene, AidA homolog
RA 1,588,055 C→A 5.5% pseudogene (4190/5323 nt) yneO ← pseudogene, AidA homolog
RA 1,599,970 T→A 9.2% D221E (GAT→GAA lsrB → autoinducer 2‑binding protein
RA 1,604,068 G→T 21.8% T290T (ACC→ACA uxaB ← altronate oxidoreductase, NAD‑dependent
RA 1,607,556 A→C 16.2% intergenic (‑48/+16) glsB ← / ← sad glutaminase 2/succinate semialdehyde dehydrogenase, NAD(P)+‑dependent
RA 1,611,821 C→A 8.1% I179I (ATC→ATA ydeA → arabinose efflux transporter, arabinose‑inducible
RA 1,628,207 G→A 89.3% G110E (GGA→GAA)  pinQ → Qin prophage; putative site‑specific recombinase
RA 1,640,268 A→C 19.7% K39Q (AAG→CAG)  ydfV → Qin prophage; uncharacterized protein
RA 1,641,686 G→A 8.0% pseudogene (208/279 nt) ydfX ← pseudogene, Qin prophage;Phage or Prophage Related
RA 1,649,456 C→T 19.6% intergenic (‑58/+148) rspA ← / ← ynfA bifunctional D‑altronate/D‑mannonate dehydratase/UPF0060 family inner membrane protein
RA 1,649,576 A→C 5.0% intergenic (‑178/+28) rspA ← / ← ynfA bifunctional D‑altronate/D‑mannonate dehydratase/UPF0060 family inner membrane protein
RA 1,652,812 A→T 7.2% I163F (ATC→TTC)  ynfE → putative selenate reductase, periplasmic
RA 1,661,763 C→A 74.2% P353P (CCG→CCT mlc ← glucosamine anaerobic growth regulon transcriptional repressor; autorepressor
RA 1,694,980 G→T 5.3% E457* (GAA→TAA)  malX → fused maltose and glucose‑specific PTS enzymes: IIB component, IIC component
RA 1,700,047 T→C 5.7% F8F (TTT→TTC rsxA → SoxR iron‑sulfur cluster reduction factor component; inner membrane protein of electron transport complex
RA 1,703,062 T→A 8.6% R629R (CGT→CGA rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,703,101 C→G 7.0% A642A (GCC→GCG rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,704,060 A→T 9.1% Q221L (CAA→CTA)  rsxD → SoxR iron‑sulfur cluster reduction factor component; putative membrane protein of electron transport complex
RA 1,711,397 C→T 60.6% R28Q (CGA→CAA)  tyrS ← tyrosyl‑tRNA synthetase
RA 1,716,193 A→T 5.1% S225C (AGT→TGT)  ydhJ → putative membrane fusion protein (MFP) of YdhJK efflux pump
RA 1,722,491 T→A 6.7% L133Q (CTG→CAG)  gloA → glyoxalase I, Ni‑dependent
RA 1,726,289 A→T 9.1% P982P (CCA→CCT lhr → putative ATP‑dependent helicase
RA 1,748,094 T→A 9.2% intergenic (‑7/+14) ydhV ← / ← ydhY putative oxidoreductase subunit/putative 4Fe‑4S ferridoxin‑type protein; FNR, Nar, NarP‑regulated protein; putative subunit of YdhYVWXUT oxidoreductase complex
RA 1,770,281 T→A 49.8% D146E (GAT→GAA ydiF → putative acetyl‑CoA:acetoacetyl‑CoA transferase: alpha subunit/beta subunit
RA 1,780,104 C→A 10.3% A422A (GCG→GCT ppsA ← phosphoenolpyruvate synthase
RA 1,784,836 A→T 10.3% V222V (GTT→GTA ydiU ← UPF0061 family protein
RA 1,784,952 A→G 19.0% F184L (TTT→CTT)  ydiU ← UPF0061 family protein
RA 1,788,683 C→T 5.8% V243I (GTT→ATT)  btuC ← vitamin B12 transporter subunit: membrane component of ABC superfamily
RA 1,795,380 A→T 6.5% V483E (GTA→GAA)  thrS ← threonyl‑tRNA synthetase
RA 1,802,047 G→A 66.7% intergenic (+100/‑6) ydiZ → / → yniA uncharacterized protein/fructosamine kinase family protein
RA 1,807,639 G→A 12.6% intergenic (‑250/+39) ydjO ← / ← cedA uncharacterized protein/cell division modulator
RA 1,822,626 A→C 5.7% W456G (TGG→GGG)  astD ← succinylglutamic semialdehyde dehydrogenase
RA 1,824,998 G→T 6.2% R9R (CGA→AGA)  astA ← arginine succinyltransferase
RA 1,832,413 C→A 52.3% L315L (CTC→CTA ynjC → inner membrane putative ABC superfamily transporter permease
RA 1,833,730 C→A 67.4% R3S (CGT→AGT)  ynjE → molybdopterin synthase sulfurtransferase
RA 1,849,412 T→A 8.2% T273S (ACT→TCT)  ydjG ← alpha‑Keto reductase, NADH‑dependent; can use methylglyoxal as substrate
RA 1,865,422 C→A 69.3% R261R (CGA→AGA)  yeaI → putative membrane‑anchored diguanylate cyclase
RA 1,872,520 G→T 67.7% P183P (CCG→CCT yeaP → diguanylate cyclase
RA 1,875,105 G→C 6.5% intergenic (‑89/+38) leuE ← / ← dmlR leucine efflux protein/transcriptional activator of dmlA
RA 1,884,059 G→A 8.2% intergenic (‑56/+149) fadD ← / ← yeaY acyl‑CoA synthetase (long‑chain‑fatty‑acid‑‑CoA ligase)/Slp family lipoprotein, RpoE‑regulated
RA 1,906,096 T→A 5.3% K246N (AAA→AAT htpX ← putative endopeptidase
RA 1,906,578 C→A 7.9% A86S (GCT→TCT)  htpX ← putative endopeptidase
RA 1,909,342 T→A 66.4% E150D (GAA→GAT proQ ← RNA chaperone, putative ProP translation regulator
RA 1,909,792 G→T 7.2% intergenic (‑1/+96) proQ ← / ← msrC RNA chaperone, putative ProP translation regulator/free methionine‑(R)‑sulfoxide reductase
RA 1,915,555 A→C 22.6% Q359P (CAG→CCG)  rsmF → 16S rRNA m(5)C1407 methyltransferase, SAM‑dependent
RA 1,924,898 T→A 7.9% D36V (GAT→GTT)  yebG ← DNA damage‑inducible protein regulated by LexA
RA 1,934,690 G→T 7.4% N401K (AAC→AAA mepM ← murein DD‑endopeptidase, space‑maker hydrolase, septation protein
RA 1,936,668 G→A 5.3% S58L (TCA→TTA)  znuA ← zinc transporter subunit: periplasmic‑binding component of ABC superfamily
RA 1,944,177 C→A 42.9% L201L (CTG→CTT aspS ← aspartyl‑tRNA synthetase
RA 1,984,340 G→A 5.4% L393L (TTG→TTA tyrP → tyrosine transporter
RA 1,995,152 T→A 13.6% E40V (GAA→GTA)  fliA ← RNA polymerase, sigma 28 (sigma F) factor
RA 2,020,166 C→A 47.2% D445Y (GAC→TAC)  yedQ ← putative membrane‑anchored diguanylate cyclase
RA 2,048,571 A→T 14.4% P10P (CCA→CCT amn → AMP nucleosidase
RA 2,056,803 A→T 7.7% M1K (ATG→AAG) † ldtA ← L,D‑transpeptidase linking Lpp to murein
RA 2,064,561 G→T 5.7% pseudogene (421/552 nt) yeeP → pseudogene, CP4‑44 prophage; 50S ribosome‑binding GTPase family;Phage or Prophage Related; putative histone
RA 2,070,058 C→A 17.4% A90A (GCC→GCA yeeS → CP4‑44 prophage; putative DNA repair protein
