breseq  version 0.35.4  revision f352f80f4bc9
mutation predictions | marginal predictions | summary statistics | genome diff | command line log

Predicted mutations
evidence position mutation freq annotation gene description
RA 958 G→T 17.7% D208Y (GAC→TAC)  thrA → Bifunctional aspartokinase/homoserine dehydrogenase 1
RA 2,577 C→A 47.4% G747G (GGC→GGA thrA → Bifunctional aspartokinase/homoserine dehydrogenase 1
RA 3,618 C→A 16.1% P273Q (CCG→CAG)  thrB → homoserine kinase
RA 5,144 G→A 100% intergenic (+124/‑90) thrC → / → yaaX L‑threonine synthase/DUF2502 family putative periplasmic protein
RA 10,444 G→T 100% F17L (TTC→TTA satP ← succinate‑acetate transporter
RA 12,901 G→A 100% D247N (GAT→AAT)  dnaK → chaperone Hsp70, with co‑chaperone DnaJ
RA 22,030 G→T 10.7% P208P (CCG→CCT ribF → bifunctional riboflavin kinase/FAD synthetase
RA 25,546 G→T 94.1% D114Y (GAC→TAC)  lspA → prolipoprotein signal peptidase (signal peptidase II)
RA 29,139 G→T 100% G256C (GGT→TGT)  dapB → dihydrodipicolinate reductase
RA 31,710 C→A 6.7% I298I (ATC→ATA carB → carbamoyl‑phosphate synthase large subunit
RA 32,632 G→T 42.2% V606F (GTC→TTC)  carB → carbamoyl‑phosphate synthase large subunit
RA 32,659 C→A 5.9% R615S (CGC→AGC)  carB → carbamoyl‑phosphate synthase large subunit
RA 32,802 C→A 9.8% I662I (ATC→ATA carB → carbamoyl‑phosphate synthase large subunit
RA 33,567 C→A 7.4% V917V (GTC→GTA carB → carbamoyl‑phosphate synthase large subunit
RA 42,079 G→A 18.9% intergenic (‑148/‑324) caiT ← / → fixA putative transporter/anaerobic carnitine reduction putative electron transfer flavoprotein subunit
RA 42,150 G→A 93.3% intergenic (‑219/‑253) caiT ← / → fixA putative transporter/anaerobic carnitine reduction putative electron transfer flavoprotein subunit
RA 42,415 A→C 19.1% T5P (ACT→CCT)  fixA → anaerobic carnitine reduction putative electron transfer flavoprotein subunit
RA 47,857 C→A 10.6% S30* (TCG→TAG)  kefC → potassium:proton antiporter
RA 49,029 A→C 10.0% S421R (AGC→CGC)  kefC → potassium:proton antiporter
RA 49,840 G→T 100% A6A (GCG→GCT folA → dihydrofolate reductase
RA 54,392 G→T 5.9% A104E (GCG→GAG)  surA ← peptidyl‑prolyl cis‑trans isomerase (PPIase)
RA 54,887 G→T 7.8% N741K (AAC→AAA lptD ← LPS assembly OM complex LptDE, beta‑barrel component
RA 55,590 G→T 100% T507K (ACG→AAG)  lptD ← LPS assembly OM complex LptDE, beta‑barrel component
RA 56,677 G→T 100% R145S (CGC→AGC)  lptD ← LPS assembly OM complex LptDE, beta‑barrel component
RA 69,367 C→A 23.8% M16I (ATG→ATT thiQ ← thiamine, thiamine pyrophosphate ABC transporter ATPase; ThiBPQ thiamine, thiamine pyrophosphate importer
RA 69,546 A→T 38.9% F488Y (TTC→TAC)  thiP ← thiamine, thiamine pyrophosphate ABC transporter permease; ThiBPQ thiamine, thiamine pyrophosphate importer
RA 70,465 G→T 16.9% H182N (CAT→AAT)  thiP ← thiamine, thiamine pyrophosphate ABC transporter permease; ThiBPQ thiamine, thiamine pyrophosphate importer
RA 70,744 G→T 7.0% R89R (CGG→AGG)  thiP ← thiamine, thiamine pyrophosphate ABC transporter permease; ThiBPQ thiamine, thiamine pyrophosphate importer
RA 76,821 G→T 38.6% G177G (GGC→GGA leuC ← 3‑isopropylmalate dehydratase large subunit
RA 80,123 C→T 91.6% G25S (GGC→AGC)  leuL ← leu operon leader peptide
RA 81,562 C→A 100% I236I (ATC→ATA leuO → global transcription factor
RA 82,037 C→T 6.4% intergenic (+238/‑80) leuO → / → ilvI global transcription factor/acetolactate synthase 3 large subunit
RA 84,481 G→A 18.1% intergenic (+146/‑34) ilvH → / → cra acetolactate synthase 3, small subunit, valine‑sensitive/transcriptional repressor‑activator for carbon metabolism
RA 86,729 G→T 15.3% R50L (CGT→CTT)  rsmH → 16S rRNA m(4)C1402 methyltransferase, SAM‑dependent
RA 90,252 G→T 18.6% A200A (GCG→GCT murE → UDP‑N‑acetylmuramoyl‑L‑alanyl‑D‑glutamate:meso‑ diaminopimelate ligase
RA 93,391 G→T 87.5% T301T (ACG→ACT mraY → phospho‑N‑acetylmuramoyl‑pentapeptide transferase
RA 95,873 G→T 45.5% S328S (TCG→TCT ftsW → lipid II flippase; integral membrane protein involved in stabilizing FstZ ring during cell division
RA 97,521 C→A 100% A90A (GCC→GCA murC → UDP‑N‑acetylmuramate:L‑alanine ligase
RA 102,736 C→A 6.4% I315I (ATC→ATA ftsZ → GTP‑binding tubulin‑like cell division protein
RA 102,769 G→T 6.2% V326V (GTG→GTT ftsZ → GTP‑binding tubulin‑like cell division protein
RA 103,467 G→T 100% D142Y (GAT→TAT)  lpxC → UDP‑3‑O‑acyl N‑acetylglucosamine deacetylase
RA 104,561 G→T 100% A124S (GCG→TCG)  secM → regulator of secA translation
RA 107,298 C→A 6.9% R845S (CGT→AGT)  secA → preprotein translocase subunit, ATPase
RA 108,648 Δ1 bp 100% coding (439/744 nt) zapD ← FtsZ stabilizer
RA 110,883 A→T 12.3% Y318F (TAC→TTC)  guaC → GMP reductase
RA 112,729 G→T 19.4% D286E (GAC→GAA hofB ← T2SE secretion family protein; P‑loop ATPase superfamily protein
RA 114,825 G→A 20.1% S103F (TCC→TTC)  nadC ← quinolinate phosphoribosyltransferase
RA 116,052 G→T 12.6% L95L (CTG→CTT ampE → ampicillin resistance inner membrane protein; putative signaling protein in beta‑lactamase regulation
RA 118,526 C→T 14.1% intergenic (‑488/‑53) aroP ← / → pdhR aromatic amino acid transporter/pyruvate dehydrogenase complex repressor; autorepressor
RA 118,873 G→T 100% D99Y (GAC→TAC)  pdhR → pyruvate dehydrogenase complex repressor; autorepressor
RA 119,467 G→T 42.5% intergenic (+124/‑37) pdhR → / → aceE pyruvate dehydrogenase complex repressor; autorepressor/pyruvate dehydrogenase, decarboxylase component E1, thiamine triphosphate‑binding
RA 120,313 C→A 20.0% T270T (ACC→ACA aceE → pyruvate dehydrogenase, decarboxylase component E1, thiamine triphosphate‑binding
RA 121,004 C→A 7.1% R501S (CGT→AGT)  aceE → pyruvate dehydrogenase, decarboxylase component E1, thiamine triphosphate‑binding
RA 122,790 G→T 16.2% A203A (GCG→GCT aceF → pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2
RA 124,371 C→A 47.3% intergenic (+297/‑28) aceF → / → lpd pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2/lipoamide dehydrogenase, E3 component is part of three enzyme complexes
RA 126,667 G→T 20.4% R361R (CGG→AGG)  yacH ← uncharacterized protein
RA 134,028 G→T 92.2% A153A (GCG→GCT cueO → multicopper oxidase (laccase)
RA 137,071 G→T 6.5% I214I (ATC→ATA gcd ← glucose dehydrogenase
RA 142,460 T→A 100% F298Y (TTC→TAC)  yadE → putative polysaccharide deacetylase lipoprotein
RA 146,343 G→T 55.5% T366T (ACC→ACA yadC ← putative fimbrial‑like adhesin protein
RA 149,697 G→T 13.1% I739I (ATC→ATA htrE ← putative outer membrane usher protein
RA 151,620 C→A 54.2% K98N (AAG→AAT htrE ← putative outer membrane usher protein
RA 153,472 G→T 94.8% intergenic (‑102/+268) yadN ← / ← folK putative fimbrial‑like adhesin protein/2‑amino‑4‑hydroxy‑6‑hydroxymethyldihyropteridine pyrophosphokinase
RA 158,287 C→A 100% D78Y (GAC→TAC)  ligT ← 2'‑5' RNA ligase
RA 159,121 A→T 10.6% E177V (GAA→GTA)  hrpB → putative ATP‑dependent helicase
RA 161,068 A→C 23.5% intergenic (+47/‑149) hrpB → / → mrcB putative ATP‑dependent helicase/fused glycosyl transferase and transpeptidase
RA 162,905 G→T 14.4% V563V (GTG→GTT mrcB → fused glycosyl transferase and transpeptidase
RA 163,686 C→A 38.5% Q824K (CAG→AAG)  mrcB → fused glycosyl transferase and transpeptidase
RA 166,662 C→A 6.8% S133* (TCG→TAG)  fhuC → iron‑hydroxamate transporter subunit
RA 167,106 G→T 7.5% A15A (GCG→GCT fhuD → iron‑hydroxamate transporter subunit
RA 176,783 G→T 89.6% D354Y (GAT→TAT)  dgt → deoxyguanosine triphosphate triphosphohydrolase
RA 177,895 A→T 11.9% A175A (GCA→GCT degP → serine endoprotease (protease Do), membrane‑associated
RA 183,669 C→A 13.7% R490L (CGC→CTC)  glnD ← uridylyltransferase
RA 186,159 A→G 9.3% intergenic (‑166/‑40) map ← / → tff methionine aminopeptidase/novel sRNA, function unknown
RA 194,124 C→A 40.2% I364I (ATC→ATA rseP → inner membrane zinc RIP metalloprotease; RpoE activator, by degrading RseA; cleaved signal peptide endoprotease
RA 201,962 A→T 86.9% D117V (GAT→GTT)  dnaE → DNA polymerase III alpha subunit
RA 207,709 C→A 5.5% A515E (GCA→GAA)  ldcC → lysine decarboxylase 2, constitutive
RA 212,284 G→T 6.4% A177S (GCA→TCA)  nlpE → lipoprotein involved with copper homeostasis and adhesion
RA 214,084 G→T 7.4% G393G (GGC→GGA proS ← prolyl‑tRNA synthetase
RA 217,887 C→T 5.1% W74* (TGG→TGA metI ← DL‑methionine transporter subunit
RA 217,932 A→C 89.6% I59M (ATT→ATG metI ← DL‑methionine transporter subunit
RA 219,803 A→T 16.6% T162S (ACG→TCG)  gmhB → D,D‑heptose 1,7‑bisphosphate phosphatase
RA 225,620 C→A 10.8% intergenic (+129/‑34) aspU → / → dkgB tRNA‑Asp/2,5‑diketo‑D‑gluconate reductase B
RA 229,707 G→T 18.8% R246S (CGT→AGT)  mltD ← putative membrane‑bound lytic murein transglycosylase D
RA 230,579 C→T 100% E231K (GAA→AAA)  gloB ← hydroxyacylglutathione hydrolase
RA 232,860 G→T 100% D103Y (GAT→TAT)  dnaQ → DNA polymerase III epsilon subunit
RA 236,234 A→T 90.7% V148E (GTG→GAG)  yafV ← putative NAD(P)‑binding C‑N hydrolase family amidase
RA 238,195 G→T 100% V532V (GTC→GTA fadE ← acyl coenzyme A dehydrogenase
RA 239,590 C→A 6.1% M67I (ATG→ATT fadE ← acyl coenzyme A dehydrogenase
RA 241,156 A→T 10.8% K115* (AAA→TAA)  yafJ → putative amidotransfease
RA 247,048 G→T 5.6% pseudogene (490/756 nt) lafU → pseudogene, lateral flagellar motor protein fragment
RA 248,447 C→T 6.4% intergenic (+7/‑45) dinB → / → yafN DNA polymerase IV/antitoxin of the YafO‑YafN toxin‑antitoxin system
RA 248,486 C→A 9.2% intergenic (+46/‑6) dinB → / → yafN DNA polymerase IV/antitoxin of the YafO‑YafN toxin‑antitoxin system
RA 250,909 A→T 6.0% L432Q (CTG→CAG)  pepD ← aminoacyl‑histidine dipeptidase (peptidase D)
RA 253,769 C→T 13.1% V252V (GTC→GTT frsA → fermentation‑respiration switch protein; PTS Enzyme IIA(Glc)‑binding protein; pNP‑butyrate esterase activity
RA 255,284 G→T 32.2% N176K (AAC→AAA phoE ← outer membrane phosphoporin protein E
RA 255,487 A→T 6.9% S109T (TCT→ACT)  phoE ← outer membrane phosphoporin protein E
RA 258,054 G→T 50.2% G281C (GGC→TGC)  proA → gamma‑glutamylphosphate reductase
RA 259,494 G→T 6.2% C75* (TGC→TGA yafW ← CP4‑6 prophage; antitoxin of the YkfI‑YafW toxin‑antitoxin system
RA 262,114 C→A 89.9% D51Y (GAT→TAT)  yafY ← lipoprotein, inner membrane; overproduction stimulates degP expression; CP4‑6 prophage
RA 263,270 C→A 14.9% V149V (GTG→GTT yafZ ← CP4‑6 prophage; conserved protein
RA 274,735 A→T 93.1% pseudogene (138/348 nt) afuB ← pseudogene, CP4‑6 prophage; ABC transporter permease family;Phage or Prophage Related
RA 279,334 C→A 23.3% I141I (ATC→ATA yagF → CP4‑6 prophage; dehydratase family protein
RA 279,800 G→T 5.8% E297* (GAA→TAA)  yagF → CP4‑6 prophage; dehydratase family protein
RA 284,904 C→A 13.0% intergenic (‑31/+108) yagI ← / ← argF CP4‑6 prophage; putative DNA‑binding transcriptional regulator/ornithine carbamoyltransferase 2, chain F; CP4‑6 prophage
RA 285,869 G→T 17.2% L50I (CTC→ATC)  argF ← ornithine carbamoyltransferase 2, chain F; CP4‑6 prophage
RA 290,012 C→T 5.8% D167N (GAT→AAT)  yagM ← CP4‑6 prophage; uncharacterized protein
RA 291,453 A→T 16.2% L452* (TTA→TAA)  intF ← CP4‑6 prophage; putative phage integrase
RA 294,344 C→A 6.0% V32L (GTA→TTA)  paoD ← moco insertion factor for PaoABC aldehyde oxidoreductase
RA 294,929 C→A 7.6% E573* (GAA→TAA)  paoC ← PaoABC aldehyde oxidoreductase, Moco‑containing subunit
RA 296,308 G→T 13.9% A113E (GCG→GAG)  paoC ← PaoABC aldehyde oxidoreductase, Moco‑containing subunit
RA 298,201 C→A 5.5% L28L (CTG→CTT paoA ← PaoABC aldehyde oxidoreductase, 2Fe‑2S subunit
RA 299,623 C→A 13.9% G91* (GGA→TGA)  ykgJ ← UPF0153 cysteine cluster protein
RA 300,770 C→A 6.1% V49V (GTG→GTT ecpE ← ECP production pilus chaperone
RA 302,428 G→T 17.6% P34Q (CCG→CAG)  ecpD ← polymerized tip adhesin of ECP fibers
RA 307,479 G→A 5.3% intergenic (‑432/‑344) ecpR ← / → ykgL putative transcriptional regulator for the ecp operon/uncharacterized protein
RA 310,697 G→T 5.5% pseudogene (630/872 nt) eaeH → pseudogene, attaching and effacing protein homology;factor; Not classified
RA 312,532 G→A 100% pseudogene (349/684 nt) ykgA ← pseudogene, AraC family;putative regulator; Not classified; putative ARAC‑type regulatory protein
RA 314,408 A→G 44.0% D435D (GAT→GAC rclA ← reactive chlorine stress species (RCS) resistance protein; pyridine nucleotide‑dependent disulfide oxidoreductase family
RA 314,566 C→A 5.9% D383Y (GAT→TAT)  rclA ← reactive chlorine stress species (RCS) resistance protein; pyridine nucleotide‑dependent disulfide oxidoreductase family
RA 317,205 G→A 94.4% intergenic (+413/‑114) rclR → / → ykgE reactive chlorine species (RCS)‑specific activator of the rcl genes/cysteine‑rich LutA family protein; putative electron transport chain YkgEFG component
RA 319,024 C→A 5.1% R326S (CGC→AGC)  ykgF → ferridoxin‑like LutB family protein; putative electron transport chain YkgEFG component
RA 319,381 G→T 6.2% D445Y (GAC→TAC)  ykgF → ferridoxin‑like LutB family protein; putative electron transport chain YkgEFG component
RA 319,825 G→T 13.3% E119D (GAG→GAT ykgG → LutC family protein; putative electron transport chain YkgEFG component
RA 319,890 C→A 5.2% S141* (TCG→TAG)  ykgG → LutC family protein; putative electron transport chain YkgEFG component
RA 320,920 G→A 100% S52S (AGC→AGT ykgH ← putative inner membrane protein
RA 321,223 C→A 100% intergenic (‑148/+65) ykgH ← / ← betA putative inner membrane protein/choline dehydrogenase, a flavoprotein
RA 332,599 G→T 8.3% A37A (GCG→GCT yahF → putative NAD(P)‑binding succinyl‑CoA synthase
RA 335,247 C→A 7.6% N404K (AAC→AAA yahG → DUF1116 family protein
RA 337,720 G→T 7.4% E295D (GAG→GAT yahJ → putative metallo‑dependent hydrolase domain deaminase
RA 344,800 G→T 100% E136D (GAG→GAT prpB → 2‑methylisocitrate lyase
RA 353,486 A→T 7.6% intergenic (+321/+16) codA → / ← cynR cytosine/isoguanine deaminase/transcriptional activator of cyn operon; autorepressor
RA 353,489 C→T 5.8% intergenic (+324/+13) codA → / ← cynR cytosine/isoguanine deaminase/transcriptional activator of cyn operon; autorepressor
RA 360,317 C→A 42.9% intergenic (‑251/+344) lacZ ← / ← lacI pseudogene, truncated/DNA‑binding transcriptional repressor
RA 360,752 A→G 100% V331A (GTG→GCG)  lacI ← DNA‑binding transcriptional repressor
RA 361,667 T→A 21.0% Q26L (CAG→CTG)  lacI ← DNA‑binding transcriptional repressor
RA 361,806 G→A 100% intergenic (‑63/+14) lacI ← / ← mhpR DNA‑binding transcriptional repressor/mhp operon transcriptional activator
RA 362,159 G→T 94.0% I165I (ATC→ATA mhpR ← mhp operon transcriptional activator
RA 364,561 G→T 5.6% D18Y (GAC→TAC)  mhpB → 2,3‑dihydroxyphenylpropionate 1,2‑dioxygenase
RA 367,252 C→A 8.5% pseudogene (39/348 nt) mhpC → pseudogene, IS30 insertion
RA 372,091 C→A 6.6% R393R (CGG→AGG)  mhpT → 3‑hydroxyphenylpropionic transporter
RA 372,581 G→T 6.4% A118A (GCG→GCT yaiL → DUF2058 family protein
RA 380,236 C→A 20.0% intergenic (‑164/‑452) yaiS ← / → tauA putative PIG‑L family deacetylase/taurine transporter subunit
RA 385,485 C→T 17.6% intergenic (‑302/‑222) hemB ← / → yaiT 5‑aminolevulinate dehydratase (porphobilinogen synthase)/pseudogene, autotransporter family;putative structure; Not classified; interrupted by IS3; putative flagellin structural protein
RA 385,815 G→T 92.7% pseudogene (109/1458 nt) yaiT → pseudogene, autotransporter family;putative structure; Not classified; interrupted by IS3; putative flagellin structural protein
RA 390,551 T→G 8.9% L197R (CTG→CGG)  yaiV → putative transcriptional regulator
RA 395,951 G→T 47.9% V143V (GTC→GTA ddlA ← D‑alanine‑D‑alanine ligase A
RA 396,883 A→G 100% Q14Q (CAA→CAG iraP → anti‑RssB factor, RpoS stabilzer during Pi starvation; anti‑adapter protein
RA 397,959 G→A 94.3% A253T (GCG→ACG)  phoA → bacterial alkaline phosphatase
RA 399,531 G→T 15.0% A125S (GCG→TCG)  yaiC → diguanylate cyclase, cellulose regualtor
RA 400,594 G→T 8.5% V169V (GTC→GTA proC ← pyrroline‑5‑carboxylate reductase, NAD(P)‑binding
RA 402,340 G→T 100% V160V (GTG→GTT aroL → shikimate kinase II
RA 405,970 C→A 42.6% T124K (ACG→AAG)  mak → manno(fructo)kinase
RA 406,002 G→T 12.6% G135C (GGC→TGC)  mak → manno(fructo)kinase
RA 406,075 C→A 100% P159Q (CCG→CAG)  mak → manno(fructo)kinase
RA 409,063 A→T 11.0% L716* (TTG→TAG)  sbcC ← exonuclease, dsDNA, ATP‑dependent
RA 411,027 G→T 100% L61L (CTC→CTA sbcC ← exonuclease, dsDNA, ATP‑dependent
RA 421,799 C→A 94.6% I69I (ATC→ATA tgt → tRNA‑guanine transglycosylase
RA 425,143 G→T 90.8% T61T (ACG→ACT secF → SecYEG protein translocase auxillary subunit
RA 432,092 G→A 9.1% K16K (AAG→AAA pgpA → phosphatidylglycerophosphatase A
RA 432,762 G→T 5.3% P277Q (CCG→CAG)  yajO ← 2‑carboxybenzaldehyde reductase
RA 433,551 G→T 100% S14Y (TCC→TAC)  yajO ← 2‑carboxybenzaldehyde reductase
RA 433,738 A→C 51.4% intergenic (‑147/+33) yajO ← / ← dxs 2‑carboxybenzaldehyde reductase/1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring
RA 434,663 A→C 100% I324S (ATC→AGC)  dxs ← 1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring
RA 435,336 G→T 93.8% Q100K (CAG→AAG)  dxs ← 1‑deoxyxylulose‑5‑phosphate synthase, thiamine triphosphate‑binding, FAD‑requiring
RA 435,862 A→T 9.4% T232T (ACT→ACA ispA ← geranyltranstransferase
RA 437,371 G→T 11.5% D123Y (GAT→TAT)  thiI → tRNA s(4)U8 sulfurtransferase
RA 437,672 T→A 100% V223E (GTG→GAG)  thiI → tRNA s(4)U8 sulfurtransferase
RA 444,489 G→A 100% R537C (CGT→TGT)  cyoB ← cytochrome o ubiquinol oxidase subunit I
RA 446,369 T→G 90.3% Q233P (CAG→CCG)  cyoA ← cytochrome o ubiquinol oxidase subunit II
RA 450,290 G→A 100% intergenic (+45/‑299) bolA → / → tig stationary‑phase morphogene, transcriptional repressor for mreB; also regulator for dacA, dacC, and ampC/peptidyl‑prolyl cis/trans isomerase (trigger factor)
RA 450,766 G→T 6.1% A60S (GCG→TCG)  tig → peptidyl‑prolyl cis/trans isomerase (trigger factor)
RA 456,298 T→A 100% L652Q (CTG→CAG)  lon → DNA‑binding ATP‑dependent protease La
RA 456,588 G→T 100% D749Y (GAC→TAC)  lon → DNA‑binding ATP‑dependent protease La
RA 458,644 C→A 14.3% P425Q (CCG→CAG)  ppiD → periplasmic folding chaperone, has an inactive PPIase domain
RA 458,681 C→A 14.5% I437I (ATC→ATA ppiD → periplasmic folding chaperone, has an inactive PPIase domain
RA 461,499 G→T 6.7% R424S (CGC→AGC)  ybaE ← putative ABC superfamily transporter periplasmic‑binding protein
RA 463,179 C→A 7.2% I104I (ATC→ATA cof → thiamine pyrimidine pyrophosphate hydrolase; HMP‑PP phosphatase
RA 463,263 A→T 10.4% I132I (ATA→ATT cof → thiamine pyrimidine pyrophosphate hydrolase; HMP‑PP phosphatase
RA 466,184 G→T 6.1% M31I (ATG→ATT mdlB → putative multidrug transporter subunit of ABC superfamily, ATP‑binding component
RA 474,138 G→T 94.2% intergenic (‑65/+99) ylaB ← / ← ylaC putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase/DUF1449 family inner membrane protein
RA 475,805 C→A 100% A120A (GCG→GCT tomB ← Hha toxicity attenuator; conjugation‑related protein
RA 477,267 G→T 5.4% Q865K (CAG→AAG)  acrB ← multidrug efflux system protein
RA 478,523 G→T 5.4% A446E (GCG→GAG)  acrB ← multidrug efflux system protein
RA 479,122 G→T 17.1% F246L (TTC→TTA acrB ← multidrug efflux system protein
RA 479,244 C→A 100% A206S (GCC→TCC)  acrB ← multidrug efflux system protein
RA 480,820 C→T 100% D86N (GAC→AAC)  acrA ← multidrug efflux system
RA 481,667 G→A 100% A151T (GCG→ACG)  acrR → transcriptional repressor
RA 486,494 C→A 5.8% R53S (CGC→AGC)  ybaN → DUF454 family inner membrane protein
RA 487,486 G→T 10.5% intergenic (+67/‑62) apt → / → dnaX adenine phosphoribosyltransferase/DNA polymerase III/DNA elongation factor III, tau and gamma subunits
RA 495,020 T→A 6.7% E137V (GAA→GTA)  aes ← acetyl esterase
RA 498,579 G→T 42.7% A39E (GCG→GAG)  ybaL ← inner membrane putative NAD(P)‑binding transporter