RA 2,078,521 C→A 27.1% V162V (GTG→GTT yeeE ← UPF0394 family inner membrane protein
RA 2,094,530 C→T 7.1% V74M (GTG→ATG)  gnd ← 6‑phosphogluconate dehydrogenase, decarboxylating
RA 2,098,995 C→A 63.4% G182* (GGA→TGA)  wbbI ← d‑Galf:alpha‑d‑Glc beta‑1,6‑galactofuranosyltransferase
RA 2,102,316 A→T 7.1% F250L (TTT→TTA wzxB ← putative polisoprenol‑linked O‑antigen transporter
RA 2,114,911 A→T 49.8% L42Q (CTG→CAG)  wcaJ ← colanic biosynthesis UDP‑glucose lipid carrier transferase
RA 2,120,252 T→A 5.8% K140N (AAA→AAT wcaG ← bifunctional GDP‑fucose synthetase: GDP‑4‑dehydro‑6‑deoxy‑D‑mannose epimerase/ GDP‑4‑dehydro‑6‑L‑deoxygalactose reductase
RA 2,120,334 T→C 6.2% K113R (AAA→AGA)  wcaG ← bifunctional GDP‑fucose synthetase: GDP‑4‑dehydro‑6‑deoxy‑D‑mannose epimerase/ GDP‑4‑dehydro‑6‑L‑deoxygalactose reductase
RA 2,136,421 A→G 7.8% D3D (GAT→GAC udk ← uridine/cytidine kinase
RA 2,139,910 G→T 68.9% R1055L (CGA→CTA)  yegE → putative diguanylate cyclase
RA 2,144,474 C→A 72.6% intergenic (‑8/‑192) yegI ← / → yegJ protein kinase‑related putative non‑specific DNA‑binding protein/uncharacterized protein
RA 2,166,765 C→T 5.6% P331P (CCG→CCA gatC ← galactitol PTS permease ‑ GatC subunit
RA 2,170,285 C→T 11.7% A133A (GCG→GCA gatY ← D‑tagatose 1,6‑bisphosphate aldolase 2, catalytic subunit
RA 2,195,449 A→T 74.3% E564D (GAA→GAT yehI → DUF4132 domain‑containing protein
RA 2,216,296 C→A 46.4% I211I (ATC→ATA dld → D‑lactate dehydrogenase, FAD‑binding, NADH independent
RA 2,226,194 T→A 5.9% V291E (GTG→GAG)  cdd → cytidine/deoxycytidine deaminase
RA 2,237,098 G→T 52.6% H12N (CAT→AAT)  folE ← GTP cyclohydrolase I
RA 2,240,469 G→T 5.2% intergenic (‑221/+73) cirA ← / ← lysP colicin IA outer membrane receptor and translocator; ferric iron‑catecholate transporter/lysine transporter
RA 2,242,501 C→A 12.9% E199D (GAG→GAT yeiE ← putative DNA‑binding transcriptional regulator
RA 2,254,517 C→T 21.3% A125T (GCC→ACC)  fruA ← fused fructose‑specific PTS enzymes: IIBcomponent/IIC components
RA 2,258,182 A→T 12.1% K281* (AAG→TAG)  setB → lactose/glucose efflux system
RA 2,258,546 C→T 5.2% D77N (GAT→AAT)  yeiW ← UPF0153 cysteine cluster protein
RA 2,264,143 G→A 46.9% intergenic (+119/‑62) mepS → / → rtn murein DD‑endopeptidase, space‑maker hydrolase, mutational suppressor of prc thermosensitivity, outer membrane lipoprotein/resistance protein for phages lambda and N4, putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 2,289,287 C→A 7.9% P171P (CCG→CCT ccmC ← heme exporter subunit
RA 2,289,374 C→A 62.6% V142V (GTG→GTT ccmC ← heme exporter subunit
RA 2,293,295 C→T 5.7% V149I (GTT→ATT)  napG ← ferredoxin‑type protein essential for electron transfer from ubiquinol to periplasmic nitrate reductase (NapAB)
RA 2,295,607 A→G 8.6% F209S (TTT→TCT)  napA ← nitrate reductase, periplasmic, large subunit
RA 2,295,611 C→T 11.8% A208T (GCG→ACG)  napA ← nitrate reductase, periplasmic, large subunit
RA 2,298,492 A→G 7.6% intergenic (+620/+95) eco → / ← mqo ecotin, a serine protease inhibitor/malate dehydrogenase, FAD/NAD(P)‑binding domain
RA 2,302,650 C→A 16.2% M57I (ATG→ATT alkB ← oxidative demethylase of N1‑methyladenine or N3‑methylcytosine DNA lesions
RA 2,305,116 C→A 65.2% intergenic (‑103/+9) apbE ← / ← ompC putative thiamine‑synthetic flavin transferase lipoprotein/outer membrane porin protein C
RA 2,321,444 T→A 6.5% D60V (GAT→GTT)  yfaP ← DUF2135 family protein, putative host defense protein
RA 2,328,078 A→T 6.6% Y121N (TAC→AAC)  yfaT ← DUF1175 family protein, putative host defense protein
RA 2,338,611 C→A 7.5% R90S (CGT→AGT)  nrdA → ribonucleoside‑diphosphate reductase 1, alpha subunit
RA 2,348,261 Δ1 bp 6.9% coding (518/1260 nt) glpB → sn‑glycerol‑3‑phosphate dehydrogenase (anaerobic), membrane anchor subunit
RA 2,352,573 C→A 66.4% P353P (CCG→CCT rhmT ← putative L‑rhamnonate transporter
RA 2,359,673 G→T 62.7% M89I (ATG→ATT arnB → uridine 5'‑(beta‑1‑threo‑pentapyranosyl‑4‑ulose diphosphate) aminotransferase, PLP‑dependent
RA 2,362,338 T→A 72.7% L274Q (CTG→CAG)  arnA → fused UDP‑L‑Ara4N formyltransferase/UDP‑GlcA C‑4'‑decarboxylase
RA 2,367,110 G→A 7.5% intergenic (‑93/+17) pmrD ← / ← menE inactive two‑component system connector protein/O‑succinylbenzoate‑CoA ligase
RA 2,368,150 C→A 5.1% T111T (ACG→ACT menE ← O‑succinylbenzoate‑CoA ligase
RA 2,370,361:1 +G 66.4% coding (711/759 nt) menH ← 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase
RA 2,370,841 G→A 5.8% I77I (ATC→ATT menH ← 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase
RA 2,370,987 C→A 65.8% E29* (GAA→TAA)  menH ← 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase
RA 2,376,381 G→A 9.3% A64T (GCT→ACT)  elaD → protease, capable of cleaving an AMC‑ubiquitin model substrate
RA 2,381,131 G→A 5.4% intergenic (+215/+58) yfbM → / ← yfbN DUF1877 family protein/uncharacterized protein
RA 2,390,862 C→A 17.9% V20V (GTG→GTT nuoH ← NADH:ubiquinone oxidoreductase, membrane subunit H
RA 2,403,195 G→T 7.7% S546* (TCG→TAG)  yfbS ← putative transporter
RA 2,405,946 T→G 70.7% Q43P (CAG→CCG)  yfbU ← UPF0304 family protein
RA 2,407,141 G→T 6.5% E65* (GAA→TAA)  ackA → acetate kinase A and propionate kinase 2
RA 2,407,495 G→T 12.0% G183C (GGC→TGC)  ackA → acetate kinase A and propionate kinase 2
RA 2,410,498 G→A 5.6% intergenic (+128/‑62) pta → / → yfcC phosphate acetyltransferase/putative inner membrane transporter, C4‑dicarboxylate anaerobic carrier family
RA 2,422,841 C→A 66.6% D293Y (GAT→TAT)  purF ← amidophosphoribosyltransferase
RA 2,424,074 C→T 63.6% D57N (GAC→AAC)  cvpA ← colicin V production membrane protein
RA 2,446,543 G→A 5.0% pseudogene (1938/2646 nt) yfcU ← pseudogene, FimD fimbrial export usher family;putative membrane; Not classified; putative outer membrane protein
RA 2,450,335 C→T 70.9% intergenic (‑44/+159) sixA ← / ← fadJ phosphohistidine phosphatase/fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase
RA 2,454,297 T→G 48.1% E39D (GAA→GAC yfcZ ← UPF0381 family protein
RA 2,463,037 C→T 5.4% A143V (GCA→GTA)  gtrS → serotype‑specific glucosyl transferase, CPS‑53 (KpLE1) prophage
RA 2,465,705 G→T 6.0% pseudogene (162/270 nt) yfdM ← CPS‑53 (KpLE1) prophage; putative methyltransferase;Phage or Prophage Related
RA 2,474,418 G→T 68.7% S413* (TCA→TAA)  emrY ← putative multidrug efflux system
RA 2,475,283 G→T 10.3% P125T (CCA→ACA)  emrY ← putative multidrug efflux system
RA 2,491,075 C→A 5.2% D234Y (GAT→TAT)  alaC ← valine‑pyruvate aminotransferase 3
RA 2,493,283 C→A 12.5% N378K (AAC→AAA ypdA → sensor kinase regulating yhjX; pyruvate‑responsive YpdAB two‑component system
RA 2,520,863 G→T 16.6% D187Y (GAC→TAC)  yfeH → putative inorganic ion transporter
RA 2,525,695 C→T 5.1% intergenic (+112/‑73) cysZ → / → cysK EI24 family inner membrane protein; putative sulfate transporter/cysteine synthase A, O‑acetylserine sulfhydrolase A subunit
RA 2,548,703 C→T 5.4% E129K (GAA→AAA)  eutK ← putative ethanol utilization carboxysome structural protein
RA 2,551,235 C→T 5.0% A268A (GCG→GCA eutB ← ethanolamine ammonia‑lyase, large subunit, heavy chain
RA 2,553,563 T→G 8.3% intergenic (+138/‑53) intZ → / → yffL CPZ‑55 prophage; putative phage integrase/CPZ‑55 prophage; uncharacterized protein
RA 2,556,774 G→A 16.0% intergenic (+298/‑177) yffP → / → yffQ CPZ‑55 prophage; uncharacterized protein/CPZ‑55 prophage; uncharacterized protein
RA 2,576,254 G→A 7.0% intergenic (‑118/+8) ypfG ← / ← nudK DUF1176 family protein/GDP‑mannose pyrophosphatase
RA 2,576,325 C→A 68.2% E171D (GAG→GAT nudK ← GDP‑mannose pyrophosphatase
RA 2,587,029:1 +G 63.7% coding (101/699 nt) ypfH ← palmitoyl‑CoA esterase activity, uncertain physiological substrate
RA 2,595,292 C→A 6.8% S39* (TCG→TAG)  hyfB → hydrogenase 4, membrane subunit
RA 2,605,882 C→A 5.5% S208R (AGC→AGA hyfR → hydrogenase‑4 transcriptional activator
RA 2,606,516 G→T 63.2% D420Y (GAC→TAC)  hyfR → hydrogenase‑4 transcriptional activator
RA 2,609,187 C→A 28.2% A18A (GCG→GCT yfgO ← putative UPF0118 family inner membrane permease
RA 2,614,168 C→A 62.4% D22Y (GAT→TAT)  upp ← uracil phosphoribosyltransferase
RA 2,622,827 C→T 6.2% P60L (CCG→CTG)  yfgG → uncharacterized protein
RA 2,644,397 A→T 5.9% L417* (TTG→TAG)  yfhM ← bacterial alpha2‑macroglobulin colonization factor ECAM; anti‑host protease defense factor; periplasmic inner membrane‑anchored lipoprotein
RA 2,651,665 G→T 71.1% G210G (GGC→GGA hscA ← DnaK‑like molecular chaperone specific for IscU
RA 2,653,668 G→T 8.7% intergenic (‑20/+8) iscU ← / ← iscS iron‑sulfur cluster assembly scaffold protein/cysteine desulfurase (tRNA sulfurtransferase), PLP‑dependent
RA 2,654,099 C→A 18.7% A264A (GCG→GCT iscS ← cysteine desulfurase (tRNA sulfurtransferase), PLP‑dependent
RA 2,654,144 G→T 9.6% I249I (ATC→ATA iscS ← cysteine desulfurase (tRNA sulfurtransferase), PLP‑dependent
RA 2,657,436 C→T 5.5% D212D (GAC→GAT suhB → inositol monophosphatase
RA 2,657,523 C→T 5.4% N241N (AAC→AAT suhB → inositol monophosphatase
RA 2,665,296 C→T 6.7% S238L (TCG→TTG)  hcaB → 2,3‑dihydroxy‑2,3‑dihydrophenylpropionate dehydrogenase
RA 2,671,274 C→A 69.1% T149T (ACG→ACT yphE ← putative sugar transporter subunit of ABC superfamily, ATP‑binding component
RA 2,674,941 G→T 26.7% I388I (ATC→ATA yphG ← DUF4380 domain‑containing TPR repeat protein
RA 2,679,933 C→A 22.1% A247D (GCT→GAT)  hmp → fused nitric oxide dioxygenase/dihydropteridine reductase 2
RA 2,681,873 T→A 72.1% Q97L (CAG→CTG)  glrR ← response regulator regulating glmY sRNA in two‑component system with sensor protein GlrK
RA 2,684,388 G→A 6.1% L24L (CTG→TTG)  glrK ← sensor protein kinase regulating glmY sRNA in two‑component system with response regulator GlrR
RA 2,694,471 G→A 6.4% I206I (ATC→ATT pdxJ ← pyridoxine 5'‑phosphate synthase
RA 2,708,587 C→A 10.6% T31T (ACG→ACT yfiE ← putative DNA‑binding transcriptional regulator
RA 2,715,643 G→T 72.7% E778* (GAA→TAA)  pka → protein lysine acetyltransferase
RA 2,718,953 G→T 27.6% I51I (ATC→ATA kgtP ← alpha‑ketoglutarate transporter
RA 2,719,426 T→C 100% intergenic (‑321/+2) kgtP ← / ← rrfG alpha‑ketoglutarate transporter/5S ribosomal RNA of rrnG operon
RA 2,722,762 G→T 5.5% noncoding (42/76 nt) gltW ← tRNA‑Glu
RA 2,740,398 C→T 7.8% D253N (GAT→AAT)  ffh ← Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)
RA 2,756,275 C→A 5.9% E209* (GAG→TAG)  yfjK ← DEAD/H helicase‑like protein, CP4‑57 putative defective prophage
RA 2,759,184 C→T 11.1% intergenic (‑49/‑93) yfjM ← / → rnlA CP4‑57 prophage; uncharacterized protein/CP4‑57 prophage; RNase LS
RA 2,767,403 G→A 15.2% D243N (GAT→AAT)  yfjW → CP4‑57 prophage; putative inner membrane protein
RA 2,771,358 G→A 40.1% intergenic (+217/+147) ypjF → / ← ypjA CP4‑57 prophage; toxin of the YpjF‑YfjZ toxin‑antitoxin system/adhesin‑like autotransporter
RA 2,775,830 C→T 25.0% D86N (GAT→AAT)  ypjA ← adhesin‑like autotransporter
RA 2,777,166 A→T 12.9% pseudogene (1205/1374 nt) ypjC ← pseudogene
RA 2,777,493 T→G 6.0% pseudogene (878/1374 nt) ypjC ← pseudogene
RA 2,787,152 G→T 6.0% A353A (GCG→GCT gabT → 4‑aminobutyrate aminotransferase, PLP‑dependent
RA 2,793,020 C→T 6.9% E112K (GAA→AAA)  ygaC ← uncharacterized protein
RA 2,811,566 C→A 5.4% noncoding (68/77 nt) argY ← tRNA‑Arg
RA 2,812,983 C→T 6.4% Q796Q (CAG→CAA alaS ← alanyl‑tRNA synthetase