RA 500,178 G→T 45.3% intergenic (‑26/‑192) fsr ← / → ushA putative fosmidomycin efflux system protein/bifunctional UDP‑sugar hydrolase/5'‑nucleotidase
RA 500,613 G→T 15.2% G82C (GGT→TGT)  ushA → bifunctional UDP‑sugar hydrolase/5'‑nucleotidase
RA 509,737 G→A 91.3% E97K (GAG→AAG)  cueR → copper‑responsive regulon transcriptional regulator
RA 520,254 G→T 9.9% R513L (CGC→CTC)  rhsD → Rhs family putative polymorphic toxin
RA 520,873 A→T 13.5% A719A (GCA→GCT rhsD → Rhs family putative polymorphic toxin
RA 521,011 G→T 21.1% E765D (GAG→GAT rhsD → Rhs family putative polymorphic toxin
RA 522,859 T→G 19.7% S1381R (AGT→AGG rhsD → Rhs family putative polymorphic toxin
RA 523,413 G→T 18.4% pseudogene (6/708 nt) rhsH → pseudogene, Rhs familly protein
RA 524,334:1 +T 100% pseudogene (239/491 nt) ybbD → pseudogene
RA 524,496 T→G 8.6% pseudogene (401/491 nt) ybbD → pseudogene
RA 530,466 C→A 100% F365L (TTC→TTA gcl → glyoxylate carboligase
RA 531,158 G→T 6.0% intergenic (+5/‑8) gcl → / → hyi glyoxylate carboligase/hydroxypyruvate isomerase
RA 531,226 T→A 8.7% F21I (TTT→ATT)  hyi → hydroxypyruvate isomerase
RA 538,153 A→C 14.3% E270D (GAA→GAC glxK → glycerate kinase II
RA 538,400 G→T 45.4% E353* (GAA→TAA)  glxK → glycerate kinase II
RA 542,200 Δ1 bp 100% coding (65/1668 nt) fdrA → putative NAD(P)‑binding acyl‑CoA synthetase
RA 544,142 G→T 36.2% P110P (CCG→CCT ylbE → NO‑induced DUF1116 protein
RA 545,542 G→T 6.1% D154Y (GAC→TAC)  ylbF → putative anaerobic allantoin catabolic oxamate carbamoyltransferase; DUF2877 family protein
RA 546,491 G→T 100% V199V (GTG→GTT ybcF → putative carbonate kinase
RA 549,397 G→T 100% intergenic (‑1/+2) lpxH ← / ← ppiB UDP‑2,3‑diacylglucosamine pyrophosphohydrolase/peptidyl‑prolyl cis‑trans isomerase B (rotamase B)
RA 551,499 G→T 6.0% R171S (CGC→AGC)  ybcI ← DUF457 family inner membrane protein
RA 557,592 G→T 93.1% D814Y (GAC→TAC)  sfmD → putative outer membrane export usher protein
RA 557,784 G→T 17.8% intergenic (+28/‑8) sfmD → / → sfmH putative outer membrane export usher protein/FimA homolog
RA 566,710 G→T 46.9% G121V (GGC→GTC)  ybcL → inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family
RA 571,745 G→T 43.2% pseudogene (537/1040 nt) nmpC ← DLP12 prophage; truncated outer membrane porin (pseudogene);IS, phage, Tn; Phage or Prophage Related; outer membrane porin protein; locus of qsr prophage
RA 572,129 T→G 40.1% pseudogene (153/1040 nt) nmpC ← DLP12 prophage; truncated outer membrane porin (pseudogene);IS, phage, Tn; Phage or Prophage Related; outer membrane porin protein; locus of qsr prophage
RA 576,653 G→T 46.4% A122S (GCA→TCA)  nohD → DLP12 prophage; DNA packaging protein
RA 576,998 G→T 100% pseudogene (189/309 nt) aaaD → pseudogene; DLP12 prophage; tail fiber assembly protein family;Phage or Prophage Related
RA 580,102 G→T 41.2% intergenic (+216/+34) appY → / ← ompT global transcriptional activator; DLP12 prophage/DLP12 prophage; outer membrane protease VII (outer membrane protein 3b)
RA 580,558 C→A 11.2% D178Y (GAT→TAT)  ompT ← DLP12 prophage; outer membrane protease VII (outer membrane protein 3b)
RA 581,203 A→T 100% intergenic (‑114/‑310) ompT ← / → pauD DLP12 prophage; outer membrane protease VII (outer membrane protein 3b)/tRNA‑OTHER
RA 583,341 T→G 94.8% S33R (AGT→CGT)  ybcH ← PRK09936 family protein
RA 596,812 G→T 10.2% M881I (ATG→ATT cusA → copper/silver efflux system, membrane component
RA 598,618 G→T 11.2% E402* (GAA→TAA)  pheP → phenylalanine transporter
RA 602,195 C→A 7.4% T215T (ACG→ACT ybdK ← weak gamma‑glutamyl:cysteine ligase
RA 603,207 G→T 15.4% noncoding (18/59 nt) sokE → sRNA at remnant mokE/hokE locus
RA 604,929 A→T 16.7% C203S (TGC→AGC)  entD ← phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex
RA 607,931 G→A 100% S7F (TCC→TTC)  fepA ← iron‑enterobactin outer membrane transporter
RA 614,511 G→T 9.9% D268Y (GAT→TAT)  fepE → regulator of length of O‑antigen component of lipopolysaccharide chains
RA 615,143 C→A 12.4% T171T (ACG→ACT fepC ← iron‑enterobactin transporter subunit
RA 619,048 C→A 93.4% A307S (GCC→TCC)  fepB ← iron‑enterobactin transporter subunit
RA 623,812 G→T 11.5% V221V (GTG→GTT entB → isochorismatase
RA 624,669 G→T 9.1% T221T (ACG→ACT entA → 2,3‑dihydro‑2,3‑dihydroxybenzoate dehydrogenase
RA 625,174 G→T 6.2% intergenic (+5/‑176) entH → / → cstA enterobactin synthesis proofreading thioesterase/carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 625,364 G→T 94.9% G5G (GGG→GGT cstA → carbon starvation protein involved in peptide utilization; APC peptide transporter family protein
RA 629,276 A→T 19.9% K79* (AAA→TAA)  ybdL → methionine aminotransferase, PLP‑dependent
RA 630,742 C→A 41.3% E31* (GAA→TAA)  ybdM ← Spo0J family protein, ParB‑like nuclease domain
RA 632,286 C→A 46.9% E263D (GAG→GAT ybdO ← putative DNA‑binding transcriptional regulator
RA 633,925 G→A 5.4% I35I (ATC→ATT dsbG ← thiol:disulfide interchange protein, periplasmic
RA 638,587 G→T 5.7% E348D (GAG→GAT ybdR → putative Zn‑dependent NAD(P)‑binding oxidoreductase
RA 639,231 G→A 100% L65F (CTT→TTT)  rnk ← regulator of nucleoside diphosphate kinase
RA 647,234 C→T 100% E27K (GAA→AAA)  citC ← [citrate [pro‑3S]‑lyase] ligase
RA 647,422 G→T 100% intergenic (‑110/‑269) citC ← / → citA [citrate [pro‑3S]‑lyase] ligase/sensory histidine kinase in two‑component regulatory system with CitB
RA 647,509 T→C 100% intergenic (‑197/‑182) citC ← / → citA [citrate [pro‑3S]‑lyase] ligase/sensory histidine kinase in two‑component regulatory system with CitB
RA 648,056 C→A 100% F122L (TTC→TTA citA → sensory histidine kinase in two‑component regulatory system with CitB
RA 652,442 T→A 15.0% Y144N (TAC→AAC)  pagP → phospholipid:lipid A palmitoyltransferase
RA 652,597 C→T 100% intergenic (+24/‑151) pagP → / → cspE phospholipid:lipid A palmitoyltransferase/constitutive cold shock family transcription antitermination protein; negative regulator of cspA transcription; RNA melting protein; ssDNA‑binding protein
RA 652,865 Δ1 bp 94.6% coding (118/210 nt) cspE → constitutive cold shock family transcription antitermination protein; negative regulator of cspA transcription; RNA melting protein; ssDNA‑binding protein
RA 659,689 G→T 5.8% R320S (CGC→AGC)  rlpA ← septal ring protein, suppressor of prc, minor lipoprotein
RA 662,108 A→T 100% V522V (GTT→GTA mrdA ← transpeptidase involved in peptidoglycan synthesis (penicillin‑binding protein 2)
RA 662,631 C→A 100% R348L (CGC→CTC)  mrdA ← transpeptidase involved in peptidoglycan synthesis (penicillin‑binding protein 2)
RA 667,348 G→T 100% Q99K (CAG→AAG)  lptE ← LPS assembly OM complex LptDE, lipoprotein component
RA 667,397 G→T 40.4% I82I (ATC→ATA lptE ← LPS assembly OM complex LptDE, lipoprotein component
RA 667,899 C→A 5.8% D781Y (GAT→TAT)  leuS ← leucyl‑tRNA synthetase
RA 672,142 T→A 89.2% intergenic (‑139/‑25) ybeQ ← / → ybeR Sel1 family TPR‑like repeat protein/uncharacterized protein
RA 677,557 C→A 9.5% K431N (AAG→AAT hscC ← Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription
RA 678,325 G→T 40.3% G175G (GGC→GGA hscC ← Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription
RA 679,765 G→T 48.6% S35Y (TCT→TAT)  rihA ← ribonucleoside hydrolase 1
RA 693,739 G→T 89.0% H299N (CAC→AAC)  asnB ← asparagine synthetase B
RA 702,869 G→T 13.0% D441Y (GAT→TAT)  glnS → glutamyl‑tRNA synthetase
RA 705,588 C→A 100% intergenic (+16/+68) chiQ → / ← fur chitosugar‑induced verified lipoprotein/ferric iron uptake regulon transcriptional repressor; autorepressor
RA 706,097 A→C 91.4% T2T (ACT→ACG
*29G (TGA→GGA) 
fur ←
uof ←
ferric iron uptake regulon transcriptional repressor; autorepressor
ryhB‑regulated fur leader peptide
RA 706,479 C→A 19.7% R148L (CGT→CTT)  fldA ← flavodoxin 1
RA 709,827 G→T 43.7% D272Y (GAT→TAT)  pgm → phosphoglucomutase
RA 710,187 A→T 5.3% S392C (AGT→TGT)  pgm → phosphoglucomutase
RA 720,173 G→T 9.3% A88E (GCG→GAG)  kdpC ← potassium translocating ATPase, subunit C
RA 721,412 T→A 16.1% N361Y (AAC→TAC)  kdpB ← potassium translocating ATPase, subunit B
RA 723,859 G→T 8.6% V110V (GTC→GTA kdpA ← potassium translocating ATPase, subunit A
RA 724,813 A→T 100% intergenic (+17/‑226) ybfA → / → rhsC DUF2517 family protein/Rhs family putative polymorphic toxin
RA 725,650 G→T 5.0% P204P (CCG→CCT rhsC → Rhs family putative polymorphic toxin
RA 729,456 G→A 92.6% R75R (AGG→AGA ybfB → putative membrane protein
RA 732,349 G→T 5.5% pseudogene (69/1137 nt) ybfL → pseudogene, DDE domain transposase family;putative factor; Not classified; putative receptor protein
RA 732,416 G→A 5.4% pseudogene (136/1137 nt) ybfL → pseudogene, DDE domain transposase family;putative factor; Not classified; putative receptor protein
RA 732,494 G→T 90.3% pseudogene (214/1137 nt) ybfL → pseudogene, DDE domain transposase family;putative factor; Not classified; putative receptor protein
RA 732,752 C→T 16.0% pseudogene (472/1137 nt) ybfL → pseudogene, DDE domain transposase family;putative factor; Not classified; putative receptor protein
RA 733,541 G→A 18.2% intergenic (+124/‑7) ybfL → / → ybfD pseudogene, DDE domain transposase family;putative factor; Not classified; putative receptor protein/H repeat‑associated putative transposase
RA 737,635 G→T 5.8% G126G (GGC→GGA dtpD ← dipeptide and tripeptide permease D
RA 738,124:1 +T 46.0% intergenic (‑112/‑159) dtpD ← / → ybgI dipeptide and tripeptide permease D/NIF3 family metal‑binding protein
RA 743,797 G→T 9.4% R214R (CGC→CGA ybgO ← putative fimbrial protein
RA 745,420 C→A 14.9% G736C (GGT→TGT)  ybgQ ← putative outer membrane protein
RA 748,707 A→T 7.4% I406I (ATT→ATA gltA ← citrate synthase
RA 753,549 G→T 7.3% Q135H (CAG→CAT sdhB → succinate dehydrogenase, FeS subunit
RA 754,572 G→T 100% E137D (GAG→GAT sucA → 2‑oxoglutarate decarboxylase, thiamine triphosphate‑binding
RA 759,000 C→A 100% F177L (TTC→TTA sucC → succinyl‑CoA synthetase, beta subunit
RA 761,420 C→T 12.0% intergenic (‑89/‑20) mngR ← / → mngA Transcriptional repressor for the mannosyl‑D‑glycerate catabolic operon/fused 2‑O‑a‑mannosyl‑D‑glycerate specific PTS enzymes: IIA component/IIB component/IIC component
RA 767,694 G→A 50.0% E261K (GAA→AAA)  cydA → cytochrome d terminal oxidase, subunit I
RA 769,421 C→A 13.6% I308I (ATC→ATA cydB → cytochrome d terminal oxidase, subunit II
RA 772,664 A→C 9.6% K289N (AAA→AAC tolA → membrane anchored protein in TolA‑TolQ‑TolR complex
RA 776,049 C→A 17.6% noncoding (40/76 nt) lysT → tRNA‑Lys
RA 777,175 A→T 11.7% intergenic (+67/‑366) lysQ → / → nadA tRNA‑Lys/quinolinate synthase, subunit A
RA 784,094 G→T 5.2% A67E (GCG→GAG)  galM ← aldose 1‑epimerase; type‑1 mutarotase
RA 784,482 G→T 13.0% I318I (ATC→ATA galK ← galactokinase
RA 788,902 G→T 94.5% R115S (CGT→AGT)  modF ← fused molybdate transporter subunits of ABC superfamily: ATP‑binding components
RA 792,957 C→A 38.9% V316V (GTC→GTA modC → molybdate transporter subunit
RA 796,821 G→T 39.3% A203S (GCT→TCT)  ybhH → putative PrpF family isomerase
RA 800,488 G→T 91.6% V510V (GTG→GTT ybhJ → putative hydratase
RA 800,779 G→T 100% E607D (GAG→GAT ybhJ → putative hydratase
RA 809,212 G→T 5.6% M77I (ATG→ATT uvrB → excinulease of nucleotide excision repair, DNA damage recognition component
RA 815,168 C→A 15.1% R140R (CGG→AGG)  moaE → molybdopterin synthase, large subunit
RA 816,292 A→T 5.4% H15L (CAC→CTC)  ybhM → UPF0005 family inner membrane protein
RA 816,302 G→T 8.6% R18S (AGG→AGT ybhM → UPF0005 family inner membrane protein
RA 818,362 G→T 16.6% G278G (GGC→GGA clsB ← cardiolipin synthase 2
RA 825,641 G→T 37.4% A153A (GCC→GCA ybiH ← DUF1956 domain‑containing tetR family putative transcriptional regulator
RA 828,374 G→T 100% V11V (GTC→GTA ybiA ← DUF1768 family protein
RA 829,009 G→T 10.0% D162Y (GAT→TAT)  dinG → ATP‑dependent DNA helicase
RA 832,445 G→T 94.8% P213P (CCG→CCT ybiC → putative dehydrogenase
RA 837,698 G→A 49.5% intergenic (‑186/‑90) mcbA ← / → rlmF colanic acid mucoidy stimulation protein/23S rRNA m(6)A1618 methyltransferase, SAM‑dependent
RA 837,716 G→T 5.8% intergenic (‑204/‑72) mcbA ← / → rlmF colanic acid mucoidy stimulation protein/23S rRNA m(6)A1618 methyltransferase, SAM‑dependent
RA 842,041 C→A 6.7% E179* (GAA→TAA)  glnP ← glutamine transporter subunit
RA 843,299 C→A 100% W54C (TGG→TGT glnH ← glutamine transporter subunit
RA 858,992 C→T 17.9% intergenic (‑25/‑106) ybiY ← / → fsaA putative pyruvate formate lyase activating enzyme/fructose‑6‑phosphate aldolase 1
RA 860,669 G→T 12.6% I384I (ATC→ATA moeA ← molybdopterin molybdenumtransferase; molybdopterin biosynthesis protein
RA 862,017 G→T 11.5% intergenic (‑197/‑7) moeA ← / → iaaA molybdopterin molybdenumtransferase; molybdopterin biosynthesis protein/Isoaspartyl peptidase
RA 868,500 A→T 7.9% S22S (TCA→TCT yliE → putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 876,395 G→T 5.7% M71I (ATG→ATT dacC → D‑alanyl‑D‑alanine carboxypeptidase (penicillin‑binding protein 6a)
RA 876,447 G→A 100% D89N (GAT→AAT)  dacC → D‑alanyl‑D‑alanine carboxypeptidase (penicillin‑binding protein 6a)
RA 876,738 G→T 14.8% D186Y (GAT→TAT)  dacC → D‑alanyl‑D‑alanine carboxypeptidase (penicillin‑binding protein 6a)
RA 879,085 G→T 100% intergenic (‑241/‑44) ybjG ← / → mdfA undecaprenyl pyrophosphate phosphatase/multidrug efflux system protein
RA 890,555 G→T 43.5% D37Y (GAT→TAT)  potG → putrescine transporter subunit: ATP‑binding component of ABC superfamily
RA 898,457 G→T 52.7% intergenic (‑13/+5) artI ← / ← artP arginine transporter subunit/arginine transporter subunit
RA 911,375 G→T 42.4% F43L (TTC→TTA aqpZ ← aquaporin Z
RA 912,614 G→T 40.9% R229L (CGA→CTA)  ybjD → putative OLD family ATP‑dependent endonuclease; DUF2813 family protein
RA 920,396 G→T 6.4% A559A (GCG→GCT clpA → ATPase and specificity subunit of ClpA‑ClpP ATP‑dependent serine protease, chaperone activity
RA 925,160 G→T 93.4% S420* (TCA→TAA)  cydD ← fused glutathione, cysteine exporter subunits of ABC superfamily: membrane component/ATP‑binding component
RA 943,573 G→T 100% A297S (GCC→TCC)  ycaM → putative transporter
RA 954,765 C→A 46.2% G166G (GGC→GGA aroA → 5‑enolpyruvylshikimate‑3‑phosphate synthetase
RA 955,568 A→T 94.6% intergenic (+17/‑152) aroA → / → ycaL 5‑enolpyruvylshikimate‑3‑phosphate synthetase/putative peptidase‑related chaperone
RA 968,415 G→T 100% S148* (TCG→TAG)  ycbC ← DUF218 superfamily protein
RA 992,767 C→A 6.1% D68Y (GAT→TAT)  ssuE ← NAD(P)H‑dependent FMN reductase
RA 997,673 A→T 8.6% T137T (ACA→ACT elfG → putative fimbrial‑like adhesin protein
RA 997,965 G→T 92.1% D235Y (GAT→TAT)  elfG → putative fimbrial‑like adhesin protein
RA 1,000,841 G→T 6.3% A206A (GCG→GCT pyrD → dihydro‑orotate oxidase, FMN‑linked
RA 1,003,597 G→T 8.7% D100Y (GAC→TAC)  rlmL → fused 23S rRNA m(2)G2445 and m(7)G2069 methyltransferase, SAM‑dependent
RA 1,011,409 C→A 43.2% *173L (TGA→TTA)  fabA ← beta‑hydroxydecanoyl thioester dehydrase
RA 1,017,626 G→T 37.0% R572S (CGT→AGT)  yccS ← putative transporter, FUSC superfamily inner membrane protein, tandem domains
RA 1,024,387 C→A 12.4% D347Y (GAT→TAT)  rlmI ← 23S rRNA m(5)C1962 methyltransferase, SAM‑dependent
RA 1,024,703 G→T 92.7% G241G (GGC→GGA rlmI ← 23S rRNA m(5)C1962 methyltransferase, SAM‑dependent
RA 1,037,576 G→T 7.4% G697G (GGC→GGA etk ← tyrosine‑protein kinase, role in O‑antigen capsule formation
RA 1,038,316 G→T 6.3% R451S (CGT→AGT)  etk ← tyrosine‑protein kinase, role in O‑antigen capsule formation
RA 1,041,662 G→T 10.5% F580L (TTC→TTA gfcD ← putative O‑antigen capsule production periplasmic protein
RA 1,045,280 G→T 10.2% intergenic (‑80/‑9) gfcA ← / → insA O‑antigen capsule production threonine‑rich inner membrane protein/IS1 repressor TnpA
RA 1,045,471 G→T 39.9% M61I (ATG→ATT insA → IS1 repressor TnpA
RA 1,048,928 C→A 91.5% E903* (GAA→TAA)  torS ← hybrid sensory histidine kinase in two‑component regulatory system with TorR
RA 1,049,407 G→T 93.7% T743K (ACG→AAG)  torS ← hybrid sensory histidine kinase in two‑component regulatory system with TorR
RA 1,055,132 G→T 7.3% E141* (GAA→TAA)  torA → trimethylamine N‑oxide (TMAO) reductase I, catalytic subunit
RA 1,055,617 A→T 8.3% A302A (GCA→GCT torA → trimethylamine N‑oxide (TMAO) reductase I, catalytic subunit
RA 1,063,736 T→C 45.9% intergenic (+26/+231) ymdF → / ← rutG KGG family protein/pyrimidine permease
RA 1,068,091 G→T 44.0% Q77K (CAG→AAG)  rutB ← ureidoacrylate amidohydrolase
RA 1,073,863 G→T 20.8% S159* (TCG→TAG)  putA ← fused DNA‑binding transcriptional regulator/proline dehydrogenase/pyrroline‑5‑carboxylate dehydrogenase
RA 1,077,911 A→C 100% K71N (AAA→AAC efeO → inactive ferrous ion transporter EfeUOB
RA 1,079,951 G→T 7.4% D374Y (GAT→TAT)  efeB → deferrrochelatase, periplasmic
RA 1,080,620 A→T 5.8% K58I (AAA→ATA)  phoH → ATP‑binding protein; putative PhoH family P‑loop ATPase
RA 1,081,099 G→T 10.7% D218Y (GAT→TAT)  phoH → ATP‑binding protein; putative PhoH family P‑loop ATPase
RA 1,083,443 G→T 92.2% S624* (TCG→TAG)  pgaB ← poly‑beta‑1,6‑N‑acetyl‑D‑glucosamine (PGA) N‑deacetylase outer membrane export lipoprotein
RA 1,084,103 A→T 94.8% L404* (TTA→TAA)  pgaB ← poly‑beta‑1,6‑N‑acetyl‑D‑glucosamine (PGA) N‑deacetylase outer membrane export lipoprotein
RA 1,087,360 G→T 47.8% P129Q (CCG→CAG)  pgaA ← biofilm adhesin polysaccharide PGA secretin; OM porin; poly‑beta‑1,6‑N‑acetyl‑D‑glucosamine export protein
RA 1,088,734 G→T 5.6% V135F (GTT→TTT)  ycdT → diguanylate cyclase, membrane‑anchored
RA 1,099,378 A→C 14.0% intergenic (‑726/‑29) csgD ← / → csgB csgBAC operon transcriptional regulator/curlin nucleator protein, minor subunit in curli complex
RA 1,104,639 C→A 6.3% intergenic (‑242/‑152) opgC ← / → opgG osmoregulated periplasmic glucan succinylation membrane protein/osmoregulated periplasmic glucan (OPG) biosynthesis periplasmic protein
RA 1,105,607 G→T 31.7% D273Y (GAC→TAC)  opgG → osmoregulated periplasmic glucan (OPG) biosynthesis periplasmic protein
RA 1,116,964 A→G 100% intergenic (‑21/+53) dinI ← / ← pyrC DNA damage‑inducible protein I/dihydro‑orotase
RA 1,118,841 A→T 8.7% intergenic (‑112/+22) yceB ← / ← grxB lipoprotein, DUF1439 family/glutaredoxin 2 (Grx2)
RA 1,132,098 G→T 43.0% M123I (ATG→ATT flgI → putative flagellar basal body protein
RA 1,139,402 C→A 5.8% R141L (CGC→CTC)  rne ← fused ribonucleaseE: endoribonuclease/RNA‑binding protein/RNA degradosome binding protein
RA 1,147,164 G→A 22.8% D32N (GAC→AAC)  acpP → acyl carrier protein (ACP)
RA 1,150,407 G→T 18.8% P280P (CCG→CCT yceG → septation protein, ampicillin sensitivity
RA 1,151,750 G→T 100% R178L (CGC→CTC)  holB → DNA polymerase III, delta prime subunit
RA 1,152,278 G→T 100% E16* (GAA→TAA)  ycfH → putative DNase
RA 1,153,110 T→A 15.5% intergenic (+80/‑215) ycfH → / → ptsG putative DNase/fused glucose‑specific PTS enzymes: IIB component/IIC component
RA 1,154,905 G→T 18.3% F701L (TTC→TTA fhuE ← ferric‑rhodotorulic acid outer membrane transporter
RA 1,156,310 G→T 7.9% S233* (TCA→TAA)  fhuE ← ferric‑rhodotorulic acid outer membrane transporter
RA 1,169,283 T→A 12.4% A46A (GCA→GCT mfd ← transcription‑repair coupling factor
RA 1,172,212 C→A 13.5% S46S (TCC→TCA lolD → outer membrane‑specific lipoprotein transporter subunit
RA 1,173,073 T→A 16.0% F100I (TTC→ATC)  lolE → lipoprotein‑releasing system transmembrane protein
RA 1,175,193 A→T 5.2% E36V (GAA→GTA)  cobB → deacetylase of acs and cheY, chemotaxis regulator