RA 2,825,783 C→T 70.7% intergenic (‑135/‑52) norR ← / → norV anaerobic nitric oxide reductase DNA‑binding transcriptional activator/anaerobic nitric oxide reductase flavorubredoxin
RA 2,835,413 C→A 17.6% I355I (ATC→ATA ascB → cryptic 6‑phospho‑beta‑glucosidase
RA 2,850,790 C→A 73.4% I113I (ATC→ATA mutS → methyl‑directed mismatch repair protein
RA 2,873,087 G→T 60.9% V15V (GTC→GTA ygbT ← multifunctional endonuclease Cas1, CRISPR adaptation protein; DNA repair enzyme
RA 2,876,760 C→T 65.4% G246G (GGG→GGA casA ← CRISP RNA (crRNA) containing Cascade antiviral complex protein
RA 2,878,668 G→T 41.6% V637V (GTC→GTA ygcB ← R‑loop helicase‑annealase Cas3 needed for Cascade anti‑viral activity
RA 2,890,873 A→T 19.3% I119I (ATT→ATA ygcS ← putative transporter
RA 2,893,420 C→A 7.0% M71I (ATG→ATT ygcW ← putative dehydrogenase
RA 2,928,446 G→T 20.8% A285S (GCT→TCT)  fucP → L‑fucose transporter
RA 2,929,196 C→A 6.8% T85K (ACG→AAG)  fucI → L‑fucose isomerase
RA 2,931,717 C→A 68.3% N307K (AAC→AAA fucK → L‑fuculokinase
RA 2,934,843 G→T 72.8% H50N (CAT→AAT)  ygdD ← UPF0382 family inner membrane protein
RA 2,940,829 A→T 7.9% intergenic (+7/‑27) metZ → / → metW tRNA‑Met/tRNA‑Met
RA 2,953,398 C→A 8.2% G797V (GGC→GTC)  recC ← exonuclease V (RecBCD complex), gamma chain
RA 2,975,754 T→A 5.1% intergenic (‑213/+102) araE ← / ← kduD arabinose transporter/hexuronate dehydrogenase; hexuronate utilization in high osmolarity
RA 2,979,880 C→A 10.2% H225Q (CAC→CAA yqeG → putative transporter
RA 2,982,873 G→T 9.9% G71* (GGA→TGA)  yqeJ → uncharacterized protein
RA 2,983,868 G→T 23.2% intergenic (‑149/‑45) yqeK ← / → ygeF uncharacterized protein/pseudogene
RA 2,988,774 C→A 10.9% pseudogene (346/447 nt) ygeN ← pseudogene
RA 2,989,295 C→A 61.8% pseudogene (85/261 nt) ygeN ← pseudogene
RA 2,993,195 A→G 8.4% V19A (GTT→GCT)  ygeR ← LysM domain‑containing M23 family putative peptidase; septation lipoprotein
RA 2,993,211 C→A 70.3% V14L (GTG→TTG)  ygeR ← LysM domain‑containing M23 family putative peptidase; septation lipoprotein
RA 2,995,769 T→A 5.4% L689Q (CTG→CAG)  xdhA → xanthine dehydrogenase, molybdenum binding subunit
RA 3,001,919 C→A 9.2% H351N (CAT→AAT)  ygeX → 2,3‑diaminopropionate ammonia lyase, PLP‑dependent
RA 3,010,725 A→G 6.9% K436R (AAA→AGA)  ygfK → putative Fe‑S subunit oxidoreductase subunit
RA 3,013,226 C→A 7.0% S236Y (TCC→TAC)  ssnA → putative chlorohydrolase/aminohydrolase
RA 3,017,288 G→A 6.7% A872T (GCC→ACC)  xdhD → putative hypoxanthine oxidase, molybdopterin‑binding/Fe‑S binding
RA 3,020,228 G→T 13.4% A368A (GCG→GCT guaD → guanine deaminase
RA 3,020,629 C→A 26.2% I50I (ATC→ATA ygfQ → putative purine permease
RA 3,024,983 C→G 43.0% G86G (GGC→GGG uacT → uric acid permease
RA 3,033,430 G→T 14.8% D73Y (GAC→TAC)  fldB → flavodoxin 2
RA 3,044,464 G→A 72.6% intergenic (‑438/+10) gcvT ← / ← ubiI aminomethyltransferase, tetrahydrofolate‑dependent, subunit (T protein) of glycine cleavage complex/2‑octaprenylphenol hydroxylase, FAD‑dependent
RA 3,050,166 C→A 19.3% intergenic (+18/‑42) fau → / → sibC 5‑formyltetrahydrofolate cyclo‑ligase family protein/sRNA antisense regulator of toxic IbsC protein
RA 3,050,591 C→A 9.6% A393A (GCG→GCT serA ← D‑3‑phosphoglycerate dehydrogenase
RA 3,075,114 C→A 66.2% intergenic (‑120/‑158) tktA ← / → loiP transketolase 1, thiamine triphosphate‑binding/Phe‑Phe periplasmic metalloprotease, OM lipoprotein; low salt‑inducible; heat shock protein that binds Era
RA 3,076,526 C→A 50.6% D211Y (GAC→TAC)  speB ← agmatinase
RA 3,079,934 T→C 5.0% intergenic (+173/‑131) yqgC → / → metK uncharacterized protein/S‑adenosylmethionine synthetase
RA 3,080,618 T→A 62.9% V185E (GTG→GAG)  metK → S‑adenosylmethionine synthetase
RA 3,096,752 G→T 8.6% S127S (TCG→TCT mutY → adenine DNA glycosylase
RA 3,103,319 C→T 19.7% I136I (ATC→ATT yqgA → DUF554 family putative inner membrane protein
RA 3,105,207 G→T 6.5% pseudogene (243/963 nt) yghE ← pseudogene, secretion pathway protein, L‑type protein homology; putative general secretion pathway for protein export (GSP)
RA 3,111,434 C→A 69.0% A346A (GCG→GCT yghJ ← DUF4092 family putative lipoprotein peptidase
RA 3,116,216 G→T 5.2% R317S (CGT→AGT)  glcB ← malate synthase G
RA 3,120,216 C→A 69.4% D389Y (GAT→TAT)  glcD ← glycolate oxidase subunit, FAD‑linked
RA 3,126,414 C→A 7.1% R53L (CGG→CTG)  yghR ← putative ATP‑binding protein
RA 3,134,523 G→T 5.7% G41G (GGC→GGA hybD ← maturation protease for hydrogenase 2
RA 3,137,584 C→T 7.2% G306S (GGC→AGC)  hybA ← hydrogenase 2 4Fe‑4S ferredoxin‑type component
RA 3,137,675 C→T 5.3% P275P (CCG→CCA hybA ← hydrogenase 2 4Fe‑4S ferredoxin‑type component
RA 3,142,594 C→A 6.3% E79D (GAG→GAT yqhA ← UPF0114 family putative inner membrane protein
RA 3,147,091 C→T 5.2% A57V (GCA→GTA)  yghB → general envelope maintenance protein; DedA family inner membrane protein
RA 3,158,037 C→T 6.7% K432K (AAG→AAA parC ← DNA topoisomerase IV, subunit A
RA 3,173,669 G→T 46.3% A189A (GCG→GCT ygiB → DUF1190 family protein
RA 3,174,009 G→T 5.5% R77L (CGC→CTC)  ygiC → ATP‑Grasp family ATPase
RA 3,182,319 G→T 5.2% pseudogene (1540/2445 nt) yqiG → pseudogene; fimbrial export usher family;putative membrane; Not classified; putative membrane protein
RA 3,211,932 C→A 17.5% V168V (GTG→GTT aer ← fused signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component
RA 3,243,810 C→T 12.0% intergenic (+75/‑111) yqjK → / → yqjF uncharacterized protein/putative quinol oxidase subunit
RA 3,246,908 G→A 15.5% R222R (CGC→CGT yhaJ ← LysR family putative transcriptional regulator
RA 3,247,010 C→A 8.8% P188P (CCG→CCT yhaJ ← LysR family putative transcriptional regulator
RA 3,252,258 C→A 68.7% D251Y (GAT→TAT)  tdcG ← L‑serine dehydratase 3, anaerobic
RA 3,262,048 G→A 5.5% G92D (GGT→GAT)  yhaC → pentapetide repeats‑related protein
RA 3,278,427 C→A 31.4% C128* (TGC→TGA agaC → N‑acetylgalactosamine‑specific enzyme IIC component of PTS
RA 3,293,909 T→A 8.9% Q70L (CAA→CTA)  yhbS ← putative acyl‑CoA transferase
RA 3,302,027 G→T 48.9% S86* (TCG→TAG)  nlpI ← lipoprotein involved in osmotic sensitivity and filamentation
RA 3,314,415 C→A 6.8% P186P (CCG→CCT yhbX ← putative EptAB family phosphoethanolamine transferase, inner membrane protein
RA 3,314,944 G→A 14.4% T10I (ACT→ATT)  yhbX ← putative EptAB family phosphoethanolamine transferase, inner membrane protein
RA 3,337,617 T→A 7.3% I105I (ATT→ATA lptB → lipopolysaccharide export ABC transporter ATP‑binding protein of the LptBFGC export complex
RA 3,346,662 G→T 5.8% R250S (CGC→AGC)  yhcC ← putative Fe‑S oxidoreductase, Radical SAM superfamily protein
RA 3,354,405 C→T 69.4% intergenic (+430/‑130) gltD → / → gltF glutamate synthase, 4Fe‑4S protein, small subunit/periplasmic protein
RA 3,371,372 G→T 19.5% I65I (ATC→ATA rpsI ← 30S ribosomal subunit protein S9
RA 3,373,985 C→A 65.0% intergenic (+37/‑117) yhcB → / → degQ DUF1043 family inner membrane‑anchored protein/serine endoprotease, periplasmic
RA 3,375,260 G→T 61.1% D387Y (GAT→TAT)  degQ → serine endoprotease, periplasmic
RA 3,378,591 G→A 6.1% intergenic (+59/‑306) argR → / → yhcN l‑arginine‑responsive arginine metabolism regulon transcriptional regulator/cadmium and peroxide resistance protein, stress‑induced
RA 3,387,121 C→T 5.8% A833T (GCT→ACT)  yhdP ← DUF3971‑AsmA2 domains protein
RA 3,396,082 G→T 49.8% R204S (CGT→AGT)  csrD ← targeting factor for csrBC sRNA degradation
RA 3,422,390 C→A 8.4% intergenic (‑269/‑205) rrsD ← / → yrdA 16S ribosomal RNA of rrnD operon/bacterial transferase hexapeptide domain protein
RA 3,440,151 G→T 43.3% I31I (ATC→ATA rpsN ← 30S ribosomal subunit protein S14
RA 3,440,444 G→T 66.8% S118S (TCC→TCA rplE ← 50S ribosomal subunit protein L5
RA 3,453,315 C→A 5.2% S47* (TCG→TAG)  gspF → general secretory pathway component, cryptic
RA 3,455,867 C→A 70.3% I55I (ATC→ATA gspJ → putative general secretory pathway component, cryptic
RA 3,461,906 G→A 6.5% T436I (ACT→ATT)  chiA ← periplasmic endochitinase
RA 3,469,146 G→T 5.6% I218I (ATC→ATA yheO ← putative PAS domain‑containing DNA‑binding transcriptional regulator
RA 3,471,921 C→A 7.0% intergenic (‑65/+30) slyD ← / ← yheV FKBP‑type peptidyl prolyl cis‑trans isomerase (rotamase)/DUF2387 family putative metal‑binding protein
RA 3,473,139 G→T 72.6% I276I (ATC→ATA kefB ← potassium:proton antiporter
RA 3,491,629 C→A 8.3% P148Q (CCG→CAG)  cysG → fused siroheme synthase 1,3‑dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase
RA 3,494,195 G→T 8.4% A309A (GCG→GCT frlA → putative fructoselysine transporter
RA 3,494,306 C→A 6.7% F346L (TTC→TTA frlA → putative fructoselysine transporter
RA 3,495,992 G→A 8.5% M98I (ATG→ATA frlC → fructoselysine 3‑epimerase
RA 3,498,239 A→C 6.2% intergenic (+97/+55) frlR → / ← yhfS putative DNA‑binding transcriptional regulator/FNR‑regulated pyridoxal phosphate‑dependent aminotransferase family protein
RA 3,501,910 G→A 6.3% H14Y (CAT→TAT)  php ← phosphotriesterase homology protein
RA 3,502,657 G→T 5.6% I172I (ATC→ATA yhfW ← phosphopentomutase‑related metalloenzyme superfamily protein
RA 3,504,812 C→T 6.2% E298K (GAA→AAA)  yhfZ ← putative DNA‑binding transcriptional regulator
RA 3,516,949 C→A 8.9% F240L (TTC→TTA mrcA → fused penicillin‑binding protein 1a: murein transglycosylase/murein transpeptidase
RA 3,519,657 G→T 100% intergenic (‑149/‑171) nudE ← / → yrfF adenosine nucleotide hydrolase; substrates include Ap3A, Ap2A, ADP‑ribose, NADH/inner membrane protein
RA 3,522,558 G→T 5.2% A177A (GCG→GCT yrfG → GMP/IMP nucleotidase
RA 3,527,522 G→T 5.1% R449L (CGT→CTT)  pck → phosphoenolpyruvate carboxykinase
RA 3,529,524 G→T 7.9% F140L (TTC→TTA ompR ← response regulator in two‑component regulatory system with EnvZ
RA 3,530,481 G→T 14.8% R104L (CGT→CTT)  greB → transcript cleavage factor
RA 3,543,959 G→T 70.1% A625E (GCG→GAG)  malP ← maltodextrin phosphorylase
RA 3,553,566 C→A 6.8% D134Y (GAT→TAT)  glpR ← GlpR DNA‑binding transcriptional repressor
RA 3,555,325 T→C 18.8% intergenic (‑142/‑48) glpE ← / → glpD thiosulfate:cyanide sulfurtransferase (rhodanese)/sn‑glycerol‑3‑phosphate dehydrogenase, aerobic, FAD/NAD(P)‑binding
RA 3,561,574 C→A 68.5% W372L (TGG→TTG)  glgC ← glucose‑1‑phosphate adenylyltransferase
RA 3,572,998 T→A 7.7% Y3F (TAC→TTC)  yhhW ← quercetinase activity in vitro
RA 3,575,020 G→A 5.7% intergenic (+34/‑203) yhhY → / → yhhZ putative acetyltransferase/putative Hcp1 family polymorphic toxin protein; putative colicin‑like DNase/tRNase activity
RA 3,576,072 A→G 7.5% K284E (AAA→GAA)  yhhZ → putative Hcp1 family polymorphic toxin protein; putative colicin‑like DNase/tRNase activity
RA 3,579,422 C→A 5.0% E254D (GAG→GAT ggt ← gamma‑glutamyltranspeptidase
RA 3,609,368 T→A 5.6% F256L (TTT→TTA nikB → nickel transporter subunit
RA 3,618,220 G→A 5.7% M161I (ATG→ATA yhhI → putative transposase
RA 3,622,519 C→A 26.8% R127L (CGA→CTA)  rbbA ← ribosome‑associated ATPase: ATP‑binding protein/ATP‑binding membrane protein
RA 3,634,084 C→T 7.5% intergenic (+179/‑138) uspA → / → dtpB universal stress global response regulator/dipeptide and tripeptide permease B
RA 3,635,421 C→T 7.0% G400G (GGC→GGT dtpB → dipeptide and tripeptide permease B
RA 3,636,207 T→A 12.8% T96S (ACT→TCT)  rsmJ ← 16S rRNA m(2)G1516 methyltransferase, SAM‑dependent