RA 1,191,676 C→T 85.6% H366H (CAC→CAT icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,688 C→T 84.7% T370T (ACC→ACT icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,701 T→C 82.0% L375L (TTA→CTA) ‡ icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,703 A→G 82.0% L375L (TTA→TTG) ‡ icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,733 C→T 74.5% N385N (AAC→AAT icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,736 G→C 74.5% A386A (GCG→GCC icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,739 A→G 71.8% K387K (AAA→AAG icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,748 C→T 67.5% T390T (ACC→ACT icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,191,760 G→A 50.0% E394E (GAG→GAA icd → e14 prophage; isocitrate dehydrogenase, specific for NADP+
RA 1,193,873 G→T 70.3% intergenic (‑180/‑278) ymfE ← / → lit e14 prophage; putative inner membrane protein/e14 prophage; cell death peptidase, inhibitor of T4 late gene expression
RA 1,196,660 G→T 46.1% intergenic (‑172/‑293) xisE ← / → ymfI e14 prophage; putative excisionase/e14 prophage; uncharacterized protein
RA 1,207,686 T→A 9.4% intergenic (‑227/+473) iraM ← / ← ycgX RpoS stabilzer during Mg starvation, anti‑RssB factor/DUF1398 family protein
RA 1,211,136 T→C 6.3% intergenic (‑205/‑109) bluF ← / → ycgZ anti‑repressor for YcgE, blue light‑responsive; FAD‑binding; has c‑di‑GMP phosphodiesterase‑like EAL domain, but does not degrade c‑di‑GMP/RcsB connector protein for regulation of biofilm and acid‑resistance
RA 1,211,169 C→A 100% intergenic (‑238/‑76) bluF ← / → ycgZ anti‑repressor for YcgE, blue light‑responsive; FAD‑binding; has c‑di‑GMP phosphodiesterase‑like EAL domain, but does not degrade c‑di‑GMP/RcsB connector protein for regulation of biofilm and acid‑resistance
RA 1,215,936 G→T 17.0% pseudogene (880/2648 nt) ycgH → pseudogene; putative ATP‑binding component of a transport system
RA 1,219,533 A→G 100% intergenic (+170/+202) ycgI → / ← minE pseudogene/cell division topological specificity factor
RA 1,220,996 G→T 100% R181R (CGG→AGG)  minC ← cell division inhibitor
RA 1,224,292 G→A 100% D8N (GAT→AAT)  ycgN → UPF0153 family cysteine cluster protein
RA 1,225,922 C→T 13.4% intergenic (‑72/‑301) hlyE ← / → umuD hemolysin E/DNA polymerase V, subunit D
RA 1,226,292 T→A 100% C24S (TGT→AGT)  umuD → DNA polymerase V, subunit D
RA 1,228,033 C→A 11.8% A152S (GCT→TCT)  dsbB ← oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I
RA 1,228,591 G→T 100% intergenic (‑105/+41) dsbB ← / ← nhaB oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I/sodium:proton antiporter
RA 1,240,865 A→T 14.0% K84* (AAA→TAA)  ycgY → uncharacterized protein
RA 1,246,435 T→A 16.5% intergenic (‑141/‑87) dhaK ← / → dhaR dihydroxyacetone kinase, PTS‑dependent, dihydroxyacetone‑binding subunit/dhaKLM operon transcription activator
RA 1,249,227 G→T 7.9% R728S (CGT→AGT)  ycgV ← putative adhesin
RA 1,264,442 G→T 7.9% V274V (GTG→GTT kdsA → 3‑deoxy‑D‑manno‑octulosonate 8‑phosphate synthase
RA 1,268,535 A→T 41.1% S191S (TCA→TCT chaC → cation transport regulator
RA 1,276,723 C→A 17.3% T468T (ACC→ACA narG → nitrate reductase 1, alpha subunit
RA 1,277,786 G→A 100% D823N (GAC→AAC)  narG → nitrate reductase 1, alpha subunit
RA 1,282,421 A→T 10.9% intergenic (+439/+101) narI → / ← rttR nitrate reductase 1, gamma (cytochrome b(NR)) subunit/rtT sRNA, processed from tyrT transcript
RA 1,284,124 C→A 22.0% intergenic (‑44/+6) purU ← / ← ychJ formyltetrahydrofolate hydrolase/UPF0225 family protein
RA 1,285,956 G→T 12.6% A87S (GCC→TCC)  rssB → PcnB‑degradosome interaction factor; response regulator
RA 1,287,881 C→A 12.8% intergenic (+60/+84) galU → / ← hns glucose‑1‑phosphate uridylyltransferase/global DNA‑binding transcriptional dual regulator H‑NS
RA 1,288,669 A→T 88.5% intergenic (‑291/‑314) hns ← / → tdk global DNA‑binding transcriptional dual regulator H‑NS/thymidine kinase/deoxyuridine kinase
RA 1,290,033 G→T 9.3% pseudogene (416/567 nt) insZ ← pseudogene, transposase homolog
RA 1,296,729 C→A 7.0% H431N (CAC→AAC)  oppA → oligopeptide transporter subunit
RA 1,299,742 C→A 24.5% A244A (GCC→GCA oppD → oligopeptide transporter subunit
RA 1,313,458 G→T 6.7% L196L (CTC→CTA trpC ← fused indole‑3‑glycerolphosphate synthetase/N‑(5‑phosphoribosyl)anthranilate isomerase
RA 1,322,140 T→A 100% T159S (ACG→TCG)  btuR ← cob(I)yrinic acid a,c‑diamide adenosyltransferase
RA 1,325,982 G→T 10.2% T226T (ACG→ACT topA → DNA topoisomerase I, omega subunit
RA 1,330,955 G→T 89.3% D290Y (GAT→TAT)  acnA → aconitate hydratase 1
RA 1,332,486 G→T 46.6% R800L (CGA→CTA)  acnA → aconitate hydratase 1
RA 1,333,690 G→T 9.3% S35I (AGT→ATT)  pgpB → phosphatidylglycerophosphatase B
RA 1,335,356 A→T 5.5% H181L (CAT→CTT)  yciM → envelope integrity maintenance protein; EnvC‑interacting protein
RA 1,337,533 G→T 100% A18E (GCA→GAA)  osmB ← lipoprotein
RA 1,340,820 G→T 47.7% I60I (ATC→ATA gmr ← cyclic‑di‑GMP phosphodiesterase; csgD regulator; modulator of Rnase II stability
RA 1,341,061 C→A 19.1% Y3* (TAC→TAA ymiB → uncharacterized protein
RA 1,344,412 G→A 10.3% intergenic (‑48/+96) yciW ← / ← fabI putative oxidoreductase/enoyl‑[acyl‑carrier‑protein] reductase, NADH‑dependent
RA 1,351,022 G→T 7.8% R116S (CGT→AGT)  sapA ← antimicrobial peptide transport ABC transporter periplasmic binding protein
RA 1,358,855 G→T 7.1% G123C (GGC→TGC)  puuB → gamma‑glutamylputrescine oxidoreductase
RA 1,365,283 G→T 100% E271* (GAG→TAG)  ycjM → alpha amylase catalytic domain family protein
RA 1,372,069 G→T 45.9% E327D (GAG→GAT ycjS → putative NADH‑binding oxidoreductase
JC JC 1,376,043 IS5 (–) +4 bp 100% pseudogene (10‑13/126 nt) ycjV → pseudogene; putative ATP‑binding component of a transport system
RA 1,377,394 C→T 100% A275A (GCG→GCA ycjW ← LacI family putative transcriptional repressor
RA 1,386,008 G→T 100% Q35K (CAG→AAG)  ycjY ← S9 homolog non‑peptidase family protein
RA 1,388,406 G→T 100% R308L (CGC→CTC)  mppA → murein tripeptide (L‑ala‑gamma‑D‑glutamyl‑meso‑DAP) transporter subunit
RA 1,388,474 G→T 43.1% E331* (GAA→TAA)  mppA → murein tripeptide (L‑ala‑gamma‑D‑glutamyl‑meso‑DAP) transporter subunit
RA 1,389,852 G→T 6.6% R110S (CGC→AGC)  ynaI ← mechanosensitive channel protein, very small conductance
RA 1,420,495 G→A 7.7% intergenic (+156/‑216) ydaY → / → tmpR pseudogene, Rac prophage;Phage or Prophage Related/Rac prophage; pseudogene, tail protein family;Phage or Prophage Related; putative alpha helix protein
RA 1,420,579 G→T 8.1% intergenic (+240/‑132) ydaY → / → tmpR pseudogene, Rac prophage;Phage or Prophage Related/Rac prophage; pseudogene, tail protein family;Phage or Prophage Related; putative alpha helix protein
RA 1,424,234 C→A 100% S310* (TCA→TAA)  stfR → Rac prophage; putative tail fiber protein
JC JC 1,428,894 IS2 (–) +5 bp 100% intergenic (‑413/+317) ynaE ← / ← ttcC cold shock protein, Rac prophage/pseudogene, prophage Rac integration site ttcA duplication;Phage or Prophage Related
RA 1,429,517 G→T 14.5% I120I (ATC→ATA uspF ← stress‑induced protein, ATP‑binding protein
RA 1,430,751 C→A 44.2% G134C (GGT→TGT)  ompN ← outer membrane pore protein N, non‑specific
RA 1,430,873 G→T 9.6% S93* (TCA→TAA)  ompN ← outer membrane pore protein N, non‑specific
RA 1,439,518 C→A 100% S737S (TCC→TCA ydbH → putative membrane‑anchored protein, function unknown
RA 1,441,854 C→A 16.5% R27S (CGT→AGT)  feaB → phenylacetaldehyde dehydrogenase
RA 1,445,781 G→T 22.2% intergenic (‑175/+73) tynA ← / ← paaZ tyramine oxidase, copper‑requiring/fused oxepin‑CoA hydrolase/3‑oxo‑5,6‑dehydrosuberyl‑CoA semialdehyde dehydrogenase
RA 1,448,131 G→A 19.4% intergenic (‑232/‑53) paaZ ← / → paaA fused oxepin‑CoA hydrolase/3‑oxo‑5,6‑dehydrosuberyl‑CoA semialdehyde dehydrogenase/ring 1,2‑phenylacetyl‑CoA epoxidase subunit
RA 1,448,418 C→T 16.4% L79F (CTC→TTC)  paaA → ring 1,2‑phenylacetyl‑CoA epoxidase subunit
RA 1,448,466 C→A 15.6% Q95K (CAA→AAA)  paaA → ring 1,2‑phenylacetyl‑CoA epoxidase subunit
RA 1,451,422 A→T 89.6% T246S (ACG→TCG)  paaE → ring 1,2‑phenylacetyl‑CoA epoxidase, NAD(P)H oxidoreductase component
RA 1,454,724 G→T 94.5% G472C (GGT→TGT)  paaH → 3‑hydroxyadipyl‑CoA dehydrogenase, NAD+‑dependent
RA 1,457,725 G→T 9.5% intergenic (+30/‑71) paaK → / → paaX phenylacetyl‑CoA ligase/transcriptional repressor of phenylacetic acid degradation paa operon, phenylacetyl‑CoA inducer
RA 1,457,811 A→T 35.9% T6S (ACT→TCT)  paaX → transcriptional repressor of phenylacetic acid degradation paa operon, phenylacetyl‑CoA inducer
RA 1,460,593 C→G 5.3% pseudogene (945/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,602 T→C 6.2% pseudogene (954/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,695 T→G 6.2% pseudogene (1047/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,896 C→T 5.8% pseudogene (1248/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,460,986 G→A 6.6% pseudogene (1338/2513 nt) ydbA → pseudogene, autotransporter homolog; interrupted by IS2 and IS30
RA 1,477,570 G→A 16.9% D85N (GAC→AAC)  hrpA → putative ATP‑dependent helicase
RA 1,479,733 G→T 6.5% D806Y (GAT→TAT)  hrpA → putative ATP‑dependent helicase
RA 1,481,236 G→T 48.1% intergenic (+16/‑256) hrpA → / → ydcF putative ATP‑dependent helicase/DUF218 superfamily protein, SAM‑binding
RA 1,489,197 C→T 15.1% K44K (AAG→AAA ydcI ← putative DNA‑binding transcriptional regulator
RA 1,494,358 C→A 12.0% D117Y (GAC→TAC)  ydcK ← uncharacterized protein
RA 1,498,063 C→T 9.0% I30I (ATC→ATT insQ → IS609 transposase B
RA 1,499,199 A→T 53.4% V380E (GTG→GAG)  ydcO ← BenE family inner membrane putative transporter
RA 1,499,759 G→T 15.9% V193V (GTC→GTA ydcO ← BenE family inner membrane putative transporter
RA 1,503,014 G→T 42.6% intergenic (+15/+77) ydcP → / ← yncJ putative peptidase/uncharacterized protein
RA 1,508,681 C→A 12.3% F198L (TTC→TTA ydcU → putative spermidine/putrescine transporter subunit
RA 1,514,858 G→A 8.3% E114K (GAA→AAA)  mcbR → colanic acid and biofilm gene transcriptional regulator, MqsR‑controlled
RA 1,519,349 T→A 100% K297* (AAA→TAA)  ansP ← L‑asparagine transporter
RA 1,525,299 A→T 8.7% pseudogene (457/738 nt) yncI → pseudogene
RA 1,529,506 C→T 14.3% G204S (GGC→AGC)  yddE ← PhzC‑PhzF family protein
RA 1,531,029 G→T 7.7% R180S (CGC→AGC)  narW ← nitrate reductase 2 (NRZ), delta subunit (assembly subunit)
RA 1,531,040 C→A 14.2% R176L (CGC→CTC)  narW ← nitrate reductase 2 (NRZ), delta subunit (assembly subunit)
RA 1,533,556 G→T 17.2% H1098N (CAC→AAC)  narZ ← nitrate reductase 2 (NRZ), alpha subunit
RA 1,534,409 G→T 5.6% V813V (GTC→GTA narZ ← nitrate reductase 2 (NRZ), alpha subunit
RA 1,540,526 C→A 47.1% intergenic (‑241/+19) yddL ← / ← yddG putative lipoprotein;putative membrane; Not classified; putative outer membrane porin protein/aromatic amino acid exporter
RA 1,548,144 G→T 100% intergenic (‑49/+85) adhP ← / ← maeA ethanol‑active dehydrogenase/acetaldehyde‑active reductase/malate dehydrogenase, (decarboxylating, NAD‑requiring) (malic enzyme)
RA 1,548,216 A→T 8.7% intergenic (‑121/+13) adhP ← / ← maeA ethanol‑active dehydrogenase/acetaldehyde‑active reductase/malate dehydrogenase, (decarboxylating, NAD‑requiring) (malic enzyme)
RA 1,551,406 T→A 5.9% E297V (GAG→GTG)  ddpF ← D,D‑dipeptide permease system, ATP‑binding component
RA 1,552,629 C→A 94.5% D216Y (GAT→TAT)  ddpD ← D,D‑dipeptide permease system, ATP‑binding component
RA 1,554,300 G→T 9.3% S296* (TCA→TAA)  ddpB ← D‑ala‑D‑ala transporter subunit
RA 1,554,588 G→T 46.0% A200E (GCG→GAG)  ddpB ← D‑ala‑D‑ala transporter subunit
RA 1,558,685 G→T 7.5% R436S (CGC→AGC)  dosP ← oxygen sensor, c‑di‑GMP phosphodiesterase, heme‑regulated; cold‑ and stationary phase‑induced bioflim regulator
RA 1,561,151 C→A 17.2% D83Y (GAT→TAT)  dosC ← diguanylate cyclase, cold‑ and stationary phase‑induced oxygen‑dependent biofilm regulator
RA 1,563,276 G→T 100% H491N (CAC→AAC)  gadC ← glutamate:gamma‑aminobutyric acid antiporter
RA 1,565,497 G→A 100% S269L (TCG→TTG)  gadB ← glutamate decarboxylase B, PLP‑dependent
RA 1,566,392 A→T 5.3% intergenic (‑90/+272) gadB ← / ← pqqL glutamate decarboxylase B, PLP‑dependent/putative periplasmic M16 family zinc metalloendopeptidase
RA 1,570,428 G→T 5.2% I483I (ATC→ATA yddB ← putative TonB‑dependent outer membrane receptor
RA 1,570,826 C→A 5.6% D351Y (GAC→TAC)  yddB ← putative TonB‑dependent outer membrane receptor
RA 1,572,192 G→T 39.5% L470I (CTT→ATT)  yddA ← putative multidrug transporter subunit of ABC superfamily, membrane component/ATP‑binding component
RA 1,574,523 T→A 7.1% L175F (TTA→TTT ydeM ← putative YdeN‑specific sulfatase‑maturating enzyme
RA 1,575,339 G→T 100% F481L (TTC→TTA ydeN ← putative Ser‑type periplasmic non‑aryl sulfatase
RA 1,576,844 G→A 54.1% intergenic (‑63/+339) ydeN ← / ← ydeO putative Ser‑type periplasmic non‑aryl sulfatase/UV‑inducible global regulator, EvgA‑, GadE‑dependent
RA 1,582,058 A→C 5.4% W166G (TGG→GGG)  ydeR ← putative fimbrial‑like adhesin protein
RA 1,586,871 G→T 26.7% intergenic (‑172/+51) hipB ← / ← yneO antitoxin of HipAB toxin‑antitoxin system/pseudogene, AidA homolog
RA 1,591,853 C→A 49.6% pseudogene (392/5323 nt) yneO ← pseudogene, AidA homolog
RA 1,593,900 G→T 41.7% N189K (AAC→AAA lsrK ← autoinducer‑2 (AI‑2) kinase
RA 1,597,517 T→G 43.3% L81* (TTA→TGA)  lsrC → autoinducer 2 import system permease protein
RA 1,600,589 T→G 38.2% L78R (CTG→CGG)  lsrF → putative autoinducer‑2 (AI‑2) aldolase
RA 1,601,793 C→A 6.5% S64Y (TCT→TAT)  tam → trans‑aconitate methyltransferase
RA 1,603,440 G→A 100% intergenic (‑161/+46) yneE ← / ← uxaB bestrophin family putative inner membrane protein/altronate oxidoreductase, NAD‑dependent
RA 1,604,655 C→A 48.1% E95* (GAA→TAA)  uxaB ← altronate oxidoreductase, NAD‑dependent
RA 1,605,105 C→T 44.8% intergenic (‑168/+59) uxaB ← / ← yneF altronate oxidoreductase, NAD‑dependent/putative membrane‑bound diguanylate cyclase
RA 1,610,766 C→T 16.8% S249S (AGC→AGT yneK → uncharacterized protein
RA 1,611,158 G→T 24.8% intergenic (+23/‑127) yneK → / → ydeA uncharacterized protein/arabinose efflux transporter, arabinose‑inducible
RA 1,614,089 G→T 6.4% E87* (GAG→TAG)  marA → multiple antibiotic resistance transcriptional regulator
RA 1,616,682 T→G 10.5% L365R (CTG→CGG)  ydeE → putative transporter
RA 1,620,961 T→G 100% Q226P (CAA→CCA)  dcp ← dipeptidyl carboxypeptidase II
RA 1,621,470 G→A 13.8% N56N (AAC→AAT dcp ← dipeptidyl carboxypeptidase II
RA 1,628,207 G→A 100% G110E (GGA→GAA)  pinQ → Qin prophage; putative site‑specific recombinase
RA 1,642,135 C→T 6.7% intergenic (‑28/‑56) dicC ← / → dicA Qin prophage; DNA‑binding transcriptional regulator for DicB/Qin prophage; putative regulator for DicB
RA 1,646,412 A→T 20.7% pseudogene (605/1158 nt) intQ → pseudogene, Qin prophage; phage integrase family;Phage or Prophage Related
RA 1,646,993 C→T 47.3% intergenic (+28/+19) intQ → / ← ydfJ pseudogene, Qin prophage; phage integrase family;Phage or Prophage Related/pseudogene, MFS transporter family; interrupted by Qin prophage;Phage or Prophage Related; putative transport protein
RA 1,648,200 G→T 11.3% T400K (ACG→AAG)  rspA ← bifunctional D‑altronate/D‑mannonate dehydratase
RA 1,649,014 C→A 6.3% D129Y (GAT→TAT)  rspA ← bifunctional D‑altronate/D‑mannonate dehydratase
RA 1,653,563 C→A 5.0% S413* (TCG→TAG)  ynfE → putative selenate reductase, periplasmic
RA 1,656,349 G→T 17.6% D513Y (GAT→TAT)  ynfF → S‑ and N‑oxide reductase, A subunit, periplasmic
RA 1,656,621 G→T 9.4% E603D (GAG→GAT ynfF → S‑ and N‑oxide reductase, A subunit, periplasmic
RA 1,659,423 C→T 5.0% intergenic (+46/‑149) dmsD → / → clcB twin‑argninine leader‑binding protein for DmsA and TorA/H(+)/Cl(‑) exchange transporter
RA 1,661,763 C→A 100% P353P (CCG→CCT mlc ← glucosamine anaerobic growth regulon transcriptional repressor; autorepressor
RA 1,667,443 T→G 26.6% T106P (ACC→CCC)  mdtJ ← multidrug efflux system transporter
RA 1,675,777 C→A 46.8% S182* (TCG→TAG)  folM → dihydromonapterin reductase, NADPH‑dependent; dihydrofolate reductase isozyme
RA 1,680,642 C→A 8.9% E68D (GAG→GAT fumC ← fumarate hydratase (fumarase C),aerobic Class II
RA 1,684,105 C→A 9.2% intergenic (+97/‑4) manA → / → ydgA mannose‑6‑phosphate isomerase/DUF945 family protein
RA 1,689,180 T→G 100% E383D (GAA→GAC uidA ← beta‑D‑glucuronidase
RA 1,690,981 G→T 15.0% A110E (GCG→GAG)  uidR ← transcriptional repressor
RA 1,692,221 T→A 5.3% E26V (GAA→GTA)  hdhA ← 7‑alpha‑hydroxysteroid dehydrogenase, NAD‑dependent
RA 1,692,573 C→A 89.2% D289Y (GAT→TAT)  malI ← transcriptional repressor of Mal regulon
RA 1,696,612 A→T 100% E41D (GAA→GAT add → adenosine deaminase
RA 1,697,123 C→A 10.3% R212S (CGT→AGT)  add → adenosine deaminase
RA 1,698,343 C→A 53.2% D75Y (GAT→TAT)  ydgJ ← putative oxidoreductase
RA 1,699,862 T→A 88.5% L119* (TTG→TAG)  ydgK → DUF2569 family inner membrane protein
RA 1,701,260 T→A 16.2% S29T (TCC→ACC)  rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,702,966 T→A 6.5% R597R (CGT→CGA rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,703,015 G→C 5.8% E614Q (GAA→CAA)  rsxC → SoxR iron‑sulfur cluster reduction factor component; putative membrane‑associated NADH oxidoreductase of electron transport complex
RA 1,706,450 C→T 14.1% intergenic (+35/‑576) nth → / → dtpA DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III)/dipeptide and tripeptide permease A
RA 1,706,777 C→A 8.2% intergenic (+362/‑249) nth → / → dtpA DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III)/dipeptide and tripeptide permease A
RA 1,706,994 C→T 12.1% intergenic (+579/‑32) nth → / → dtpA DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III)/dipeptide and tripeptide permease A
RA 1,711,397 C→T 100% R28Q (CGA→CAA)  tyrS ← tyrosyl‑tRNA synthetase
RA 1,718,636 G→T 45.3% L93I (CTT→ATT)  sodC ← superoxide dismutase, Cu, Zn, periplasmic
RA 1,721,644 C→A 40.5% N243K (AAC→AAA nemA → chromate reductase, quinone reductase, FMN‑linked; N‑Ethylmaleimide reductase; old yellow enzyme
RA 1,723,809 G→T 88.5% E156* (GAA→TAA)  lhr → putative ATP‑dependent helicase
RA 1,725,272 G→T 19.3% A643A (GCG→GCT lhr → putative ATP‑dependent helicase
RA 1,732,758 G→T 47.4% D220Y (GAC→TAC)  purR → transcriptional repressor, hypoxanthine‑binding
RA 1,734,392 A→T 11.6% L75F (TTA→TTT ydhC → putative arabinose efflux transporter
RA 1,738,129 C→A 5.2% P139Q (CCG→CAG)  mdtK → multidrug efflux system transporter
RA 1,747,034 C→A 14.7% D352Y (GAT→TAT)  ydhV ← putative oxidoreductase subunit
RA 1,751,673 T→G 45.1% intergenic (+306/‑5) pykF → / → lpp pyruvate kinase I/murein lipoprotein
RA 1,752,893 T→A 5.8% P30P (CCA→CCT ldtE ← murein L,D‑transpeptidase
RA 1,753,293 G→T 48.9% V85V (GTC→GTA sufE ← sulfur acceptor protein
RA 1,754,950 T→A 93.8% I367F (ATT→TTT)  sufD ← component of SufBCD Fe‑S cluster assembly scaffold
RA 1,755,736 C→A 12.6% G105* (GGA→TGA)  sufD ← component of SufBCD Fe‑S cluster assembly scaffold
RA 1,757,647 G→T 5.4% T207K (ACG→AAG)  sufB ← component of SufBCD Fe‑S cluster assembly scaffold
RA 1,764,150 G→T 93.2% D274Y (GAT→TAT)  ydiK → UPF0118 family inner membrane protein
RA 1,764,518 T→A 6.0% intergenic (+75/‑111) ydiK → / → rprA UPF0118 family inner membrane protein/sRNA antisense activator for RpoS translation, Hfq‑dependent
RA 1,767,963 C→A 15.4% P399T (CCT→ACT)  ydiN → MFS transporter superfamily protein
RA 1,768,689 C→A 8.7% S215* (TCA→TAA)  ydiB → quinate/shikimate 5‑dehydrogenase, NAD(P)‑binding
RA 1,769,440 C→A 46.7% A166A (GCC→GCA aroD → 3‑dehydroquinate dehydratase
RA 1,770,281 T→A 100% D146E (GAT→GAA ydiF → putative acetyl‑CoA:acetoacetyl‑CoA transferase: alpha subunit/beta subunit
RA 1,774,858 C→T 45.0% Y67Y (TAC→TAT ydiR → putative electron transfer flavoprotein, FAD‑binding subunit
RA 1,775,744 C→A 18.3% V31V (GTC→GTA ydiS → putative oxidoreductase
RA 1,777,451 C→A 93.5% A55E (GCG→GAG)  fadK → short chain acyl‑CoA synthetase, anaerobic
RA 1,778,803 T→C 9.4% Y506H (TAT→CAT)  fadK → short chain acyl‑CoA synthetase, anaerobic
RA 1,783,091 G→T 7.3% E134* (GAG→TAG)  aroH → 3‑deoxy‑D‑arabino‑heptulosonate‑7‑phosphate synthase, tryptophan repressible
RA 1,798,234 G→T 45.1% pseudogene (460/1476 nt) arpB → pseudogene, ankyrin repeats
RA 1,800,416 C→T 14.6% intergenic (‑76/‑211) ydiY ← / → pfkB acid‑inducible putative outer membrane protein/6‑phosphofructokinase II
RA 1,802,047 G→A 100% intergenic (+100/‑6) ydiZ → / → yniA uncharacterized protein/fructosamine kinase family protein
RA 1,803,109 C→T 92.7% A128T (GCC→ACC)  yniB ← putative inner membrane protein
RA 1,809,895 A→T 5.3% Y591F (TAC→TTC)  katE → catalase HPII, heme d‑containing
RA 1,810,619 G→T 38.7% intergenic (+234/+24) katE → / ← chbG catalase HPII, heme d‑containing/chito‑oligosaccharide deacetylase
RA 1,812,514 C→A 5.9% D82Y (GAT→TAT)  chbF ← phospho‑chitobiase; general 6‑phospho‑beta‑glucosidase activity
RA 1,819,917 C→T 8.7% intergenic (‑35/+295) spy ← / ← astE periplasmic ATP‑independent protein refolding chaperone, stress‑induced/succinylglutamate desuccinylase
RA 1,820,020 C→A 43.9% intergenic (‑138/+192) spy ← / ← astE periplasmic ATP‑independent protein refolding chaperone, stress‑induced/succinylglutamate desuccinylase
RA 1,821,696 A→T 90.7% L274Q (CTG→CAG)  astB ← succinylarginine dihydrolase
RA 1,822,975 C→A 53.8% A339A (GCG→GCT astD ← succinylglutamic semialdehyde dehydrogenase
RA 1,825,763 C→A 91.8% A159A (GCG→GCT astC ← succinylornithine transaminase, PLP‑dependent
RA 1,828,672 A→C 7.6% E100D (GAA→GAC ydjY → putative ferrodoxin‑like lipoprotein
RA 1,832,413 C→A 100% L315L (CTC→CTA ynjC → inner membrane putative ABC superfamily transporter permease
RA 1,833,730 C→A 100% R3S (CGT→AGT)  ynjE → molybdopterin synthase sulfurtransferase
RA 1,849,550 C→A 37.2% G227C (GGC→TGC)  ydjG ← alpha‑Keto reductase, NADH‑dependent; can use methylglyoxal as substrate
RA 1,850,880 C→A 21.9% V102V (GTG→GTT ydjH ← putative kinase
RA 1,860,183 G→T 6.5% R183S (CGC→AGC)  mipA ← scaffolding protein for murein synthesizing machinery
RA 1,862,142 C→A 46.9% I326I (ATC→ATA yeaG → protein kinase, endogenous substrate unidentified; autokinase
RA 1,864,752 C→A 47.6% S37R (AGC→AGA yeaI → putative membrane‑anchored diguanylate cyclase
RA 1,865,000 C→A 7.7% P120Q (CCA→CAA)  yeaI → putative membrane‑anchored diguanylate cyclase
RA 1,865,422 C→A 100% R261R (CGA→AGA)  yeaI → putative membrane‑anchored diguanylate cyclase
RA 1,868,749 A→C 14.1% E47D (GAA→GAC yeaL → UPF0756 family putative inner membrane protein
RA 1,870,743 C→A 6.8% H272N (CAT→AAT)  yeaN → putative transporter
RA 1,872,054 A→T 5.5% E28V (GAG→GTG)  yeaP → diguanylate cyclase
RA 1,872,520 G→T 95.0% P183P (CCG→CCT yeaP → diguanylate cyclase
RA 1,873,569 C→A 16.0% intergenic (‑57/+91) yeaQ ← / ← yoaG UPF0410 family protein/uncharacterized protein
RA 1,874,423 C→A 52.9% L198F (TTG→TTT leuE ← leucine efflux protein
RA 1,875,096 G→T 9.5% intergenic (‑80/+47) leuE ← / ← dmlR leucine efflux protein/transcriptional activator of dmlA
RA 1,879,386 C→A 43.9% I155I (ATC→ATA yeaW → putative YeaWX dioxygenase alpha subunit; 2Fe‑2S cluster
RA 1,880,857 G→T 8.8% M252I (ATG→ATT yeaX → putative YeaWX dioxygenase beta subunit, reductase component
RA 1,885,243 C→A 10.0% T94T (ACG→ACT tsaB ← tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; binding partner and protease for TsaD
RA 1,886,725 G→T 10.5% I256I (ATC→ATA yoaA ← putative ATP‑dependent helicase, DinG family
RA 1,894,208 A→T 6.3% K509* (AAA→TAA)  yoaD → putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase, regulator of cellulose production
RA 1,895,069 C→T 13.5% G258G (GGG→GGA yoaE ← putative membrane protein/conserved protein
RA 1,909,342 T→A 100% E150D (GAA→GAT proQ ← RNA chaperone, putative ProP translation regulator
RA 1,927,856 G→T 5.8% L336I (CTC→ATC)  edd ← 6‑phosphogluconate dehydratase
RA 1,937,083 A→T 41.8% T55T (ACA→ACT znuC → zinc transporter subunit: ATP‑binding component of ABC superfamily
RA 1,940,498 G→T 9.9% intergenic (‑61/‑10) yobI ← / → yebB uncharacterized protein/DUF830 family protein
RA 1,941,921 A→T 14.1% V163E (GTG→GAG)  yebC ← UPF0082 family protein
RA 1,943,414 C→A 17.2% D456Y (GAT→TAT)  aspS ← aspartyl‑tRNA synthetase
RA 1,944,177 C→A 100% L201L (CTG→CTT aspS ← aspartyl‑tRNA synthetase
RA 1,946,006 G→T 43.0% D119Y (GAT→TAT)  yecE → UPF0759 family protein
RA 1,953,876 C→A 7.0% P76P (CCG→CCT yecM ← putative metal‑binding enzyme
RA 1,956,286 G→T 5.9% D20Y (GAT→TAT)  yecT → uncharacterized protein
RA 1,957,975 C→A 13.5% A445S (GCT→TCT)  flhA ← putative flagellar export pore protein
RA 1,959,915 C→A 93.7% P178P (CCG→CCT flhB ← flagellin export apparatus, substrate specificity protein
RA 1,962,923 C→A 8.0% M233I (ATG→ATT cheR ← chemotaxis regulator, protein‑glutamate methyltransferase
RA 1,969,291 G→T 100% I97I (ATC→ATA cheA ← fused chemotactic sensory histidine kinase in two‑component regulatory system with CheB and CheY: sensory histidine kinase/signal sensing protein
RA 1,975,265 C→A 17.0% D202Y (GAT→TAT)  otsB ← trehalose‑6‑phosphate phosphatase, biosynthetic
RA 1,980,472 C→A 46.2% L23I (CTC→ATC)  ftnB → ferritin B, putative ferrous iron reservoir
RA 1,984,478 G→T 44.9% P208Q (CCG→CAG)  yecA ← UPF0149 family protein
RA 1,984,987 C→A 91.2% T38T (ACG→ACT yecA ← UPF0149 family protein
RA 1,985,366 G→T 16.1% noncoding (17/87 nt) leuZ ← tRNA‑Leu
RA 1,986,289 T→A 100% N4Y (AAT→TAT)  pgsA ← phosphatidylglycerophosphate synthetase
RA 1,991,843 G→A 15.4% L40F (CTC→TTC)  yecS ← ABC family putative inner membrane permease
RA 1,993,543 G→T 5.4% V108V (GTC→GTA fliY ← cystine transporter subunit
RA 1,996,506 G→T 8.8% T194T (ACC→ACA fliC ← flagellar filament structural protein (flagellin)
RA 1,997,314 G→T 100% intergenic (‑227/‑39) fliC ← / → fliD flagellar filament structural protein (flagellin)/flagellar filament capping protein
RA 1,999,632 G→T 93.4% intergenic (+73/‑5) fliT → / → amyA putative flagellar synthesis and assembly chaperone/cytoplasmic alpha‑amylase
RA 2,000,765 G→T 7.7% D377Y (GAT→TAT)  amyA → cytoplasmic alpha‑amylase
RA 2,004,533 G→T 5.8% T151T (ACG→ACT yedL → putative acyl transferase
RA 2,005,913 T→A 44.4% intergenic (‑81/‑70) yedN ← / → intG pseudogene, IpaH/YopM family/pseudogene, phage integrase family
RA 2,015,451 T→A 50.7% G34G (GGT→GGA fliP → flagellar biosynthesis protein
RA 2,018,422 T→A 44.6% intergenic (‑118/‑45) dsrB ← / → yodD uncharacterized protein/uncharacterized protein
RA 2,020,166 C→A 100% D445Y (GAC→TAC)  yedQ ← putative membrane‑anchored diguanylate cyclase
RA 2,021,794 C→A 7.1% V20F (GTC→TTC)  yodC ← uncharacterized protein
RA 2,023,279 C→A 40.5% T87K (ACG→AAG)  yedA → amino acid exporter for phenylalanine, threonine
RA 2,029,767 T→A 11.5% V151D (GTT→GAT)  hchA → glyoxalase III and Hsp31 molecular chaperone
RA 2,034,861 G→T 13.3% A2A (GCG→GCT zinT → zinc and cadmium binding protein, periplasmic
RA 2,035,090 C→A 91.2% Q79K (CAG→AAG)  zinT → zinc and cadmium binding protein, periplasmic
RA 2,039,694 C→T 14.1% R426C (CGC→TGC)  yeeJ → putative adhesin
RA 2,046,600 G→T 5.7% pseudogene (210/1053 nt) yeeL ← pseudogene, glycosyltransferase homology
RA 2,060,661 T→A 33.4% N48Y (AAC→TAC)  insH1 ← IS5 transposase and trans‑activator
RA 2,074,680 A→T 100% W22R (TGG→AGG)  sbmC ← DNA gyrase inhibitor
RA 2,075,255 T→A 17.3% V258V (GTA→GTT dacD ← D‑alanyl‑D‑alanine carboxypeptidase (penicillin‑binding protein 6b)
RA 2,077,212 A→T 91.4% N326Y (AAT→TAT)  sbcB → exodeoxyribonuclease I; exonuclease I
RA 2,082,619 C→T 48.7% intergenic (‑10/+73) yeeZ ← / ← yoeB putative epimerase/toxin of the YoeB‑YefM toxin‑antitoxin system
RA 2,086,004 C→A 5.1% A42A (GCC→GCA hisC → histidinol‑phosphate aminotransferase
RA 2,098,995 C→A 100% G182* (GGA→TGA)  wbbI ← d‑Galf:alpha‑d‑Glc beta‑1,6‑galactofuranosyltransferase
RA 2,101,912 T→G 8.7% E385A (GAG→GCG)  wzxB ← putative polisoprenol‑linked O‑antigen transporter
RA 2,102,786 C→T 35.9% V94I (GTT→ATT)  wzxB ← putative polisoprenol‑linked O‑antigen transporter
RA 2,108,199 C→T 14.5% M393I (ATG→ATA wcaM ← colanic acid biosynthesis protein
RA 2,108,219:1 +A 100% coding (1159/1395 nt) wcaM ← colanic acid biosynthesis protein
RA 2,110,346 G→A 93.1% T88I (ACC→ATC)  wcaL ← putative glycosyl transferase
RA 2,114,414 C→A 13.5% V208F (GTC→TTC)  wcaJ ← colanic biosynthesis UDP‑glucose lipid carrier transferase
RA 2,114,911 A→T 100% L42Q (CTG→CAG)  wcaJ ← colanic biosynthesis UDP‑glucose lipid carrier transferase
RA 2,122,266 G→T 5.1% S35* (TCG→TAG)  wcaF ← putative acyl transferase
RA 2,124,797 C→A 17.5% R252L (CGT→CTT)  wcaC ← putative glycosyl transferase
RA 2,130,684 G→T 45.8% S14* (TCA→TAA)  wza ← colanic acid export protein; outer membrane auxillary lipoprotein
RA 2,130,777 T→A 8.2% intergenic (‑53/‑606) wza ← / → yegH colanic acid export protein; outer membrane auxillary lipoprotein/inner membrane protein
RA 2,135,016 C→A 12.5% V26V (GTG→GTT asmA ← suppressor of OmpF assembly mutants; putative outer membrane protein assembly factor; inner membrane‑anchored periplasmic protein
RA 2,137,659 C→A 38.2% R305R (CGG→AGG)  yegE → putative diguanylate cyclase
RA 2,137,749 C→A 11.2% L335I (CTC→ATC)  yegE → putative diguanylate cyclase
RA 2,139,450 G→T 38.3% E902* (GAG→TAG)  yegE → putative diguanylate cyclase
RA 2,139,910 G→T 100% R1055L (CGA→CTA)  yegE → putative diguanylate cyclase
RA 2,144,474 C→A 100% intergenic (‑8/‑192) yegI ← / → yegJ protein kinase‑related putative non‑specific DNA‑binding protein/uncharacterized protein
RA 2,145,887 G→T 13.3% Q23K (CAG→AAG)  yegK ← ser/thr phosphatase‑related protein
RA 2,146,030 T→A 16.9% S194C (AGT→TGT)  yegL ← VMA domain protein
RA 2,149,603 A→T 100% E287V (GAA→GTA)  mdtB → multidrug efflux system, subunit B
RA 2,152,444 C→A 7.8% A193E (GCG→GAG)  mdtC → multidrug efflux system, subunit C
RA 2,155,768 T→C 47.5% I275T (ATT→ACT)  mdtD → putative arabinose efflux transporter
RA 2,162,105 T→A 19.0% intergenic (‑318/‑88) yegR ← / → yegS uncharacterized protein/phosphatidylglycerol kinase, metal‑dependent
RA 2,163,087 C→A 5.8% R299S (CGT→AGT)  yegS → phosphatidylglycerol kinase, metal‑dependent
RA 2,168,795 C→A 93.6% D336Y (GAT→TAT)  gatZ ← D‑tagatose 1,6‑bisphosphate aldolase 2, subunit
RA 2,170,713 C→A 8.1% intergenic (‑30/+278) gatY ← / ← fbaB D‑tagatose 1,6‑bisphosphate aldolase 2, catalytic subunit/fructose‑bisphosphate aldolase class I
RA 2,172,567 A→T 5.3% T90S (ACT→TCT)  yegT → nucleoside transporter, low affinity
RA 2,176,158 C→T 9.2% A35T (GCC→ACC)  yegW ← putative DNA‑binding transcriptional regulator
RA 2,177,743 C→A 35.9% D85Y (GAT→TAT)  thiD ← bifunctional hydroxy‑methylpyrimidine kinase/ hydroxy‑phosphomethylpyrimidine kinase
RA 2,178,987 C→A 14.1% intergenic (‑207/+16) thiM ← / ← rcnR hydoxyethylthiazole kinase/transcriptional repressor of rcnA
RA 2,179,205 G→T 100% A24E (GCG→GAG)  rcnR ← transcriptional repressor of rcnA
RA 2,181,645 A→G 100% N83N (AAT→AAC yehA ← putative fimbrial‑like adhesin protein
RA 2,191,496 C→A 5.7% pseudogene (1544/2847 nt) yehH → DUF4132 family pseudogene; defective yehI paralog; molybdate metabolism regulator, first fragment; molybdate metabolism regulator, second fragment 2; yehI' molR mutations have phenotypes and the N‑terminal molR fragment of yehI' may be expressed and may have retained or evolved MolR function
RA 2,192,748 T→A 19.9% pseudogene (2796/2847 nt) yehH → DUF4132 family pseudogene; defective yehI paralog; molybdate metabolism regulator, first fragment; molybdate metabolism regulator, second fragment 2; yehI' molR mutations have phenotypes and the N‑terminal molR fragment of yehI' may be expressed and may have retained or evolved MolR function
RA 2,194,695 T→A 100% L313Q (CTA→CAA)  yehI → DUF4132 domain‑containing protein
RA 2,195,449 A→T 100% E564D (GAA→GAT yehI → DUF4132 domain‑containing protein
RA 2,197,430 G→T 7.2% intergenic (+40/‑21) yehI → / → yehK DUF4132 domain‑containing protein/uncharacterized protein
RA 2,204,432 G→T 17.5% pseudogene (1854/2001 nt) yehQ → pseudogene
RA 2,209,162 C→A 94.3% I9I (ATC→ATA yohO → putative membrane protein
RA 2,216,296 C→A 100% I211I (ATC→ATA dld → D‑lactate dehydrogenase, FAD‑binding, NADH independent
RA 2,221,550 G→T 9.3% pseudogene (539/1287 nt) mdtQ ← pseudogene; putative channel/filament proteins
RA 2,223,247 C→T 92.5% W206* (TGG→TGA dusC ← tRNA‑dihydrouridine synthase C
RA 2,225,190 C→T 94.3% G231G (GGC→GGT yohK → LrgB family inner membrane protein
RA 2,225,529 G→T 5.1% S69S (TCG→TCT cdd → cytidine/deoxycytidine deaminase
RA 2,232,373 C→A 8.3% A132A (GCG→GCT mglA ← fused methyl‑galactoside transporter subunits of ABC superfamily: ATP‑binding components
RA 2,233,243 T→G 5.6% K195N (AAA→AAC mglB ← methyl‑galactoside transporter subunit
RA 2,234,532 C→A 7.8% D206Y (GAT→TAT)  galS ← galactose‑ and fucose‑inducible galactose regulon transcriptional isorepressor; mgl operon transcriptional repressor; autorepressor
RA 2,237,098 G→T 100% H12N (CAT→AAT)  folE ← GTP cyclohydrolase I
RA 2,241,222 T→G 5.7% I264L (ATT→CTT)  lysP ← lysine transporter
RA 2,244,455 C→A 15.3% T46K (ACG→AAG)  nfo → endonuclease IV with intrinsic 3'‑5' exonuclease activity
RA 2,246,428 C→A 17.0% T399T (ACG→ACT nupX ← nucleoside permease
RA 2,248,390 G→T 12.9% F92L (TTC→TTA rihB ← ribonucleoside hydrolase 2
RA 2,256,045 A→T 7.0% I310I (ATT→ATA fruB ← fused fructose‑specific PTS enzymes: IIA component/HPr component
RA 2,263,137 C→A 94.3% intergenic (+91/‑321) lpxT → / → mepS lipid A 1‑diphosphate synthase; undecaprenyl pyrophosphate:lipid A 1‑phosphate phosphotransferase/murein DD‑endopeptidase, space‑maker hydrolase, mutational suppressor of prc thermosensitivity, outer membrane lipoprotein
RA 2,264,143 G→A 100% intergenic (+119/‑62) mepS → / → rtn murein DD‑endopeptidase, space‑maker hydrolase, mutational suppressor of prc thermosensitivity, outer membrane lipoprotein/resistance protein for phages lambda and N4, putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 2,281,560 T→A 48.6% pseudogene (834/2525 nt) yejO ← pseudogene, autotransporter outer membrane homology;putative transport; Not classified; putative ATP‑binding component of a transport system
RA 2,287,829 C→A 94.0% S185S (TCG→TCT ccmF ← heme lyase, CcmF subunit
RA 2,289,043 C→A 92.9% W8L (TGG→TTG)  ccmD ← cytochrome c biogenesis protein
RA 2,289,374 C→A 100% V142V (GTG→GTT ccmC ← heme exporter subunit
RA 2,291,194 C→A 40.4% C182F (TGC→TTC)  napC ← quinol dehydrogenase, electron source for NapAB
RA 2,298,128 C→T 8.2% intergenic (+256/+459) eco → / ← mqo ecotin, a serine protease inhibitor/malate dehydrogenase, FAD/NAD(P)‑binding domain
RA 2,303,070 T→G 100% Q272P (CAG→CCG)  ada ← fused DNA‑binding transcriptional dual regulator/O6‑methylguanine‑DNA methyltransferase
RA 2,303,607 A→C 47.7% L93R (CTG→CGG)  ada ← fused DNA‑binding transcriptional dual regulator/O6‑methylguanine‑DNA methyltransferase
RA 2,305,116 C→A 100% intergenic (‑103/+9) apbE ← / ← ompC putative thiamine‑synthetic flavin transferase lipoprotein/outer membrane porin protein C
RA 2,305,135 T→C 100% Y365C (TAC→TGC)  ompC ← outer membrane porin protein C
RA 2,310,213 G→T 47.7% K186N (AAG→AAT rcsB → response regulator in two‑component regulatory system with RcsC and YojN
RA 2,310,604 C→A 14.9% G918C (GGT→TGT)  rcsC ← hybrid sensory kinase in two‑component regulatory system with RcsB and YojN
RA 2,311,008 T→A 16.9% H783L (CAC→CTC)  rcsC ← hybrid sensory kinase in two‑component regulatory system with RcsB and YojN
RA 2,313,511 T→A 43.9% intergenic (‑156/‑11) rcsC ← / → atoS hybrid sensory kinase in two‑component regulatory system with RcsB and YojN/sensory histidine kinase in two‑component regulatory system with AtoC
RA 2,318,825 G→T 5.6% V197V (GTG→GTT atoE → short chain fatty acid transporter
RA 2,321,041 G→T 15.9% F194L (TTC→TTA yfaP ← DUF2135 family protein, putative host defense protein
RA 2,329,729 G→T 18.9% A132E (GCG→GAG)  yfaA ← DUF2138 family protein, putative host defense protein
RA 2,330,502 C→A 92.8% D800Y (GAT→TAT)  gyrA ← DNA gyrase (type II topoisomerase), subunit A
RA 2,342,897 C→A 6.2% D19Y (GAC→TAC)  inaA ← acid‑inducible Kdo/WaaP family putative kinase
RA 2,348,894 T→A 92.3% V384E (GTG→GAG)  glpB → sn‑glycerol‑3‑phosphate dehydrogenase (anaerobic), membrane anchor subunit
RA 2,352,573 C→A 100% P353P (CCG→CCT rhmT ← putative L‑rhamnonate transporter
RA 2,359,673 G→T 100% M89I (ATG→ATT arnB → uridine 5'‑(beta‑1‑threo‑pentapyranosyl‑4‑ulose diphosphate) aminotransferase, PLP‑dependent
RA 2,362,338 T→A 100% L274Q (CTG→CAG)  arnA → fused UDP‑L‑Ara4N formyltransferase/UDP‑GlcA C‑4'‑decarboxylase
RA 2,364,394 C→A 46.8% S3* (TCG→TAG)  arnT → 4‑amino‑4‑deoxy‑L‑arabinose transferase
RA 2,366,555 T→G 17.8% F62C (TTT→TGT)  arnF → undecaprenyl phosphate‑alpha‑L‑ara4N exporter; flippase ArnEF subunit
RA 2,370,361:1 +G 100% coding (711/759 nt) menH ← 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase
RA 2,370,987 C→A 100% E29* (GAA→TAA)  menH ← 2‑succinyl‑6‑hydroxy‑2, 4‑cyclohexadiene‑1‑carboxylate synthase
RA 2,372,282 C→A 10.1% D153Y (GAC→TAC)  menD ← 2‑succinyl‑5‑enolpyruvyl‑6‑hydroxy‑3‑ cyclohexene‑1‑carboxylate synthase; SEPHCHC synthase
RA 2,373,129 C→A 18.8% D332Y (GAT→TAT)  menF ← isochorismate synthase 2
RA 2,376,959 C→T 8.5% N256N (AAC→AAT elaD → protease, capable of cleaving an AMC‑ubiquitin model substrate
RA 2,378,963 A→T 14.2% L80* (TTG→TAG)  yfbK ← Von Willebrand factor domain putative lipoprotein
RA 2,380,078 C→T 92.2% S247F (TCT→TTT)  yfbL → putative peptidase
RA 2,380,320 C→A 7.7% intergenic (+10/‑93) yfbL → / → yfbM putative peptidase/DUF1877 family protein
RA 2,383,897 C→A 100% R363L (CGC→CTC)  nuoN ← NADH:ubiquinone oxidoreductase, membrane subunit N
RA 2,392,190 G→T 43.2% V485V (GTC→GTA nuoG ← NADH:ubiquinone oxidoreductase, chain G
RA 2,395,151 C→A 15.0% T127T (ACG→ACT nuoE ← NADH:ubiquinone oxidoreductase, chain E
RA 2,399,210 G→T 100% S304* (TCA→TAA)  lrhA ← transcriptional repressor of flagellar, motility and chemotaxis genes
RA 2,400,858 C→A 7.0% intergenic (‑738/‑182) lrhA ← / → alaA transcriptional repressor of flagellar, motility and chemotaxis genes/valine‑pyruvate aminotransferase 2
RA 2,405,946 T→G 100% Q43P (CAG→CCG)  yfbU ← UPF0304 family protein
RA 2,412,205 C→A 92.8% D151Y (GAT→TAT)  yfcD ← putative NUDIX hydrolase
RA 2,416,101 C→A 100% intergenic (+21/+27) yfcH → / ← yfcI putative NAD‑dependent nucleotide‑sugar epimerase/transposase_31 family protein
RA 2,417,358 C→A 17.1% E211* (GAA→TAA)  hisP ← histidine/lysine/arginine/ornithine transporter subunit
RA 2,422,841 C→A 100% D293Y (GAT→TAT)  purF ← amidophosphoribosyltransferase
RA 2,423,034 G→T 45.7% G228G (GGC→GGA purF ← amidophosphoribosyltransferase
RA 2,424,074 C→T 100% D57N (GAC→AAC)  cvpA ← colicin V production membrane protein
RA 2,424,254 G→T 10.4% intergenic (‑12/+247) cvpA ← / ← dedD colicin V production membrane protein/membrane‑anchored periplasmic protein involved in septation
RA 2,425,587 C→A 41.0% D279Y (GAC→TAC)  folC ← bifunctional folylpolyglutamate synthase/ dihydrofolate synthase
RA 2,437,156 G→T 8.2% P638P (CCG→CCT mnmC → fused 5‑methylaminomethyl‑2‑thiouridine‑forming enzyme methyltransferase and FAD‑dependent demodification enzyme
RA 2,438,410 C→A 42.3% A210A (GCG→GCT yfcA ← UPF0721 family inner membrane protein
RA 2,442,971 C→A 16.5% E186D (GAG→GAT yfcO ← DUF2544 family putative outer membrane protein
RA 2,443,918 T→G 12.1% Y51S (TAT→TCT)  yfcP ← putative fimbrial‑like adhesin protein
RA 2,444,107 T→G 44.6% N150H (AAT→CAT)  yfcQ ← putative fimbrial‑like adhesin protein
RA 2,450,335 C→T 100% intergenic (‑44/+159) sixA ← / ← fadJ phosphohistidine phosphatase/fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase
RA 2,450,346 G→T 100% intergenic (‑55/+148) sixA ← / ← fadJ phosphohistidine phosphatase/fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase
RA 2,452,454 G→T 100% P62Q (CCG→CAG)  fadJ ← fused enoyl‑CoA hydratase and epimerase and isomerase/3‑hydroxyacyl‑CoA dehydrogenase
RA 2,453,358 G→T 17.7% I197I (ATC→ATA fadI ← beta‑ketoacyl‑CoA thiolase, anaerobic, subunit
RA 2,454,297 T→G 100% E39D (GAA→GAC yfcZ ← UPF0381 family protein
RA 2,456,508 A→T 36.0% S6S (TCA→TCT yfdF → uncharacterized protein
RA 2,456,705 C→A 6.0% S72Y (TCC→TAC)  yfdF → uncharacterized protein
RA 2,457,130 C→A 7.8% R214S (CGT→AGT)  yfdF → uncharacterized protein
RA 2,459,304 C→A 7.9% I175I (ATC→ATA yfdC → putative inner membrane protein
RA 2,459,976 G→T 5.6% intergenic (+114/‑48) argW → / → intS tRNA‑Arg/CPS‑53 (KpLE1) prophage; putative prophage CPS‑53 integrase
RA 2,463,760 T→A 36.8% V384E (GTA→GAA)  gtrS → serotype‑specific glucosyl transferase, CPS‑53 (KpLE1) prophage
RA 2,472,897 A→T 41.9% T73S (ACT→TCT)  dsdA → D‑serine dehydratase
RA 2,474,353 G→T 6.6% Q435K (CAG→AAG)  emrY ← putative multidrug efflux system
RA 2,474,418 G→T 100% S413* (TCA→TAA)  emrY ← putative multidrug efflux system
RA 2,481,974 G→T 5.1% S225* (TCA→TAA)  yfdE ← acetyl‑CoA:oxalate CoA‑transferase
RA 2,487,835 G→T 11.2% S16Y (TCT→TAT)  yfdX ← uncharacterized protein
RA 2,491,279 G→T 16.4% R166S (CGT→AGT)  alaC ← valine‑pyruvate aminotransferase 3
RA 2,494,310 C→A 11.5% T150K (ACG→AAG)  ypdB → response regulator activating yhjX; pyruvate‑responsive YpdAB two‑component system
RA 2,495,918 C→A 5.9% V683F (GTT→TTT)  fryA ← putative PTS enzyme, Hpr component/enzyme I component/enzyme IIA component
RA 2,497,946 G→T 7.3% L7I (CTC→ATC)  fryA ← putative PTS enzyme, Hpr component/enzyme I component/enzyme IIA component
RA 2,501,358 G→T 15.4% R6S (CGC→AGC)  fryC ← putative enzyme IIC component of PTS
RA 2,511,317 C→A 15.8% intergenic (‑6/+203) yfeA ← / ← alaX putative diguanylate cyclase/tRNA‑Ala
RA 2,516,301 G→T 44.7% L348L (CTC→CTA xapB ← xanthosine transporter
RA 2,519,697 G→T 5.0% R173R (CGC→CGA yfeR ← transcriptional regulator of yefH
RA 2,520,652 C→A 100% I116I (ATC→ATA yfeH → putative inorganic ion transporter
RA 2,522,624 C→A 48.0% A304A (GCG→GCT ligA ← DNA ligase, NAD(+)‑dependent
RA 2,526,851 A→T 17.9% intergenic (+112/‑272) cysK → / → ptsH cysteine synthase A, O‑acetylserine sulfhydrolase A subunit/phosphohistidinoprotein‑hexose phosphotransferase component of PTS system (Hpr)
RA 2,536,466 A→T 5.5% V141E (GTG→GAG)  cysP ← thiosulfate‑binding protein
RA 2,542,627 T→G 91.3% I389M (ATT→ATG yfeW → penicillin binding protein PBP4B; weak DD‑carboxypeptidase activity
RA 2,545,086 C→A 46.5% D138Y (GAT→TAT)  ypeA ← putative acyl‑CoA transferase
RA 2,549,676 C→A 100% L28L (CTG→CTT eutL ← putative ethanol utilization carboxysome structural protein
RA 2,549,778 C→A 46.1% M293I (ATG→ATT eutC ← ethanolamine ammonia‑lyase, small subunit (light chain)
RA 2,552,999 A→T 10.1% A261A (GCA→GCT intZ → CPZ‑55 prophage; putative phage integrase
RA 2,555,542 C→A 15.6% R25R (CGG→AGG)  yffO → CPZ‑55 prophage; uncharacterized protein
RA 2,556,759 G→A 11.7% intergenic (+283/‑192) yffP → / → yffQ CPZ‑55 prophage; uncharacterized protein/CPZ‑55 prophage; uncharacterized protein
RA 2,556,786 G→T 7.9% intergenic (+310/‑165) yffP → / → yffQ CPZ‑55 prophage; uncharacterized protein/CPZ‑55 prophage; uncharacterized protein
RA 2,561,221 C→A 47.8% P82P (CCG→CCT eutH ← ethanolamine transporter
RA 2,562,068 G→T 5.3% A268E (GCG→GAG)  eutG ← ethanol dehydrogenase involved in ethanolamine utilization; aldehyde reductase, converts acetaldehyde to ethanol
RA 2,567,211 C→A 8.3% D152Y (GAT→TAT)  eutT ← cobalamin adenosyltransferase involved in ethanolamine utilization
RA 2,568,720 C→T 100% A33T (GCC→ACC)  eutP ← putative P‑loop NTPase ethanolamine utilization protein
RA 2,569,792 G→T 14.5% R649S (CGT→AGT)  maeB ← malic enzyme: putative oxidoreductase/putative phosphotransacetylase
RA 2,574,820 C→A 8.5% A609E (GCG→GAG)  tktB → transketolase 2, thiamine triphosphate‑binding
RA 2,576,325 C→A 100% E171D (GAG→GAT nudK ← GDP‑mannose pyrophosphatase
RA 2,587,029:1 +G 100% coding (101/699 nt) ypfH ← palmitoyl‑CoA esterase activity, uncertain physiological substrate
RA 2,589,808 G→T 12.8% Q97K (CAG→AAG)  ypfJ ← putative neutral zinc metallopeptidase
RA 2,589,933 G→A 100% T55I (ACC→ATC)  ypfJ ← putative neutral zinc metallopeptidase
RA 2,597,173 T→G 88.7% L666R (CTG→CGG)  hyfB → hydrogenase 4, membrane subunit
RA 2,601,404 C→T 21.8% L377F (CTC→TTC)  hyfF → hydrogenase 4, membrane subunit
RA 2,603,728 A→C 45.1% Q69P (CAG→CCG)  hyfH → hydrogenase 4, Fe‑S subunit
RA 2,606,516 G→T 100% D420Y (GAC→TAC)  hyfR → hydrogenase‑4 transcriptional activator
RA 2,610,919 C→A 100% intergenic (+3/‑18) bepA → / → yfgD periplasmic metalloprotease and chaperone for OM protein maintenance and assembly/putative oxidoreductase
RA 2,614,168 C→A 100% D22Y (GAT→TAT)  upp ← uracil phosphoribosyltransferase
RA 2,615,370 C→A 53.0% S272Y (TCT→TAT)  purM → phosphoribosylaminoimidazole synthetase
RA 2,618,693 G→T 89.3% E74* (GAA→TAA)  ppx → exopolyphosphatase
RA 2,628,587 C→A 7.2% Q333K (CAA→AAA)  xseA → exonuclease VII, large subunit
RA 2,632,012 C→A 100% intergenic (‑1/+10) bamB ← / ← yfgM BamABCDE complex OM biogenesis lipoprotein/putative anti‑RcsB factor
RA 2,633,402 C→A 5.3% R178L (CGC→CTC)  hisS ← histidyl tRNA synthetase
RA 2,643,336 C→A 7.0% D771Y (GAC→TAC)  yfhM ← bacterial alpha2‑macroglobulin colonization factor ECAM; anti‑host protease defense factor; periplasmic inner membrane‑anchored lipoprotein
RA 2,645,592 C→A 5.6% D19Y (GAC→TAC)  yfhM ← bacterial alpha2‑macroglobulin colonization factor ECAM; anti‑host protease defense factor; periplasmic inner membrane‑anchored lipoprotein
RA 2,651,665 G→T 100% G210G (GGC→GGA hscA ← DnaK‑like molecular chaperone specific for IscU
RA 2,658,679 G→T 45.0% intergenic (+76/‑115) yfhR → / → csiE putative S9 family prolyl oligopeptidase/stationary phase inducible protein
RA 2,659,594 C→A 7.1% L267L (CTC→CTA csiE → stationary phase inducible protein
RA 2,664,675 C→A 5.2% A31E (GCG→GAG)  hcaB → 2,3‑dihydroxy‑2,3‑dihydrophenylpropionate dehydrogenase
RA 2,665,772 G→T 5.2% E123* (GAA→TAA)  hcaD → phenylpropionate dioxygenase, ferredoxin reductase subunit
RA 2,669,978 C→A 91.6% A69A (GCG→GCT yphD ← inner membrane putative ABC superfamily sugar transporter permease
RA 2,670,769 C→A 5.9% E318* (GAA→TAA)  yphE ← putative sugar transporter subunit of ABC superfamily, ATP‑binding component
RA 2,671,274 C→A 100% T149T (ACG→ACT yphE ← putative sugar transporter subunit of ABC superfamily, ATP‑binding component
RA 2,681,873 T→A 100% Q97L (CAG→CTG)  glrR ← response regulator regulating glmY sRNA in two‑component system with sensor protein GlrK
RA 2,683,829 C→A 94.5% R210L (CGT→CTT)  glrK ← sensor protein kinase regulating glmY sRNA in two‑component system with response regulator GlrR
RA 2,689,267 C→A 8.0% I36I (ATC→ATA mltF → membrane‑bound lytic transglycosylase F, murein hydrolase
RA 2,692,793 C→A 91.3% H226N (CAT→AAT)  yfhH → putative DNA‑binding transcriptional regulator
RA 2,694,843 G→T 94.1% I82I (ATC→ATA pdxJ ← pyridoxine 5'‑phosphate synthase
RA 2,699,380 C→A 90.4% P368P (CCG→CCT lepA ← back‑translocating elongation factor EF4, GTPase
RA 2,709,841 T→A 31.2% intergenic (‑33/‑272) grcA ← / → ung autonomous glycyl radical cofactor/uracil‑DNA‑glycosylase
RA 2,711,755 C→A 6.0% D45Y (GAC→TAC)  yfiF ← putative methyltransferase
RA 2,715,643 G→T 100% E778* (GAA→TAA)  pka → protein lysine acetyltransferase
RA 2,719,426 T→C 100% intergenic (‑321/+2) kgtP ← / ← rrfG alpha‑ketoglutarate transporter/5S ribosomal RNA of rrnG operon
RA 2,725,657 C→A 12.5% D626Y (GAC→TAC)  clpB ← protein disaggregation chaperone
RA 2,725,747 G→T 8.5% R596S (CGC→AGC)  clpB ← protein disaggregation chaperone
RA 2,726,786 C→A 100% A249A (GCG→GCT clpB ← protein disaggregation chaperone
RA 2,733,753 C→T 100% E253K (GAG→AAG)  aroF ← 3‑deoxy‑D‑arabino‑heptulosonate‑7‑phosphate synthase, tyrosine‑repressible
RA 2,735,293 A→T 5.3% I20I (ATA→ATT yfiR → putative periplasmic inhibitor of YfiN activity
RA 2,738,750 T→G 5.5% V176V (GTA→GTC rimM ← 16S rRNA processing protein
RA 2,740,948 C→A 51.0% T69T (ACG→ACT ffh ← Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)
RA 2,741,288 C→A 38.6% intergenic (‑134/‑33) ffh ← / → ypjD Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)/cytochrome c assembly protein family inner membrane protein
RA 2,748,332 C→A 10.6% I26I (ATC→ATA smpB → trans‑translation protein
RA 2,750,424 G→T 48.1% E303* (GAA→TAA)  intA → CP4‑57 prophage; integrase
RA 2,753,076 G→A 11.3% D245N (GAT→AAT)  yfjI → CP4‑57 prophage; uncharacterized protein
RA 2,753,424 G→T 19.6% G361* (GGA→TGA)  yfjI → CP4‑57 prophage; uncharacterized protein
RA 2,754,840 T→A 10.9% E687V (GAA→GTA)  yfjK ← DEAD/H helicase‑like protein, CP4‑57 putative defective prophage
RA 2,756,683 G→T 37.7% L73I (CTC→ATC)  yfjK ← DEAD/H helicase‑like protein, CP4‑57 putative defective prophage
RA 2,762,153 C→A 40.8% R44S (CGC→AGC)  yfjQ → CP4‑57 prophage; uncharacterized protein
RA 2,763,057 C→A 5.8% intergenic (+212/‑5) yfjQ → / → yfjR CP4‑57 prophage; uncharacterized protein/CP4‑57 prophage; putative DNA‑binding transcriptional regulator
RA 2,767,911 T→A 7.0% V412D (GTC→GAC)  yfjW → CP4‑57 prophage; putative inner membrane protein
RA 2,771,358 G→A 100% intergenic (+217/+147) ypjF → / ← ypjA CP4‑57 prophage; toxin of the YpjF‑YfjZ toxin‑antitoxin system/adhesin‑like autotransporter
RA 2,771,366 G→A 17.3% intergenic (+225/+139) ypjF → / ← ypjA CP4‑57 prophage; toxin of the YpjF‑YfjZ toxin‑antitoxin system/adhesin‑like autotransporter
RA 2,776,219 C→A 15.2% intergenic (‑134/+205) ypjA ← / ← pinH adhesin‑like autotransporter/pseudogene, invertase resolvase family
RA 2,778,281 C→T 19.8% pseudogene (90/1374 nt) ypjC ← pseudogene
RA 2,778,820 G→A 10.2% intergenic (‑450/+301) ypjC ← / ← ileY pseudogene/tRNA‑Ile
RA 2,779,067 C→A 100% intergenic (‑697/+54) ypjC ← / ← ileY pseudogene/tRNA‑Ile
RA 2,779,767 A→T 9.9% pseudogene (12/2253 nt) ygaQ → uncharacterized protein; putative enzyme
RA 2,780,661 C→A 11.3% pseudogene (906/2253 nt) ygaQ → uncharacterized protein; putative enzyme
RA 2,783,587 C→A 41.0% R83S (CGC→AGC)  lhgO → L‑2‑hydroxyglutarate oxidase
RA 2,794,428 G→T 6.0% R35R (CGG→CGT nrdI → NrdEF cluster assembly flavodoxin
RA 2,798,195 A→T 6.0% K8* (AAA→TAA)  proV → glycine betaine transporter subunit
RA 2,799,737 C→A 48.1% V123V (GTC→GTA proW → glycine betaine transporter subunit
RA 2,801,706 C→A 6.9% pseudogene (32/1178 nt) ygaY → pseudogene, major facilitator transporter superfamily;putative transport; Not classified; putative transport protein
RA 2,805,420 C→A 17.1% A212E (GCG→GAG)  emrA → multidrug efflux system
RA 2,808,737 C→A 13.5% M354I (ATG→ATT gshA ← glutamate‑cysteine ligase
RA 2,808,907 C→A 7.5% E298* (GAA→TAA)  gshA ← glutamate‑cysteine ligase
RA 2,808,987 G→T 68.7% S271* (TCG→TAG)  gshA ← glutamate‑cysteine ligase
RA 2,812,678 G→T 6.1% intergenic (‑173/+62) csrA ← / ← alaS pleiotropic regulatory protein for carbon source metabolism/alanyl‑tRNA synthetase
RA 2,819,067 C→A 36.6% intergenic (‑132/‑124) mltB ← / → srlA membrane‑bound lytic murein transglycosylase B/glucitol/sorbitol‑specific enzyme IIC component of PTS
RA 2,819,102 G→T 45.3% intergenic (‑167/‑89) mltB ← / → srlA membrane‑bound lytic murein transglycosylase B/glucitol/sorbitol‑specific enzyme IIC component of PTS
RA 2,823,071 T→A 41.1% L222L (CTT→CTA srlR → sorbitol‑inducible srl operon transcriptional repressor
RA 2,825,783 C→T 100% intergenic (‑135/‑52) norR ← / → norV anaerobic nitric oxide reductase DNA‑binding transcriptional activator/anaerobic nitric oxide reductase flavorubredoxin
RA 2,828,952 C→A 100% T611T (ACG→ACT hypF ← carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases
RA 2,831,086 C→A 89.9% E127* (GAA→TAA)  hydN ← formate dehydrogenase‑H, [4Fe‑4S] ferredoxin subunit
RA 2,835,094 C→A 89.6% P249Q (CCG→CAG)  ascB → cryptic 6‑phospho‑beta‑glucosidase
RA 2,836,192 C→T 9.0% G71S (GGC→AGC)  hycI ← protease involved in processing C‑terminal end of HycE
RA 2,837,721 C→A 8.5% D131Y (GAC→TAC)  hycF ← formate hydrogenlyase complex iron‑sulfur protein
RA 2,840,562 C→A 17.0% V70V (GTG→GTT hycD ← hydrogenase 3, membrane subunit
RA 2,841,044 C→A 100% A519A (GCG→GCT hycC ← hydrogenase 3, membrane subunit
RA 2,846,112 C→A 100% I206I (ATC→ATA hypD → hydrogenase maturation protein
RA 2,846,721 G→T 6.0% D37Y (GAT→TAT)  hypE → carbamoyl dehydratase, hydrogenases 1,2,3 maturation protein
RA 2,848,002 T→A 7.4% C102* (TGT→TGA fhlA → formate hydrogenlyase transcriptional activator
RA 2,850,790 C→A 100% I113I (ATC→ATA mutS → methyl‑directed mismatch repair protein
RA 2,852,854 G→T 7.3% P801P (CCG→CCT mutS → methyl‑directed mismatch repair protein
RA 2,860,460 G→T 10.4% R151S (CGC→AGC)  rpoS ← RNA polymerase, sigma S (sigma 38) factor
RA 2,873,087 G→T 100% V15V (GTC→GTA ygbT ← multifunctional endonuclease Cas1, CRISPR adaptation protein; DNA repair enzyme
RA 2,876,760 C→T 100% G246G (GGG→GGA casA ← CRISP RNA (crRNA) containing Cascade antiviral complex protein
RA 2,878,668 G→T 100% V637V (GTC→GTA ygcB ← R‑loop helicase‑annealase Cas3 needed for Cascade anti‑viral activity
RA 2,879,449 G→T 93.6% S377* (TCA→TAA)  ygcB ← R‑loop helicase‑annealase Cas3 needed for Cascade anti‑viral activity
RA 2,882,865 G→T 13.3% V198V (GTC→GTA cysI ← sulfite reductase, beta subunit, NAD(P)‑binding, heme‑binding
RA 2,884,385 G→T 8.8% V291V (GTC→GTA cysJ ← sulfite reductase, alpha subunit, flavoprotein
RA 2,886,199 C→A 10.9% H62N (CAT→AAT)  ygcN → putative oxidoreductase
RA 2,888,584 G→T 100% I185I (ATC→ATA ygcQ ← putative flavoprotein
RA 2,889,129 C→A 5.6% A4S (GCA→TCA)  ygcQ ← putative flavoprotein
RA 2,893,446 T→A 94.4% K63* (AAA→TAA)  ygcW ← putative dehydrogenase
RA 2,899,073 C→A 5.4% R2S (CGC→AGC)  ygcG → uncharacterized protein
RA 2,902,059 C→T 12.6% V323I (GTC→ATC)  pyrG ← CTP synthetase
RA 2,904,743 C→T 9.2% intergenic (‑45/+33) mazE ← / ← relA antitoxin of the ChpA‑ChpR toxin‑antitoxin system/(p)ppGpp synthetase I/GTP pyrophosphokinase
RA 2,918,415 G→A 7.3% P75P (CCC→CCT syd ← SecY‑interacting protein
RA 2,919,922 G→T 8.5% D86Y (GAT→TAT)  ygdH → UPF0717 family protein
RA 2,920,050 C→A 7.0% I128I (ATC→ATA ygdH → UPF0717 family protein
RA 2,921,101 C→A 6.6% intergenic (+70/‑487) ygdH → / → sdaC UPF0717 family protein/putative serine transporter
RA 2,921,245 G→T 7.5% intergenic (+214/‑343) ygdH → / → sdaC UPF0717 family protein/putative serine transporter
RA 2,927,618 C→A 8.8% Q9K (CAG→AAG)  fucP → L‑fucose transporter
RA 2,931,717 C→A 100% N307K (AAC→AAA fucK → L‑fuculokinase
RA 2,932,832 C→A 7.5% R36S (CGT→AGT)  fucR → l‑fucose operon activator
RA 2,932,835 C→T 87.8% R37C (CGC→TGC)  fucR → l‑fucose operon activator
RA 2,934,843 G→T 100% H50N (CAT→AAT)  ygdD ← UPF0382 family inner membrane protein
RA 2,937,613 G→T 12.2% T306T (ACG→ACT csdA → cysteine sulfinate desulfinase
RA 2,938,035 G→T 17.9% P45P (CCG→CCT csdE → CsdA‑binding activator; Fe‑S protein
RA 2,956,284 C→A 5.1% D78Y (GAT→TAT)  ygdB ← DUF2509 family protein
RA 2,959,004 G→A 100% I131I (ATC→ATT lgt ← phosphatidylglycerol‑prolipoprotein diacylglyceryl transferase
RA 2,961,295 G→T 21.4% R167S (CGC→AGC)  ptsP ← fused PTS enzyme: PEP‑protein phosphotransferase (enzyme I)/GAF domain containing protein
RA 2,962,962 T→A 91.6% intergenic (‑626/‑59) rppH ← / → mutH RNA pyrophosphohydrolase/methyl‑directed mismatch repair protein
RA 2,965,691 C→A 13.3% L246I (CTC→ATC)  tas → putative NADP(H)‑dependent aldo‑keto reductase
RA 2,969,113 A→T 41.4% I87I (ATT→ATA aas ← fused 2‑acylglycerophospho‑ethanolamine acyl transferase/acyl‑acyl carrier protein synthetase
RA 2,970,031 C→A 14.7% S25* (TCA→TAA)  galR → galactose‑inducible d‑galactose regulon transcriptional repressor; autorepressor
RA 2,970,703 C→A 7.8% A249E (GCG→GAG)  galR → galactose‑inducible d‑galactose regulon transcriptional repressor; autorepressor
RA 2,978,097 C→A 12.5% P285P (CCG→CCT yqeF ← short chain acyltransferase
RA 2,978,850 C→A 54.4% V34V (GTG→GTT yqeF ← short chain acyltransferase
RA 2,979,222 C→T 8.9% S6F (TCT→TTT)  yqeG → putative transporter
RA 2,985,256 G→T 12.8% intergenic (+138/‑197) ygeG → / → ygeH SycD‑like chaperone family TPR‑repeat‑containing protein/putative transcriptional regulator
RA 2,985,884 C→T 84.6% I144I (ATC→ATT ygeH → putative transcriptional regulator
RA 2,987,928 C→A 19.3% pseudogene (524/633 nt) ygeK ← pseudogene; putative 2‑component transcriptional regulator
RA 2,988,554 G→A 88.2% intergenic (‑103/+119) ygeK ← / ← ygeN pseudogene; putative 2‑component transcriptional regulator/pseudogene
RA 2,988,641 T→C 20.3% intergenic (‑190/+32) ygeK ← / ← ygeN pseudogene; putative 2‑component transcriptional regulator/pseudogene
RA 2,989,295 C→A 100% pseudogene (85/261 nt) ygeN ← pseudogene
RA 2,993,211 C→A 100% V14L (GTG→TTG)  ygeR ← LysM domain‑containing M23 family putative peptidase; septation lipoprotein
RA 2,993,699 C→A 100% intergenic (‑449/‑5) ygeR ← / → xdhA LysM domain‑containing M23 family putative peptidase; septation lipoprotein/xanthine dehydrogenase, molybdenum binding subunit
RA 2,999,827 C→A 8.7% D69E (GAC→GAA ygeW → putative carbamoyltransferase
RA 3,007,405 A→T 41.1% L65* (TTG→TAG)  yqeB ← XdhC‑CoxI family protein with NAD(P)‑binding Rossman fold
RA 3,009,187 G→T 93.4% intergenic (+90/‑232) mocA → / → ygfK CTP:molybdopterin cytidylyltransferase/putative Fe‑S subunit oxidoreductase subunit
RA 3,017,285 G→T 100% D871Y (GAC→TAC)  xdhD → putative hypoxanthine oxidase, molybdopterin‑binding/Fe‑S binding
RA 3,018,544 G→T 5.4% A279S (GCC→TCC)  xanQ → xanthine permease
RA 3,021,141 T→C 12.2% I221T (ATC→ACC)  ygfQ → putative purine permease
RA 3,024,081 A→C 89.5% V70V (GTT→GTG ygfT ← putative oxidoreductase, Fe‑S subunit/nucleotide‑binding subunit
RA 3,024,983 C→G 94.4% G86G (GGC→GGG uacT → uric acid permease
RA 3,028,224 G→T 15.4% L104I (CTC→ATC)  lysS ← lysine tRNA synthetase, constitutive
RA 3,030,181 G→T 89.5% H429N (CAT→AAT)  recJ ← ssDNA exonuclease, 5' ‑‑> 3'‑specific
RA 3,030,376 C→A 10.3% E364* (GAA→TAA)  recJ ← ssDNA exonuclease, 5' ‑‑> 3'‑specific
RA 3,035,271 G→T 48.3% V200V (GTG→GTT ygfZ → iron‑sulfur cluster repair protein, plumbagin resistance
RA 3,036,052 C→A 47.4% S152S (TCG→TCT yqfA ← hemolysin III family HylIII inner membrane protein
RA 3,039,409 T→G 8.4% intergenic (‑149/+118) ygfF ← / ← gcvP putative NAD(P)‑dependent oxidoreductase with NAD(P)‑binding Rossmann‑fold domain/glycine decarboxylase, PLP‑dependent, subunit (protein P) of glycine cleavage complex
RA 3,039,703 C→A 6.6% A900S (GCG→TCG)  gcvP ← glycine decarboxylase, PLP‑dependent, subunit (protein P) of glycine cleavage complex
RA 3,041,026 C→A 16.7% D459Y (GAC→TAC)  gcvP ← glycine decarboxylase, PLP‑dependent, subunit (protein P) of glycine cleavage complex
RA 3,041,321 G→T 5.2% I360I (ATC→ATA gcvP ← glycine decarboxylase, PLP‑dependent, subunit (protein P) of glycine cleavage complex
RA 3,044,437 T→A 49.9% intergenic (‑411/+37) gcvT ← / ← ubiI aminomethyltransferase, tetrahydrofolate‑dependent, subunit (T protein) of glycine cleavage complex/2‑octaprenylphenol hydroxylase, FAD‑dependent
RA 3,044,464 G→A 100% intergenic (‑438/+10) gcvT ← / ← ubiI aminomethyltransferase, tetrahydrofolate‑dependent, subunit (T protein) of glycine cleavage complex/2‑octaprenylphenol hydroxylase, FAD‑dependent