RA 3,640,489 T→A 6.3% V277V (GTT→GTA gor → glutathione oxidoreductase
RA 3,646,542 C→A 8.9% S6I (AGC→ATC)  insH1 ← IS5 transposase and trans‑activator
RA 3,662,801 T→A 6.0% intergenic (‑253/‑151) yhjA ← / → treF putative cytochrome C peroxidase/cytoplasmic trehalase
RA 3,671,771 T→A 8.5% intergenic (‑61/+9) yhjG ← / ← yhjH putative inner membrane‑anchored periplasmic AsmA family protein/cyclic‑di‑GMP phosphodiesterase, FlhDC‑regulated
RA 3,675,614 A→T 5.1% V398V (GTT→GTA dctA ← C4‑dicarboxylic acid, orotate and citrate transporter
RA 3,679,301 T→G 47.4% Q1078P (CAG→CCG)  bcsC ← cellulose synthase subunit
RA 3,679,324 C→A 65.0% M1070I (ATG→ATT bcsC ← cellulose synthase subunit
RA 3,681,219 C→A 21.6% A439S (GCG→TCG)  bcsC ← cellulose synthase subunit
RA 3,698,074 C→A 12.2% M16I (ATG→ATT dppC ← dipeptide/heme transporter
RA 3,703,866 C→A 7.1% intergenic (‑31/+293) eptB ← / ← yhjX KDO phosphoethanolamine transferase, Ca(2+)‑inducible/pyruvate‑inducible inner membrane protein, putative transporter
RA 3,721,469 A→C 6.4% D421E (GAT→GAG xylB ← xylulokinase
RA 3,721,485 T→G 8.2% Y416S (TAC→TCC)  xylB ← xylulokinase
RA 3,738,431 C→A 65.6% P90T (CCA→ACA)  yiaN → 2,3‑diketo‑L‑gulonate TRAP transporter large permease protein
RA 3,751,414 T→G 9.5% H603P (CAT→CCT)  selB ← selenocysteinyl‑tRNA‑specific translation factor
RA 3,774,500 A→T 10.2% intergenic (+123/‑75) lldD → / → trmL L‑lactate dehydrogenase, FMN‑linked/tRNA Leu mC34,mU34 2'‑O‑methyltransferase, SAM‑dependent
RA 3,785,915 G→T 63.8% intergenic (‑4/+271) kbl ← / ← yibB glycine C‑acetyltransferase/YibB family protein, function unknown
RA 3,810,195 C→A 67.4% R54S (CGT→AGT)  yicC → UPF0701 family protein
RA 3,813,962 T→C 7.8% Q190R (CAA→CGA)  ligB ← DNA ligase, NAD(+)‑dependent
RA 3,816,601 A→T 94.2% H281L (CAC→CTC)  spoT → bifunctional (p)ppGpp synthetase II/ guanosine‑3',5'‑bis pyrophosphate 3'‑pyrophosphohydrolase
RA 3,818,010 C→A 66.3% H46N (CAT→AAT)  trmH → tRNA mG18‑2'‑O‑methyltransferase, SAM‑dependent
RA 3,825,702 C→A 71.2% K732N (AAG→AAT yicI ← putative alpha‑glucosidase
RA 3,830,134 A→G 5.9% intergenic (+218/‑179) yicT → / → setC pseudogene/putative arabinose efflux transporter
RA 3,830,311 G→T 47.5% intergenic (+395/‑2) yicT → / → setC pseudogene/putative arabinose efflux transporter
RA 3,837,177 C→T 30.2% intergenic (‑28/‑147) yicO ← / → ade putative adenine permease/cryptic adenine deaminase
RA 3,850,839 G→T 30.0% P309Q (CCG→CAG)  yidJ ← sulfatase/phosphatase superfamily protein
RA 3,853,982 T→A 5.1% F114I (TTT→ATT)  yidL → AraC family putative transcriptional regulator
RA 3,859,994 A→T 6.8% L88L (CTT→CTA ibpB ← heat shock chaperone
RA 3,860,159 C→A 72.1% P33P (CCG→CCT ibpB ← heat shock chaperone
RA 3,868,359 C→A 8.9% A54A (GCG→GCT dgoR ← putative DNA‑binding transcriptional regulator
RA 3,882,760 T→A 6.4% V224E (GTG→GAG)  tnaA → tryptophanase/L‑cysteine desulfhydrase, PLP‑dependent
RA 3,888,527 G→T 23.8% L172L (CTG→CTT chrR → chromate reductase, Class I, flavoprotein
RA 3,897,492 G→T 6.8% P489Q (CCG→CAG)  bglF ← fused beta‑glucoside‑specific PTS enzymes: IIA component/IIB component/IIC component
RA 3,907,094 G→A 30.5% intergenic (‑66/+96) glmS ← / ← glmU L‑glutamine:D‑fructose‑6‑phosphate aminotransferase/fused N‑acetyl glucosamine‑1‑phosphate uridyltransferase/glucosamine‑1‑phosphate acetyl transferase
RA 3,910,894 C→A 69.8% M244I (ATG→ATT atpG ← F1 sector of membrane‑bound ATP synthase, gamma subunit
RA 3,912,648 A→T 8.5% G190G (GGT→GGA atpA ← F1 sector of membrane‑bound ATP synthase, alpha subunit
RA 3,915,397 A→C 7.2% N5K (AAT→AAG atpB ← F0 sector of membrane‑bound ATP synthase, subunit a
RA 3,923,700 G→T 8.6% R252S (CGC→AGC)  ravA ← hexameric AAA+ MoxR family ATPase, putative molecular chaperone
RA 3,930,891 G→T 6.2% D80Y (GAT→TAT)  rbsK → ribokinase
RA 3,960,036 G→A 91.8% R87H (CGC→CAC)  rho → transcription termination factor
RA 3,994,247 A→T 71.0% V57E (GTG→GAG)  yigE ← DUF2233 family protein
RA 4,009,705 G→A 66.2% intergenic (‑176/‑86) ysgA ← / → udp putative carboxymethylenebutenolidase/uridine phosphorylase
RA 4,049,008 A→T 13.3% L231Q (CTG→CAG)  glnL ← sensory histidine kinase in two‑component regulatory system with GlnG
RA 4,056,018 T→A 77.0% F138I (TTC→ATC)  yihN → MFS transporter family protein
RA 4,062,424 G→T 65.3% I71I (ATC→ATA yihQ ← alpha‑glucosidase
RA 4,064,048 T→G 8.0% N357H (AAT→CAT)  yihS ← aldose‑ketose isomerase; D‑mannose isomerase
RA 4,066,133 T→G 75.3% S267R (AGC→CGC)  yihU ← gamma‑hydroxybutyrate dehydrogenase, NADH‑dependent
RA 4,068,208 C→A 76.6% G60G (GGC→GGA yihW → DeoR family putative transcriptional regulator
RA 4,081,000 A→C 6.2% E213D (GAA→GAC yiiG → DUF3829 family lipoprotein
RA 4,094,362 C→A 70.3% W181L (TGG→TTG)  cpxA ← sensory histidine kinase in two‑component regulatory system with CpxR
RA 4,096,163 G→T 6.4% R139L (CGA→CTA)  cpxP → inhibitor of the cpx response; periplasmic adaptor protein
RA 4,097,822 G→T 45.4% E115* (GAA→TAA)  pfkA → 6‑phosphofructokinase I
RA 4,127,022 T→G 63.4% E188D (GAA→GAC yijF ← DUF1287 family protein
RA 4,142,369 A→T 13.5% Y220N (TAC→AAC)  ppc ← phosphoenolpyruvate carboxylase
RA 4,143,375 A→G 5.3% intergenic (‑349/+249) ppc ← / ← argE phosphoenolpyruvate carboxylase/acetylornithine deacetylase
RA 4,158,250 A→C 12.5% intergenic (+122/‑50) rrsB → / → gltT 16S ribosomal RNA of rrnB operon/tRNA‑Glu
RA 4,175,869 T→A 12.0% C198S (TGC→AGC)  rpoC → RNA polymerase, beta prime subunit
RA 4,176,823 G→T 47.4% D516Y (GAC→TAC)  rpoC → RNA polymerase, beta prime subunit
RA 4,211,803 G→A 45.4% P205S (CCT→TCT)  arpA ← ankyrin repeat protein