RA 3,046,473 G→T 46.2% N135K (AAC→AAA ubiH ← 2‑octaprenyl‑6‑methoxyphenol hydroxylase, FAD/NAD(P)‑binding
RA 3,048,490 A→T 14.7% L105* (TTG→TAG)  ygfB ← UPF0149 family protein
RA 3,049,220 C→A 8.6% R84R (CGG→AGG)  zapA → FtsZ stabilizer
RA 3,058,769 C→T 93.5% I203I (ATC→ATT scpC → propionyl‑CoA:succinate CoA transferase
RA 3,059,577 G→T 19.4% D473Y (GAT→TAT)  scpC → propionyl‑CoA:succinate CoA transferase
RA 3,062,894 T→A 7.0% V91V (GTA→GTT mscS ← mechanosensitive channel protein, small conductance
RA 3,064,483 C→A 11.9% D41Y (GAC→TAC)  fbaA ← fructose‑bisphosphate aldolase, class II
RA 3,064,914 G→T 100% I356I (ATC→ATA pgk ← phosphoglycerate kinase
RA 3,065,300 C→A 43.4% D228Y (GAT→TAT)  pgk ← phosphoglycerate kinase
RA 3,066,958 G→T 5.7% T31T (ACC→ACA epd ← D‑erythrose 4‑phosphate dehydrogenase
RA 3,068,854 C→A 41.1% E230* (GAG→TAG)  yggF ← fructose 1,6 bisphosphatase isozyme
RA 3,072,841 C→T 6.3% intergenic (‑152/+162) cmtB ← / ← tktA putative mannitol‑specific enzyme IIA component of PTS/transketolase 1, thiamine triphosphate‑binding
RA 3,074,352 C→T 48.8% D215N (GAC→AAC)  tktA ← transketolase 1, thiamine triphosphate‑binding
RA 3,075,114 C→A 100% intergenic (‑120/‑158) tktA ← / → loiP transketolase 1, thiamine triphosphate‑binding/Phe‑Phe periplasmic metalloprotease, OM lipoprotein; low salt‑inducible; heat shock protein that binds Era
RA 3,076,526 C→A 100% D211Y (GAC→TAC)  speB ← agmatinase
RA 3,080,098 T→G 51.8% S12A (TCT→GCT)  metK → S‑adenosylmethionine synthetase
RA 3,080,618 T→A 100% V185E (GTG→GAG)  metK → S‑adenosylmethionine synthetase
RA 3,081,697 T→A 16.2% C19S (TGC→AGC)  galP → D‑galactose transporter
RA 3,084,798 C→A 7.3% L102L (CTC→CTA rsmE → 16S rRNA m(3)U1498 methyltransferase, SAM‑dependent
RA 3,085,649 C→A 7.7% T138K (ACG→AAG)  gshB → glutathione synthetase
RA 3,088,065 C→A 90.6% V125V (GTG→GTT yggR ← putative PilT family AAA+ ATPase
RA 3,089,392 C→A 14.3% L72I (CTC→ATC)  yggT → putative inner membrane protein; compensates for loss in K+ uptake
RA 3,091,476 C→A 6.2% T284K (ACG→AAG)  yggW → HemN family putative oxidoreductase
RA 3,092,182 C→A 15.2% C248F (TGT→TTT)  yggM ← DUF1202 family putative secreted protein
RA 3,096,445 A→T 13.9% Q25L (CAA→CTA)  mutY → adenine DNA glycosylase
RA 3,097,262 C→T 88.3% F297F (TTC→TTT mutY → adenine DNA glycosylase
RA 3,099,851 C→A 12.1% S260* (TCG→TAG)  nupG → nucleoside transporter
RA 3,100,053 C→T 45.1% I327I (ATC→ATT nupG → nucleoside transporter
RA 3,104,247 C→A 15.3% R80L (CGA→CTA)  yghD ← putative membrane‑anchored secretion pathway M‑type protein
RA 3,110,213 T→A 7.9% A753A (GCA→GCT yghJ ← DUF4092 family putative lipoprotein peptidase
RA 3,110,751 C→A 100% R574L (CGT→CTT)  yghJ ← DUF4092 family putative lipoprotein peptidase
RA 3,111,434 C→A 100% A346A (GCG→GCT yghJ ← DUF4092 family putative lipoprotein peptidase
RA 3,118,925 C→A 17.8% P319P (CCG→CCT glcE ← glycolate oxidase FAD binding subunit
RA 3,120,216 C→A 93.8% D389Y (GAT→TAT)  glcD ← glycolate oxidase subunit, FAD‑linked
RA 3,121,242 C→A 16.0% D47Y (GAC→TAC)  glcD ← glycolate oxidase subunit, FAD‑linked
RA 3,132,984 G→A 15.5% intergenic (+32/+91) yghU → / ← hybG putative S‑transferase/hydrogenase 2 accessory protein
RA 3,133,918 C→A 14.5% E81* (GAA→TAA)  hybE ← hydrogenase 2‑specific chaperone
RA 3,134,528 C→A 5.6% D40Y (GAT→TAT)  hybD ← maturation protease for hydrogenase 2
RA 3,136,368 G→T 20.9% R386S (CGT→AGT)  hybB ← putative hydrogenase 2 cytochrome b type component
RA 3,142,668 G→T 89.3% L55I (CTC→ATC)  yqhA ← UPF0114 family putative inner membrane protein
RA 3,144,158 C→A 90.8% intergenic (+253/+19) yghA → / ← exbD putative oxidoreductase/membrane spanning protein in TonB‑ExbB‑ExbD complex
RA 3,149,310 C→A 32.7% T199T (ACC→ACA yqhD → aldehyde reductase, NADPH‑dependent
RA 3,164,049 G→T 41.2% M69I (ATG→ATT qseC → quorum sensing sensory histidine kinase in two‑component regulatory system with QseB
RA 3,164,230 C→A 90.0% R130S (CGT→AGT)  qseC → quorum sensing sensory histidine kinase in two‑component regulatory system with QseB
RA 3,173,669 G→T 93.4% A189A (GCG→GCT ygiB → DUF1190 family protein
RA 3,176,051 C→A 11.0% S48* (TCA→TAA)  zupT → zinc transporter
RA 3,176,733 G→T 91.9% intergenic (+51/+439) zupT → / ← ribB zinc transporter/3,4‑dihydroxy‑2‑butanone‑4‑phosphate synthase
RA 3,184,654 A→T 16.8% N222Y (AAT→TAT)  yqiI → fimbrial protein
RA 3,190,426 T→A 5.2% T859S (ACC→TCC)  glnE ← fused deadenylyltransferase/adenylyltransferase for glutamine synthetase
RA 3,203,599 A→T 42.9% W102R (TGG→AGG)  tsaD ← tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; glycation binding protein
RA 3,208,581 C→A 49.4% E84D (GAG→GAT mug ← G/U mismatch‑specific DNA glycosylase; xanthine DNA glycosylase
RA 3,213,497 C→A 13.9% I215I (ATC→ATA patA → putrescine:2‑oxoglutaric acid aminotransferase, PLP‑dependent
RA 3,214,709 C→A 19.2% intergenic (‑103/‑116) ygjH ← / → ebgR putative tRNA binding protein; putative tRNA corner chaperone/transcriptional repressor
RA 3,217,098 C→A 12.1% I369I (ATC→ATA ebgA → evolved beta‑D‑galactosidase, alpha subunit
RA 3,217,289 A→T 89.0% H433L (CAC→CTC)  ebgA → evolved beta‑D‑galactosidase, alpha subunit
RA 3,219,616 A→T 7.6% T8T (ACA→ACT ygjI → putative transporter
RA 3,224,927 C→A 100% intergenic (+329/‑97) ygjK → / → fadH alpha‑glucosidase/2,4‑dienoyl‑CoA reductase, NADH and FMN‑linked
RA 3,225,300 C→A 45.0% Q93K (CAG→AAG)  fadH → 2,4‑dienoyl‑CoA reductase, NADH and FMN‑linked
RA 3,229,926 C→A 49.4% L10I (CTC→ATC)  ygjQ → DUF218 superfamily protein
RA 3,230,857 C→G 91.7% A63G (GCC→GGC)  ygjR → putative NAD(P)‑dependent dehydrogenase
RA 3,231,349 A→C 100% Q227P (CAG→CCG)  ygjR → putative NAD(P)‑dependent dehydrogenase
RA 3,233,218 C→A 15.9% intergenic (+314/‑85) alx → / → sstT putative membrane‑bound redox modulator/sodium:serine/threonine symporter
RA 3,237,654 C→A 14.0% M149I (ATG→ATT uxaC ← uronate isomerase
RA 3,243,768 C→T 6.8% intergenic (+33/‑153) yqjK → / → yqjF uncharacterized protein/putative quinol oxidase subunit
RA 3,245,848 G→T 100% L62L (CTG→CTT yhaH → DUF805 family inner membrane protein
RA 3,251,070 C→A 17.4% P100P (CCG→CCT yhaO ← putative transporter
RA 3,252,258 C→A 100% D251Y (GAT→TAT)  tdcG ← L‑serine dehydratase 3, anaerobic
RA 3,254,793 C→A 38.3% D329Y (GAT→TAT)  tdcE ← pyruvate formate‑lyase 4/2‑ketobutyrate formate‑lyase
RA 3,257,209 C→A 14.0% E390* (GAA→TAA)  tdcC ← L‑threonine/L‑serine transporter
RA 3,258,871 G→T 7.7% L173I (CTC→ATC)  tdcB ← L‑threonine dehydratase, catabolic
RA 3,260,550 C→T 10.1% intergenic (‑126/‑189) tdcA ← / → tdcR tdc operon transcriptional activator/L‑threonine dehydratase operon activator protein
RA 3,262,436 C→T 11.7% S221S (AGC→AGT yhaC → pentapetide repeats‑related protein
RA 3,263,315 T→C 7.8% intergenic (+354/+260) yhaC → / ← rnpB pentapetide repeats‑related protein/RNase P, M1 RNA component
RA 3,263,466 G→T 7.4% intergenic (+505/+109) yhaC → / ← rnpB pentapetide repeats‑related protein/RNase P, M1 RNA component
RA 3,266,646 C→A 100% G91C (GGT→TGT)  garL ← alpha‑dehydro‑beta‑deoxy‑D‑glucarate aldolase
RA 3,267,286 C→A 16.7% P327P (CCG→CCT garP ← putative (D)‑galactarate transporter
RA 3,268,357 C→A 9.2% intergenic (‑91/‑284) garP ← / → garD putative (D)‑galactarate transporter/(D)‑galactarate dehydrogenase
RA 3,271,128 A→C 5.7% T145P (ACC→CCC)  yhaV → toxin of the SohB(PrlF)‑YhaV toxin‑antitoxin system
RA 3,271,233 C→A 17.5% V264V (GTG→GTT agaR ← transcriptional repressor of the aga regulon
RA 3,285,974 C→A 5.2% D241Y (GAC→TAC)  rsmI ← 16S rRNA C1402 2'‑O‑ribose methyltransferase, SAM‑dependent
RA 3,290,970 A→T 6.5% R176R (CGT→CGA yraQ ← putative inner membrane permease
RA 3,292,182 G→T 13.6% G8G (GGC→GGA yraR ← putative nucleoside‑diphosphate‑sugar epimerase
RA 3,292,914 C→A 20.3% D121Y (GAT→TAT)  yhbP ← UPF0306 family protein
RA 3,296,612 G→T 86.5% A255A (GCG→GCT yhbV → U32 peptidase family protein
RA 3,298,059 C→A 17.1% R373L (CGC→CTC)  mtr ← tryptophan transporter of high affinity
RA 3,302,027 G→T 100% S86* (TCG→TAG)  nlpI ← lipoprotein involved in osmotic sensitivity and filamentation
RA 3,311,841 C→A 9.2% intergenic (‑193/‑155) metY ← / → argG tRNA‑Met/argininosuccinate synthetase
RA 3,314,870 C→A 100% A35S (GCG→TCG)  yhbX ← putative EptAB family phosphoethanolamine transferase, inner membrane protein
RA 3,318,271 G→T 40.0% intergenic (‑1/+89) folP ← / ← ftsH 7,8‑dihydropteroate synthase/protease, ATP‑dependent zinc‑metallo
RA 3,324,066 C→A 45.7% E350* (GAA→TAA)  obgE ← GTPase involved in cell partioning and DNA repair
RA 3,329,704 G→T 15.8% V50V (GTC→GTA murA ← UDP‑N‑acetylglucosamine 1‑carboxyvinyltransferase
RA 3,332,632 G→T 19.7% L265I (CTT→ATT)  mlaF ← ABC transporter maintaining OM lipid asymmetry, ATP‑binding protein
RA 3,334,464 C→A 11.2% S277R (AGC→AGA yrbG → putative calcium/sodium:proton antiporter
RA 3,334,892 G→T 41.7% D90Y (GAT→TAT)  kdsD → D‑arabinose 5‑phosphate isomerase
RA 3,335,651 C→A 18.0% S7* (TCG→TAG)  kdsC → 3‑deoxy‑D‑manno‑octulosonate 8‑phosphate phosphatase
RA 3,345,640 A→T 5.9% Y249N (TAC→AAC)  arcB ← aerobic respiration control sensor histidine protein kinase, cognate to two‑component response regulators ArcA and RssB
RA 3,345,737 A→C 9.4% D216E (GAT→GAG arcB ← aerobic respiration control sensor histidine protein kinase, cognate to two‑component response regulators ArcA and RssB
RA 3,347,778 G→A 94.4% intergenic (‑369/‑306) yhcC ← / → gltB putative Fe‑S oxidoreductase, Radical SAM superfamily protein/glutamate synthase, large subunit
RA 3,351,650 G→T 92.2% E1189D (GAG→GAT gltB → glutamate synthase, large subunit
RA 3,354,405 C→T 100% intergenic (+430/‑130) gltD → / → gltF glutamate synthase, 4Fe‑4S protein, small subunit/periplasmic protein
RA 3,360,045 G→T 33.1% F11L (TTC→TTA insH1 ← IS5 transposase and trans‑activator
RA 3,365,253 G→T 5.4% I227I (ATC→ATA nanT ← sialic acid transporter
RA 3,365,607 G→T 100% I109I (ATC→ATA nanT ← sialic acid transporter
RA 3,368,168 C→T 19.3% intergenic (‑320/‑60) nanR ← / → dcuD transcriptional repressor of the nan operon, induced by sialic acid/putative transporter
RA 3,369,534 C→A 5.1% A436E (GCG→GAG)  dcuD → putative transporter
RA 3,371,948 G→A 9.2% T21T (ACC→ACT rplM ← 50S ribosomal subunit protein L13
RA 3,372,318 G→T 41.3% R347R (CGG→AGG)  yhcM ← putative AFG1‑like family P‑loop ATPase
RA 3,373,985 C→A 100% intergenic (+37/‑117) yhcB → / → degQ DUF1043 family inner membrane‑anchored protein/serine endoprotease, periplasmic
RA 3,375,260 G→T 100% D387Y (GAT→TAT)  degQ → serine endoprotease, periplasmic
RA 3,377,958 G→T 10.0% intergenic (‑331/‑104) mdh ← / → argR malate dehydrogenase, NAD(P)‑binding/l‑arginine‑responsive arginine metabolism regulon transcriptional regulator
RA 3,381,195 G→T 12.7% S118* (TCG→TAG)  aaeB ← p‑hydroxybenzoic acid efflux system component
RA 3,385,516 A→T 5.5% intergenic (‑129/+301) tldD ← / ← yhdP putative peptidase/DUF3971‑AsmA2 domains protein
RA 3,385,571 C→G 6.1% intergenic (‑184/+246) tldD ← / ← yhdP putative peptidase/DUF3971‑AsmA2 domains protein
RA 3,392,935 C→T 11.7% V135I (GTT→ATT)  mreC ← cell wall structural complex MreBCD transmembrane component MreC
RA 3,395,059 C→A 42.7% V545F (GTC→TTC)  csrD ← targeting factor for csrBC sRNA degradation
RA 3,396,082 G→T 100% R204S (CGT→AGT)  csrD ← targeting factor for csrBC sRNA degradation
RA 3,397,077 G→T 5.2% A79S (GCC→TCC)  acuI → putative acryloyl‑CoA reductase
RA 3,397,316 C→A 16.5% G158G (GGC→GGA acuI → putative acryloyl‑CoA reductase
RA 3,399,100 C→A 47.9% F102L (TTC→TTA accB → acetyl CoA carboxylase, BCCP subunit
RA 3,404,059 C→A 6.6% R141S (CGC→AGC)  dusB → tRNA‑dihydrouridine synthase B
RA 3,407,007 G→A 91.9% intergenic (‑183/‑216) acrS ← / → acrE acrAB operon transcriptional repressor/cytoplasmic membrane lipoprotein
RA 3,407,969 C→A 8.9% N249K (AAC→AAA acrE → cytoplasmic membrane lipoprotein
RA 3,411,250 G→T 5.9% E953D (GAG→GAT acrF → multidrug efflux system protein
RA 3,412,733 G→T 46.8% pseudogene (268/960 nt) yhdW → pseudogene, amino‑acid transporter homology;putative transport; Not classified; putative periplasmic binding transport protein; periplasmic‑binding component of ABC superfamily
RA 3,415,551 C→A 6.2% P290T (CCT→ACT)  yhdY → putative amino‑acid transporter subunit
RA 3,416,716 G→T 15.7% intergenic (+163/+66) yhdZ → / ← rrfF putative amino‑acid transporter subunit/5S ribosomal RNA of rrnD operon
RA 3,416,890 T→G 7.0% noncoding (12/120 nt) rrfF ← 5S ribosomal RNA of rrnD operon
RA 3,424,363 T→A 5.4% T138S (ACC→TCC)  tsaC ← tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein, threonine‑dependent ADP‑forming ATPase
RA 3,432,676 C→A 9.3% E65* (GAA→TAA)  yhdN ← DUF1992 family protein
RA 3,432,840 C→A 12.8% R10L (CGC→CTC)  yhdN ← DUF1992 family protein
RA 3,433,018 T→G 15.5% E114A (GAG→GCG)  rplQ ← 50S ribosomal subunit protein L17
RA 3,437,638 G→T 15.0% G87G (GGC→GGA rplO ← 50S ribosomal subunit protein L15
RA 3,440,151 G→T 100% I31I (ATC→ATA rpsN ← 30S ribosomal subunit protein S14
RA 3,440,444 G→T 100% S118S (TCC→TCA rplE ← 50S ribosomal subunit protein L5
RA 3,440,832 T→C 100% N99D (AAC→GAC)  rplX ← 50S ribosomal subunit protein L24
RA 3,448,742 C→A 8.2% E6* (GAA→TAA)  gspA ← general secretory pathway component, cryptic
RA 3,451,616 T→G 41.0% V627V (GTT→GTG gspD → general secretory pathway component, cryptic
RA 3,452,566 C→A 44.3% T290K (ACG→AAG)  gspE → general secretory pathway component, cryptic
RA 3,455,789 G→T 5.5% M29I (ATG→ATT gspJ → putative general secretory pathway component, cryptic
RA 3,455,867 C→A 100% I55I (ATC→ATA gspJ → putative general secretory pathway component, cryptic
RA 3,457,607 G→T 17.7% V109V (GTG→GTT gspL → general secretory pathway component, cryptic
RA 3,457,896 C→A 19.3% P206T (CCT→ACT)  gspL → general secretory pathway component, cryptic
RA 3,470,272 C→A 6.6% V169V (GTG→GTT fkpA ← FKBP‑type peptidyl‑prolyl cis‑trans isomerase (rotamase)
RA 3,473,139 G→T 100% I276I (ATC→ATA kefB ← potassium:proton antiporter
RA 3,476,264 C→A 5.9% S539R (AGC→AGA yheS → putative transporter subunit of ABC superfamily: ATP‑binding component
RA 3,479,769 A→T 100% E97D (GAA→GAT crp → cAMP‑activated global transcription factor, mediator of catabolite repression
RA 3,487,320 G→A 15.8% intergenic (+212/‑50) tsgA → / → nirB putative transporter/nitrite reductase, large subunit, NAD(P)H‑binding
RA 3,488,966 G→C 100% A533P (GCC→CCC)  nirB → nitrite reductase, large subunit, NAD(P)H‑binding
RA 3,489,397 C→A 100% F676L (TTC→TTA nirB → nitrite reductase, large subunit, NAD(P)H‑binding
RA 3,495,516 C→A 17.4% S297* (TCG→TAG)  frlB → fructoselysine‑6‑P‑deglycase
RA 3,501,571 C→A 93.4% G127C (GGC→TGC)  php ← phosphotriesterase homology protein
RA 3,504,143 G→T 93.9% R65S (CGT→AGT)  yhfX ← putative pyridoxal 5'‑phosphate binding protein
RA 3,507,749 G→T 100% H224N (CAT→AAT)  rpe ← D‑ribulose‑5‑phosphate 3‑epimerase
RA 3,508,852 G→T 22.8% P141T (CCC→ACC)  dam ← DNA adenine methyltransferase
RA 3,509,102 G→T 5.3% S57R (AGC→AGA dam ← DNA adenine methyltransferase
RA 3,513,424 A→T 93.2% V213V (GTT→GTA hofQ ← DNA catabolic putative fimbrial transporter
RA 3,513,975 C→A 12.4% D30Y (GAC→TAC) 
*135L (TGA→TTA) 
hofQ ←
hofP ←
DNA catabolic putative fimbrial transporter
DNA catabolic protein
RA 3,519,657 G→T 100% intergenic (‑149/‑171) nudE ← / → yrfF adenosine nucleotide hydrolase; substrates include Ap3A, Ap2A, ADP‑ribose, NADH/inner membrane protein
RA 3,521,598 C→A 14.5% Q591K (CAG→AAG)  yrfF → inner membrane protein
RA 3,525,950 C→T 6.6% intergenic (‑152/‑227) yhgE ← / → pck DUF4153 family putative inner membrane protein/phosphoenolpyruvate carboxykinase
RA 3,528,406 G→T 5.3% I274I (ATC→ATA envZ ← sensory histidine kinase in two‑component regulatory system with OmpR
RA 3,535,370 C→A 7.3% S535R (AGC→AGA feoB → fused ferrous iron transporter, protein B: GTP‑binding protein/membrane protein
RA 3,536,360 C→A 11.1% intergenic (+37/‑166) feoC → / → yhgA putative DNA‑binding transcriptional regulator/transposase_31 family protein
RA 3,541,936 G→T 10.2% L498L (CTC→CTA malQ ← 4‑alpha‑glucanotransferase (amylomaltase)
RA 3,543,959 G→T 100% A625E (GCG→GAG)  malP ← maltodextrin phosphorylase
RA 3,544,369 T→A 12.3% E488D (GAA→GAT malP ← maltodextrin phosphorylase
RA 3,544,521 G→T 51.2% H438N (CAC→AAC)  malP ← maltodextrin phosphorylase
RA 3,549,303 G→T 12.1% V302V (GTC→GTA rtcA ← RNA 3'‑terminal phosphate cyclase
RA 3,557,815 T→A 17.7% K709N (AAA→AAT glgP ← glycogen phosphorylase
RA 3,559,991 G→T 15.8% S468* (TCG→TAG)  glgA ← glycogen synthase
RA 3,561,258 C→A 5.7% D46Y (GAT→TAT)  glgA ← glycogen synthase
RA 3,561,574 C→A 100% W372L (TGG→TTG)  glgC ← glucose‑1‑phosphate adenylyltransferase
RA 3,562,409 C→A 14.1% E94* (GAA→TAA)  glgC ← glucose‑1‑phosphate adenylyltransferase
RA 3,563,911 C→A 16.4% E257* (GAA→TAA)  glgX ← glycogen debranching enzyme
RA 3,567,059 C→A 9.2% intergenic (‑197/+76) glgB ← / ← asd 1,4‑alpha‑glucan branching enzyme/aspartate‑semialdehyde dehydrogenase, NAD(P)‑binding
RA 3,568,708 C→A 12.2% S93* (TCA→TAA)  yhgN → UPF0056 family inner membrane protein
RA 3,571,153 C→A 8.5% E312* (GAA→TAA)  gntR ← d‑gluconate inducible gluconate regulon transcriptional repressor
RA 3,571,612 C→T 14.1% A159T (GCC→ACC)  gntR ← d‑gluconate inducible gluconate regulon transcriptional repressor
RA 3,571,618 C→A 52.1% D157Y (GAT→TAT)  gntR ← d‑gluconate inducible gluconate regulon transcriptional repressor
RA 3,571,951 C→A 12.7% E46* (GAA→TAA)  gntR ← d‑gluconate inducible gluconate regulon transcriptional repressor
RA 3,574,500 G→T 12.2% M1M (ATG→ATT) † yhhY → putative acetyltransferase
RA 3,577,507 C→A 51.6% I157I (ATC→ATA insB1 → IS1 transposase B
RA 3,580,302 G→T 8.4% intergenic (‑119/‑1) ggt ← / → yhhA gamma‑glutamyltranspeptidase/DUF2756 family protein
RA 3,584,639 G→T 43.1% I349I (ATC→ATA ugpB ← glycerol‑3‑phosphate transporter subunit
RA 3,590,930 T→A 18.4% intergenic (‑10/‑414) livK ← / → panM leucine transporter subunit/PanD autocleavage accelerator, panothenate synthesis
RA 3,591,211 C→A 7.2% intergenic (‑291/‑133) livK ← / → panM leucine transporter subunit/PanD autocleavage accelerator, panothenate synthesis
RA 3,594,268 C→T 7.7% intergenic (‑125/+120) rpoH ← / ← ftsX RNA polymerase, sigma 32 (sigma H) factor/inner membrane putative ABC superfamily transporter permease
RA 3,598,440 C→A 17.1% N34K (AAC→AAA yhhL → DUF1145 family protein
RA 3,602,056 T→G 5.5% intergenic (+47/+55) zntA → / ← tusA zinc, cobalt and lead efflux system/mnm(5)‑s(2)U34‑tRNA 2‑thiolation sulfurtransferase
RA 3,607,110 C→A 6.0% I28I (ATC→ATA nikA → nickel‑binding, heme‑binding periplasmic protein
RA 3,609,958 C→A 45.0% I139I (ATC→ATA nikC → nickel transporter subunit
RA 3,612,284 G→T 9.0% D113Y (GAT→TAT)  nikR → transcriptional repressor, Ni‑binding
RA 3,612,708 C→A 42.6% L53I (CTC→ATC)  rhsB → Rhs family putative polymorphic toxin, putative neighboring cell growth inhibitor
RA 3,616,947 A→T 11.7% E63D (GAA→GAT yhhH → putative immunity protein for putative polymorphic toxin RhsB
RA 3,622,058 C→A 5.8% D281Y (GAT→TAT)  rbbA ← ribosome‑associated ATPase: ATP‑binding protein/ATP‑binding membrane protein
RA 3,622,863 G→T 37.2% V12V (GTC→GTA rbbA ← ribosome‑associated ATPase: ATP‑binding protein/ATP‑binding membrane protein
RA 3,629,424 T→A 6.4% intergenic (+171/+144) yhiM → / ← yhiN acid resistance protein, inner membrane/putative oxidoreductase
RA 3,629,439 C→A 38.2% intergenic (+186/+129) yhiM → / ← yhiN acid resistance protein, inner membrane/putative oxidoreductase
RA 3,631,760 G→T 7.2% M253I (ATG→ATT pitA → phosphate transporter, low‑affinity; tellurite importer
RA 3,634,084 C→A 6.1% intergenic (+179/‑138) uspA → / → dtpB universal stress global response regulator/dipeptide and tripeptide permease B
RA 3,639,239 G→T 6.6% P165P (CCG→CCT rlmJ → 23S rRNA m(6)A2030 methyltransferase, SAM‑dependent
RA 3,640,170 C→A 14.5% A171E (GCG→GAG)  gor → glutathione oxidoreductase
RA 3,644,531 G→A 5.5% intergenic (+509/‑120) arsC → / → yhiS arsenate reductase/pseudogene
RA 3,646,984 G→T 6.5% pseudogene (394/483 nt) yhiS → pseudogene
RA 3,649,637 G→A 38.3% L6F (CTC→TTC)  hdeB ← acid‑resistance protein
RA 3,649,797 C→A 5.8% E102* (GAA→TAA)  hdeA ← stress response protein acid‑resistance protein
RA 3,652,308 G→T 6.3% intergenic (+55/‑284) gadE → / → mdtE gad regulon transcriptional activator/anaerobic multidrug efflux transporter, ArcA‑regulated
RA 3,652,706 G→T 14.4% V39F (GTC→TTC)  mdtE → anaerobic multidrug efflux transporter, ArcA‑regulated
RA 3,661,610 A→T 7.8% F313L (TTT→TTA yhjA ← putative cytochrome C peroxidase
RA 3,662,660 T→C 100% intergenic (‑112/‑292) yhjA ← / → treF putative cytochrome C peroxidase/cytoplasmic trehalase
RA 3,667,959 C→A 6.2% intergenic (+224/‑187) yhjD → / → yhjE inner membrane putative BrbK family alternate lipid exporter/MFS superfamily sugar transport 1 family protein
RA 3,667,977 C→T 20.8% intergenic (+242/‑169) yhjD → / → yhjE inner membrane putative BrbK family alternate lipid exporter/MFS superfamily sugar transport 1 family protein
RA 3,668,106 G→A 8.8% intergenic (+371/‑40) yhjD → / → yhjE inner membrane putative BrbK family alternate lipid exporter/MFS superfamily sugar transport 1 family protein
RA 3,670,418 C→A 20.0% P431P (CCG→CCT yhjG ← putative inner membrane‑anchored periplasmic AsmA family protein
RA 3,673,169 C→A 36.9% L131I (CTC→ATC)  kdgK → 2‑dehydro‑3‑deoxygluconokinase
RA 3,679,301 T→G 100% Q1078P (CAG→CCG)  bcsC ← cellulose synthase subunit
RA 3,679,324 C→A 94.9% M1070I (ATG→ATT bcsC ← cellulose synthase subunit
RA 3,680,907 C→A 13.1% D543Y (GAC→TAC)  bcsC ← cellulose synthase subunit
RA 3,680,910 G→T 100% H542N (CAT→AAT)  bcsC ← cellulose synthase subunit
RA 3,689,369 C→A 15.3% A59A (GCG→GCT yhjR ← DUF2629 family protein
RA 3,694,707 C→A 21.4% S262* (TCG→TAG)  yhjV → putative transporter
RA 3,698,119 C→A 7.9% M1M (ATG→ATT) † dppC ← dipeptide/heme transporter
RA 3,698,875 G→T 86.9% F92L (TTC→TTA dppB ← dipeptide/heme transporter
RA 3,699,362 C→T 14.3% intergenic (‑212/+96) dppB ← / ← dppA dipeptide/heme transporter/dipeptide transporter
RA 3,701,444 G→A 7.3% intergenic (‑379/+532) dppA ← / ← proK dipeptide transporter/tRNA‑Pro
RA 3,708,413 G→T 13.3% P448T (CCG→ACG)  bisC ← biotin sulfoxide reductase
RA 3,710,665 G→T 13.5% intergenic (+99/‑5) yiaD → / → ghrB multicopy suppressor of bamB; outer membrane lipoprotein/glyoxylate/hydroxypyruvate reductase B
RA 3,716,399 C→A 13.9% A453A (GCG→GCT glyS ← glycine tRNA synthetase, beta subunit
RA 3,717,788 C→A 94.7% P297P (CCG→CCT glyQ ← glycine tRNA synthetase, alpha subunit
RA 3,727,580 C→A 5.1% A167A (GCC→GCA xylH → D‑xylose ABC transporter permease subunit
RA 3,736,058 C→A 10.2% intergenic (‑166/‑35) yiaJ ← / → yiaK transcriptional repressor of yiaK‑S operon/2,3‑diketo‑L‑gulonate reductase, NADH‑dependent
RA 3,738,431 C→A 100% P90T (CCA→ACA)  yiaN → 2,3‑diketo‑L‑gulonate TRAP transporter large permease protein
RA 3,740,731 G→T 18.3% G96G (GGG→GGT lyxK → L‑xylulose kinase
RA 3,740,770 C→A 13.2% I109I (ATC→ATA lyxK → L‑xylulose kinase
RA 3,744,809 C→A 17.1% E140D (GAG→GAT yiaT ← putative outer membrane protein
RA 3,759,323 C→T 9.9% P1261S (CCC→TCC)  rhsA → Rhs family protein, putative polymorphic toxin; putative polysaccharide synthesis/export protein; putative neighboring cell growth inhibitor
RA 3,761,602 G→A 32.3% V22V (GTG→GTA yibG → TPR‑like repeat protein
RA 3,767,000 G→T 90.2% D454Y (GAC→TAC)  mtlA → fused mannitol‑specific PTS enzymes: IIA components/IIB components/IIC components
RA 3,774,427 T→G 12.9% intergenic (+50/‑148) lldD → / → trmL L‑lactate dehydrogenase, FMN‑linked/tRNA Leu mC34,mU34 2'‑O‑methyltransferase, SAM‑dependent
RA 3,777,581 T→G 14.9% A74A (GCA→GCC grxC ← glutaredoxin 3
RA 3,777,924 C→A 18.5% intergenic (‑122/+20) grxC ← / ← yibN glutaredoxin 3/putative rhodanese‑related sulfurtransferase
RA 3,778,219 C→A 12.6% D53Y (GAC→TAC)  yibN ← putative rhodanese‑related sulfurtransferase
RA 3,779,324 C→A 42.8% F235L (TTC→TTA gpmM → phosphoglycero mutase III, cofactor‑independent
RA 3,785,915 G→T 100% intergenic (‑4/+271) kbl ← / ← yibB glycine C‑acetyltransferase/YibB family protein, function unknown
RA 3,797,033 C→A 8.1% T155T (ACG→ACT waaB ← UDP‑D‑galactose:(glucosyl)lipopolysaccharide‑1, 6‑D‑galactosyltransferase
RA 3,798,296 G→A 11.0% L61F (CTC→TTC)  waaS ← lipopolysaccharide core biosynthesis protein
RA 3,799,108 C→A 47.5% R68L (CGG→CTG)  waaP ← kinase that phosphorylates core heptose of lipopolysaccharide
RA 3,799,227 G→T 12.8% V28V (GTC→GTA waaP ← kinase that phosphorylates core heptose of lipopolysaccharide
RA 3,809,236 G→T 5.2% pseudogene (6/48 nt) rph ← ribonuclease PH (defective);enzyme; Degradation of RNA; RNase PH
RA 3,810,195 C→A 100% R54S (CGT→AGT)  yicC → UPF0701 family protein
RA 3,815,043 C→A 16.9% R86S (CGT→AGT)  gmk → guanylate kinase
RA 3,816,601 A→T 100% H281L (CAC→CTC)  spoT → bifunctional (p)ppGpp synthetase II/ guanosine‑3',5'‑bis pyrophosphate 3'‑pyrophosphohydrolase
RA 3,816,686 G→T 22.5% S309S (TCG→TCT spoT → bifunctional (p)ppGpp synthetase II/ guanosine‑3',5'‑bis pyrophosphate 3'‑pyrophosphohydrolase
RA 3,818,010 C→A 100% H46N (CAT→AAT)  trmH → tRNA mG18‑2'‑O‑methyltransferase, SAM‑dependent
RA 3,819,936 C→A 45.5% T456K (ACG→AAG)  recG → ATP‑dependent DNA helicase
RA 3,822,340 A→C 6.2% Q12H (CAA→CAC xanP → xanthine permease
RA 3,825,702 C→A 100% K732N (AAG→AAT yicI ← putative alpha‑glucosidase
RA 3,828,206 T→A 21.4% S362C (AGT→TGT)  yicJ ← putative transporter
RA 3,829,020 G→T 17.4% F90L (TTC→TTA yicJ ← putative transporter
RA 3,830,197 C→A 100% intergenic (+281/‑116) yicT → / → setC pseudogene/putative arabinose efflux transporter
RA 3,830,311 G→T 100% intergenic (+395/‑2) yicT → / → setC pseudogene/putative arabinose efflux transporter
RA 3,830,819 T→G 6.9% F169L (TTT→TTG setC → putative arabinose efflux transporter
RA 3,834,958 G→T 20.7% Q48K (CAG→AAG)  nepI ← putative transporter
RA 3,837,177 C→T 8.7% intergenic (‑28/‑147) yicO ← / → ade putative adenine permease/cryptic adenine deaminase
RA 3,838,587 T→A 19.4% S422T (TCC→ACC)  ade → cryptic adenine deaminase
RA 3,839,034 C→A 21.5% Q571K (CAG→AAG)  ade → cryptic adenine deaminase
JC 3,841,409 +CAACCAG 14.9% coding (576/1320 nt) uhpC ← membrane protein regulates uhpT expression
RA 3,846,307 C→A 20.8% A14A (GCG→GCT ivbL ← ilvB operon leader peptide
RA 3,851,275 G→T 19.2% H164N (CAT→AAT)  yidJ ← sulfatase/phosphatase superfamily protein
RA 3,851,696 G→T 8.0% S23R (AGC→AGA yidJ ← sulfatase/phosphatase superfamily protein
RA 3,857,220 C→A 11.3% intergenic (‑257/‑39) glvC ← / → yidP pseudogene, arbutin specific enzyme IIC component of PTS;enzyme; Transport of small molecules: Carbohydrates, organic acids, alcohols; PTS system, arbutin‑like IIB component; PTS system, arbutin‑like IIC component/UTRA domain‑containing GntR family putative transcriptional regulator
RA 3,858,963 A→T 19.2% V224E (GTA→GAA)  yidE ← putative transporter
RA 3,860,159 C→A 100% P33P (CCG→CCT ibpB ← heat shock chaperone
RA 3,860,327 C→A 87.8% intergenic (‑70/+42) ibpB ← / ← ibpA heat shock chaperone/heat shock chaperone
RA 3,860,653 C→A 92.6% E44* (GAA→TAA)  ibpA ← heat shock chaperone
RA 3,863,438 G→T 5.7% M234I (ATG→ATT cbrA → colicin M resistance protein; FAD‑binding protein, putative oxidoreductase
RA 3,865,120 C→A 89.5% intergenic (‑30/+90) dgoT ← / ← dgoD D‑galactonate transporter/galactonate dehydratase
RA 3,865,863 T→A 7.0% T166S (ACC→TCC)  dgoD ← galactonate dehydratase
RA 3,867,062 C→A 40.5% R258L (CGC→CTC)  dgoK ← 2‑oxo‑3‑deoxygalactonate kinase
RA 3,874,397 C→A 14.3% R62L (CGC→CTC)  recF ← gap repair protein
RA 3,879,501 T→A 48.8% F356I (TTC→ATC)  yidC → membrane protein insertase
RA 3,882,020 G→T 16.4% intergenic (+151/‑70) tnaC → / → tnaA tryptophanase leader peptide/tryptophanase/L‑cysteine desulfhydrase, PLP‑dependent
RA 3,889,578 C→A 42.8% R131L (CGC→CTC)  purP ← adenine permease, high affinity; adenine:H+ symporter
RA 3,890,960 T→A 7.4% F32Y (TTC→TAC)  cbrB → PRK09823 family inner membrane protein, creBC regulon
RA 3,891,421 C→A 8.7% H14N (CAT→AAT)  cbrC → UPF0167 family protein
RA 3,892,304 C→A 9.4% P150P (CCG→CCT yieK ← putative 6‑phosphogluconolactonase
RA 3,894,972 G→T 11.0% G203G (GGC→GGA bglH ← carbohydrate‑specific outer membrane porin, cryptic
RA 3,896,944 C→A 35.3% V40L (GTA→TTA)  bglB ← cryptic phospho‑beta‑glucosidase B
RA 3,902,909 C→A 12.8% V284F (GTT→TTT)  pstC ← phosphate transporter subunit
RA 3,906,384 G→T 7.9% I215I (ATC→ATA glmS ← L‑glutamine:D‑fructose‑6‑phosphate aminotransferase
RA 3,910,416 C→A 7.1% R107L (CGT→CTT)  atpD ← F1 sector of membrane‑bound ATP synthase, beta subunit
RA 3,910,448 G→T 7.9% V96V (GTC→GTA atpD ← F1 sector of membrane‑bound ATP synthase, beta subunit
RA 3,910,487 C→A 12.1% A83A (GCG→GCT atpD ← F1 sector of membrane‑bound ATP synthase, beta subunit
RA 3,910,894 C→A 100% M244I (ATG→ATT atpG ← F1 sector of membrane‑bound ATP synthase, gamma subunit
RA 3,911,056 C→A 10.9% P190P (CCG→CCT atpG ← F1 sector of membrane‑bound ATP synthase, gamma subunit
RA 3,916,830 C→A 100% D71Y (GAT→TAT)  rsmG ← 16S rRNA m(7)G527 methyltransferase, SAM‑dependent; glucose‑inhibited cell‑division protein
RA 3,917,554 C→A 6.5% L480L (CTG→CTT mnmG ← 5‑methylaminomethyl‑2‑thiouridine modification at tRNA U34
RA 3,923,028 C→A 92.8% D476Y (GAC→TAC)  ravA ← hexameric AAA+ MoxR family ATPase, putative molecular chaperone
RA 3,923,775 G→T 8.8% H227N (CAT→AAT)  ravA ← hexameric AAA+ MoxR family ATPase, putative molecular chaperone
RA 3,926,831 G→T 92.1% D41Y (GAT→TAT)  rbsD → putative cytoplasmic sugar‑binding protein
RA 3,927,972 G→T 93.2% E279* (GAA→TAA)  rbsA → fused D‑ribose transporter subunits of ABC superfamily: ATP‑binding components
RA 3,933,204 C→T 5.3% D257N (GAT→AAT)  hsrA ← putative multidrug or homocysteine efflux system
RA 3,933,680 G→T 15.2% S98* (TCG→TAG)  hsrA ← putative multidrug or homocysteine efflux system
RA 3,934,476 G→T 9.7% P71Q (CCG→CAG)  yieP ← putative transcriptional regulator
RA 3,935,100 G→T 90.2% intergenic (‑413/‑68) yieP ← / → rrsC putative transcriptional regulator/16S ribosomal RNA of rrnC operon
RA 3,940,333 T→A 15.6% noncoding (17/76 nt) trpT → tRNA‑Trp
RA 3,945,503 A→T 53.1% pseudogene (602/663 nt) ilvG → pseudogene, acetolactate synthase 2 large subunit, valine‑insensitive; acetolactate synthase II, large subunit, cryptic, interrupted
RA 3,945,552 G→T 6.7% pseudogene (651/663 nt) ilvG → pseudogene, acetolactate synthase 2 large subunit, valine‑insensitive; acetolactate synthase II, large subunit, cryptic, interrupted
RA 3,946,072 G→T 12.1% D77Y (GAT→TAT)  ilvE → branched‑chain amino‑acid aminotransferase
RA 3,948,854 G→T 10.3% R55L (CGC→CTC)  ilvA → L‑threonine dehydratase, biosynthetic; also known as threonine deaminase
RA 3,952,817 T→G 5.4% intergenic (+12/+75) ilvC → / ← ppiC ketol‑acid reductoisomerase, NAD(P)‑binding/peptidyl‑prolyl cis‑trans isomerase C (rotamase C)
RA 3,956,165 C→A 44.4% E475D (GAG→GAT gpp ← guanosine pentaphosphatase/exopolyphosphatase
RA 3,960,036 G→A 100% R87H (CGC→CAC)  rho → transcription termination factor
RA 3,966,854 C→A 100% R325S (CGT→AGT)  rffG → dTDP‑glucose 4,6‑dehydratase
RA 3,967,474 G→T 92.7% A169A (GCG→GCT rffH → glucose‑1‑phosphate thymidylyltransferase
RA 3,968,673 C→A 9.4% T56T (ACC→ACA wecE → TDP‑4‑oxo‑6‑deoxy‑D‑glucose transaminase
RA 3,968,711 A→T 10.5% Q69L (CAG→CTG)  wecE → TDP‑4‑oxo‑6‑deoxy‑D‑glucose transaminase
RA 3,969,710 G→T 94.5% G25C (GGT→TGT)  wzxE → O‑antigen translocase
RA 3,972,296 G→T 9.7% E112D (GAG→GAT wzyE → putative ECA polysaccharide chain elongation protein
RA 3,977,650 A→T 48.7% intergenic (+97/+62) aslB → / ← aslA putative AslA‑specific sulfatase‑maturating enzyme/putative Ser‑type periplasmic non‑aryl sulfatase
RA 3,978,003 C→A 37.7% E455D (GAG→GAT aslA ← putative Ser‑type periplasmic non‑aryl sulfatase
RA 3,978,810 G→T 43.3% I186I (ATC→ATA aslA ← putative Ser‑type periplasmic non‑aryl sulfatase
RA 3,984,342 G→T 16.6% intergenic (‑216/‑171) hemC ← / → cyaA hydroxymethylbilane synthase/adenylate cyclase
RA 3,987,104 G→T 8.4% R106S (CGC→AGC)  cyaY ← iron‑dependent inhibitor of iron‑sulfur cluster formation; frataxin; iron‑binding and oxidizing protein
RA 3,988,075 T→A 100% V65E (GTG→GAG)  yifL → putative lipoprotein
RA 3,990,572 C→A 38.8% I10I (ATC→ATA yigB → 5‑amino‑6‑(5‑phospho‑D‑ribitylamino)uracil phosphatase; pyrimidine phosphatase; riboflavin synthesis
RA 3,994,076 A→T 100% L114* (TTA→TAA)  yigE ← DUF2233 family protein
RA 3,994,247 A→T 100% V57E (GTG→GAG)  yigE ← DUF2233 family protein
RA 3,994,758 G→T 14.8% intergenic (‑342/‑28) yigE ← / → corA DUF2233 family protein/magnesium/nickel/cobalt transporter
RA 3,996,070 G→T 11.8% F30L (TTC→TTA yigF ← putative inner membrane protein
RA 3,996,346 T→A 6.3% I70F (ATC→TTC)  yigG ← PRK11371 family inner membrane protein
RA 3,997,144 G→T 16.2% A132E (GCG→GAG)  rarD ← putative chloramphenical resistance permease
RA 3,999,692 G→T 12.8% D157Y (GAT→TAT)  recQ → ATP‑dependent DNA helicase
RA 4,001,030 G→T 5.6% V603F (GTT→TTT)  recQ → ATP‑dependent DNA helicase
RA 4,009,705 G→A 100% intergenic (‑176/‑86) ysgA ← / → udp putative carboxymethylenebutenolidase/uridine phosphorylase
RA 4,011,961 G→T 12.1% A423A (GCG→GCT rmuC → DNA recombination protein
RA 4,023,757 T→A 20.0% K192I (AAA→ATA)  fadB ← fused 3‑hydroxybutyryl‑CoA epimerase/delta(3)‑cis‑delta(2)‑trans‑enoyl‑CoA isomerase/enoyl‑CoA hydratase/3‑hydroxyacyl‑CoA dehydrogenase
RA 4,024,233 A→C 16.4% T33T (ACT→ACG fadB ← fused 3‑hydroxybutyryl‑CoA epimerase/delta(3)‑cis‑delta(2)‑trans‑enoyl‑CoA isomerase/enoyl‑CoA hydratase/3‑hydroxyacyl‑CoA dehydrogenase
RA 4,024,827 G→T 92.1% D103Y (GAT→TAT)  pepQ → proline dipeptidase
RA 4,035,421 G→T 94.0% intergenic (‑62/‑8) mobA ← / → yihD molybdopterin‑guanine dinucleotide synthase/DUF1040 protein YihD
RA 4,037,484 T→A 6.4% intergenic (+80/‑75) dsbA → / → yihF periplasmic protein disulfide isomerase I/DUF945 family protein
RA 4,041,798 C→A 40.2% L491L (CTC→CTA polA → fused DNA polymerase I 5'‑>3' polymerase/3'‑>5' exonuclease/5'‑>3' exonuclease
RA 4,046,172 A→T 93.2% K256N (AAA→AAT hemN → coproporphyrinogen III oxidase, SAM and NAD(P)H dependent, oxygen‑independent
RA 4,050,102 G→T 9.4% A431A (GCC→GCA glnA ← glutamine synthetase
RA 4,054,222 T→A 18.2% V139D (GTT→GAT)  yihL → putative DNA‑binding transcriptional regulator
RA 4,056,018 T→A 100% F138I (TTC→ATC)  yihN → MFS transporter family protein
RA 4,058,809 G→T 10.1% I106I (ATC→ATA yihO ← putative transporter
RA 4,062,424 G→T 100% I71I (ATC→ATA yihQ ← alpha‑glucosidase
RA 4,066,133 T→G 100% S267R (AGC→CGC)  yihU ← gamma‑hydroxybutyrate dehydrogenase, NADH‑dependent
RA 4,068,208 C→A 100% G60G (GGC→GGA yihW → DeoR family putative transcriptional regulator
RA 4,077,665 G→T 44.7% V506V (GTC→GTA fdoG ← formate dehydrogenase‑O, large subunit
RA 4,078,761 C→A 13.1% R141L (CGC→CTC)  fdoG ← formate dehydrogenase‑O, large subunit
RA 4,086,370 G→T 9.8% intergenic (‑187/+114) frvA ← / ← rhaM putative enzyme IIA component of PTS/L‑rhamnose mutarotase
RA 4,087,476 A→T 48.9% intergenic (‑126/‑188) rhaD ← / → rhaS pseudogene, truncated, rhamnulose‑phosphate aldolase/transcriptional activator of rhaBAD and rhaT
RA 4,087,754 C→A 41.7% H31N (CAT→AAT)  rhaS → transcriptional activator of rhaBAD and rhaT
RA 4,087,772 G→T 13.4% E37* (GAA→TAA)  rhaS → transcriptional activator of rhaBAD and rhaT
RA 4,088,850 C→A 6.6% R93S (CGT→AGT)  rhaR → transcriptional activator of rhaSR
RA 4,094,362 C→A 100% W181L (TGG→TTG)  cpxA ← sensory histidine kinase in two‑component regulatory system with CpxR
RA 4,095,124 C→T 41.6% G159S (GGT→AGT)  cpxR ← response regulator in two‑component regulatory system with CpxA
RA 4,097,282 C→A 43.9% R296R (CGG→AGG)  fieF → ferrous iron and zinc transporter
RA 4,097,822 G→T 100% E115* (GAA→TAA)  pfkA → 6‑phosphofructokinase I
RA 4,122,248 A→T 92.3% intergenic (+53/‑296) metL → / → metF Bifunctional aspartokinase/homoserine dehydrogenase 2/5,10‑methylenetetrahydrofolate reductase
RA 4,122,781 C→A 31.5% R80S (CGC→AGC)  metF → 5,10‑methylenetetrahydrofolate reductase
RA 4,125,407 C→A 6.3% H549N (CAT→AAT)  katG → catalase‑peroxidase HPI, heme b‑containing
RA 4,127,022 T→G 100% E188D (GAA→GAC yijF ← DUF1287 family protein
RA 4,128,613 G→T 11.0% I117I (ATC→ATA gldA ← glycerol dehydrogenase, NAD+ dependent; 1,2‑propanediol:NAD+ oxidoreductase
RA 4,131,163 C→A 8.9% T329T (ACG→ACT frwA ← putative PTS enzyme, Hpr component/enzyme I component/enzyme IIA component
RA 4,134,111 G→T 42.9% L63L (CTG→CTT pflD → putative glycine radical domain‑containing pyruvate formate‑lyase
RA 4,143,375 A→G 8.1% intergenic (‑349/+249) ppc ← / ← argE phosphoenolpyruvate carboxylase/acetylornithine deacetylase
RA 4,144,163 C→A 11.9% A205S (GCT→TCT)  argE ← acetylornithine deacetylase
RA 4,145,195 G→T 48.4% A89A (GCG→GCT argC → N‑acetyl‑gamma‑glutamylphosphate reductase, NAD(P)‑binding
RA 4,150,054 G→T 6.5% S222Y (TCT→TAT)  sthA ← pyridine nucleotide transhydrogenase, soluble
RA 4,150,197 G→T 19.8% H174Q (CAC→CAA sthA ← pyridine nucleotide transhydrogenase, soluble
RA 4,172,414 C→A 6.3% I414I (ATC→ATA rpoB → RNA polymerase, beta subunit
RA 4,173,059 C→A 40.6% F629L (TTC→TTA rpoB → RNA polymerase, beta subunit
RA 4,173,145 A→T 91.7% Q658L (CAG→CTG)  rpoB → RNA polymerase, beta subunit
RA 4,173,179 G→T 7.9% P669P (CCG→CCT rpoB → RNA polymerase, beta subunit
RA 4,176,823 G→T 100% D516Y (GAC→TAC)  rpoC → RNA polymerase, beta prime subunit
RA 4,178,969 G→T 9.5% R1231L (CGT→CTT)  rpoC → RNA polymerase, beta prime subunit
RA 4,179,520 C→A 5.2% intergenic (+19/‑194) rpoC → / → yjaZ RNA polymerase, beta prime subunit/stationary phase growth adaptation protein
RA 4,183,071 G→T 12.8% P145Q (CCG→CAG)  thiF ← adenylyltransferase, modifies ThiS C‑terminus
RA 4,186,367 G→T 43.3% Q124K (CAA→AAA)  rsd ← stationary phase protein, binds sigma 70 RNA polymerase subunit
RA 4,189,766 C→A 11.9% T112K (ACG→AAG)  yjaG → DUF416 domain protein
RA 4,193,578 G→T 6.3% D111Y (GAT→TAT)  zraR → fused DNA‑binding response regulator in two‑component regulatory system with ZraS: response regulator/sigma54 interaction protein
RA 4,195,623 G→T 10.0% G79G (GGC→GGA purD ← phosphoribosylglycinamide synthetase phosphoribosylamine‑glycine ligase
RA 4,207,552 G→T 91.1% M172I (ATG→ATT aceA → isocitrate lyase
RA 4,208,942 C→A 18.2% A140E (GCG→GAG)  aceK → isocitrate dehydrogenase kinase/phosphatase
RA 4,208,975 C→A 12.3% S151Y (TCT→TAT)  aceK → isocitrate dehydrogenase kinase/phosphatase
RA 4,210,835 G→C 14.3% C527W (TGC→TGG arpA ← ankyrin repeat protein
RA 4,211,576 G→T 100% S280R (AGC→AGA arpA ← ankyrin repeat protein
RA 4,211,803 G→A 100% P205S (CCT→TCT)  arpA ← ankyrin repeat protein
RA 4,214,392 G→T 8.0% G213C (GGC→TGC)  metH → homocysteine‑N5‑methyltetrahydrofolate transmethylase, B12‑dependent
RA 4,214,563 A→T 91.8% T270S (ACC→TCC)  metH → homocysteine‑N5‑methyltetrahydrofolate transmethylase, B12‑dependent
RA 4,215,252 G→T 9.4% E499D (GAG→GAT metH → homocysteine‑N5‑methyltetrahydrofolate transmethylase, B12‑dependent
RA 4,217,818 G→T 18.2% V54F (GTT→TTT)  yjbB → putative Na+/Pi‑cotransporter
RA 4,219,550 C→A 7.8% R174L (CGT→CTT)  pepE ← (alpha)‑aspartyl dipeptidase