RA 4,213,666 C→A 6.2% intergenic (‑110/‑90) iclR ← / → metH transcriptional repressor/homocysteine‑N5‑methyltetrahydrofolate transmethylase, B12‑dependent
RA 4,230,913 A→T 47.1% W424R (TGG→AGG)  xylE ← D‑xylose transporter
RA 4,259,875 G→T 5.5% S178S (TCG→TCT aphA → acid phosphatase/phosphotransferase, class B, non‑specific
RA 4,271,152 G→T 10.4% M415I (ATG→ATT yjcE → putative cation/proton antiporter
RA 4,273,077 C→A 5.5% intergenic (‑74/+104) yjcF ← / ← actP pentapeptide repeats protein/acetate transporter
RA 4,273,158 A→T 16.6% intergenic (‑155/+23) yjcF ← / ← actP pentapeptide repeats protein/acetate transporter
RA 4,274,926 A→C 7.5% I72M (ATT→ATG yjcH ← DUF485 family inner membrane protein
RA 4,284,083 G→A 5.5% intergenic (+16/‑326) nrfG → / → gltP heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfG/glutamate/aspartate:proton symporter
RA 4,285,857 T→C 5.6% intergenic (+135/+396) gltP → / ← yjcO glutamate/aspartate:proton symporter/Sel1 family TPR‑like repeat protein
RA 4,290,080 G→T 54.6% I256I (ATC→ATA mdtP ← outer membrane factor of efflux pump
RA 4,291,537 G→T 22.4% I453I (ATC→ATA mdtO ← membrane translocase (MDR) of MdtNOP efflux pump, PET family
RA 4,294,039 A→G 7.0% I61T (ATT→ACT)  ytcA ← putative inner membrane DUF1656 family protein; efflux pump associated
RA 4,295,721 A→G 10.9% Y232H (TAC→CAC)  yjcS ← metallo‑beta‑lactamase superfamily protein
RA 4,297,846 C→A 88.4% M150I (ATG→ATT alsE ← allulose‑6‑phosphate 3‑epimerase
RA 4,303,256 G→T 8.7% V30V (GTG→GTT rpiB → ribose 5‑phosphate isomerase B/allose 6‑phosphate isomerase
RA 4,303,614 T→A 44.1% *150R (TGA→AGA)  rpiB → ribose 5‑phosphate isomerase B/allose 6‑phosphate isomerase
RA 4,306,969 T→A 32.7% N23Y (AAC→TAC)  phnM ← ribophosphonate triphosphate hydrolase
RA 4,312,246 C→A 25.8% intergenic (‑7/+14) phnF ← / ← phnE putative DNA‑binding transcriptional regulator of phosphonate uptake and biodegradation/defective phosphonate ABC transporter permease;transport; Transport of small molecules: Anions; membrane channel protein component of Pn transporter; membrane component of ABC superfamily
RA 4,315,765 A→G 5.2% intergenic (‑207/+451) yjdN ← / ← yjdM metalloprotein superfamily protein/zinc‑ribbon family protein
RA 4,356,453 C→A 6.3% P46P (CCG→CCT dcuA ← C4‑dicarboxylate antiporter
RA 4,367,995 G→A 5.2% P256L (CCC→CTC)  ampC ← penicillin‑binding protein; beta‑lactamase, intrinsically weak
RA 4,380,814 C→A 5.5% A171A (GCG→GCT rsgA ← ribosome small subunit‑dependent GTPase A
RA 4,382,806 T→A 24.9% Q360L (CAA→CTA)  queG ← epoxyqueuosine reductase, cobalamine‑stimulated; queosine biosynthesis
RA 4,388,902 G→T 67.6% A558A (GCG→GCT mutL → methyl‑directed mismatch repair protein
RA 4,396,598 A→T 68.9% E43V (GAA→GTA)  rnr → exoribonuclease R, RNase R
RA 4,402,613 G→T 8.0% S137I (AGC→ATC)  yjfM → DUF1190 family protein
RA 4,413,425 G→T 6.8% E255* (GAA→TAA)  ulaE → L‑xylulose 5‑phosphate 3‑epimerase
RA 4,422,157 C→A 8.1% A239A (GCG→GCT ytfF ← DMT transporter family inner membrane protein
RA 4,436,661 C→A 12.5% N911K (AAC→AAA tamB → translocation and assembly module for autotransporter export, inner membrane subunit
RA 4,440,479 C→T 7.5% A234V (GCG→GTG)  ytfQ → galactofuranose binding proteint: periplasmic‑binding component of ABC superfamily
RA 4,458,254 T→A 71.9% V271V (GTT→GTA mgtA → magnesium transporter
RA 4,458,609 G→T 70.4% D390Y (GAT→TAT)  mgtA → magnesium transporter
RA 4,463,946 C→A 8.7% V2V (GTC→GTA bdcR → transcriptional repressor for divergent bdcA
RA 4,464,572 G→T 30.6% intergenic (+38/‑107) bdcR → / → tabA transcriptional repressor for divergent bdcA/biofilm modulator regulated by toxins; DUF386 family protein, cupin superfamily
RA 4,466,937 A→C 5.4% T562P (ACT→CCT)  yjgL → uncharacterized protein
RA 4,469,550 G→A 40.9% A2T (GCT→ACT)  yjgN → DUF898 family inner membrane protein
RA 4,470,017 G→A 69.6% M157I (ATG→ATA yjgN → DUF898 family inner membrane protein
RA 4,483,103 G→A 6.8% G22G (GGC→GGT idnO ← 5‑keto‑D‑gluconate‑5‑reductase
RA 4,489,542 A→T 19.1% pseudogene (810/942 nt) yjgX ← pseudogene fragment
RA 4,491,549 G→A 5.2% intergenic (+143/+371) yjgZ → / ← insG uncharacterized protein/IS4 transposase
RA 4,495,002 C→A 6.0% F376L (TTC→TTA yjhB → putative transporter
RA 4,502,777 G→A 10.0% N150N (AAC→AAT fecC ← iron‑dicitrate transporter subunit
RA 4,510,428 G→T 15.0% intergenic (‑287/+60) yjhU ← / ← yjhF putative DNA‑binding transcriptional regulator; KpLE2 phage‑like element/putative transporter
RA 4,511,877 G→A 22.9% intergenic (‑40/+67) yjhF ← / ← yjhG putative transporter/putative dehydratase
RA 4,512,693 T→A 68.4% K407* (AAG→TAG)  yjhG ← putative dehydratase
RA 4,521,271 C→A 5.8% A66A (GCG→GCT sgcX ← putative endoglucanase with Zn‑dependent exopeptidase domain
RA 4,525,234 G→A 65.3% pseudogene (415/1029 nt) yjhR → pseudogene, helicase family; putative frameshift suppressor
RA 4,529,866 C→T 6.7% intergenic (‑548/‑908) nanC ← / → fimB N‑acetylnuraminic acid outer membrane channel protein/tyrosine recombinase/inversion of on/off regulator of fimA
RA 4,531,143 A→T 70.2% I124F (ATT→TTT)  fimB → tyrosine recombinase/inversion of on/off regulator of fimA
RA 4,546,084 G→A 5.6% H18H (CAC→CAT yjiC ← uncharacterized protein
RA 4,556,296 C→T 29.3% Q256Q (CAG→CAA yjiN ← zinc‑type alcohol dehydrogenase‑like protein
RA 4,562,043 C→A 66.6% intergenic (+311/‑188) yjiS → / → yjiT DUF1127 family protein/pseudogene
RA 4,579,917 C→A 7.3% A394S (GCG→TCG)  yjiY ← putative transporter
RA 4,582,677 G→T 5.1% E402* (GAA→TAA)  tsr → methyl‑accepting chemotaxis protein I, serine sensor receptor
RA 4,584,381 G→T 72.5% I53I (ATC→ATA yjjL ← L‑galactonate transporter