RA 4,222,149 G→T 16.7% S338* (TCG→TAG)  lysC ← lysine‑sensitive aspartokinase 3
RA 4,225,841 A→C 7.8% K3T (AAA→ACA)  yjbE → extracellular polysaccharide production threonine‑rich protein
RA 4,230,913 A→T 100% W424R (TGG→AGG)  xylE ← D‑xylose transporter
RA 4,235,869 G→T 90.5% A160E (GCG→GAG)  malE ← maltose transporter subunit
RA 4,236,666 C→A 5.5% intergenic (‑319/‑46) malE ← / → malK maltose transporter subunit/fused maltose transport subunit, ATP‑binding component of ABC superfamily/regulatory protein
RA 4,242,509 C→T 93.0% L26F (CTC→TTC)  ubiC → chorismate‑‑pyruvate lyase
RA 4,245,537 G→T 6.0% N286K (AAC→AAA plsB ← glycerol‑3‑phosphate O‑acyltransferase
RA 4,247,427 G→T 44.5% D129Y (GAC→TAC)  lexA → transcriptional repressor of SOS regulon
RA 4,256,589 G→T 15.9% E294* (GAA→TAA)  alr → alanine racemase, biosynthetic, PLP‑binding
RA 4,257,593 C→T 11.8% N184N (AAC→AAT tyrB → tyrosine aminotransferase, tyrosine‑repressible, PLP‑dependent
RA 4,258,418 G→A 19.9% intergenic (+183/+319) tyrB → / ← yjbS tyrosine aminotransferase, tyrosine‑repressible, PLP‑dependent/uncharacterized protein
RA 4,259,065 C→A 25.3% intergenic (‑125/‑277) yjbS ← / → aphA uncharacterized protein/acid phosphatase/phosphotransferase, class B, non‑specific
RA 4,265,064 C→A 100% intergenic (‑95/‑335) yjcB ← / → yjcC putative inner membrane protein/putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 4,265,415 G→T 15.9% R6L (CGA→CTA)  yjcC → putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 4,266,665 G→T 19.0% D423Y (GAT→TAT)  yjcC → putative membrane‑anchored cyclic‑di‑GMP phosphodiesterase
RA 4,270,316 G→T 19.0% E137* (GAA→TAA)  yjcE → putative cation/proton antiporter
RA 4,274,748 C→A 18.0% R28L (CGC→CTC)  actP ← acetate transporter
RA 4,274,926 A→C 100% I72M (ATT→ATG yjcH ← DUF485 family inner membrane protein
RA 4,275,142 C→A 93.0% intergenic (‑1/+199) yjcH ← / ← acs DUF485 family inner membrane protein/acetyl‑CoA synthetase
RA 4,275,862 C→A 5.6% D480Y (GAT→TAT)  acs ← acetyl‑CoA synthetase
RA 4,276,940 G→T 22.2% F120L (TTC→TTA acs ← acetyl‑CoA synthetase
RA 4,277,386 G→T 11.0% intergenic (‑87/‑306) acs ← / → nrfA acetyl‑CoA synthetase/nitrite reductase, formate‑dependent, cytochrome
RA 4,281,581 G→T 20.1% D48Y (GAT→TAT)  nrfE → heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfE
RA 4,285,213 G→T 46.1% D269Y (GAT→TAT)  gltP → glutamate/aspartate:proton symporter
RA 4,286,311 C→A 38.6% S211I (AGC→ATC)  yjcO ← Sel1 family TPR‑like repeat protein
RA 4,288,086 G→T 8.0% F366L (TTC→TTA fdhF ← formate dehydrogenase‑H, selenopolypeptide subunit
RA 4,290,080 G→T 100% I256I (ATC→ATA mdtP ← outer membrane factor of efflux pump
RA 4,294,402 C→T 14.7% intergenic (‑182/+27) ytcA ← / ← yjcS putative inner membrane DUF1656 family protein; efflux pump associated/metallo‑beta‑lactamase superfamily protein
RA 4,297,485 G→C 90.6% G44G (GGC→GGG alsK ← D‑allose kinase
RA 4,297,846 C→A 100% M150I (ATG→ATT alsE ← allulose‑6‑phosphate 3‑epimerase
RA 4,301,569 G→T 47.0% V97V (GTC→GTA alsB ← D‑allose transporter subunit
RA 4,303,358 G→T 47.7% L64F (TTG→TTT rpiB → ribose 5‑phosphate isomerase B/allose 6‑phosphate isomerase
RA 4,303,614 T→A 100% *150R (TGA→AGA)  rpiB → ribose 5‑phosphate isomerase B/allose 6‑phosphate isomerase
RA 4,303,617 G→T 5.8% intergenic (+1/‑68) rpiB → / → yjdP ribose 5‑phosphate isomerase B/allose 6‑phosphate isomerase/putative periplasmic protein
RA 4,316,794 G→A 33.9% intergenic (‑243/‑158) yjdM ← / → crfC zinc‑ribbon family protein/clamp‑binding sister replication fork colocalization protein, dynamin‑related
RA 4,317,243 C→A 12.8% R98S (CGT→AGT)  crfC → clamp‑binding sister replication fork colocalization protein, dynamin‑related
RA 4,318,517 A→T 7.1% T522T (ACA→ACT crfC → clamp‑binding sister replication fork colocalization protein, dynamin‑related
RA 4,329,774 C→A 8.7% D189Y (GAC→TAC)  adiA ← arginine decarboxylase
RA 4,330,426 Δ1 bp 100% intergenic (‑88/+111) adiA ← / ← melR arginine decarboxylase/melibiose operon transcriptional regulator; autoregulator
RA 4,333,400 G→T 42.2% R72L (CGA→CTA)  melB → melibiose:sodium symporter
RA 4,335,003 A→T 16.9% Y125N (TAC→AAC)  yjdF ← DUF2238 family inner membrane protein
RA 4,336,196 G→T 39.0% V316V (GTC→GTA fumB ← anaerobic class I fumarate hydratase (fumarase B)
RA 4,337,717 G→T 46.9% A282E (GCG→GAG)  dcuB ← C4‑dicarboxylate transporter, anaerobic; DcuS co‑sensor
RA 4,341,023 A→T 100% Y153N (TAC→AAC)  dcuS ← sensory histidine kinase in two‑component regulatory system with DcuR, regulator of anaerobic fumarate respiration
RA 4,346,015 G→T 43.9% L72I (CTC→ATC)  dtpC ← dipeptide and tripeptide permease
RA 4,346,500 G→T 11.2% N645K (AAC→AAA cadA ← lysine decarboxylase, acid‑inducible
RA 4,355,939 C→A 14.2% E218* (GAA→TAA)  dcuA ← C4‑dicarboxylate antiporter
RA 4,357,095 A→C 47.2% V350V (GTT→GTG aspA ← aspartate ammonia‑lyase
RA 4,358,920 G→T 87.7% R147L (CGC→CTC)  fxsA → suppressor of F exclusion of phage T7
RA 4,358,943 G→T 5.0% D155Y (GAT→TAT)  fxsA → suppressor of F exclusion of phage T7
RA 4,373,522 C→T 14.8% intergenic (+85/‑134) epmA → / → yjeM Elongation Factor P Lys34 lysyltransferase/putative transporter
RA 4,373,880 G→T 9.8% M75I (ATG→ATT yjeM → putative transporter
RA 4,376,178 C→A 90.5% E1004* (GAA→TAA)  mscM ← mechanosensitive channel protein, miniconductance
RA 4,378,778 G→T 100% S137* (TCG→TAG)  mscM ← mechanosensitive channel protein, miniconductance
RA 4,381,462 G→A 11.6% E14E (GAG→GAA orn → oligoribonuclease
RA 4,382,218 C→A 6.0% noncoding (42/76 nt) glyV → tRNA‑Gly
RA 4,388,902 G→T 100% A558A (GCG→GCT mutL → methyl‑directed mismatch repair protein
RA 4,394,391 G→T 6.0% T63T (ACG→ACT yjeT → DUF2065 family protein
RA 4,394,875 G→T 91.4% A124A (GCG→GCT purA → adenylosuccinate synthetase
RA 4,396,598 A→T 100% E43V (GAA→GTA)  rnr → exoribonuclease R, RNase R
RA 4,399,304 C→A 13.9% I71I (ATC→ATA rlmB → 23S rRNA mG2251 2'‑O‑ribose methyltransferase, SAM‑dependent
RA 4,401,343 A→T 18.7% S75S (TCA→TCT yjfK → DUF2491 family protein
RA 4,402,105 A→T 15.9% I104F (ATT→TTT)  yjfL → UPF0719 family inner membrane protein
RA 4,402,850 G→T 89.6% L2L (CTG→CTT yjfC → ATP‑Grasp family ATPase
RA 4,404,169 G→T 5.4% A26A (GCG→GCT aidB → DNA alkylation damage repair protein; flavin‑containing DNA binding protein, weak isovaleryl CoA dehydrogenase
RA 4,405,730 G→T 8.3% intergenic (+13/+104) aidB → / ← yjfN DNA alkylation damage repair protein; flavin‑containing DNA binding protein, weak isovaleryl CoA dehydrogenase/DUF1471 family periplasmic protein
RA 4,407,017 C→T 12.9% I83I (ATC→ATT yjfP → acyl CoA esterase
RA 4,408,612 C→A 15.4% V277V (GTG→GTT ulaG ← L‑ascorbate 6‑phosphate lactonase
RA 4,412,786 G→T 5.8% E42* (GAA→TAA)  ulaE → L‑xylulose 5‑phosphate 3‑epimerase
RA 4,416,344 G→T 7.3% A140A (GCG→GCT rplI → 50S ribosomal subunit protein L9
RA 4,417,551 A→C 100% pseudogene (41/402 nt) ytfA → pseudogene, related to transcriptional regulators
RA 4,419,557 C→T 11.7% intergenic (+185/‑124) fklB → / → cycA FKBP‑type peptidyl‑prolyl cis‑trans isomerase (rotamase)/D‑alanine/D‑serine/glycine transporter
RA 4,421,791 G→T 12.9% R4S (CGC→AGC)  ytfE ← iron‑sulfur cluster repair protein RIC
RA 4,427,647 G→A 100% D42N (GAT→AAT)  ytfI → uncharacterized protein
RA 4,428,092 G→T 92.7% G190V (GGA→GTA)  ytfI → uncharacterized protein
RA 4,432,031 G→A 5.1% intergenic (‑38/‑168) msrA ← / → tamA methionine sulfoxide reductase A/translocation and assembly module for autotransporter export, outer membrane subunit
RA 4,442,839 C→A 14.0% A151E (GCG→GAG)  ytfT → inner membrane putative ABC superfamily sugar transporter permease
RA 4,449,002 C→A 15.7% I409I (ATC→ATA pmbA → putative antibiotic peptide MccB17 maturation peptidase
RA 4,456,233 G→T 5.5% I277I (ATC→ATA treR ← trehalose 6‑phosphate‑inducible trehalose regulon transcriptional repressor
RA 4,457,499 C→A 5.1% R20S (CGT→AGT)  mgtA → magnesium transporter
RA 4,458,254 T→A 100% V271V (GTT→GTA mgtA → magnesium transporter
RA 4,458,609 G→T 100% D390Y (GAT→TAT)  mgtA → magnesium transporter
RA 4,458,948 G→T 5.2% D503Y (GAT→TAT)  mgtA → magnesium transporter
RA 4,461,317 G→T 17.0% A299E (GCG→GAG)  pyrB ← aspartate carbamoyltransferase, catalytic subunit
RA 4,464,061 G→T 7.2% E41* (GAA→TAA)  bdcR → transcriptional repressor for divergent bdcA
RA 4,465,836 C→T 12.2% L195L (CTA→TTA)  yjgL → uncharacterized protein
RA 4,465,936 T→A 7.5% L228* (TTA→TAA)  yjgL → uncharacterized protein
RA 4,466,511 G→T 9.9% A420S (GCT→TCT)  yjgL → uncharacterized protein
RA 4,468,165 A→G 94.9% intergenic (‑37/‑125) argI ← / → rraB ornithine carbamoyltransferase 1/protein inhibitor of RNase E
RA 4,469,532 A→G 8.9% intergenic (‑178/‑15) yjgM ← / → yjgN putative acetyltransferase/DUF898 family inner membrane protein
RA 4,469,550 G→A 100% A2T (GCT→ACT)  yjgN → DUF898 family inner membrane protein
RA 4,470,017 G→A 100% M157I (ATG→ATA yjgN → DUF898 family inner membrane protein
RA 4,470,873 G→T 91.8% R928S (CGT→AGT)  valS ← valyl‑tRNA synthetase
RA 4,471,930 T→A 9.3% P575P (CCA→CCT valS ← valyl‑tRNA synthetase
RA 4,474,726 A→T 6.7% V348E (GTG→GAG)  pepA ← multifunctional aminopeptidase A: a cyteinylglycinase, transcription regulator and site‑specific recombination factor
RA 4,474,993 G→T 41.7% S259* (TCG→TAG)  pepA ← multifunctional aminopeptidase A: a cyteinylglycinase, transcription regulator and site‑specific recombination factor
RA 4,475,510 G→T 12.0% R87S (CGT→AGT)  pepA ← multifunctional aminopeptidase A: a cyteinylglycinase, transcription regulator and site‑specific recombination factor
RA 4,481,791 C→A 7.0% P184P (CCG→CCT idnT ← L‑idonate and D‑gluconate transporter
RA 4,482,573 A→T 14.9% L199Q (CTG→CAG)  idnO ← 5‑keto‑D‑gluconate‑5‑reductase
RA 4,494,721 G→A 91.9% A283T (GCC→ACC)  yjhB → putative transporter
RA 4,494,928 G→T 10.0% A352S (GCA→TCA)  yjhB → putative transporter
RA 4,495,349 G→T 46.5% K82N (AAG→AAT yjhC → putative oxidoreductase
RA 4,495,859 T→G 6.8% D252E (GAT→GAG yjhC → putative oxidoreductase
RA 4,505,141 G→T 5.3% R452S (CGT→AGT)  fecA ← ferric citrate outer membrane transporter
RA 4,507,551 G→T 6.1% R168S (CGT→AGT)  fecI ← RNA polymerase, sigma 19 factor
RA 4,510,255 G→T 17.1% intergenic (‑114/+233) yjhU ← / ← yjhF putative DNA‑binding transcriptional regulator; KpLE2 phage‑like element/putative transporter
RA 4,512,693 T→A 100% K407* (AAG→TAG)  yjhG ← putative dehydratase
RA 4,514,180 A→T 11.5% A216A (GCT→GCA yjhH ← putative lyase/synthase
RA 4,516,177 C→A 42.6% D177Y (GAT→TAT)  sgcR ← putative DNA‑binding transcriptional regulator
RA 4,519,217 A→T 14.2% F282I (TTC→ATC)  sgcC ← putative PTS system EIIC permease component
RA 4,520,701 G→T 6.2% G256G (GGC→GGA sgcX ← putative endoglucanase with Zn‑dependent exopeptidase domain
RA 4,522,074 T→A 40.9% pseudogene (54/261 nt) yjhY ← pseudogene, zinc finger protein family
RA 4,523,001 T→A 87.4% intergenic (‑1/+55) yjhP ← / ← yjhQ putative methyltransferase/putative acetyltransferase
RA 4,525,234 G→A 100% pseudogene (415/1029 nt) yjhR → pseudogene, helicase family; putative frameshift suppressor
RA 4,525,278 G→T 13.5% pseudogene (459/1029 nt) yjhR → pseudogene, helicase family; putative frameshift suppressor
RA 4,531,143 A→T 100% I124F (ATT→TTT)  fimB → tyrosine recombinase/inversion of on/off regulator of fimA
RA 4,531,461 G→A 45.8% intergenic (+85/‑393) fimB → / → fimE tyrosine recombinase/inversion of on/off regulator of fimA/tyrosine recombinase/inversion of on/off regulator of fimA
RA 4,535,507 C→A 46.7% R199R (CGG→AGG)  fimD → fimbrial usher outer membrane porin protein; FimCD chaperone‑usher
RA 4,535,723 G→T 10.9% D271Y (GAT→TAT)  fimD → fimbrial usher outer membrane porin protein; FimCD chaperone‑usher
RA 4,541,449 A→T 92.9% intergenic (‑336/‑4) gntP ← / → uxuA fructuronate transporter/mannonate hydrolase
RA 4,555,156 G→T 100% A171E (GCG→GAG)  yjiM ← putative 2‑hydroxyglutaryl‑CoA dehydratase
RA 4,555,620 T→G 15.7% E16D (GAA→GAC yjiM ← putative 2‑hydroxyglutaryl‑CoA dehydratase
RA 4,559,831 G→T 39.6% intergenic (+96/+148) yjiP → / ← yjiR pseudogene, transposase_31 family protein/putative DNA‑binding transcriptional regulator/putative aminotransferase
RA 4,562,043 C→A 100% intergenic (+311/‑188) yjiS → / → yjiT DUF1127 family protein/pseudogene
RA 4,564,939 G→T 14.1% pseudogene (1204/2937 nt) yjiV → pseudogene; conserved hypothetical protein
RA 4,567,114 G→A 13.8% S221F (TCT→TTT)  mcrC ← 5‑methylcytosine‑specific restriction enzyme McrBC, subunit McrC
RA 4,567,278 G→T 5.6% I166I (ATC→ATA mcrC ← 5‑methylcytosine‑specific restriction enzyme McrBC, subunit McrC
RA 4,567,552 C→A 14.7% R75L (CGA→CTA)  mcrC ← 5‑methylcytosine‑specific restriction enzyme McrBC, subunit McrC
RA 4,571,233 G→A 93.7% S16F (TCT→TTT)  hsdS ← specificity determinant for hsdM and hsdR
RA 4,572,227 G→T 17.9% I213I (ATC→ATA hsdM ← DNA methyltransferase M
RA 4,572,520 A→T 5.9% Y116N (TAC→AAC)  hsdM ← DNA methyltransferase M
RA 4,572,800 A→T 45.2% V22V (GTT→GTA hsdM ← DNA methyltransferase M
RA 4,575,640 C→A 7.4% pseudogene (993/3567 nt) hsdR ← pseudogene, premature stop codon, host restriction; endonuclease R
RA 4,584,255 A→C 9.0% L95L (CTT→CTG yjjL ← L‑galactonate transporter
RA 4,584,381 G→T 100% I53I (ATC→ATA yjjL ← L‑galactonate transporter
RA 4,584,756 A→T 93.3% *305K (TAA→AAA)  yjjM ← yjjMN operon transcriptional activator
RA 4,585,338 A→T 93.6% S111T (TCT→ACT)  yjjM ← yjjMN operon transcriptional activator
RA 4,586,074 G→T 5.1% V90F (GTT→TTT)  yjjN → L‑galactonate oxidoreductase
RA 4,586,139 C→A 40.1% V111V (GTC→GTA yjjN → L‑galactonate oxidoreductase
RA 4,586,861 G→T 16.7% intergenic (+32/+106) yjjN → / ← opgB L‑galactonate oxidoreductase/phosphoglycerol transferases I and II
RA 4,588,180 G→T 7.0% S360* (TCA→TAA)  opgB ← phosphoglycerol transferases I and II
RA 4,591,139 C→A 89.2% D66Y (GAT→TAT)  dnaT ← DNA biosynthesis protein (primosomal protein I)
RA 4,593,513 T→G 46.5% Y74D (TAT→GAT)  yjjQ → putative transcriptional regulator
RA 4,596,008 C→A 46.2% intergenic (‑26/+9) leuV ← / ← leuP tRNA‑Leu/tRNA‑Leu
RA 4,596,243 T→A 91.9% intergenic (‑25/+243) leuQ ← / ← rsmC tRNA‑Leu/16S rRNA m(2)G1207 methyltransferase, SAM‑dependent
RA 4,602,307 T→A 46.9% L27Q (CTG→CAG)  yjjU → putative patatin‑like family phospholipase
RA 4,604,139 A→T 5.4% intergenic (+62/+358) yjjV → / ← yjjW putative DNase/putative pyruvate formate lyase activating enzyme
RA 4,604,195 A→G 6.4% intergenic (+118/+302) yjjV → / ← yjjW putative DNase/putative pyruvate formate lyase activating enzyme
RA 4,604,320 T→C 6.3% intergenic (+243/+177) yjjV → / ← yjjW putative DNase/putative pyruvate formate lyase activating enzyme
RA 4,612,781 C→A 19.7% A399E (GCG→GAG)  yjjJ → putative protein kinase
RA 4,616,323 G→T 38.3% E199* (GAA→TAA)  radA → DNA repair protein
RA 4,617,009 G→T 19.5% A427A (GCG→GCT radA → DNA repair protein
RA 4,617,366 G→T 14.7% G79* (GGA→TGA)  nadR → trifunctional protein: nicotinamide mononucleotide adenylyltransferase, ribosylnicotinamide kinase, transcriptional repressor
RA 4,625,288 T→C 94.5% intergenic (‑161/‑50) rob ← / → creA right oriC‑binding transcriptional activator, AraC family/putative periplasmic protein
RA 4,629,872 G→T 8.4% D84E (GAC→GAA arcA ← response regulator in two‑component regulatory system with ArcB or CpxA

Unassigned missing coverage evidence
   seq id start end size ←reads reads→ gene description
* * ÷ CP009273 373844 375149 1306 183 [180] [179] 181 frmA–[frmR] frmA,[frmR]
* * ÷ CP009273 4100584 4101519 936 183 [179] [178] 182 [cdh]–tpiA [cdh],tpiA

Unassigned new junction evidence
  seq id position reads (cov) reads (cov) score skew freq annotation gene product
* ? CP009273 360104 =213 (0.810)224 (0.850) 130/278 NT 51.3% intergenic (‑38/+557) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 360286 NA (NA)intergenic (‑220/+375) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
* ? CP009273 = 360278NA (NA)8413 (34.050)
+TTAATTAA
195/262 NT 97.6% intergenic (‑212/+383) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 361823 222 (0.850)coding (831/834 nt) mhpR mhp operon transcriptional activator
* ? CP009273 360652 =277 (1.060)8441 (48.270)
+46 bp
186/186 NT 98.0% intergenic (‑586/+9) lacZ/lacI pseudogene, truncated/DNA‑binding transcriptional repressor
?CP009273 = 1317577 246 (0.940)coding (101/882 nt) yciV PHP domain protein
* ? CP009273 376716 =NA (NA)247 (0.940) 128/278 NT 98.0% intergenic (‑1/‑91) yaiX/insC1 pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase/IS2 repressor TnpA
?CP009273 566411 = 5 (0.020)coding (63/552 nt) ybcL inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family
* ? CP009273 = 378046NA (NA)266 (1.010) 143/278 NT 98.2% intergenic (+11/+1) insD1/yaiX IS2 transposase TnpB/pseudogene, interrupted by IS2A, acetyltransferase homolog; nonfunctional; interruped by IS2; putative transferase
?CP009273 = 566415 5 (0.020)coding (67/552 nt) ybcL inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; secreted protein, UPF0098 family
* ? CP009273 776825 =155 (0.590)23 (0.090)
+G
12/276 NT 12.1% noncoding (1/76 nt) lysZ tRNA‑Lys
?CP009273 = 2514488 182 (0.690)noncoding (216/1345 nt) IS186 repeat region
* ? CP009273 1203246 =13 (0.050)7 (0.030) 5/246 NT 30.8% coding (290/630 nt) stfP e14 prophage; uncharacterized protein
?CP009273 1205075 = 20 (0.090)pseudogene (1/501 nt) stfE pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
* ? CP009273 = 120326116 (0.060)8 (0.030) 6/246 NT 31.9% coding (305/630 nt) stfP e14 prophage; uncharacterized protein
?CP009273 = 1205058 20 (0.090)pseudogene (18/501 nt) stfE pseudogene, e14 prophage; side tail fiber protein fragment family;Phage or Prophage Related
* ? CP009273 1635219 =10 (0.040)260 (1.010) 138/274 NT 96.3% intergenic (‑377/+377) essQ/cspB Qin prophage; putative S lysis protein/Qin prophage; cold shock protein
?CP009273 = 2063752 NA (NA)noncoding (1/1331 nt) IS2 repeat region
* ? CP009273 = 163522310 (0.040)215 (0.820) 128/278 NT 95.6% intergenic (‑381/+373) essQ/cspB Qin prophage; putative S lysis protein/Qin prophage; cold shock protein
?CP009273 = 1645805 NA (NA)intergenic (+11/‑3) insD1/intQ IS2 transposase TnpB;IS, phage, Tn; Transposon‑related functions; extrachromosomal; transposon related/pseudogene, Qin prophage; phage integrase family;Phage or Prophage Related
* ? CP009273 = 2811301186 (0.710)10 (0.040) 8/238 NT 5.9% intergenic (‑82/+117) argQ/argZ tRNA‑Arg/tRNA‑Arg
?CP009273 2811851 = 160 (0.710)noncoding (58/77 nt) argV tRNA‑Arg
* ? CP009273 = 3180783NA (NA)266 (1.030) 139/274 NT 90.0% pseudogene (4/2445 nt) yqiG pseudogene; fimbrial export usher family;putative membrane; Not classified; putative membrane protein
?CP009273 = 3833569 30 (0.110)intergenic (‑216/‑6) nlpA/yicS cytoplasmic membrane lipoprotein‑28/putative periplasmic protein
* ? CP009273 3744959 =265 (1.010)526 (2.010) 198/278 NT 67.6% coding (270/741 nt) yiaT putative outer membrane protein
?CP009273 = 3752673 240 (0.910)coding (549/1845 nt) selB selenocysteinyl‑tRNA‑specific translation factor
* ? CP009273 3833562 =27 (0.100)189 (0.730) 116/276 NT 87.6% intergenic (‑209/‑13) nlpA/yicS cytoplasmic membrane lipoprotein‑28/putative periplasmic protein
?CP009273 4487999 = NA (NA)intergenic (+242/‑90) intB/insC1 pseudogene, integrase homology;IS, phage, Tn; Phage‑related functions and prophages; KpLE2 phage‑like element; P4‑like integrase/IS2 repressor TnpA
* ? CP009273 3920822 =207 (0.790)71 (0.270) 50/278 NT 23.2% coding (308/993 nt) asnA asparagine synthetase A
?CP009273 = 3921005 264 (1.010)coding (491/993 nt) asnA asparagine synthetase A