RA 4,588,471 G→A 5.4% A263V (GCG→GTG)  opgB ← phosphoglycerol transferases I and II
RA 4,596,108 T→A 6.3% intergenic (‑5/+24) leuP ← / ← leuQ tRNA‑Leu/tRNA‑Leu
RA 4,601,014 T→C 21.7% intergenic (+194/‑199) prfC → / → osmY peptide chain release factor RF‑3/periplasmic protein
RA 4,604,616 C→A 5.6% G249C (GGC→TGC)  yjjW ← putative pyruvate formate lyase activating enzyme
RA 4,618,167 G→A 6.2% E346K (GAG→AAG)  nadR → trifunctional protein: nicotinamide mononucleotide adenylyltransferase, ribosylnicotinamide kinase, transcriptional repressor
RA 4,626,235 G→T 21.2% E138* (GAA→TAA)  creB → response regulator in two‑component regulatory system with CreC
RA 4,629,507 C→A 5.1% R206L (CGC→CTC)  arcA ← response regulator in two‑component regulatory system with ArcB or CpxA
RA 4,629,622 C→A 12.7% A168S (GCC→TCC)  arcA ← response regulator in two‑component regulatory system with ArcB or CpxA

Unassigned missing coverage evidence
   seq id start end size ←reads reads→ gene description
* * ÷ CP009273 373826 375137 1312 213 [207] [210] 213 frmA–[frmR] frmA,[frmR]
* * ÷ CP009273 4100602 4101519 918 213 [208] [208] 215 [cdh]–tpiA [cdh],tpiA

Unassigned new junction evidence
  seq id position reads (cov) reads (cov) score skew freq annotation gene product
* ? CP009273 360104 =255 (0.850)359 (1.200) 155/278 NT 58.5% intergenic (‑38/+557) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 360286 NA (NA)intergenic (‑220/+375) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
* ? CP009273 = 360278NA (NA)8298 (29.400)
+TTAATTAA
196/262 NT 96.4% intergenic (‑212/+383) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 361823 333 (1.110)coding (831/834 nt) mhpR mhp operon transcriptional activator
* ? CP009273 360652 =307 (1.020)7606 (38.080)
+46 bp
185/186 NT 97.7% intergenic (‑586/+9) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 1317577 233 (0.780)coding (101/882 nt) yciV PHP domain protein
* ? CP009273 376716 =NA (NA)72 (0.240) 48/278 NT 21.2% intergenic (‑1/‑91) yaiX/insC1 pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase/IS2 repressor TnpA
?CP009273 = 386403 267 (0.890)pseudogene (697/1458 nt) yaiT pseudogene, autotransporter family;putative structure; Not classified; interrupted by IS3; putative flagellin structural protein
* ? CP009273 376716 =NA (NA)255 (0.850) 131/278 NT 86.1% intergenic (‑1/‑91) yaiX/insC1 pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase/IS2 repressor TnpA
?CP009273 566411 = 41 (0.140)coding (63/552 nt) ybcL inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family
* ? CP009273 = 378046NA (NA)66 (0.220) 43/278 NT 19.5% intergenic (+11/+1) insD1/yaiX IS2 transposase TnpB/pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase
?CP009273 386399 = 273 (0.910)pseudogene (693/1458 nt) yaiT pseudogene, autotransporter family;putative structure; Not classified; interrupted by IS3; putative flagellin structural protein
* ? CP009273 = 378046NA (NA)269 (0.900) 141/278 NT 88.8% intergenic (+11/+1) insD1/yaiX IS2 transposase TnpB/pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase
?CP009273 = 566415 34 (0.110)coding (67/552 nt) ybcL inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family
* ? CP009273 1203246 =21 (0.070)253 (0.960) 135/246 NT 92.6% coding (290/630 nt) stfP e14 prophage; uncharacterized protein
?CP009273 1205075 = 22 (0.080)pseudogene (1/501 nt) stfE pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
* ? CP009273 1203252 =25 (0.080)5 (0.020)
+C
5/276 NT 16.5% coding (296/630 nt) stfP e14 prophage; uncharacterized protein
?CP009273 1205070 = 26 (0.090)pseudogene (6/501 nt) stfE pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
* ? CP009273 = 120326126 (0.090)239 (0.900) 131/246 NT 91.4% coding (305/630 nt) stfP e14 prophage; uncharacterized protein
?CP009273 = 1205058 22 (0.080)pseudogene (18/501 nt) stfE pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
* ? CP009273 1635219 =102 (0.350)213 (0.720) 111/274 NT 67.6% intergenic (‑377/+377) essQ/cspB Qin prophage; putative S lysis protein/Qin prophage; cold shock protein
?CP009273 = 2063752 NA (NA)noncoding (1/1331 nt) IS2 repeat region
* ? CP009273 = 163522399 (0.330)206 (0.690) 112/278 NT 67.5% intergenic (‑381/+373) essQ/cspB Qin prophage; putative S lysis protein/Qin prophage; cold shock protein
?CP009273 = 1645805 NA (NA)intergenic (+11/‑3) insD1/intQ IS2 transposase TnpB;IS, phage, Tn; Transposon‑related functions; extrachromosomal; transposon related/pseudogene, Qin prophage; phage integrase family;Phage or Prophage Related
* ? CP009273 3904514 =256 (0.850)14 (0.050) 12/278 NT 5.2% coding (372/1041 nt) pstS periplasmic phosphate binding protein, high‑affinity
?CP009273 4487998 = NA (NA)intergenic (+241/‑91) intB/insC1 pseudogene, integrase homology;IS, phage, Tn; Phage‑related functions and prophages; KpLE2 phage‑like element; P4‑like integrase/IS2 repressor TnpA
* ? CP009273 4532499 =268 (0.890)22 (0.080) 20/260 NT 8.1% intergenic (+49/‑433) fimE/fimA tyrosine recombinase/inversion of on/off regulator of fimA/major type 1 subunit fimbrin (pilin)
?CP009273 4532813 = 250 (0.890)intergenic (+363/‑119) fimE/fimA tyrosine recombinase/inversion of on/off regulator of fimA/major type 1 subunit fimbrin (pilin)
* ? CP009273 = 4532507277 (0.920)21 (0.070) 17/260 NT 7.6% intergenic (+57/‑425) fimE/fimA tyrosine recombinase/inversion of on/off regulator of fimA/major type 1 subunit fimbrin (pilin)
?CP009273 = 4532803 250 (0.890)intergenic (+353/‑129) fimE/fimA tyrosine recombinase/inversion of on/off regulator of fimA/major type 1 subunit fimbrin (pilin)